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The map label for this gene is 119776240

Identifier: 119776240

GI number: 119776240

Start: 3679771

End: 3681912

Strand: Reverse

Name: 119776240

Synonym: Sama_3108

Alternate gene names: NA

Gene position: 3681912-3679771 (Counterclockwise)

Preceding gene: 119776241

Following gene: 119776239

Centisome position: 85.5

GC content: 56.58

Gene sequence:

>2142_bases
ATGGGTCATCCATTAACGCAAATGTTTCGTACCATGTGTCTGGGATCTGCCCTTGTTGGGCTGATTTGGATTAGCCCTGT
TGCCGATGCGGCCGGGCTGTTGAAACCCGTCGGCAGTCAATACCGAGATATGCAAATTCAATCCCATCATGTGGAGGTGG
TTATCCAGGATGGCCATGCCACCACCGCCATCGAACAAACTTTTTATAACCCCAACCCCGATACACTGGAGGCGCTCTAC
TCCTTCCCGGTGCCACAGCAAGCCGTGGTCGGCGAGTTTATCTATTGGATTAATGATGTGCCTGTGGTTGCCGAAGCTGT
GCCCCGGCAAAAGGCCCGCGAGATTTACGAGGACCAGAAAGCACAGGGCAATGCCACAGCTCTGACTGAAAAGGACGACT
ACAAGCGCTTTGATATGCGGGTATTTCCGGTGCAGCCGCAACAGTCGGTAAAGGTTCGGCTGGTGTATATGCAGGATGCC
TTGCTGGACCACGGCGTTGGCCGTTATCTCTACCCTTTGGAGGAGGGCGGTGTGGATGAGGCCCGGGACAGCTTTTGGCA
GCGCAATGCCGTGGTCGAACAGGACTTCTCCTTTAATGTCACCCTGCGCTCGGCTTATCCGGTGGACGGTGTGAGGTTGC
CGTCCCATCCGGAGGCTGAGATACATCAGGAGATGCAGGCAGGCGCTGCTCTGTGGCGCGCCAGCCTGACGAGTCAGCCT
GAGAGCCTCCATACTGGCGCCATTGAAAGCGTGAGTGCTAATGAAGATACCAGTCAGGGTGCGGAAAGTGGTGCTGCAGG
GGAAGGGAAGGCTTCGCATCAGCCCAGGGCCATGGGGCTCGATAAGGACATCGTTTTTTACTGGCGTCTGCAGGAAGGTT
TGCCGGGCCGGGTGGACATGGTGACCTATCGCGATCCCAAAGTCTCGACCAAGGGCACGGTAAAGCTGACCTTTACACCC
GGTGATGATTTAGGGCCCGTGACTCAGGGCCGGGACTGGGTGTTTGTGCTGGATAAGTCCGGCTCCATGAATGGCAAGTA
TGCCACCCTGGTGGAAGGTGTGCGCCAGGGGCTGGGTAAACTGCCAGCGCAGGACAGATTCAGGATCATTCTGTTCGATG
AAAGCACTCAGGAATTCAGCAAGGGCTTTGTGCCGGTTGACAGCAACAACATCAACCAAGCGCTGGCCTGGGTTGAGGGC
ATCAGCCCCGGAAATGGCACCGATCTGTATCAGGGGCTGAAGCGTGCTCTGACTCCACTGGATGCCGACCGTTCCACAGG
GGTGGTGTTGATAACCGATGGGGTGGCGAATGTGGGCGTGACTGAAAAACGGCGCTTCTTAGAGTTGATGCAGCAACAGG
ATGTTCGCCTGTTCACCTTCATCATGGGCAACAGTGCCAATACGCCCCTGTTGGTACCCATGACCCGCTTGTCCAACGGT
GTGGCAACCTCAGTCTCCAACGCCGATGATATCGTGGGTCATCTGATGAATATCACCAGCAAGCTGACTCATCAGGCCTA
TCGCAATATTCGCCTCGATATGGATGGTGTGAAGATTAACGATCTGACCCCGCAGGAGATAGCGAGTCTATATCGGGGCG
AGCAATTGGTGCTGTTCGGCCATTATTTTGCTGCCGGTGAGGCCAAACTCACCCTCACCATGGACATAGGCGCAGAGTCC
CGCGAATACAGCACCAAGGTGATGCTGCCTGAGGCTGCTCTGGACTACCCAGAACTTGAGCGGATGTGGGCGTTCTCTGC
CATTAACGGTCTGCAGGAACAGATGGACTACCTGGAGCAAAAAGACAGCGACAAGGAAAAAGCCATTGAGGACATCGCCA
TCGAGTATGGGCTGCTGACCGACTACACCTCCTTGCTGGTGGTAGAAGAGGATGTCTTCCGTCAACTCGGTATCGAGCGG
GATAATCGGCGCCGGGTCAGTACAGAGCAGGCTGCGCGCAAAACAAGGGAAACGCAACCCCCGGCACCAACCCGCGCCGA
CAAGCACCAGCCCATGTTCTCGCAGCCTCAGCCAACCCACTCTGGCGGTGGCGGAGGCGGAGGCAGTATGGGCCTGTGGA
CGCTGCTGGTCCTCTTGCTGCTGGGCAGAGTGCGGCTTGTGGACGTTAGGCCAAGCCGTTAA

Upstream 100 bases:

>100_bases
ATGCCACTCTCGTCATCTCACTTTTTTGCTTTTGCCTCTGAGTGCAAGCTCCTTTTCGGGAGTGACGGTCACTCTCTTCC
TCAGGACGAAGGAGGCAAAA

Downstream 100 bases:

>100_bases
GCTTCGAGGCTGCACTCACTGACGAGGGCAGCCTTGTTTTTAGGCTTGGGATGGGTCGAACACGGCTTGGAGTGGCGATG
TGGGAGGGGGGTTAGTGTTG

Product: von Willebrand factor type A (vWA) domain-containing protein

Products: NA

Alternate protein names: Von Willebrand Factor Type A Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin; Vault Protein Inter-Alpha-Trypsin Domain Protein; Cell Wall Anchor Domain-Containing Protein; Inter-Alpha-Trypsin Inhibitor Domain-Containing Protein; Von Willebrand Factor Type A; Vault Protein Inter-Alpha-Trypsin Domain-Containing Protein; LPXTG-Motif Cell Wall Anchor Domain-Containing Protein; Transmembrane Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; Vault Protein Inter-Alpha-Trypsin Domain; Protein ContAining A Von Willebrand Factor Type A Domain; Inter-Alpha-Trypsin Inhibitor Domain Protein; Von Willebrand Factor; Von Willebrand Factor Type A Domain Protein

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MGHPLTQMFRTMCLGSALVGLIWISPVADAAGLLKPVGSQYRDMQIQSHHVEVVIQDGHATTAIEQTFYNPNPDTLEALY
SFPVPQQAVVGEFIYWINDVPVVAEAVPRQKAREIYEDQKAQGNATALTEKDDYKRFDMRVFPVQPQQSVKVRLVYMQDA
LLDHGVGRYLYPLEEGGVDEARDSFWQRNAVVEQDFSFNVTLRSAYPVDGVRLPSHPEAEIHQEMQAGAALWRASLTSQP
ESLHTGAIESVSANEDTSQGAESGAAGEGKASHQPRAMGLDKDIVFYWRLQEGLPGRVDMVTYRDPKVSTKGTVKLTFTP
GDDLGPVTQGRDWVFVLDKSGSMNGKYATLVEGVRQGLGKLPAQDRFRIILFDESTQEFSKGFVPVDSNNINQALAWVEG
ISPGNGTDLYQGLKRALTPLDADRSTGVVLITDGVANVGVTEKRRFLELMQQQDVRLFTFIMGNSANTPLLVPMTRLSNG
VATSVSNADDIVGHLMNITSKLTHQAYRNIRLDMDGVKINDLTPQEIASLYRGEQLVLFGHYFAAGEAKLTLTMDIGAES
REYSTKVMLPEAALDYPELERMWAFSAINGLQEQMDYLEQKDSDKEKAIEDIAIEYGLLTDYTSLLVVEEDVFRQLGIER
DNRRRVSTEQAARKTRETQPPAPTRADKHQPMFSQPQPTHSGGGGGGGSMGLWTLLVLLLLGRVRLVDVRPSR

Sequences:

>Translated_713_residues
MGHPLTQMFRTMCLGSALVGLIWISPVADAAGLLKPVGSQYRDMQIQSHHVEVVIQDGHATTAIEQTFYNPNPDTLEALY
SFPVPQQAVVGEFIYWINDVPVVAEAVPRQKAREIYEDQKAQGNATALTEKDDYKRFDMRVFPVQPQQSVKVRLVYMQDA
LLDHGVGRYLYPLEEGGVDEARDSFWQRNAVVEQDFSFNVTLRSAYPVDGVRLPSHPEAEIHQEMQAGAALWRASLTSQP
ESLHTGAIESVSANEDTSQGAESGAAGEGKASHQPRAMGLDKDIVFYWRLQEGLPGRVDMVTYRDPKVSTKGTVKLTFTP
GDDLGPVTQGRDWVFVLDKSGSMNGKYATLVEGVRQGLGKLPAQDRFRIILFDESTQEFSKGFVPVDSNNINQALAWVEG
ISPGNGTDLYQGLKRALTPLDADRSTGVVLITDGVANVGVTEKRRFLELMQQQDVRLFTFIMGNSANTPLLVPMTRLSNG
VATSVSNADDIVGHLMNITSKLTHQAYRNIRLDMDGVKINDLTPQEIASLYRGEQLVLFGHYFAAGEAKLTLTMDIGAES
REYSTKVMLPEAALDYPELERMWAFSAINGLQEQMDYLEQKDSDKEKAIEDIAIEYGLLTDYTSLLVVEEDVFRQLGIER
DNRRRVSTEQAARKTRETQPPAPTRADKHQPMFSQPQPTHSGGGGGGGSMGLWTLLVLLLLGRVRLVDVRPSR
>Mature_712_residues
GHPLTQMFRTMCLGSALVGLIWISPVADAAGLLKPVGSQYRDMQIQSHHVEVVIQDGHATTAIEQTFYNPNPDTLEALYS
FPVPQQAVVGEFIYWINDVPVVAEAVPRQKAREIYEDQKAQGNATALTEKDDYKRFDMRVFPVQPQQSVKVRLVYMQDAL
LDHGVGRYLYPLEEGGVDEARDSFWQRNAVVEQDFSFNVTLRSAYPVDGVRLPSHPEAEIHQEMQAGAALWRASLTSQPE
SLHTGAIESVSANEDTSQGAESGAAGEGKASHQPRAMGLDKDIVFYWRLQEGLPGRVDMVTYRDPKVSTKGTVKLTFTPG
DDLGPVTQGRDWVFVLDKSGSMNGKYATLVEGVRQGLGKLPAQDRFRIILFDESTQEFSKGFVPVDSNNINQALAWVEGI
SPGNGTDLYQGLKRALTPLDADRSTGVVLITDGVANVGVTEKRRFLELMQQQDVRLFTFIMGNSANTPLLVPMTRLSNGV
ATSVSNADDIVGHLMNITSKLTHQAYRNIRLDMDGVKINDLTPQEIASLYRGEQLVLFGHYFAAGEAKLTLTMDIGAESR
EYSTKVMLPEAALDYPELERMWAFSAINGLQEQMDYLEQKDSDKEKAIEDIAIEYGLLTDYTSLLVVEEDVFRQLGIERD
NRRRVSTEQAARKTRETQPPAPTRADKHQPMFSQPQPTHSGGGGGGGSMGLWTLLVLLLLGRVRLVDVRPSR

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI70778918, Length=617, Percent_Identity=18.8006482982172, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI31542984, Length=338, Percent_Identity=23.9644970414201, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI262050538, Length=338, Percent_Identity=23.9644970414201, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI261878618, Length=378, Percent_Identity=21.957671957672, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI261878616, Length=378, Percent_Identity=21.957671957672, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI261878614, Length=378, Percent_Identity=21.957671957672, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI156119625, Length=378, Percent_Identity=21.957671957672, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI153945780, Length=342, Percent_Identity=24.2690058479532, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI153945711, Length=342, Percent_Identity=24.2690058479532, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI49355778, Length=342, Percent_Identity=24.2690058479532, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI133925809, Length=332, Percent_Identity=25.3012048192771, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 79038; Mature: 78907

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHPLTQMFRTMCLGSALVGLIWISPVADAAGLLKPVGSQYRDMQIQSHHVEVVIQDGHA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEECCEEEEEEECCCC
TTAIEQTFYNPNPDTLEALYSFPVPQQAVVGEFIYWINDVPVVAEAVPRQKAREIYEDQK
CHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHC
AQGNATALTEKDDYKRFDMRVFPVQPQQSVKVRLVYMQDALLDHGVGRYLYPLEEGGVDE
CCCCCEEECCCCCCCEECEEEECCCCCCCCEEEEEEEHHHHHHCCCCCEEEECCCCCCCH
ARDSFWQRNAVVEQDFSFNVTLRSAYPVDGVRLPSHPEAEIHQEMQAGAALWRASLTSQP
HHHHHHHHCCCEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
ESLHTGAIESVSANEDTSQGAESGAAGEGKASHQPRAMGLDKDIVFYWRLQEGLPGRVDM
CHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEE
VTYRDPKVSTKGTVKLTFTPGDDLGPVTQGRDWVFVLDKSGSMNGKYATLVEGVRQGLGK
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHC
LPAQDRFRIILFDESTQEFSKGFVPVDSNNINQALAWVEGISPGNGTDLYQGLKRALTPL
CCCCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DADRSTGVVLITDGVANVGVTEKRRFLELMQQQDVRLFTFIMGNSANTPLLVPMTRLSNG
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEHHHCCCC
VATSVSNADDIVGHLMNITSKLTHQAYRNIRLDMDGVKINDLTPQEIASLYRGEQLVLFG
CEECCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEECCCCHHHHHHHHCCCEEEEEE
HYFAAGEAKLTLTMDIGAESREYSTKVMLPEAALDYPELERMWAFSAINGLQEQMDYLEQ
EEEECCCEEEEEEEECCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDSDKEKAIEDIAIEYGLLTDYTSLLVVEEDVFRQLGIERDNRRRVSTEQAARKTRETQP
CCCCHHHHHHHHHHHHHHHHCCHHHEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
PAPTRADKHQPMFSQPQPTHSGGGGGGGSMGLWTLLVLLLLGRVRLVDVRPSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC
>Mature Secondary Structure 
GHPLTQMFRTMCLGSALVGLIWISPVADAAGLLKPVGSQYRDMQIQSHHVEVVIQDGHA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEECCEEEEEEECCCC
TTAIEQTFYNPNPDTLEALYSFPVPQQAVVGEFIYWINDVPVVAEAVPRQKAREIYEDQK
CHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHC
AQGNATALTEKDDYKRFDMRVFPVQPQQSVKVRLVYMQDALLDHGVGRYLYPLEEGGVDE
CCCCCEEECCCCCCCEECEEEECCCCCCCCEEEEEEEHHHHHHCCCCCEEEECCCCCCCH
ARDSFWQRNAVVEQDFSFNVTLRSAYPVDGVRLPSHPEAEIHQEMQAGAALWRASLTSQP
HHHHHHHHCCCEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
ESLHTGAIESVSANEDTSQGAESGAAGEGKASHQPRAMGLDKDIVFYWRLQEGLPGRVDM
CHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEE
VTYRDPKVSTKGTVKLTFTPGDDLGPVTQGRDWVFVLDKSGSMNGKYATLVEGVRQGLGK
EEECCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHC
LPAQDRFRIILFDESTQEFSKGFVPVDSNNINQALAWVEGISPGNGTDLYQGLKRALTPL
CCCCCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DADRSTGVVLITDGVANVGVTEKRRFLELMQQQDVRLFTFIMGNSANTPLLVPMTRLSNG
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEHHHCCCC
VATSVSNADDIVGHLMNITSKLTHQAYRNIRLDMDGVKINDLTPQEIASLYRGEQLVLFG
CEECCCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEECCCCHHHHHHHHCCCEEEEEE
HYFAAGEAKLTLTMDIGAESREYSTKVMLPEAALDYPELERMWAFSAINGLQEQMDYLEQ
EEEECCCEEEEEEEECCCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDSDKEKAIEDIAIEYGLLTDYTSLLVVEEDVFRQLGIERDNRRRVSTEQAARKTRETQP
CCCCHHHHHHHHHHHHHHHHCCHHHEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCC
PAPTRADKHQPMFSQPQPTHSGGGGGGGSMGLWTLLVLLLLGRVRLVDVRPSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA