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The map label for this gene is puuP [H]

Identifier: 119866297

GI number: 119866297

Start: 265345

End: 266853

Strand: Reverse

Name: puuP [H]

Synonym: Mkms_0242

Alternate gene names: 119866297

Gene position: 266853-265345 (Counterclockwise)

Preceding gene: 119866298

Following gene: 119866296

Centisome position: 4.65

GC content: 68.26

Gene sequence:

>1509_bases
ATGACCCAGACGCCGCCCGAGACCAACTTGGCACCCGAAACCGACCAGCTGCCGCACCGCCGCCTGCCGTTCTGGGTGGC
ACTGGCCATGTCGGTGGCGCTCGTCGGTCCGACGCTGGCCATGTCCGGTAACGGACAGGGCCTCATCGGCACCGTGGGCA
AGGCCATCCCGCTGGTCTTCCTGATCGGTCTGATCGGCGTCTCCCTGGTCGGGTACAGCTTCGTGCGGCTGACCCGCCAC
CTCAACCACGCCGGGTCGGCATACGGTCTGGTCGGCGGCACCATCGGACCGCGCGCGGGCTTCTTCTCCGGCTTCGCGAT
GCTCGGTGCCTACGTCGGCTTCTCGATCGGCACACTGGCGCTGACCGCCGCGTTCACCAACGCGTTCATCGCGCAACTGC
AACCCGACGCCGAAGACCCCTACCAGGTGCCGTGGCTGCTGGTGGTGCTGGTGGGTGCGGGGATCTCGTTCCTGTTGGCG
GGCCGCGACATCCGGCTGCTGGCGAAGATCCTGCTCGGCATCGAAGGCATCGGCATCCTCGCCATGGTGATACTGGTCGC
CGTCATCTTCGCCAAGGGCGGGGCGCCGACGACGGGCGTCGACTTCAGCGTGTTCACCTTCGACGGGGTCTCCGCGTCCG
CGGTGCTCAGCGGCGTGGTGGCCGCCTTCCTGTCCTGGGCCGGTTTCGAGGCCTGCGCCTCGATGGGCGAGGAGACCGAC
GATCCCCGCCGCAACATCCCCCGCGCCCTCGGCGGCACCCTGCTGCTCACCGGTGTGCTATTCGTCGTCGTGATGTTCGC
CCAGGTCATCGGGTTCGGCACCGACGAGGCCGGCCTGGCCGCCTTCCAGGGCTCCGGGAACACGCTGGGCGACTTGGGCA
GCACCTATGTCGGACAGTGGTTCTCGCTGTTGATCATCTTCACCGCGACGGTCGCGGCGTTCGGCTGCCACCTGGCCACC
TCGGCCACCTCCGGTCGCATGCTCTACGCGTTCGGCCGCGACGGGTTCGGTCCGAAAGCGTTGGCGCACATCCACGCCGA
GACCGGTGGCCCGCGGCGGGCCACCTGGCTGGTCGTCGGCGTGGCACTGGTCGTCGACCTGATCTGCGGTGCGCTCGACT
GGCCCGACATGGGCACCGGCAACGACGCGATCGACACCTACTTCCTGTTCGCCGTCGCGGGTTCGGTGTGCCTGATGGTG
TGCTACCTGCTGGTCGAGATCGCCGCGGCCTGGTTCGTCGGCGCACCGAAGTTCGTCGGTGTGCACGGCGGGACGGGCAA
GGTGCTCGGTCTGCTGCTGCCACTGCTCGGCGCGGTGGTGATCGCGGTGGTGTTGTGGTTCAACGTCAAGGACGCCGAGA
CGTGGTCGGCCGCACCGCTTCTCGGATTGTACTGGTGCGCAATCGGTTTGATCATCGCGCTGGCAGCGTCCGGAATCGCC
AAACGGGTCGGTGAGTCGCTGAGCCGTGAGCTCGAGCTCAGCCCGCCGGACGGCCGACCGGTCAGCTGA

Upstream 100 bases:

>100_bases
GCCACGAGCTGACCACCTACGGCGACCGTCCGCCCGCCGAGACCACCCAGGCGCTGCGCCTCGCCTGGAGCTGTTGACCA
CCGCCGAGAGGAAACCCCCG

Downstream 100 bases:

>100_bases
GAGCCGCCGGTGGGCTACGTTGGCGGCGACGGGGCCGCAGGGAAGGTCGACGACGAGGAGGTCGCGAAGTATGCCGGTTG
GTGATCGCACCGATGTGTTC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTQTPPETNLAPETDQLPHRRLPFWVALAMSVALVGPTLAMSGNGQGLIGTVGKAIPLVFLIGLIGVSLVGYSFVRLTRH
LNHAGSAYGLVGGTIGPRAGFFSGFAMLGAYVGFSIGTLALTAAFTNAFIAQLQPDAEDPYQVPWLLVVLVGAGISFLLA
GRDIRLLAKILLGIEGIGILAMVILVAVIFAKGGAPTTGVDFSVFTFDGVSASAVLSGVVAAFLSWAGFEACASMGEETD
DPRRNIPRALGGTLLLTGVLFVVVMFAQVIGFGTDEAGLAAFQGSGNTLGDLGSTYVGQWFSLLIIFTATVAAFGCHLAT
SATSGRMLYAFGRDGFGPKALAHIHAETGGPRRATWLVVGVALVVDLICGALDWPDMGTGNDAIDTYFLFAVAGSVCLMV
CYLLVEIAAAWFVGAPKFVGVHGGTGKVLGLLLPLLGAVVIAVVLWFNVKDAETWSAAPLLGLYWCAIGLIIALAASGIA
KRVGESLSRELELSPPDGRPVS

Sequences:

>Translated_502_residues
MTQTPPETNLAPETDQLPHRRLPFWVALAMSVALVGPTLAMSGNGQGLIGTVGKAIPLVFLIGLIGVSLVGYSFVRLTRH
LNHAGSAYGLVGGTIGPRAGFFSGFAMLGAYVGFSIGTLALTAAFTNAFIAQLQPDAEDPYQVPWLLVVLVGAGISFLLA
GRDIRLLAKILLGIEGIGILAMVILVAVIFAKGGAPTTGVDFSVFTFDGVSASAVLSGVVAAFLSWAGFEACASMGEETD
DPRRNIPRALGGTLLLTGVLFVVVMFAQVIGFGTDEAGLAAFQGSGNTLGDLGSTYVGQWFSLLIIFTATVAAFGCHLAT
SATSGRMLYAFGRDGFGPKALAHIHAETGGPRRATWLVVGVALVVDLICGALDWPDMGTGNDAIDTYFLFAVAGSVCLMV
CYLLVEIAAAWFVGAPKFVGVHGGTGKVLGLLLPLLGAVVIAVVLWFNVKDAETWSAAPLLGLYWCAIGLIIALAASGIA
KRVGESLSRELELSPPDGRPVS
>Mature_501_residues
TQTPPETNLAPETDQLPHRRLPFWVALAMSVALVGPTLAMSGNGQGLIGTVGKAIPLVFLIGLIGVSLVGYSFVRLTRHL
NHAGSAYGLVGGTIGPRAGFFSGFAMLGAYVGFSIGTLALTAAFTNAFIAQLQPDAEDPYQVPWLLVVLVGAGISFLLAG
RDIRLLAKILLGIEGIGILAMVILVAVIFAKGGAPTTGVDFSVFTFDGVSASAVLSGVVAAFLSWAGFEACASMGEETDD
PRRNIPRALGGTLLLTGVLFVVVMFAQVIGFGTDEAGLAAFQGSGNTLGDLGSTYVGQWFSLLIIFTATVAAFGCHLATS
ATSGRMLYAFGRDGFGPKALAHIHAETGGPRRATWLVVGVALVVDLICGALDWPDMGTGNDAIDTYFLFAVAGSVCLMVC
YLLVEIAAAWFVGAPKFVGVHGGTGKVLGLLLPLLGAVVIAVVLWFNVKDAETWSAAPLLGLYWCAIGLIIALAASGIAK
RVGESLSRELELSPPDGRPVS

Specific function: Imports putrescine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=469, Percent_Identity=25.1599147121535, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082023, Length=475, Percent_Identity=23.7894736842105, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51961; Mature: 51830

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPPETNLAPETDQLPHRRLPFWVALAMSVALVGPTLAMSGNGQGLIGTVGKAIPLVF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHH
LIGLIGVSLVGYSFVRLTRHLNHAGSAYGLVGGTIGPRAGFFSGFAMLGAYVGFSIGTLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTAAFTNAFIAQLQPDAEDPYQVPWLLVVLVGAGISFLLAGRDIRLLAKILLGIEGIGIL
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCHHHH
AMVILVAVIFAKGGAPTTGVDFSVFTFDGVSASAVLSGVVAAFLSWAGFEACASMGEETD
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DPRRNIPRALGGTLLLTGVLFVVVMFAQVIGFGTDEAGLAAFQGSGNTLGDLGSTYVGQW
CHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
FSLLIIFTATVAAFGCHLATSATSGRMLYAFGRDGFGPKALAHIHAETGGPRRATWLVVG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHEEECCCCCCCHHHHHHHH
VALVVDLICGALDWPDMGTGNDAIDTYFLFAVAGSVCLMVCYLLVEIAAAWFVGAPKFVG
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VHGGTGKVLGLLLPLLGAVVIAVVLWFNVKDAETWSAAPLLGLYWCAIGLIIALAASGIA
ECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KRVGESLSRELELSPPDGRPVS
HHHHHHHHCCEECCCCCCCCCC
>Mature Secondary Structure 
TQTPPETNLAPETDQLPHRRLPFWVALAMSVALVGPTLAMSGNGQGLIGTVGKAIPLVF
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHH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HHHHHHHHCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]