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The map label for this gene is phoP [H]

Identifier: 119776138

GI number: 119776138

Start: 3578268

End: 3578942

Strand: Direct

Name: phoP [H]

Synonym: Sama_3006

Alternate gene names: 119776138

Gene position: 3578268-3578942 (Clockwise)

Preceding gene: 119776137

Following gene: 119776139

Centisome position: 83.1

GC content: 54.37

Gene sequence:

>675_bases
ATGAAACTGCTACTCGTTGAAGACAATGCCATGCTGGTCAAGGAGCTGCAAAAACAGCTCAAACAGGCCGGCTTTGTCAC
CGATGTAACCGATAAGGTCGTTGACGCCGATTATCTCATCAAAGAAACCCAATACGACTGCGTGATTCTGGACATCGGCC
TTCCCGATGGCAACGGTCTGACACTACTGGAAAAATGGCGTACCGAGGGTATTCATACCCCCGTGATCATGCTCACCGCC
CGCAGCCAATGGCATGAGAAGGTGGAAGGCTTTAACGCCGGTGCCGATGACTACCTTGGTAAACCGTTCCACGCCCAGGA
GTTGCTCGCCCGAATTCATGCGCTGATAAACCGCGCCCATGGCCGCCCTGCCAGCCCGGGAAAGCAGCTCAGCTACTCAG
GCGTCGTACTGGATGAATCGCAGCAAACGGTGCAGGTGGGTGAGCAGGTCCATGAGCTGACTGCCATGGAATTCAGACTG
CTGAAGATTTTCCTGCTATCGCCGAAAAAGCTGCTGTCCAAGGCGCAGCTTACCGACAAGCTCTATCAGTTTGACGATGA
GAAAGAGAGCAATGTGGTGGAGGTTTACGTGACCCACCTGCGTAAAAAACTGGGCAAGACCGCCATCGAAACCCGCCGCG
GTCAGGGATATATCTTCCACGGCCTGGACGCATGA

Upstream 100 bases:

>100_bases
CAGTTTGGCCTCCAACGTGGTCAGATAATCCATCTGAGCGTGGATGCCGCCAGCGGTGAGCTCAATCCTGATTCCACTTT
GCCGGACGAATGCAAAAACC

Downstream 100 bases:

>100_bases
TCTCCATTCGGGCCAAGCTGAGCCTGTGGTTAACCGGCCTGGTGATAGTCAGCACTATCATCGGGCTGTTTTTGTTTGAG
TCCATGCTCAGACAAGCCTT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKLLLVEDNAMLVKELQKQLKQAGFVTDVTDKVVDADYLIKETQYDCVILDIGLPDGNGLTLLEKWRTEGIHTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIHALINRAHGRPASPGKQLSYSGVVLDESQQTVQVGEQVHELTAMEFRL
LKIFLLSPKKLLSKAQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGLDA

Sequences:

>Translated_224_residues
MKLLLVEDNAMLVKELQKQLKQAGFVTDVTDKVVDADYLIKETQYDCVILDIGLPDGNGLTLLEKWRTEGIHTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIHALINRAHGRPASPGKQLSYSGVVLDESQQTVQVGEQVHELTAMEFRL
LKIFLLSPKKLLSKAQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGLDA
>Mature_224_residues
MKLLLVEDNAMLVKELQKQLKQAGFVTDVTDKVVDADYLIKETQYDCVILDIGLPDGNGLTLLEKWRTEGIHTPVIMLTA
RSQWHEKVEGFNAGADDYLGKPFHAQELLARIHALINRAHGRPASPGKQLSYSGVVLDESQQTVQVGEQVHELTAMEFRL
LKIFLLSPKKLLSKAQLTDKLYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGLDA

Specific function: Member of the two-component regulatory system phoQ/phoP which regulates the expression of genes involved in virulence and resistance to host defense antimicrobial peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=37.6681614349776, Blast_Score=163, Evalue=8e-42,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=36.986301369863, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=35.1598173515982, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=34.2222222222222, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=32.5892857142857, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=33.6322869955157, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=32.7510917030568, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=31.8385650224215, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.004329004329, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787229, Length=222, Percent_Identity=30.6306306306306, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788394, Length=209, Percent_Identity=29.1866028708134, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=32.3404255319149, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=30.1724137931034, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=31.7757009345794, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25282; Mature: 25282

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLVEDNAMLVKELQKQLKQAGFVTDVTDKVVDADYLIKETQYDCVILDIGLPDGNGL
CEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TLLEKWRTEGIHTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHAQELLARIHALINRAH
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GRPASPGKQLSYSGVVLDESQQTVQVGEQVHELTAMEFRLLKIFLLSPKKLLSKAQLTDK
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGLDA
HHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MKLLLVEDNAMLVKELQKQLKQAGFVTDVTDKVVDADYLIKETQYDCVILDIGLPDGNGL
CEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
TLLEKWRTEGIHTPVIMLTARSQWHEKVEGFNAGADDYLGKPFHAQELLARIHALINRAH
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GRPASPGKQLSYSGVVLDESQQTVQVGEQVHELTAMEFRLLKIFLLSPKKLLSKAQLTDK
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYQFDDEKESNVVEVYVTHLRKKLGKTAIETRRGQGYIFHGLDA
HHHCCCCCCCCHHHHHHHHHHHHHCHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA