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The map label for this gene is hflX [H]

Identifier: 119776156

GI number: 119776156

Start: 3598351

End: 3599658

Strand: Reverse

Name: hflX [H]

Synonym: Sama_3024

Alternate gene names: 119776156

Gene position: 3599658-3598351 (Counterclockwise)

Preceding gene: 119776157

Following gene: 119776155

Centisome position: 83.59

GC content: 53.9

Gene sequence:

>1308_bases
TTGTTTGATCGTTATGAGGCGGGAGAAACAGCGGTTCTTGTCCATATCGATTTTACCGACGAAGGCAGTCGGGAAGATCT
CGCCGAATTGCAGTTATTGGTGGAATCGGCGGGTGCACGCTCCGTTGGTGTTATTACAGGAAGCCGTCGCGCGCCTGACC
GCAAGTTTTTTGTGGGTACAGGCAAGGCTGAAGAGCTGGCTGCCATGGTGGCCGCGACCGATGCAAATGTAGTGATTTTT
AACCATGCCCTGAGTCCGGCTCAGGAGCGGAATCTGGAGCACCTGTGTCGTTGTCGGGTGCTCGACAGGACAACCCTGAT
CCTGGATATTTTCGCTCAACGTGCCCGGACCCACGAAGGTAAGTTGCAGGTGGAGCTAGCGCAATTGCGCCACATGTCAA
CGCGCCTCGTGCGGGGCTGGACTCACCTTGAGCGCCAGAAGGGCGGTATTGGTCTGCGTGGTCCAGGTGAAACTCAGTTG
GAAACCGACCGCCGCTTGCTGCGGGGACGGATCAAGAATATTAACCGCCGTCTGGAGAAGGTAGACAAACAGCGGGAGCA
AAGCCGCAGGGCAAGGCAACGCAGTGACATGGCAGCGGTTTCTCTGGTTGGTTATACCAACGCAGGAAAGTCCACCTTGT
TCAATACGTTGACCAGCGCTGAGGTGTACGCCGCCGATCAACTGTTTGCGACTCTGGATCCCACGCTGCGAAAACTCGAG
TTGCCTGACGGTGCCGCGATTCTCGCAGACACAGTAGGATTCATCCGTCACCTTCCACATGACCTGGTTGCCGCCTTCAA
GGCCACGCTGCAAGAGACCCGCGAAGCGGATCTTTTGTTACATGTAATTGATTGTGCAGATGAAAAGATGCGCGACAATA
TAGAGCAAGTGCAGGCGGTACTGAAGGAAATCGACGCCGATGAGATACCTCAACTCATCGTGTGCAACAAGATTGACCTG
GTTGAAGGCATTAAACCCGCCATCGATCGGGATGATACCGGAAAGCCTTTCCGGGTCTGGTTGTCTGCCCAGCAAAACCA
AGGCTTGGATTTGCTCCGGCAGGCGGTTCAGGAGTTGGTTGGCAATGTCATTGCCGAGCTAACCCTGAAAATCCCGGCAA
CCGCCGGGCATTATCTTGGCCAGTTTTATCGACTGGATGCGATACAGCAGAAAGAGTATGACGATCTGGGGAACTGTATC
TTGTCTGTTCGTTTGCCTGATGCCGATTGGCGCAGGCTGGCTAAACAGAGTCAAGGTGAGTTGGAAACCTTTATTGTCGA
TACAGCGACTGATAGGGTAGTTTGTTAA

Upstream 100 bases:

>100_bases
TGGGCAGTCATCAGGGTGGCAGCAGCAACTACAATGCCCAACAAGACGACAGTGCCGGCGAACAGTAATTCCGGACGTCT
ATTTTTGAGAGGTTTGCTTC

Downstream 100 bases:

>100_bases
CTATTAATATCATCCACTTATGGAGTATTAAATGGCTTGGAACGAGCCCGGTAACAAGGGGCAGGACCCTTGGGGAAACA
AAGGCGGCAACGATAAAGGG

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFDRYEAGETAVLVHIDFTDEGSREDLAELQLLVESAGARSVGVITGSRRAPDRKFFVGTGKAEELAAMVAATDANVVIF
NHALSPAQERNLEHLCRCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINRRLEKVDKQREQSRRARQRSDMAAVSLVGYTNAGKSTLFNTLTSAEVYAADQLFATLDPTLRKLE
LPDGAAILADTVGFIRHLPHDLVAAFKATLQETREADLLLHVIDCADEKMRDNIEQVQAVLKEIDADEIPQLIVCNKIDL
VEGIKPAIDRDDTGKPFRVWLSAQQNQGLDLLRQAVQELVGNVIAELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLPDADWRRLAKQSQGELETFIVDTATDRVVC

Sequences:

>Translated_435_residues
MFDRYEAGETAVLVHIDFTDEGSREDLAELQLLVESAGARSVGVITGSRRAPDRKFFVGTGKAEELAAMVAATDANVVIF
NHALSPAQERNLEHLCRCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINRRLEKVDKQREQSRRARQRSDMAAVSLVGYTNAGKSTLFNTLTSAEVYAADQLFATLDPTLRKLE
LPDGAAILADTVGFIRHLPHDLVAAFKATLQETREADLLLHVIDCADEKMRDNIEQVQAVLKEIDADEIPQLIVCNKIDL
VEGIKPAIDRDDTGKPFRVWLSAQQNQGLDLLRQAVQELVGNVIAELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLPDADWRRLAKQSQGELETFIVDTATDRVVC
>Mature_435_residues
MFDRYEAGETAVLVHIDFTDEGSREDLAELQLLVESAGARSVGVITGSRRAPDRKFFVGTGKAEELAAMVAATDANVVIF
NHALSPAQERNLEHLCRCRVLDRTTLILDIFAQRARTHEGKLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRIKNINRRLEKVDKQREQSRRARQRSDMAAVSLVGYTNAGKSTLFNTLTSAEVYAADQLFATLDPTLRKLE
LPDGAAILADTVGFIRHLPHDLVAAFKATLQETREADLLLHVIDCADEKMRDNIEQVQAVLKEIDADEIPQLIVCNKIDL
VEGIKPAIDRDDTGKPFRVWLSAQQNQGLDLLRQAVQELVGNVIAELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCI
LSVRLPDADWRRLAKQSQGELETFIVDTATDRVVC

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=266, Percent_Identity=34.2105263157895, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310133116, Length=264, Percent_Identity=34.469696969697, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310124269, Length=246, Percent_Identity=34.9593495934959, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI310124267, Length=246, Percent_Identity=34.9593495934959, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI310124171, Length=246, Percent_Identity=34.9593495934959, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI310124169, Length=246, Percent_Identity=34.9593495934959, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=65.7276995305164, Blast_Score=560, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17561038, Length=255, Percent_Identity=33.3333333333333, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24650079, Length=361, Percent_Identity=28.808864265928, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129375, Length=133, Percent_Identity=36.0902255639098, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48701; Mature: 48701

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGETAVLVHIDFTDEGSREDLAELQLLVESAGARSVGVITGSRRAPDRKFFVGT
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEC
GKAEELAAMVAATDANVVIFNHALSPAQERNLEHLCRCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINRRLEK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARQRSDMAAVSLVGYTNAGKSTLFNTLTSAEVYAADQLFATLDPTLRKLE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
LPDGAAILADTVGFIRHLPHDLVAAFKATLQETREADLLLHVIDCADEKMRDNIEQVQAV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LKEIDADEIPQLIVCNKIDLVEGIKPAIDRDDTGKPFRVWLSAQQNQGLDLLRQAVQELV
HHHCCHHHCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GNVIAELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLPDADWRRLAKQSQGE
HHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCC
LETFIVDTATDRVVC
EEEEEEECCCCCCCC
>Mature Secondary Structure
MFDRYEAGETAVLVHIDFTDEGSREDLAELQLLVESAGARSVGVITGSRRAPDRKFFVGT
CCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEC
GKAEELAAMVAATDANVVIFNHALSPAQERNLEHLCRCRVLDRTTLILDIFAQRARTHEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRIKNINRRLEK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQREQSRRARQRSDMAAVSLVGYTNAGKSTLFNTLTSAEVYAADQLFATLDPTLRKLE
HHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEE
LPDGAAILADTVGFIRHLPHDLVAAFKATLQETREADLLLHVIDCADEKMRDNIEQVQAV
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LKEIDADEIPQLIVCNKIDLVEGIKPAIDRDDTGKPFRVWLSAQQNQGLDLLRQAVQELV
HHHCCHHHCCCEEEECCHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GNVIAELTLKIPATAGHYLGQFYRLDAIQQKEYDDLGNCILSVRLPDADWRRLAKQSQGE
HHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCC
LETFIVDTATDRVVC
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]