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The map label for this gene is iorB [H]

Identifier: 119776571

GI number: 119776571

Start: 4069725

End: 4071977

Strand: Direct

Name: iorB [H]

Synonym: Sama_3439

Alternate gene names: 119776571

Gene position: 4069725-4071977 (Clockwise)

Preceding gene: 119776570

Following gene: 119776572

Centisome position: 94.51

GC content: 59.34

Gene sequence:

>2253_bases
ATGAGCAAGTTTACTGCCATTGAAAACTTCAGCCGCCGCGATGTGCTCAAACTCTTTGGTGCCTCGGGCGGCGCCCTGAT
GCTGGGGGCTTCGGGCCTCGGCTGGAGCCCCATGCTGGCGGCGCAAACCGCCGCTTTTGGCGATGAACAGCGGCTCAACC
TTTTCATCGCCATCGGCGAAGACAACCGGGTCTATCTCACCTGCCACCGCTCAGAGATGGGCCAGGGCATACGCACAGGT
ATTGTGCAGGTTCTGGCCGACGAGCTGGAAGCCGACTGGGACAAGGTCGTCGTAGTGCAAGGTCTCGCGGACAAACGCTA
CGGCAGCCAAAACACCGATGGCAGCCGCAGTATCCGCAAAGGCTTCGATAAGATGCGCGAGATGGGCGCCATGGCAAGAC
ACATGCTGGAGCAGGCTGCCGCCGAGAGCTGGCAGGTGCCTGTAAGCGAGGTCTATGCCAAGGCCCACGCAGTACATCAC
AAGGGCAGCGACAAACGCTTAAGCTATGGCGAGCTCGCCATGGCCGCCGCCAAACTGCCCATGCCGGATGCCAAAACCCT
TACCCTCAAAACCCCGGATAAGTTCACCCAAATCGGCAAAGGACACACCATTGTCGACATGGACGACATGCTGGGTGGCC
GCGCCATCTATGGCGCCGACAACCGCCCCGAGGGGCTGGTATACGCCGTCATAGCCCGTCCACCAGTGTTTGGCAGTCAG
CTTGAGTCCTTGGATGACAGCGCCGCCCGCAAGGTGGCGGGTGTGCTGGATATTGTCACCCTACCGGTACCCAAAGGCGC
ACCGGCGTTTCAGCCGCTGGGCGGCGTGGCCGTGGTGGCCAGCAATACCTGGAGTGCGTTGGAAGGCCGAAAAGCCCTCA
AGCTCAGTTGGAGTAAAAGTGCCAACGACACCCATAACAGCAAGGCTTATCTCGATACCCTCAAACAAAGGGTGCAGGAG
CCTGGTAAAGTGGCCCGAGAGCTTGGCAGCCAACCTGCCAGCTGGCCAGAGGACAAGATGGTCAGCGCCACATACACTGT
GCCCTATCTTGCCCACGCGCCCATGGAGCCACCGGCGGTGATTGCCAGCGTGGATAAAAATGGCTGTGAGCTGTGGGCCA
GCAGCCAAACGCCCCAAAGCACTCAACAGAATGTGGCTGGCATGCTGGGTATCGACGAAGACAAGGTGAAGGTAAACGTG
ACCTTGCTCGGCGGCGGTTTTGGTCGCAAGTCCAAGCCGGATTTCAGTGTCGAAGCCGCGTTTATTTCCAGCAAAATCAA
CAAACCTGTGCTGGTGCAATGGAGCCGGGAAGACGAACTCAGAAACGGTTATCTGCACGCCATCAGCGCCCAGTACTATC
AGGCCTGCATCGATGAAAAGGGCAAGGTGCAGGCGATGTTGTCGCGCACTGCCTTCCCCTCCATCGGCAGCACCTTCGAC
AGTGCTGTGGATACCCCGCAGCCGTTCGAACTGGACCTGGGCTTTACCGATATCCCCTGGGATATCAATGCCGTGCGCTG
CGAAGCCGTCAAGGCCGAAACCCACACCCGCATCGGTTGGTTAAGGTCGGTAAGCAACATTCAGCACGGCTTTGGGGTGG
GCAGCTTTGTGGACGAACTCGCCATTGCCAATGGTAAATCCTGCACCGCCCAATGGCGGGAACTACTCGGCAAGGCGCGG
GTTGAAAACTTTGCCAATCAAGGCTTTGAATATGGCAACTATGGTGAAGAGCAGAGCCGTCATCCGGTGGATGTGGGCCG
CTACCTTAAGCTGATTGACCGCGCCGAAGCGCTGACGGCACAAAAACCCGCCGGCAAAAACGAAGGTTGGGGCTTTGCCA
TTCACCGCAGCTTTGTTGCCTATGCCGCCGTGGCCATCAAGGTACGACTTGAAGGTGACAAACTCACCGTGGTGGACGCC
ATCGCCCTGATGGATGCGGGCACCGTGGTTAACCCCGACCGGGTGGCCGCCCAGATGGAAGGCGCAGTCGTGTTTGGCTT
AAGCCTTGCGCTCTTTGGTGAAATCGATTTCGACCAGGGCGCCGTGACCCAGTCAAACTTCCATGACTACCCGCTGCTCA
GGCTGCCACATTGCCCGCCAATTGCCACCGAAATCATCGCCTCCAGCGCCGTGCCCGGCGGCGTGGGTGAGCCCGGCGTG
CCACCGGTCGCCCCGGCACTGACCAACGCCATTGTGGCAGCCGGTGGCAAACGGTATCGTGAACTGCCGCTGTCGAAGCA
CCTTAAACTCTAA

Upstream 100 bases:

>100_bases
AGATTGACGAGGCCATGGCAGGCAACATCTGCCGCTGCGGCACCTACACCCGTATACGCGCCGCCATCAAGGACTATCAG
GGCAAGCAGGAGGCCAAGTC

Downstream 100 bases:

>100_bases
CCTACTGCCGTTTAATCCAGGCTCCCAGTCATACTGGGGGCCTGTTTTTTTGGGCGCAGCCACCCGGCTTTGTTATACTC
CAGCCCAACTCAGATCTGAT

Product: isoquinoline 1-oxidoreductase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 750; Mature: 749

Protein sequence:

>750_residues
MSKFTAIENFSRRDVLKLFGASGGALMLGASGLGWSPMLAAQTAAFGDEQRLNLFIAIGEDNRVYLTCHRSEMGQGIRTG
IVQVLADELEADWDKVVVVQGLADKRYGSQNTDGSRSIRKGFDKMREMGAMARHMLEQAAAESWQVPVSEVYAKAHAVHH
KGSDKRLSYGELAMAAAKLPMPDAKTLTLKTPDKFTQIGKGHTIVDMDDMLGGRAIYGADNRPEGLVYAVIARPPVFGSQ
LESLDDSAARKVAGVLDIVTLPVPKGAPAFQPLGGVAVVASNTWSALEGRKALKLSWSKSANDTHNSKAYLDTLKQRVQE
PGKVARELGSQPASWPEDKMVSATYTVPYLAHAPMEPPAVIASVDKNGCELWASSQTPQSTQQNVAGMLGIDEDKVKVNV
TLLGGGFGRKSKPDFSVEAAFISSKINKPVLVQWSREDELRNGYLHAISAQYYQACIDEKGKVQAMLSRTAFPSIGSTFD
SAVDTPQPFELDLGFTDIPWDINAVRCEAVKAETHTRIGWLRSVSNIQHGFGVGSFVDELAIANGKSCTAQWRELLGKAR
VENFANQGFEYGNYGEEQSRHPVDVGRYLKLIDRAEALTAQKPAGKNEGWGFAIHRSFVAYAAVAIKVRLEGDKLTVVDA
IALMDAGTVVNPDRVAAQMEGAVVFGLSLALFGEIDFDQGAVTQSNFHDYPLLRLPHCPPIATEIIASSAVPGGVGEPGV
PPVAPALTNAIVAAGGKRYRELPLSKHLKL

Sequences:

>Translated_750_residues
MSKFTAIENFSRRDVLKLFGASGGALMLGASGLGWSPMLAAQTAAFGDEQRLNLFIAIGEDNRVYLTCHRSEMGQGIRTG
IVQVLADELEADWDKVVVVQGLADKRYGSQNTDGSRSIRKGFDKMREMGAMARHMLEQAAAESWQVPVSEVYAKAHAVHH
KGSDKRLSYGELAMAAAKLPMPDAKTLTLKTPDKFTQIGKGHTIVDMDDMLGGRAIYGADNRPEGLVYAVIARPPVFGSQ
LESLDDSAARKVAGVLDIVTLPVPKGAPAFQPLGGVAVVASNTWSALEGRKALKLSWSKSANDTHNSKAYLDTLKQRVQE
PGKVARELGSQPASWPEDKMVSATYTVPYLAHAPMEPPAVIASVDKNGCELWASSQTPQSTQQNVAGMLGIDEDKVKVNV
TLLGGGFGRKSKPDFSVEAAFISSKINKPVLVQWSREDELRNGYLHAISAQYYQACIDEKGKVQAMLSRTAFPSIGSTFD
SAVDTPQPFELDLGFTDIPWDINAVRCEAVKAETHTRIGWLRSVSNIQHGFGVGSFVDELAIANGKSCTAQWRELLGKAR
VENFANQGFEYGNYGEEQSRHPVDVGRYLKLIDRAEALTAQKPAGKNEGWGFAIHRSFVAYAAVAIKVRLEGDKLTVVDA
IALMDAGTVVNPDRVAAQMEGAVVFGLSLALFGEIDFDQGAVTQSNFHDYPLLRLPHCPPIATEIIASSAVPGGVGEPGV
PPVAPALTNAIVAAGGKRYRELPLSKHLKL
>Mature_749_residues
SKFTAIENFSRRDVLKLFGASGGALMLGASGLGWSPMLAAQTAAFGDEQRLNLFIAIGEDNRVYLTCHRSEMGQGIRTGI
VQVLADELEADWDKVVVVQGLADKRYGSQNTDGSRSIRKGFDKMREMGAMARHMLEQAAAESWQVPVSEVYAKAHAVHHK
GSDKRLSYGELAMAAAKLPMPDAKTLTLKTPDKFTQIGKGHTIVDMDDMLGGRAIYGADNRPEGLVYAVIARPPVFGSQL
ESLDDSAARKVAGVLDIVTLPVPKGAPAFQPLGGVAVVASNTWSALEGRKALKLSWSKSANDTHNSKAYLDTLKQRVQEP
GKVARELGSQPASWPEDKMVSATYTVPYLAHAPMEPPAVIASVDKNGCELWASSQTPQSTQQNVAGMLGIDEDKVKVNVT
LLGGGFGRKSKPDFSVEAAFISSKINKPVLVQWSREDELRNGYLHAISAQYYQACIDEKGKVQAMLSRTAFPSIGSTFDS
AVDTPQPFELDLGFTDIPWDINAVRCEAVKAETHTRIGWLRSVSNIQHGFGVGSFVDELAIANGKSCTAQWRELLGKARV
ENFANQGFEYGNYGEEQSRHPVDVGRYLKLIDRAEALTAQKPAGKNEGWGFAIHRSFVAYAAVAIKVRLEGDKLTVVDAI
ALMDAGTVVNPDRVAAQMEGAVVFGLSLALFGEIDFDQGAVTQSNFHDYPLLRLPHCPPIATEIIASSAVPGGVGEPGVP
PVAPALTNAIVAAGGKRYRELPLSKHLKL

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 80871; Mature: 80740

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFTAIENFSRRDVLKLFGASGGALMLGASGLGWSPMLAAQTAAFGDEQRLNLFIAIGE
CCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEECC
DNRVYLTCHRSEMGQGIRTGIVQVLADELEADWDKVVVVQGLADKRYGSQNTDGSRSIRK
CCEEEEEEECHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHH
GFDKMREMGAMARHMLEQAAAESWQVPVSEVYAKAHAVHHKGSDKRLSYGELAMAAAKLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
MPDAKTLTLKTPDKFTQIGKGHTIVDMDDMLGGRAIYGADNRPEGLVYAVIARPPVFGSQ
CCCCCEEEEECCHHHHHCCCCCEEEEHHHHCCCEEEECCCCCCCCEEEEEEECCCCCHHH
LESLDDSAARKVAGVLDIVTLPVPKGAPAFQPLGGVAVVASNTWSALEGRKALKLSWSKS
HHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCHHHHCCCCEEEEEECCC
ANDTHNSKAYLDTLKQRVQEPGKVARELGSQPASWPEDKMVSATYTVPYLAHAPMEPPAV
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEE
IASVDKNGCELWASSQTPQSTQQNVAGMLGIDEDKVKVNVTLLGGGFGRKSKPDFSVEAA
EEECCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEHH
FISSKINKPVLVQWSREDELRNGYLHAISAQYYQACIDEKGKVQAMLSRTAFPSIGSTFD
HHHHHCCCCEEEEECCCHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
SAVDTPQPFELDLGFTDIPWDINAVRCEAVKAETHTRIGWLRSVSNIQHGFGVGSFVDEL
HHCCCCCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIANGKSCTAQWRELLGKARVENFANQGFEYGNYGEEQSRHPVDVGRYLKLIDRAEALTA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QKPAGKNEGWGFAIHRSFVAYAAVAIKVRLEGDKLTVVDAIALMDAGTVVNPDRVAAQME
CCCCCCCCCCEEHHHHHHHHHEEEEEEEEECCCEEEEHHHHHHHCCCCCCCHHHHHHHHC
GAVVFGLSLALFGEIDFDQGAVTQSNFHDYPLLRLPHCPPIATEIIASSAVPGGVGEPGV
CEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCC
PPVAPALTNAIVAAGGKRYRELPLSKHLKL
CCCHHHHHHHHHHCCCHHHHHCCCHHCCCC
>Mature Secondary Structure 
SKFTAIENFSRRDVLKLFGASGGALMLGASGLGWSPMLAAQTAAFGDEQRLNLFIAIGE
CCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEEECC
DNRVYLTCHRSEMGQGIRTGIVQVLADELEADWDKVVVVQGLADKRYGSQNTDGSRSIRK
CCEEEEEEECHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCHHHHHH
GFDKMREMGAMARHMLEQAAAESWQVPVSEVYAKAHAVHHKGSDKRLSYGELAMAAAKLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
MPDAKTLTLKTPDKFTQIGKGHTIVDMDDMLGGRAIYGADNRPEGLVYAVIARPPVFGSQ
CCCCCEEEEECCHHHHHCCCCCEEEEHHHHCCCEEEECCCCCCCCEEEEEEECCCCCHHH
LESLDDSAARKVAGVLDIVTLPVPKGAPAFQPLGGVAVVASNTWSALEGRKALKLSWSKS
HHHCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECCCHHHHCCCCEEEEEECCC
ANDTHNSKAYLDTLKQRVQEPGKVARELGSQPASWPEDKMVSATYTVPYLAHAPMEPPAV
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEE
IASVDKNGCELWASSQTPQSTQQNVAGMLGIDEDKVKVNVTLLGGGFGRKSKPDFSVEAA
EEECCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEHH
FISSKINKPVLVQWSREDELRNGYLHAISAQYYQACIDEKGKVQAMLSRTAFPSIGSTFD
HHHHHCCCCEEEEECCCHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
SAVDTPQPFELDLGFTDIPWDINAVRCEAVKAETHTRIGWLRSVSNIQHGFGVGSFVDEL
HHCCCCCCEEEECCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIANGKSCTAQWRELLGKARVENFANQGFEYGNYGEEQSRHPVDVGRYLKLIDRAEALTA
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
QKPAGKNEGWGFAIHRSFVAYAAVAIKVRLEGDKLTVVDAIALMDAGTVVNPDRVAAQME
CCCCCCCCCCEEHHHHHHHHHEEEEEEEEECCCEEEEHHHHHHHCCCCCCCHHHHHHHHC
GAVVFGLSLALFGEIDFDQGAVTQSNFHDYPLLRLPHCPPIATEIIASSAVPGGVGEPGV
CEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCC
PPVAPALTNAIVAAGGKRYRELPLSKHLKL
CCCHHHHHHHHHHCCCHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]