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The map label for this gene is alr

Identifier: 119776189

GI number: 119776189

Start: 3632624

End: 3633718

Strand: Reverse

Name: alr

Synonym: Sama_3057

Alternate gene names: 119776189

Gene position: 3633718-3632624 (Counterclockwise)

Preceding gene: 119776190

Following gene: 119776187

Centisome position: 84.38

GC content: 56.62

Gene sequence:

>1095_bases
TTGAAACCTTTTCCCCGCGCAGAAATCAGCAGTCGCGCGCTGAAGGCCAACCTTAAAAGGCTGCGCCAAATTGCCCCGGG
CAGCAAGGTCATGGCCGTGGTGAAAGCCAACGGTTACGGTCATGGGCTGCTCAATGTGGCCGAGGTGCTAACCGATGCCC
ATTCAAATGCTGACGCAGATGGCTTCGGACTGGCAAGGCTTGAGGAAGCTCTGGAGGTCAGGGCCGGTGGTGTGTCTGCC
AGACTCTTATTACTGGAAGGCTTTTTCCGCAGTGAAGATTTGCCCCTGTTGGTGGAGCATGACATAGATACGGTCGTTCA
CCATGTCTCCCAGCTGGACATGCTGGAGTCGGTCAGTCTGTCTAAGCCGGTCACCGTGTGGCTAAAAATTGATTCCGGTA
TGCATCGGCTGGGGTTTCATGCCAGTGAGTTCAAGGACGTTTACCAGAGGCTTCAGCAAAACCCCAATGTGGCAAAACCC
GTGCATCTGATGACCCATTTCAGCTGCGCCGATGAGCCTCAAAAAGACTTTACCGCTACACAGATGGCCCATTTCAACGC
TCTGACCCAGGGGTTACCCGGGGACAGAACCCTGGCAAACTCCGCAGGGGTGCTGTACTGGCCACAAAGCCAGGCCGATT
GGATTCGTCCGGGTATCGCGCTTTACGGAGTTTCTCCAGTGGCGGGTGACCTTGGCAGCAACCACGGTCTTGAACCTGCG
ATGGAGTTGGTCTCGCAATTGATTGCCGTGCGGGAGCACAGCGCCGGGGAGAGTGTGGGTTATGGCGCATACTGGACGGC
CAGTCGTGATACTCGCCTCGGTGTTGTGGCCATAGGTTATGGTGACGGATACCCCCGCAATGCCCCCGAGGGCACGCCAG
TGCTGGTTAATGGCAGACGGGTACCCATTGTTGGTCGGGTCTCCATGGATATGCTGACGGTGGATCTGGGGCCTGACGCC
GCAGATAAAGTGGGTGACAGGGCACTTCTCTGGGGCAAGGAATTGCCCGTGGAAGAAGTGGCTGAACGAATTGGCACCAT
TGCCTATGAGCTGGTGACCAAGTTAACCCCGCGAGTGGCAGTTTGCCTCGATTAA

Upstream 100 bases:

>100_bases
GCGTCTGACCTTTCAGGGGCAATTCTCCCGCTTTGACAATTATGCCGGCCCTCAGTTTGAAGAAGACTGATCATCGCTCG
AATCTCACAAGGCAGATGTA

Downstream 100 bases:

>100_bases
AATAAAACAGGCGCTCATGTGAGCGCCTGTTTTACTTCAGTACAGCACTAATTTTCAAAACAAATCTCAATGTACGCAGT
GCCATAGGGGCTGGTGAATG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADADGFGLARLEEALEVRAGGVSA
RLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSLSKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKP
VHLMTHFSCADEPQKDFTATQMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPA
MELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRRVPIVGRVSMDMLTVDLGPDA
ADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVAVCLD

Sequences:

>Translated_364_residues
MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADADGFGLARLEEALEVRAGGVSA
RLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSLSKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKP
VHLMTHFSCADEPQKDFTATQMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPA
MELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRRVPIVGRVSMDMLTVDLGPDA
ADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVAVCLD
>Mature_364_residues
MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADADGFGLARLEEALEVRAGGVSA
RLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSLSKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKP
VHLMTHFSCADEPQKDFTATQMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPA
MELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRRVPIVGRVSMDMLTVDLGPDA
ADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVAVCLD

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=354, Percent_Identity=58.1920903954802, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1787439, Length=358, Percent_Identity=44.1340782122905, Blast_Score=286, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_SHEAM (A1SA53)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928929.1
- ProteinModelPortal:   A1SA53
- SMR:   A1SA53
- STRING:   A1SA53
- GeneID:   4605304
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_3057
- NMPDR:   fig|326297.7.peg.2875
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   EGTPVWV
- PhylomeDB:   A1SA53
- ProtClustDB:   PRK00053
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 39409; Mature: 39409

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 35-35 ACT_SITE 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
GFGLARLEEALEVRAGGVSARLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSL
CCCHHHHHHHHHHHCCCCCEEHEEHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
SKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKPVHLMTHFSCADEPQKDFTAT
CCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHH
QMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPA
HHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHCCCEEEEECCCCCCCCCCCCCCCHH
MELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRR
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEE
VPIVGRVSMDMLTVDLGPDAADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVA
EEEEEECEEEEEEEECCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
VCLD
EEEC
>Mature Secondary Structure
MKPFPRAEISSRALKANLKRLRQIAPGSKVMAVVKANGYGHGLLNVAEVLTDAHSNADAD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
GFGLARLEEALEVRAGGVSARLLLLEGFFRSEDLPLLVEHDIDTVVHHVSQLDMLESVSL
CCCHHHHHHHHHHHCCCCCEEHEEHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
SKPVTVWLKIDSGMHRLGFHASEFKDVYQRLQQNPNVAKPVHLMTHFSCADEPQKDFTAT
CCCEEEEEEECCCCHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHHHHHH
QMAHFNALTQGLPGDRTLANSAGVLYWPQSQADWIRPGIALYGVSPVAGDLGSNHGLEPA
HHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHCCCEEEEECCCCCCCCCCCCCCCHH
MELVSQLIAVREHSAGESVGYGAYWTASRDTRLGVVAIGYGDGYPRNAPEGTPVLVNGRR
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEE
VPIVGRVSMDMLTVDLGPDAADKVGDRALLWGKELPVEEVAERIGTIAYELVTKLTPRVA
EEEEEECEEEEEEEECCCCHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
VCLD
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA