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The map label for this gene is 119855316

Identifier: 119855316

GI number: 119855316

Start: 125440

End: 126429

Strand: Reverse

Name: 119855316

Synonym: Mkms_5930

Alternate gene names: NA

Gene position: 126429-125440 (Counterclockwise)

Preceding gene: 119855317

Following gene: 119855311

Centisome position: 58.33

GC content: 70.71

Gene sequence:

>990_bases
GTGCCCAGCAGGTCCAAGCTCTCTGTGCGCGACCCCGCGTTCGCGCCGATGCTGGCCACCCTGGGCGCCGCACCCTCCGG
CGCCGCCCATGCCACCGAGTGGAAATTTGACGGGCAGCGCGCGACCGTCGTCGTCGAGCACGGCGCGGTGGTGGTGTTCA
CCCGCAACGGGATGGAAGTGACTCGAACCTTCCCTGAACTTCAGTCGATCGCCGCGGCGGTCGGCGATCGCCGCATGGTG
CTCGACGGCGAAATCGTGGCCCTCGACACCGAAGGCCGGCCGTCGTTCACCCGGCTGCAGCGCCGTTGGCCCCAGCAGCG
CCGACCCAGCGCCGAGCTGCTCCGCGAGGTGCCCTGCCGCGTGATGGCCTTCGACGTCCTGCGGCTCGACGGCCGCGACA
CCACCGCACTGCCCTACATCGAGCGCCGCGAGCTGCTCGACGACGTGATGGTGGCCAAGTCGCGTGTCCTGACCGTGCCG
GCCGCCCTGCACGACGTGGACCCCGCAGACGCACTCGAGGCGGCCGCGCTGCACGGCATGGAAGGCATCGTGGTCAAGAG
GCTCGACTCGCCGTACCGGCCCGGGCAGCGCAGCCCCGACTGGACGAAAGTCCCGGTCCGCGCCACCTGCGAGCTGCTGA
TCGCCGGCTATTGGTGTGCCGGCGGCCCGGGCGGACGCAGCTGTGTGGGCTCGCTGCTGGTGGCCGGCTACAACCCCGAC
GGCGACCTGGTAGCCATTGGCCAGGTCGGCACCGGGTTCAGCGCCACCACCCGCCGGCGGCTGTTCGACCAGCTGCAGCC
GATCCGGCGCACCACCTCACCCGTCGCCAACCGGGTCGAGCTGTCCGGCGTGCGGTTCGTGGAACCGTGCTACGTCGCCG
AGATCGCCTACCGCGAATACGTTCCGGGCCGCTGGCTGCGGCACGCCTCATTCAAGGGTTGCCGCGAGGTGGCGGACCTC
TCGCAGATTCAGATCCCGAACTGCGCATAG

Upstream 100 bases:

>100_bases
ATGCCCGCACCGACCACCTGACCCGCAACAGCGGTGATGCAGGCTGCATCACCGCACGATCACGAGTCGGCCACCACCGC
GTCACGCGTACCGTCAAAAG

Downstream 100 bases:

>100_bases
CCGCCTACTTGCGGCGCACGCCGGCGGCGACCGCCAGCCCGGCGGCCACCACCACAAGCACCCGGCTGTTGCCGATGTCG
GCCAGGCCCTCGACGCTGCC

Product: DNA ligase (ATP)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPSRSKLSVRDPAFAPMLATLGAAPSGAAHATEWKFDGQRATVVVEHGAVVVFTRNGMEVTRTFPELQSIAAAVGDRRMV
LDGEIVALDTEGRPSFTRLQRRWPQQRRPSAELLREVPCRVMAFDVLRLDGRDTTALPYIERRELLDDVMVAKSRVLTVP
AALHDVDPADALEAAALHGMEGIVVKRLDSPYRPGQRSPDWTKVPVRATCELLIAGYWCAGGPGGRSCVGSLLVAGYNPD
GDLVAIGQVGTGFSATTRRRLFDQLQPIRRTTSPVANRVELSGVRFVEPCYVAEIAYREYVPGRWLRHASFKGCREVADL
SQIQIPNCA

Sequences:

>Translated_329_residues
MPSRSKLSVRDPAFAPMLATLGAAPSGAAHATEWKFDGQRATVVVEHGAVVVFTRNGMEVTRTFPELQSIAAAVGDRRMV
LDGEIVALDTEGRPSFTRLQRRWPQQRRPSAELLREVPCRVMAFDVLRLDGRDTTALPYIERRELLDDVMVAKSRVLTVP
AALHDVDPADALEAAALHGMEGIVVKRLDSPYRPGQRSPDWTKVPVRATCELLIAGYWCAGGPGGRSCVGSLLVAGYNPD
GDLVAIGQVGTGFSATTRRRLFDQLQPIRRTTSPVANRVELSGVRFVEPCYVAEIAYREYVPGRWLRHASFKGCREVADL
SQIQIPNCA
>Mature_328_residues
PSRSKLSVRDPAFAPMLATLGAAPSGAAHATEWKFDGQRATVVVEHGAVVVFTRNGMEVTRTFPELQSIAAAVGDRRMVL
DGEIVALDTEGRPSFTRLQRRWPQQRRPSAELLREVPCRVMAFDVLRLDGRDTTALPYIERRELLDDVMVAKSRVLTVPA
ALHDVDPADALEAAALHGMEGIVVKRLDSPYRPGQRSPDWTKVPVRATCELLIAGYWCAGGPGGRSCVGSLLVAGYNPDG
DLVAIGQVGTGFSATTRRRLFDQLQPIRRTTSPVANRVELSGVRFVEPCYVAEIAYREYVPGRWLRHASFKGCREVADLS
QIQIPNCA

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=278, Percent_Identity=31.294964028777, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71985269, Length=260, Percent_Identity=28.0769230769231, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320038, Length=284, Percent_Identity=29.5774647887324, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24762424, Length=247, Percent_Identity=29.5546558704453, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 36089; Mature: 35958

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRSKLSVRDPAFAPMLATLGAAPSGAAHATEWKFDGQRATVVVEHGAVVVFTRNGMEV
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEECCEEEEEECCCCEE
TRTFPELQSIAAAVGDRRMVLDGEIVALDTEGRPSFTRLQRRWPQQRRPSAELLREVPCR
HHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCHHHHHHHHCCHHCCCHHHHHHHCCHH
VMAFDVLRLDGRDTTALPYIERRELLDDVMVAKSRVLTVPAALHDVDPADALEAAALHGM
HEEEEHEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEECCHHHHCCCHHHHHHHHHHCCC
EGIVVKRLDSPYRPGQRSPDWTKVPVRATCELLIAGYWCAGGPGGRSCVGSLLVAGYNPD
CCCEEEECCCCCCCCCCCCCCEECCHHHHEEEHEEEEEECCCCCHHHHHHHHHEEEECCC
GDLVAIGQVGTGFSATTRRRLFDQLQPIRRTTSPVANRVELSGVRFVEPCYVAEIAYREY
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHC
VPGRWLRHASFKGCREVADLSQIQIPNCA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PSRSKLSVRDPAFAPMLATLGAAPSGAAHATEWKFDGQRATVVVEHGAVVVFTRNGMEV
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEECCEEEEEECCCCEE
TRTFPELQSIAAAVGDRRMVLDGEIVALDTEGRPSFTRLQRRWPQQRRPSAELLREVPCR
HHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCHHHHHHHHCCHHCCCHHHHHHHCCHH
VMAFDVLRLDGRDTTALPYIERRELLDDVMVAKSRVLTVPAALHDVDPADALEAAALHGM
HEEEEHEEECCCCCCCCCHHHHHHHHHHHHHHHHHEEECCHHHHCCCHHHHHHHHHHCCC
EGIVVKRLDSPYRPGQRSPDWTKVPVRATCELLIAGYWCAGGPGGRSCVGSLLVAGYNPD
CCCEEEECCCCCCCCCCCCCCEECCHHHHEEEHEEEEEECCCCCHHHHHHHHHEEEECCC
GDLVAIGQVGTGFSATTRRRLFDQLQPIRRTTSPVANRVELSGVRFVEPCYVAEIAYREY
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEECHHHHHHHHHHHC
VPGRWLRHASFKGCREVADLSQIQIPNCA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]