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The map label for this gene is actII-3 [H]

Identifier: 119866585

GI number: 119866585

Start: 582705

End: 584729

Strand: Reverse

Name: actII-3 [H]

Synonym: Mkms_0531

Alternate gene names: 119866585

Gene position: 584729-582705 (Counterclockwise)

Preceding gene: 119866587

Following gene: 119866584

Centisome position: 10.19

GC content: 71.51

Gene sequence:

>2025_bases
ATGGCAGGTCGATTCTCCTGGGTGGTGGCGTTGCTGGTGGTGCTCGTCTCCGGCGGGCTGATGGGTGTGCTCAGCGGCGG
CGAGTCGAGTTCGCAGTCACCGGTCTCGGTGCCGACGGATGCGGAATCGGCCAAGGTCAACGCCTTACGCAGCGAGTTCC
CCGGCGGCGATCAGGCGCCGGCGATCCTCGTCGTGACCCGCACCGACGGCGCAGCGCTGTCCCCCGCCGACATCGCCGCC
ACCGAGGCGGCGCGCGGCCGCATGCTCGACGCCGCCCAGAGCGCGCCTGCCGGTCCGCCGGTGATCGTCAGCGAGGACGA
CAAGGCCGCCATCGCCACCGTGCCGCTCGCCACCGACCTGTCCGGGTTCGGGCTCAACGACGCCGTCAAGGGTCTGCGGG
AGGCCGCCGCCGACGGACTGCCCGGCGACCTACGGGCCGAGGTGACCGGCGGGCCCGCATTCGGCGCCGACATCGCGAAC
TCCTTCTCCGGCGCCAACGTCACCCTGCTGGCGGTGACGGCCGCCGTCGTCGCACTGCTGCTGATCGTCACCTACCGGTC
ACCGGTGCTGTTCCTGGTGCCGTTGCTGGTGATCGGGTTCGCCGACCGGGTGGCGGCCGTGGTGGGCACCGCGATCGCCG
AGGCCGTCGGCATGTCCCCCGACGGGTCGACCTCCGGCATCACCAGCGTGCTGGTGTTCGGCGCCGGCACCAACTACGCG
CTGCTGCTGATCTCCCGGTACCGGGAGGAACTGGGCCGCAATGGCGATCACCGCGAAGCGCTCGCTGTCGCCGTGCGCGC
CGCCGGACCGGCCATCCTGGCGAGCAACGCCACCGTGGTGCTCGCCCTGCTCACGCTGGTGTTCGCGTCGGCGCCGAGCA
CCCGCGCCCTCGGCGTACAGGCCGCCGCCGGCCTGGTGGTCGCGGCCGTCTTCGTACTGCTGGTGCTGCCCGCCCTGCTG
CGATTGTTCGGCAAGAAACTGTTCTGGCCGCTCATCCCGAAGGAAGGCGCCGCACCGCTGACCGACAGCGGACTGTGGCA
CCGCATCGCCGCCGGCGTCTCACGCCGTCCCGCCGTCGTCGCCGTCGCGTCGATCGGTGCGCTGGCCGTGCTGTGCACCG
GCCTGCTGTTCACCCCGATCGGGCTGACCCAGACCGAGCAGTTCCGGGTGCAGGCCGAATCGGTGACCGGCTACGAAACC
CTGGCCGACCACTTCCCGAGCGGGTTGACCGATCCGACCCGCGTCATCGGGCCCTCCGACAAGACCGCCGAGCTCCAGCG
CGCCATCTCCGAGACGCCGGGCGTCGTGTCGGCCGACCCGGCGGGCACCTCCCCGACCGGGCTCACGCAGTGGTCGGTGG
TGCTGTCCGCCGAACCCGCCTCCGACGAGGCGTTCTCGACCGTGGACGCGCTGCGCGAGAACGTGCGTGGGGTGGATTCG
TCGGCGCTGGTCGGTGGTTCCGACGCCCAGGCGCGCGACATCAGCAGCGCCGCCTCGCGTGACCGCATGGTGGTGATCCC
GACGATCCTCGCCGTCGTCCTCGTGGTGCTGTACGTCCTGCTGCGCTCCGCGCTCGCGCCGCTGATCCTGGTCGCGGTGA
CAGTGCTCAGCGCACTGGCCGCGCTGGGTCTCGGCGGCTGGGCCAGCGTGCACCTGTTCGGCTTCCCGGCGCTCGACGAC
ACGACGCCGCTGTTCGCGTTCCTGTTCCTGGTGGCCCTCGGCGTGGACTACACGATCTTCCTGGTCACCCGGGCGCGGGA
GGAGACGCCGGACCACGGCACCCGCCAGGGCATCGTGCGCGCGGTGTCGGCGACCGGCGCCGTCATCACCAGCGCGGGCA
TCGTGCTGGCCGCGGTGTTCTGCGTGCTGGGGGTGTTGCCGCTGATCGTGCTCACGCAGTTGGGCATCATCGTCGGCCTC
GGCATCCTGCTCGACACGTTCCTGGTGCGCACGGTCATCATCCCGGCCCTGTTCACGTTGATCGGGCCGAAGATCTGGTG
GCCCGCGCTGCGCGCATCGCCGTAA

Upstream 100 bases:

>100_bases
GGCGATCAGCGCTTCGAGCGCGGCGCGGTCGGCGTCAGCCACTCGACGAGGATAGGTCGGCAGATGTTCAGTTTCTGAAA
TATCGGGAATAGTGGTCGGT

Downstream 100 bases:

>100_bases
TCCCGCTCCGCTCCCACGCGCGTACGTTCGGTAGGTATGACAGGCACGACTGGAGCATCGACGGCGCCCCCGCTCCCGCC
GCTGCACATGCGGCGCACCG

Product: MMPL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MAGRFSWVVALLVVLVSGGLMGVLSGGESSSQSPVSVPTDAESAKVNALRSEFPGGDQAPAILVVTRTDGAALSPADIAA
TEAARGRMLDAAQSAPAGPPVIVSEDDKAAIATVPLATDLSGFGLNDAVKGLREAAADGLPGDLRAEVTGGPAFGADIAN
SFSGANVTLLAVTAAVVALLLIVTYRSPVLFLVPLLVIGFADRVAAVVGTAIAEAVGMSPDGSTSGITSVLVFGAGTNYA
LLLISRYREELGRNGDHREALAVAVRAAGPAILASNATVVLALLTLVFASAPSTRALGVQAAAGLVVAAVFVLLVLPALL
RLFGKKLFWPLIPKEGAAPLTDSGLWHRIAAGVSRRPAVVAVASIGALAVLCTGLLFTPIGLTQTEQFRVQAESVTGYET
LADHFPSGLTDPTRVIGPSDKTAELQRAISETPGVVSADPAGTSPTGLTQWSVVLSAEPASDEAFSTVDALRENVRGVDS
SALVGGSDAQARDISSAASRDRMVVIPTILAVVLVVLYVLLRSALAPLILVAVTVLSALAALGLGGWASVHLFGFPALDD
TTPLFAFLFLVALGVDYTIFLVTRAREETPDHGTRQGIVRAVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGL
GILLDTFLVRTVIIPALFTLIGPKIWWPALRASP

Sequences:

>Translated_674_residues
MAGRFSWVVALLVVLVSGGLMGVLSGGESSSQSPVSVPTDAESAKVNALRSEFPGGDQAPAILVVTRTDGAALSPADIAA
TEAARGRMLDAAQSAPAGPPVIVSEDDKAAIATVPLATDLSGFGLNDAVKGLREAAADGLPGDLRAEVTGGPAFGADIAN
SFSGANVTLLAVTAAVVALLLIVTYRSPVLFLVPLLVIGFADRVAAVVGTAIAEAVGMSPDGSTSGITSVLVFGAGTNYA
LLLISRYREELGRNGDHREALAVAVRAAGPAILASNATVVLALLTLVFASAPSTRALGVQAAAGLVVAAVFVLLVLPALL
RLFGKKLFWPLIPKEGAAPLTDSGLWHRIAAGVSRRPAVVAVASIGALAVLCTGLLFTPIGLTQTEQFRVQAESVTGYET
LADHFPSGLTDPTRVIGPSDKTAELQRAISETPGVVSADPAGTSPTGLTQWSVVLSAEPASDEAFSTVDALRENVRGVDS
SALVGGSDAQARDISSAASRDRMVVIPTILAVVLVVLYVLLRSALAPLILVAVTVLSALAALGLGGWASVHLFGFPALDD
TTPLFAFLFLVALGVDYTIFLVTRAREETPDHGTRQGIVRAVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGL
GILLDTFLVRTVIIPALFTLIGPKIWWPALRASP
>Mature_673_residues
AGRFSWVVALLVVLVSGGLMGVLSGGESSSQSPVSVPTDAESAKVNALRSEFPGGDQAPAILVVTRTDGAALSPADIAAT
EAARGRMLDAAQSAPAGPPVIVSEDDKAAIATVPLATDLSGFGLNDAVKGLREAAADGLPGDLRAEVTGGPAFGADIANS
FSGANVTLLAVTAAVVALLLIVTYRSPVLFLVPLLVIGFADRVAAVVGTAIAEAVGMSPDGSTSGITSVLVFGAGTNYAL
LLISRYREELGRNGDHREALAVAVRAAGPAILASNATVVLALLTLVFASAPSTRALGVQAAAGLVVAAVFVLLVLPALLR
LFGKKLFWPLIPKEGAAPLTDSGLWHRIAAGVSRRPAVVAVASIGALAVLCTGLLFTPIGLTQTEQFRVQAESVTGYETL
ADHFPSGLTDPTRVIGPSDKTAELQRAISETPGVVSADPAGTSPTGLTQWSVVLSAEPASDEAFSTVDALRENVRGVDSS
ALVGGSDAQARDISSAASRDRMVVIPTILAVVLVVLYVLLRSALAPLILVAVTVLSALAALGLGGWASVHLFGFPALDDT
TPLFAFLFLVALGVDYTIFLVTRAREETPDHGTRQGIVRAVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLG
ILLDTFLVRTVIIPALFTLIGPKIWWPALRASP

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 68748; Mature: 68616

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRFSWVVALLVVLVSGGLMGVLSGGESSSQSPVSVPTDAESAKVNALRSEFPGGDQAP
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
AILVVTRTDGAALSPADIAATEAARGRMLDAAQSAPAGPPVIVSEDDKAAIATVPLATDL
EEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCEEEEECCHHCC
SGFGLNDAVKGLREAAADGLPGDLRAEVTGGPAFGADIANSFSGANVTLLAVTAAVVALL
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
LIVTYRSPVLFLVPLLVIGFADRVAAVVGTAIAEAVGMSPDGSTSGITSVLVFGAGTNYA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEECCCCHH
LLLISRYREELGRNGDHREALAVAVRAAGPAILASNATVVLALLTLVFASAPSTRALGVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHH
AAAGLVVAAVFVLLVLPALLRLFGKKLFWPLIPKEGAAPLTDSGLWHRIAAGVSRRPAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEE
AVASIGALAVLCTGLLFTPIGLTQTEQFRVQAESVTGYETLADHFPSGLTDPTRVIGPSD
EHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
KTAELQRAISETPGVVSADPAGTSPTGLTQWSVVLSAEPASDEAFSTVDALRENVRGVDS
HHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
SALVGGSDAQARDISSAASRDRMVVIPTILAVVLVVLYVLLRSALAPLILVAVTVLSALA
CCEECCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLGGWASVHLFGFPALDDTTPLFAFLFLVALGVDYTIFLVTRAREETPDHGTRQGIVR
HHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHH
AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVRTVIIPALFTL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGPKIWWPALRASP
HCCHHHCCHHCCCC
>Mature Secondary Structure 
AGRFSWVVALLVVLVSGGLMGVLSGGESSSQSPVSVPTDAESAKVNALRSEFPGGDQAP
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
AILVVTRTDGAALSPADIAATEAARGRMLDAAQSAPAGPPVIVSEDDKAAIATVPLATDL
EEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHCCCCCCCEEEECCCCCEEEEECCHHCC
SGFGLNDAVKGLREAAADGLPGDLRAEVTGGPAFGADIANSFSGANVTLLAVTAAVVALL
CCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
LIVTYRSPVLFLVPLLVIGFADRVAAVVGTAIAEAVGMSPDGSTSGITSVLVFGAGTNYA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEECCCCHH
LLLISRYREELGRNGDHREALAVAVRAAGPAILASNATVVLALLTLVFASAPSTRALGVQ
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHH
AAAGLVVAAVFVLLVLPALLRLFGKKLFWPLIPKEGAAPLTDSGLWHRIAAGVSRRPAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEE
AVASIGALAVLCTGLLFTPIGLTQTEQFRVQAESVTGYETLADHFPSGLTDPTRVIGPSD
EHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHHHCCCHHHHHHHCCCCCCCCCCCCCCCC
KTAELQRAISETPGVVSADPAGTSPTGLTQWSVVLSAEPASDEAFSTVDALRENVRGVDS
HHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCC
SALVGGSDAQARDISSAASRDRMVVIPTILAVVLVVLYVLLRSALAPLILVAVTVLSALA
CCEECCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALGLGGWASVHLFGFPALDDTTPLFAFLFLVALGVDYTIFLVTRAREETPDHGTRQGIVR
HHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHH
AVSATGAVITSAGIVLAAVFCVLGVLPLIVLTQLGIIVGLGILLDTFLVRTVIIPALFTL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGPKIWWPALRASP
HCCHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1878971; 12000953 [H]