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The map label for this gene is ompR [H]

Identifier: 119776642

GI number: 119776642

Start: 4144996

End: 4145721

Strand: Direct

Name: ompR [H]

Synonym: Sama_3510

Alternate gene names: 119776642

Gene position: 4144996-4145721 (Clockwise)

Preceding gene: 119776638

Following gene: 119776643

Centisome position: 96.26

GC content: 56.2

Gene sequence:

>726_bases
ATGGGACAGGAAACCTCCAAGATTCTGGTCGTTGATGATGATATGAGACTCAGAGCCCTGCTGGAGCGCTATCTGGTGGA
GCAGGGATTTCAGGTCAGAGCAGCCGCCAACGCCGAGCAAATGGACCGGCTGCTGGAGCGCGAGAATTTTCATTTACTGG
TATTGGATTTGATGCTGCCCGGTGAGGATGGCCTGTCTATTTGCCGGCGATTGCGCCAGACCGGCAGCCCCCTGCCTATT
ATCATGCTCACTGCCAAAGGCGATGAAGTCGACCGCATTATCGGCCTTGAGCTGGGTGCAGATGATTACCTGCCCAAACC
CTTTAATCCACGGGAACTGCTGGCGCGTATCAAAGCCGTGATGCGCCGTCAAACTCAGGAAATTCCCGGTGCGCCGGCGC
AGCAGGAAGAAGAAGTGGGTTTTGGTGAGTTTCATCTCAATCTGGCTACCCGCGAAATGTATCGCGGTGACGAGTCCATT
GCTCTCACCAGCGGCGAGTTTGCCGTGCTTAAGGTCTTGGTGACGCATCCACGTGAACCCCTCTCCCGGGATAAGCTGAT
GAATCTGGCCCGGGGCCGCGATTATTCGGCACTGGAGCGTTCCATCGACGTGCAGGTATCCCGCCTTCGACGCCTGATTG
AAAAAGATCCCGCCAATCCAAGGTATATCCAAACCGTGTGGGGCCTGGGCTATGTGTTTGTACCCGACGGCAGCGCCCGT
CGTTAA

Upstream 100 bases:

>100_bases
CGGGTGCTTTTTGCGTACAAAGTGGCTAAATTTAGGATATTCGGTCACTTTTTCGGTTAAGATTCCGAAAACTTGCGTGC
CAATTTGAGGGGAAGGATAC

Downstream 100 bases:

>100_bases
GCCCGGAGCAAAATCATGAAACTTCGCTGGTGGCAGCGCTTGCTGCCCCGCAGCGCCTTCAGTCAAACCGTGATGCTGAT
AGGCTGTTTGCTGTTGATTA

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MGQETSKILVVDDDMRLRALLERYLVEQGFQVRAAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGSPLPI
IMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQEIPGAPAQQEEEVGFGEFHLNLATREMYRGDESI
ALTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGSAR
R

Sequences:

>Translated_241_residues
MGQETSKILVVDDDMRLRALLERYLVEQGFQVRAAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGSPLPI
IMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQEIPGAPAQQEEEVGFGEFHLNLATREMYRGDESI
ALTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGSAR
R
>Mature_240_residues
GQETSKILVVDDDMRLRALLERYLVEQGFQVRAAANAEQMDRLLERENFHLLVLDLMLPGEDGLSICRRLRQTGSPLPII
MLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAVMRRQTQEIPGAPAQQEEEVGFGEFHLNLATREMYRGDESIA
LTSGEFAVLKVLVTHPREPLSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGSARR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=80.5084745762712, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.117903930131, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=38.3620689655172, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=35.4166666666667, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI2367329, Length=236, Percent_Identity=40.2542372881356, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=32.4894514767932, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=34.8739495798319, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=35.7758620689655, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=36.4035087719298, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=233, Percent_Identity=33.0472103004292, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=31.6017316017316, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.0396475770925, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27409; Mature: 27278

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQETSKILVVDDDMRLRALLERYLVEQGFQVRAAANAEQMDRLLERENFHLLVLDLMLP
CCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQTGSPLPIIMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTQEIPGAPAQQEEEVGFGEFHLNLATREMYRGDESIALTSGEFAVLKVLVTHPREP
HHHHHHHCCCCCCCCHHCCCCCEEEEEHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGSAR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC
R
C
>Mature Secondary Structure 
GQETSKILVVDDDMRLRALLERYLVEQGFQVRAAANAEQMDRLLERENFHLLVLDLMLP
CCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCEEEEEEEECC
GEDGLSICRRLRQTGSPLPIIMLTAKGDEVDRIIGLELGADDYLPKPFNPRELLARIKAV
CCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHH
MRRQTQEIPGAPAQQEEEVGFGEFHLNLATREMYRGDESIALTSGEFAVLKVLVTHPREP
HHHHHHHCCCCCCCCHHCCCCCEEEEEHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCC
LSRDKLMNLARGRDYSALERSIDVQVSRLRRLIEKDPANPRYIQTVWGLGYVFVPDGSAR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCEEEECCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]