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The map label for this gene is yvrH [H]

Identifier: 119776726

GI number: 119776726

Start: 4226151

End: 4227281

Strand: Reverse

Name: yvrH [H]

Synonym: Sama_3594

Alternate gene names: 119776726

Gene position: 4227281-4226151 (Counterclockwise)

Preceding gene: 119776727

Following gene: 119776725

Centisome position: 98.17

GC content: 52.61

Gene sequence:

>1131_bases
ATGCGTGATAAACCGGAACTCTTGTTGGTGGATGACTCTCCCAACGAAATTCGTATTTTGATGGAAATTCTCAAGCAGGA
TTATCGTCTCAACGTGGCCACCAATGGTGCCCAGGCGCTGGAGATGATTGCCGAAACCACCCCTGATCTGGTGTTGATGG
ACGTGGTGATGGAACCCATGGACGGTTATGAGGCCTGTAGCCGTCTTAAGCTGGACTGGCCCGAATTGCCGGTGATATTT
GTGTCGGCGAATACGGAAACCGATGAAATCCTCAAAGGCTTTGCTGCCGGCGGGCAGGACTACATCACCAAACCTTTTGA
GCCCAAGATATTGCTGCGTAAGGTACGGCTTACCCTGTCACAGACAGCGCAGCGGCTGCAACTCTCAAGCGAAAAAAGGG
AAGCCACAGCCATGGTGATGGCCGCCATGAACAGTGCGGCTGATATCAGTGTAGTGGTGAACTTTCTGCGGGCTTGTACC
AAGCACAGGGATGCTCAGGCCCTGGTGCAGGAAATCTGCCGTGCCAGTGCCAATTTTGGGGTGCAGGTGTGCAGTCGTAT
TGTGGGCGTGGCTGAAAAACCCTTTTATGCCGCCAGTCAGGGGGCCGTGCAGCCCCTTGAGCAGGTGTTGATGGACAGGG
CTTCGGAGTTTGAATGCCGTATGCTGGAAAAAGGTAATCGGCTGATTTTAAAGTTTTCATCCGTGGTGATGCTGGTGAAA
AATCTGCCGGAAGAACCTTCGCGGGCCGGTGAGCTTAAAGACTATTTGCTTATCCTGATGGAAGCGGCACACGACCTCAA
TCAGCGGATCACCGCCGACACCAGCGTGGCGCAGCAGCGGCTTTCCCTCATGATGGACACCATCGACAAGTCCAGGGTAG
CCCTTCAGGAAATCAAGGACTTTCAGGTAGACCACAAGGAAAAAAACCTCGCAATCATGAATCAGTTAATGCTGGAAATT
GAAACCGGCTTTGTATCCATGGGGCTGTCGGAAGAGCAGGAAGTCTGGATAGCCGGTGTTATCAAAAACAAGCTGGATGA
GAGTCTGGCGCACCTGGAATCAGGACTGACGGTCGACCGCAAGCTCCATGGCATAGTCGAGCAGCTTGATGCTCTGGTGC
AAACCTTTTAA

Upstream 100 bases:

>100_bases
GATACCAGGATGATTTCAACCTGTTTATCAAACTATTCGATGCATTTGATGTGCGCGGAGCCAAATCGGTTTTGGCCAGA
ATGCTGGGGAGGGAAACCTG

Downstream 100 bases:

>100_bases
TCGGCGCAGTCACAGCCCCGGCGCCAAAGTAACCCGGCGCCGAGGGCGGTGATCAGCATCAGGGTCGGTAACACCACAAA
GTGCACCATGGGTGAGGCTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MRDKPELLLVDDSPNEIRILMEILKQDYRLNVATNGAQALEMIAETTPDLVLMDVVMEPMDGYEACSRLKLDWPELPVIF
VSANTETDEILKGFAAGGQDYITKPFEPKILLRKVRLTLSQTAQRLQLSSEKREATAMVMAAMNSAADISVVVNFLRACT
KHRDAQALVQEICRASANFGVQVCSRIVGVAEKPFYAASQGAVQPLEQVLMDRASEFECRMLEKGNRLILKFSSVVMLVK
NLPEEPSRAGELKDYLLILMEAAHDLNQRITADTSVAQQRLSLMMDTIDKSRVALQEIKDFQVDHKEKNLAIMNQLMLEI
ETGFVSMGLSEEQEVWIAGVIKNKLDESLAHLESGLTVDRKLHGIVEQLDALVQTF

Sequences:

>Translated_376_residues
MRDKPELLLVDDSPNEIRILMEILKQDYRLNVATNGAQALEMIAETTPDLVLMDVVMEPMDGYEACSRLKLDWPELPVIF
VSANTETDEILKGFAAGGQDYITKPFEPKILLRKVRLTLSQTAQRLQLSSEKREATAMVMAAMNSAADISVVVNFLRACT
KHRDAQALVQEICRASANFGVQVCSRIVGVAEKPFYAASQGAVQPLEQVLMDRASEFECRMLEKGNRLILKFSSVVMLVK
NLPEEPSRAGELKDYLLILMEAAHDLNQRITADTSVAQQRLSLMMDTIDKSRVALQEIKDFQVDHKEKNLAIMNQLMLEI
ETGFVSMGLSEEQEVWIAGVIKNKLDESLAHLESGLTVDRKLHGIVEQLDALVQTF
>Mature_376_residues
MRDKPELLLVDDSPNEIRILMEILKQDYRLNVATNGAQALEMIAETTPDLVLMDVVMEPMDGYEACSRLKLDWPELPVIF
VSANTETDEILKGFAAGGQDYITKPFEPKILLRKVRLTLSQTAQRLQLSSEKREATAMVMAAMNSAADISVVVNFLRACT
KHRDAQALVQEICRASANFGVQVCSRIVGVAEKPFYAASQGAVQPLEQVLMDRASEFECRMLEKGNRLILKFSSVVMLVK
NLPEEPSRAGELKDYLLILMEAAHDLNQRITADTSVAQQRLSLMMDTIDKSRVALQEIKDFQVDHKEKNLAIMNQLMLEI
ETGFVSMGLSEEQEVWIAGVIKNKLDESLAHLESGLTVDRKLHGIVEQLDALVQTF

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=138, Percent_Identity=26.8115942028986, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788550, Length=239, Percent_Identity=28.8702928870293, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=188, Percent_Identity=30.8510638297872, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789809, Length=138, Percent_Identity=28.9855072463768, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=107, Percent_Identity=33.6448598130841, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790860, Length=117, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 42096; Mature: 42096

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKPELLLVDDSPNEIRILMEILKQDYRLNVATNGAQALEMIAETTPDLVLMDVVMEPM
CCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCC
DGYEACSRLKLDWPELPVIFVSANTETDEILKGFAAGGQDYITKPFEPKILLRKVRLTLS
CHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
QTAQRLQLSSEKREATAMVMAAMNSAADISVVVNFLRACTKHRDAQALVQEICRASANFG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
VQVCSRIVGVAEKPFYAASQGAVQPLEQVLMDRASEFECRMLEKGNRLILKFSSVVMLVK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHH
NLPEEPSRAGELKDYLLILMEAAHDLNQRITADTSVAQQRLSLMMDTIDKSRVALQEIKD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQVDHKEKNLAIMNQLMLEIETGFVSMGLSEEQEVWIAGVIKNKLDESLAHLESGLTVDR
HCCCCCHHHHHHHHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
KLHGIVEQLDALVQTF
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRDKPELLLVDDSPNEIRILMEILKQDYRLNVATNGAQALEMIAETTPDLVLMDVVMEPM
CCCCCCEEEEECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHCCC
DGYEACSRLKLDWPELPVIFVSANTETDEILKGFAAGGQDYITKPFEPKILLRKVRLTLS
CHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
QTAQRLQLSSEKREATAMVMAAMNSAADISVVVNFLRACTKHRDAQALVQEICRASANFG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
VQVCSRIVGVAEKPFYAASQGAVQPLEQVLMDRASEFECRMLEKGNRLILKFSSVVMLVK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHH
NLPEEPSRAGELKDYLLILMEAAHDLNQRITADTSVAQQRLSLMMDTIDKSRVALQEIKD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQVDHKEKNLAIMNQLMLEIETGFVSMGLSEEQEVWIAGVIKNKLDESLAHLESGLTVDR
HCCCCCHHHHHHHHHHHHHHHHCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
KLHGIVEQLDALVQTF
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]