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The map label for this gene is argD [H]

Identifier: 119776143

GI number: 119776143

Start: 3583948

End: 3585162

Strand: Reverse

Name: argD [H]

Synonym: Sama_3011

Alternate gene names: 119776143

Gene position: 3585162-3583948 (Counterclockwise)

Preceding gene: 119776144

Following gene: 119776142

Centisome position: 83.26

GC content: 56.71

Gene sequence:

>1215_bases
ATGACTGACAAGATGAATCTGACACGTGCCCAATTTGATGAAGTAATGGTGCCTAACTATGCACCAGCTGCGGTTATCCC
TGTCCGCGGTGAAGGCAGCCGTGTCTGGGATCAGCAAGGTACCGAGTATGTGGACTTTGCCGGTGGCATCGCGGTGAACT
GTCTTGGTCATTGTCATCCCGCCCTCGTTGGCGCACTGAAAGAGCAGGGCGAGAAACTCTGGCACCTGTCCAACACCATG
ACCAACGAGCCAGCGCTGGCACTGGCTACCAAACTGGTTGAAGCAACCTTTGCCGACCGGGTGTATTTTGCCAACTCAGG
CGCCGAGGCCAACGAAGCGGCACTCAAGCTTGCACGCCGCTATGCAATCGAAAAGTTCGGTGAACACAAGGTTGAAGTGA
TTGCGTTCGACAAGGCTTTCCACGGTCGTACTTTCTTCACCGTGTCTGTGGGTGGCCAGGCCGCTTACTCAGACGGTTTC
GGTCCAAAGCCTGCCGCTATTACCCATTTGCCATTCAATGATATCGCTGCGCTGGAAGCGGCTGTGTCCGACAATACCTG
CGCCATCATGCTCGAGCCACTGCAGGGCGAGGGCGGTATCATCAACGGCGACCCTGAATTCCTGCGTGCCGTTCGTCGAT
TGGCCGACAAGCACAATGCGCTGGTGATCTTCGACGAAGTCCAAACCGGCGTAGGCCGTACCGGCGACCTCTATGCCTAT
ATGGGCACCGAAATCGTGCCGGATATCCTGACCACCGCCAAGGCGTTGGGCGGTGGTTTCCCCATCGCAGCCATGCTGAC
CACTGCCGACATCGCCTCACACCTCAAGGTGGGCACCCATGGTTCCACCTACGGTGGCAACCCGCTGGCCTGTGCCATTG
GTAACGCTGTGATGGACGTTGTTAATACCCCTGAAGTGCTTGACGGCGTGAAGCATCGCGAGCAGCTGTTCCGCGATGGT
CTGGCCCAAATTAATGAAAAGTATCATGTATTCTCCGAAATCCGTGGCAAGGGTCTGCTGCTTGGCGCCGTACTCAACGA
GCAGTTTGCCGGCCGTAGCCGCGATTTCCTTAATGCCTCTGTTGCCGAGGGGCTGTTGACTCTGATGGCCGGTGCCAACG
TAGTCCGCTTTACTCCATCTCTGGTAATTCCTGAGGCAGATATTGTCGAAGGTCTGGCCCGTTTCGAACGTGCCGTTGCC
AAGGTAGCCGGCTGA

Upstream 100 bases:

>100_bases
CCGACACAAGCACATGCTGCAATAAGCCTCAGCAAAAAAGAAAACGCAGCGGCAAACCGGTGGCTTCGCAAGTCACGCAA
CGAACAAAGGATGAACAGGA

Downstream 100 bases:

>100_bases
TATAACGGGGGCGGCACCGGTTGCCGCCCCTGACGATCCAGCGACGTCCTGCTCCCAACCTCCGACATCCGATTTCACCG
AACCAGCCGGTGAGGCTTGG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTDKMNLTRAQFDEVMVPNYAPAAVIPVRGEGSRVWDQQGTEYVDFAGGIAVNCLGHCHPALVGALKEQGEKLWHLSNTM
TNEPALALATKLVEATFADRVYFANSGAEANEAALKLARRYAIEKFGEHKVEVIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPAAITHLPFNDIAALEAAVSDNTCAIMLEPLQGEGGIINGDPEFLRAVRRLADKHNALVIFDEVQTGVGRTGDLYAY
MGTEIVPDILTTAKALGGGFPIAAMLTTADIASHLKVGTHGSTYGGNPLACAIGNAVMDVVNTPEVLDGVKHREQLFRDG
LAQINEKYHVFSEIRGKGLLLGAVLNEQFAGRSRDFLNASVAEGLLTLMAGANVVRFTPSLVIPEADIVEGLARFERAVA
KVAG

Sequences:

>Translated_404_residues
MTDKMNLTRAQFDEVMVPNYAPAAVIPVRGEGSRVWDQQGTEYVDFAGGIAVNCLGHCHPALVGALKEQGEKLWHLSNTM
TNEPALALATKLVEATFADRVYFANSGAEANEAALKLARRYAIEKFGEHKVEVIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPAAITHLPFNDIAALEAAVSDNTCAIMLEPLQGEGGIINGDPEFLRAVRRLADKHNALVIFDEVQTGVGRTGDLYAY
MGTEIVPDILTTAKALGGGFPIAAMLTTADIASHLKVGTHGSTYGGNPLACAIGNAVMDVVNTPEVLDGVKHREQLFRDG
LAQINEKYHVFSEIRGKGLLLGAVLNEQFAGRSRDFLNASVAEGLLTLMAGANVVRFTPSLVIPEADIVEGLARFERAVA
KVAG
>Mature_403_residues
TDKMNLTRAQFDEVMVPNYAPAAVIPVRGEGSRVWDQQGTEYVDFAGGIAVNCLGHCHPALVGALKEQGEKLWHLSNTMT
NEPALALATKLVEATFADRVYFANSGAEANEAALKLARRYAIEKFGEHKVEVIAFDKAFHGRTFFTVSVGGQAAYSDGFG
PKPAAITHLPFNDIAALEAAVSDNTCAIMLEPLQGEGGIINGDPEFLRAVRRLADKHNALVIFDEVQTGVGRTGDLYAYM
GTEIVPDILTTAKALGGGFPIAAMLTTADIASHLKVGTHGSTYGGNPLACAIGNAVMDVVNTPEVLDGVKHREQLFRDGL
AQINEKYHVFSEIRGKGLLLGAVLNEQFAGRSRDFLNASVAEGLLTLMAGANVVRFTPSLVIPEADIVEGLARFERAVAK
VAG

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=35.1282051282051, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=35.7859531772575, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI13994255, Length=415, Percent_Identity=28.1927710843373, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI24119277, Length=393, Percent_Identity=27.4809160305344, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=27.8177458033573, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442709, Length=382, Percent_Identity=28.2722513089005, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI226442705, Length=417, Percent_Identity=26.6187050359712, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI188536080, Length=419, Percent_Identity=23.1503579952267, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679950, Length=419, Percent_Identity=23.1503579952267, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI38679946, Length=419, Percent_Identity=23.1503579952267, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789759, Length=402, Percent_Identity=63.18407960199, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1788044, Length=393, Percent_Identity=58.2697201017812, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1789016, Length=399, Percent_Identity=35.5889724310777, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI145693181, Length=394, Percent_Identity=35.2791878172589, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=33.2493702770781, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786991, Length=328, Percent_Identity=33.8414634146341, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=29.9684542586751, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=34.8404255319149, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=28.8329519450801, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=254, Percent_Identity=34.6456692913386, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=27.0833333333333, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=419, Percent_Identity=25.5369928400955, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=33.125, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=38.6363636363636, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.8308457711443, Blast_Score=206, Evalue=6e-54,
Organism=Saccharomyces cerevisiae, GI6324386, Length=359, Percent_Identity=28.133704735376, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=428, Percent_Identity=25.2336448598131, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357415, Length=386, Percent_Identity=35.4922279792746, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI28574759, Length=412, Percent_Identity=30.3398058252427, Blast_Score=178, Evalue=6e-45,
Organism=Drosophila melanogaster, GI161085790, Length=423, Percent_Identity=29.7872340425532, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356575, Length=364, Percent_Identity=30.2197802197802, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43097; Mature: 42965

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKMNLTRAQFDEVMVPNYAPAAVIPVRGEGSRVWDQQGTEYVDFAGGIAVNCLGHCHP
CCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHCCCCEEEECCCCHHHHHHHHHHH
ALVGALKEQGEKLWHLSNTMTNEPALALATKLVEATFADRVYFANSGAEANEAALKLARR
HHHHHHHHHCHHEEHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
YAIEKFGEHKVEVIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPAAITHLPFNDIAALEA
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCEEEECCCHHHHHHHH
AVSDNTCAIMLEPLQGEGGIINGDPEFLRAVRRLADKHNALVIFDEVQTGVGRTGDLYAY
HHCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEE
MGTEIVPDILTTAKALGGGFPIAAMLTTADIASHLKVGTHGSTYGGNPLACAIGNAVMDV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLDGVKHREQLFRDGLAQINEKYHVFSEIRGKGLLLGAVLNEQFAGRSRDFLNAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHH
VAEGLLTLMAGANVVRFTPSLVIPEADIVEGLARFERAVAKVAG
HHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDKMNLTRAQFDEVMVPNYAPAAVIPVRGEGSRVWDQQGTEYVDFAGGIAVNCLGHCHP
CCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHCCCCEEEECCCCHHHHHHHHHHH
ALVGALKEQGEKLWHLSNTMTNEPALALATKLVEATFADRVYFANSGAEANEAALKLARR
HHHHHHHHHCHHEEHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHH
YAIEKFGEHKVEVIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPAAITHLPFNDIAALEA
HHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCEEEECCCHHHHHHHH
AVSDNTCAIMLEPLQGEGGIINGDPEFLRAVRRLADKHNALVIFDEVQTGVGRTGDLYAY
HHCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEE
MGTEIVPDILTTAKALGGGFPIAAMLTTADIASHLKVGTHGSTYGGNPLACAIGNAVMDV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLDGVKHREQLFRDGLAQINEKYHVFSEIRGKGLLLGAVLNEQFAGRSRDFLNAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCHHHHHHH
VAEGLLTLMAGANVVRFTPSLVIPEADIVEGLARFERAVAKVAG
HHHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]