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The map label for this gene is torC [H]

Identifier: 119776603

GI number: 119776603

Start: 4100553

End: 4101116

Strand: Reverse

Name: torC [H]

Synonym: Sama_3471

Alternate gene names: 119776603

Gene position: 4101116-4100553 (Counterclockwise)

Preceding gene: 119776609

Following gene: 119776600

Centisome position: 95.24

GC content: 48.23

Gene sequence:

>564_bases
ATGAACTGGCGTGCACTATTCAAACCCAGCGCGAAATACTCAATATTTGCCCTGCTGTTGGTAGGTGTTGTGGTTGGCGT
GGTGGGCTACTTTGCGACTCAAACCACCTTGCATATGACCAGTACAGACGAGTTCTGTATGAGCTGTCACAGCAACCATT
CACTGAAAGACGAAGTATTGGCCTCGGCTCACGGCAACAATAAAAACGGTATTGTTGTGCAGTGTCAGCAGTGCCACATT
GCTCAGGAACCTTTCGCTTACCTGAAGAAGAAAATCATCGTATCCAAGGACGTTATCGGTTTCCTGACCATCGATGGTTT
CAACACTCAGGAATGGCTGGAAGCAAACCGTAAAGAACAAGCGGACCTGGCCCGTGACTATCTGCGTTCCATCGACTCAT
CCACCTGTCAGAACTGCCACAATCGTATTTACGAAAATCAGTCTGAGAACATGAGCAAGATGGCCGTGCGCATGCACAGT
AACAACTTCAAGAAAGATCCTGAAAGTCGCAAGACCTGTATCGATTGCCACAAGGGTGTTGCCCACCCCTATCCAAAGAG
TTGA

Upstream 100 bases:

>100_bases
TTCGCTATAAAATCCCGGTTAGCATCAAATTTCTTCAACCAAAATTACCCTACTATGGGGCTACTAAAAAAATAACCCTA
AAAATTTAGGAGATAGAGTG

Downstream 100 bases:

>100_bases
TAACAGCCCTTGCGATAGTGGCACTTTCGCCAGGAATAACCCGATAGCAAAAAGCCCCGATTACGGGGCTTTTTTGTTGG
GTGGCTCTAGCCCTTGCGGG

Product: tetraheme cytochrome c

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MNWRALFKPSAKYSIFALLLVGVVVGVVGYFATQTTLHMTSTDEFCMSCHSNHSLKDEVLASAHGNNKNGIVVQCQQCHI
AQEPFAYLKKKIIVSKDVIGFLTIDGFNTQEWLEANRKEQADLARDYLRSIDSSTCQNCHNRIYENQSENMSKMAVRMHS
NNFKKDPESRKTCIDCHKGVAHPYPKS

Sequences:

>Translated_187_residues
MNWRALFKPSAKYSIFALLLVGVVVGVVGYFATQTTLHMTSTDEFCMSCHSNHSLKDEVLASAHGNNKNGIVVQCQQCHI
AQEPFAYLKKKIIVSKDVIGFLTIDGFNTQEWLEANRKEQADLARDYLRSIDSSTCQNCHNRIYENQSENMSKMAVRMHS
NNFKKDPESRKTCIDCHKGVAHPYPKS
>Mature_187_residues
MNWRALFKPSAKYSIFALLLVGVVVGVVGYFATQTTLHMTSTDEFCMSCHSNHSLKDEVLASAHGNNKNGIVVQCQQCHI
AQEPFAYLKKKIIVSKDVIGFLTIDGFNTQEWLEANRKEQADLARDYLRSIDSSTCQNCHNRIYENQSENMSKMAVRMHS
NNFKKDPESRKTCIDCHKGVAHPYPKS

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=183, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788530, Length=186, Percent_Identity=33.8709677419355, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1788181, Length=169, Percent_Identity=37.8698224852071, Blast_Score=100, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 21191; Mature: 21191

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWRALFKPSAKYSIFALLLVGVVVGVVGYFATQTTLHMTSTDEFCMSCHSNHSLKDEVL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCCCCCHHHHHH
ASAHGNNKNGIVVQCQQCHIAQEPFAYLKKKIIVSKDVIGFLTIDGFNTQEWLEANRKEQ
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHH
ADLARDYLRSIDSSTCQNCHNRIYENQSENMSKMAVRMHSNNFKKDPESRKTCIDCHKGV
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
AHPYPKS
CCCCCCC
>Mature Secondary Structure
MNWRALFKPSAKYSIFALLLVGVVVGVVGYFATQTTLHMTSTDEFCMSCHSNHSLKDEVL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHCCCCCHHHHHH
ASAHGNNKNGIVVQCQQCHIAQEPFAYLKKKIIVSKDVIGFLTIDGFNTQEWLEANRKEQ
HHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCHHH
ADLARDYLRSIDSSTCQNCHNRIYENQSENMSKMAVRMHSNNFKKDPESRKTCIDCHKGV
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
AHPYPKS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]