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The map label for this gene is 119866838

Identifier: 119866838

GI number: 119866838

Start: 831817

End: 833037

Strand: Reverse

Name: 119866838

Synonym: Mkms_0784

Alternate gene names: NA

Gene position: 833037-831817 (Counterclockwise)

Preceding gene: 119866842

Following gene: 119866837

Centisome position: 14.52

GC content: 71.83

Gene sequence:

>1221_bases
ATGAAGACCCGGGCGGATGTGGTCGTTGTCGGCGCCGGACCTGCGGGTTCGGCTGCCGCGGCCTGGGCGGCCCGCGCCGG
TCGCGACGTGTTGGTGATCGACTCCGCCCGCTTCCCGCGCGACAAGGCGTGCGGTGACGGGCTGACCCCGCGGGCGGTCG
CCGAACTCGAACGCCTCGGCCTCGGGCCGTGGCTGGACACCCGCATCCGCCACCGCGGTCTGCGGATGTCGGGATTCGGC
GCGGCCGTGGAGGTCGCCTGGCCCGGCCCGTCGTTCCCGTCCACCGGCAGCGCGGTGCCGCGCACCGAACTCGACGACCG
GATCCGCTCCGTCGCCGCCGACGACGGCGCCAAGATGCTCCTCGGCACCAAAGCCGTTGGTGTCGAACATGATTCGTCGG
GACGCGTGGAGACGTTGACGCTGGACTCGGGTGAGGAGGTCGGTGTCGGGACCTTGATCGTCGCCGACGGGGCGCGGTCG
ACACTGGGCCGTGCGCTCGGCCGGCAGTGGCATCAGCAGACCGTCTACGGCGTCGCGGTGCGCGGTTACCTCGCCAGCCC
GCGCAGCGACGAACCGTGGATCACGTCGCACCTGGAACTGCGGTCACCGGAGGGCAAGGTGCTGCCCGGCTACGGCTGGA
TCTTCCCGCTGGGCAACGGTGAGGTGAACATCGGCGTCGGCGCCCTGGCGACCGAAAAACGGCCCGCCGACGCCGCTTTG
CGGCCGCTGATGTCGCATTACACGGCGTTGCGGCGCGAGGAATGGGGCTTCGACGGTGAGCCGCGCGCACCGCTGTCCGC
GCTGCTGCCGATGGGCGGCGCGGTGTCGGGAGTCGCCGGCCCCAACTGGATGCTGATCGGGGACGCCGCGGCGTGTGTGA
ACCCGCTCAACGGCGAAGGCATCGACTACGGGTTGGAGACCGGCCGGCTGGCCGCCGACCTGCTCGGCTCCAGTGACCTC
TCACAGGCGTGGCCCGCCGTGCTGAGCGACCACTACGCCCGCGGATTCTCCGTCGCGCGCCGGCTGGCGTTGCTGCTCAC
GCTGCCGAGATTCCTCCCGCTGACCGGTCCGGTGGCGATGCGGTCGACGGCGCTGATGCGCATTGCGGTCCGGGTGATGG
GCAACCTGGTCACCGACGAGGACGCCGACTGGATCGCCCGGGTGTGGCGCGCGGGTGGTCTGGCCTCGCGCGGCCTGGAC
GCGCGCAAACCGTTCAGCTGA

Upstream 100 bases:

>100_bases
GCGACTCCGGCGCGGACGTCGGCCGCGAAGGCCGCGTCGCCGAAGTCCACGCCCGCCACCACAGTCGCCGGTGTCCTCAC
CCTGCCAACATACTGTGACA

Downstream 100 bases:

>100_bases
TCAGCCGGCGACGCGGCCGGTCGTCGTCCGTGCGACTCGCATCGGTCAGCGCGAGCGCGATGAGGATGTCCGCGAAGGTG
ATGAACAGCCCCATCCAGTA

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKTRADVVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFG
AAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARS
TLGRALGRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAAL
RPLMSHYTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDL
SQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLD
ARKPFS

Sequences:

>Translated_406_residues
MKTRADVVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFG
AAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARS
TLGRALGRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAAL
RPLMSHYTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDL
SQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLD
ARKPFS
>Mature_406_residues
MKTRADVVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLGLGPWLDTRIRHRGLRMSGFG
AAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKMLLGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARS
TLGRALGRQWHQQTVYGVAVRGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAAL
RPLMSHYTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEGIDYGLETGRLAADLLGSSDL
SQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAMRSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLD
ARKPFS

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 42889; Mature: 42889

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRADVVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLG
CCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHC
LGPWLDTRIRHRGLRMSGFGAAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKML
CCCCHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
LGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRALGRQWHQQTVYGVAV
EEEEEECCEECCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEE
RGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAAL
EEEECCCCCCCCCEEEEEEEECCCCCEECCCEEEEECCCCEEEEEEEEEECCCCCHHHHH
RPLMSHYTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCCCC
IDYGLETGRLAADLLGSSDLSQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAM
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCCCCCCCC
>Mature Secondary Structure
MKTRADVVVVGAGPAGSAAAAWAARAGRDVLVIDSARFPRDKACGDGLTPRAVAELERLG
CCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHC
LGPWLDTRIRHRGLRMSGFGAAVEVAWPGPSFPSTGSAVPRTELDDRIRSVAADDGAKML
CCCCHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEE
LGTKAVGVEHDSSGRVETLTLDSGEEVGVGTLIVADGARSTLGRALGRQWHQQTVYGVAV
EEEEEECCEECCCCCEEEEEECCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEE
RGYLASPRSDEPWITSHLELRSPEGKVLPGYGWIFPLGNGEVNIGVGALATEKRPADAAL
EEEECCCCCCCCCEEEEEEEECCCCCEECCCEEEEECCCCEEEEEEEEEECCCCCHHHHH
RPLMSHYTALRREEWGFDGEPRAPLSALLPMGGAVSGVAGPNWMLIGDAAACVNPLNGEG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEECHHHHCCCCCCCC
IDYGLETGRLAADLLGSSDLSQAWPAVLSDHYARGFSVARRLALLLTLPRFLPLTGPVAM
CCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RSTALMRIAVRVMGNLVTDEDADWIARVWRAGGLASRGLDARKPFS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA