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The map label for this gene is murA

Identifier: 119776207

GI number: 119776207

Start: 3654274

End: 3655530

Strand: Reverse

Name: murA

Synonym: Sama_3075

Alternate gene names: 119776207

Gene position: 3655530-3654274 (Counterclockwise)

Preceding gene: 119776208

Following gene: 119776204

Centisome position: 84.89

GC content: 56.09

Gene sequence:

>1257_bases
GTGGATAAGCTTTCTATTCAGTCCGGCGGTCCTCTTGCCGGGACTGTGGTTATTTCCGGTGCCAAAAATGCCGCGCTGCC
CATTTTGATGGCAGGGGTACTGGCCGAGTCCCCATTTGTATTGACCAATGTACCAAGCCTGCGCGACGTGGATACCAGCT
GTAAGCTGCTGCGTTGCCTGGGGGCTGAAGTCACTCAGGATGGCGATCGCATCACCATTGATTCGTCGCGTATCGATCAT
TTCGTTGCGCCTTACGAGTTGGTGAAAACCATGCGCGCTTCAATTTTGATTTTGGGACCTCTGCTCGCCCGCTTCGGCAC
TGCTGATGTGTCTCTGCCGGGTGGCTGCGCCATTGGTGCCCGCCCCGTAAACCTGCACCTGCACGGCCTGGAGCAGATGG
GTGCCAAAATCGAGGTGAAGGAAGGTTATATCAAGGCCCGGGTAGACGGTCGTCTCAAGGGCGCCCATATCTTTATGGAT
ATGGTAAGCGTAGGTGCTACCGAAAACTTGCTCATGGCTGCAGCGCTGGCTGATGGCGTCACCGTGATTGAAAACGCGGC
CCGAGAGCCTGAGGTTATCGACCTTGCCAATTGTCTGGTTGCCATGGGCGCTCAAATCAGCGGTATAGGCACCGCCACGT
TGAAAATTACCGGCGTTGAGCGTTTGAATGGATGTGATTACCGCGTGATGCCGGATCGTATCGAAACCGGTACTTTCCTG
GTGGCCGCCGCCGTGACCCGTGGTCGCATCCGCTGCGAAAATGCCGACCCATCTTCTCTGGAGTCAGTGCTCGCCAAGCT
CGAAGATGCCGGCGCCGAAATCAACACCGGCGACGATTGGATTGAGCTGGACATGCATGGAAAGCGCCCCAAAGCGGTAA
ACATCAAAACCGCACCTTATCCGGCGTTTCCCACCGACATGCAGGCTCAGTTTTGTGTGCTCAACTGTTTGGCCGAAGGT
ACTGGCACAATCACAGAGACTATCTTCGAAAACCGCTTTATGCACGTGCCTGAGCTGATGCGTATGGGCGCCAACATGGA
GCTGGAAGGTCACACCTGCATAGTACACGGTGTTGAGCGCTTGAGCGGTGCCCAGGTCATGGCCACCGATTTGCGTGCCT
CTGCGAGCCTGGTGATTGCTGGTTTGATGGCCGACGGTACTACGCTGGTGGACCGTATCTATCACCTCGACCGTGGCTAC
GAACACATTGAGACCAAGTTCGAAGGCCTCGGTGGCAAGGTCGTTCGGGTGAAGTAA

Upstream 100 bases:

>100_bases
CCAGTGGTGCCCTGCATGCACTCAGCATCAAAACTTTCACGCCAACCCAATGGAAGCGTGAAAAAATCTTCAACATGCCG
CTCTAAGCAAGAGAGATATC

Downstream 100 bases:

>100_bases
ACTGCATCTCTAAGCAATAAAAACCGCCTTGACCGGCGGTTTTTTGTTATATGATGGTTGCATATTTGTTTTTGGTCGGA
GTCAGGGAAATGATGAAAAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDKLSIQSGGPLAGTVVISGAKNAALPILMAGVLAESPFVLTNVPSLRDVDTSCKLLRCLGAEVTQDGDRITIDSSRIDH
FVAPYELVKTMRASILILGPLLARFGTADVSLPGGCAIGARPVNLHLHGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMD
MVSVGATENLLMAAALADGVTVIENAAREPEVIDLANCLVAMGAQISGIGTATLKITGVERLNGCDYRVMPDRIETGTFL
VAAAVTRGRIRCENADPSSLESVLAKLEDAGAEINTGDDWIELDMHGKRPKAVNIKTAPYPAFPTDMQAQFCVLNCLAEG
TGTITETIFENRFMHVPELMRMGANMELEGHTCIVHGVERLSGAQVMATDLRASASLVIAGLMADGTTLVDRIYHLDRGY
EHIETKFEGLGGKVVRVK

Sequences:

>Translated_418_residues
MDKLSIQSGGPLAGTVVISGAKNAALPILMAGVLAESPFVLTNVPSLRDVDTSCKLLRCLGAEVTQDGDRITIDSSRIDH
FVAPYELVKTMRASILILGPLLARFGTADVSLPGGCAIGARPVNLHLHGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMD
MVSVGATENLLMAAALADGVTVIENAAREPEVIDLANCLVAMGAQISGIGTATLKITGVERLNGCDYRVMPDRIETGTFL
VAAAVTRGRIRCENADPSSLESVLAKLEDAGAEINTGDDWIELDMHGKRPKAVNIKTAPYPAFPTDMQAQFCVLNCLAEG
TGTITETIFENRFMHVPELMRMGANMELEGHTCIVHGVERLSGAQVMATDLRASASLVIAGLMADGTTLVDRIYHLDRGY
EHIETKFEGLGGKVVRVK
>Mature_418_residues
MDKLSIQSGGPLAGTVVISGAKNAALPILMAGVLAESPFVLTNVPSLRDVDTSCKLLRCLGAEVTQDGDRITIDSSRIDH
FVAPYELVKTMRASILILGPLLARFGTADVSLPGGCAIGARPVNLHLHGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMD
MVSVGATENLLMAAALADGVTVIENAAREPEVIDLANCLVAMGAQISGIGTATLKITGVERLNGCDYRVMPDRIETGTFL
VAAAVTRGRIRCENADPSSLESVLAKLEDAGAEINTGDDWIELDMHGKRPKAVNIKTAPYPAFPTDMQAQFCVLNCLAEG
TGTITETIFENRFMHVPELMRMGANMELEGHTCIVHGVERLSGAQVMATDLRASASLVIAGLMADGTTLVDRIYHLDRGY
EHIETKFEGLGGKVVRVK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=67.9425837320574, Blast_Score=582, Evalue=1e-167,
Organism=Escherichia coli, GI1787137, Length=425, Percent_Identity=26.1176470588235, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_SHEAM (A1SA71)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928947.1
- ProteinModelPortal:   A1SA71
- SMR:   A1SA71
- STRING:   A1SA71
- GeneID:   4605322
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3075
- NMPDR:   fig|326297.7.peg.2892
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   A1SA71
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44577; Mature: 44577

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLSIQSGGPLAGTVVISGAKNAALPILMAGVLAESPFVLTNVPSLRDVDTSCKLLRCL
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
GAEVTQDGDRITIDSSRIDHFVAPYELVKTMRASILILGPLLARFGTADVSLPGGCAIGA
CCHHCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
RPVNLHLHGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADGV
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCH
TVIENAAREPEVIDLANCLVAMGAQISGIGTATLKITGVERLNGCDYRVMPDRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCCCEEECCCCCCCCCEE
VAAAVTRGRIRCENADPSSLESVLAKLEDAGAEINTGDDWIELDMHGKRPKAVNIKTAPY
EEEEHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEECCCC
PAFPTDMQAQFCVLNCLAEGTGTITETIFENRFMHVPELMRMGANMELEGHTCIVHGVER
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHCCCCEEECCCEEEEEEHHH
LSGAQVMATDLRASASLVIAGLMADGTTLVDRIYHLDRGYEHIETKFEGLGGKVVRVK
HCCCEEEEHHHHCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MDKLSIQSGGPLAGTVVISGAKNAALPILMAGVLAESPFVLTNVPSLRDVDTSCKLLRCL
CCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHH
GAEVTQDGDRITIDSSRIDHFVAPYELVKTMRASILILGPLLARFGTADVSLPGGCAIGA
CCHHCCCCCEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
RPVNLHLHGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMDMVSVGATENLLMAAALADGV
EEEEEEEECHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCH
TVIENAAREPEVIDLANCLVAMGAQISGIGTATLKITGVERLNGCDYRVMPDRIETGTFL
HHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCCCEEECCCCCCCCCEE
VAAAVTRGRIRCENADPSSLESVLAKLEDAGAEINTGDDWIELDMHGKRPKAVNIKTAPY
EEEEHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEECCCC
PAFPTDMQAQFCVLNCLAEGTGTITETIFENRFMHVPELMRMGANMELEGHTCIVHGVER
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHCCCCEEECCCEEEEEEHHH
LSGAQVMATDLRASASLVIAGLMADGTTLVDRIYHLDRGYEHIETKFEGLGGKVVRVK
HCCCEEEEHHHHCCCEEEEEEHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA