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The map label for this gene is yhcK [H]

Identifier: 119776121

GI number: 119776121

Start: 3559985

End: 3561718

Strand: Direct

Name: yhcK [H]

Synonym: Sama_2989

Alternate gene names: 119776121

Gene position: 3559985-3561718 (Clockwise)

Preceding gene: 119776120

Following gene: 119776122

Centisome position: 82.67

GC content: 53.52

Gene sequence:

>1734_bases
ATGCTTACGCGCGCTGTGTCATTGCTGACAAGGATAATGTTACTGCTGATGTGCGCCTCTGCCAGCTCTCTGTGGGCATC
AGAGCCCGGGCAAATTGCCGACAGAACCATTGAAGTGGGCGAAGGAGACGTGGCGTTGACAGAATTCGCCACCGGCTATT
TTGTCGACCCAAGCCAGCAAATGTCACTGGCGGAGGTACAGCTGCAGGATTTTATCCCCGGCGGCAGCAGCATCACCCTG
GGCACCAATGCCAAGACGACCTGGTCGCGGCTTGAGGTCCACAATACTGCATCTCACAGTCGGCGCTTATTCATCCATCA
CCCCCACGCCTACCATCTGCAAAGCATCAATTTCTATGAAACCCGCCAGAATGAGCTGCTGAGCCAGGCCGATATTCACC
TAGACAGGGACGAGTCGCACCCCATGATGTTTGGCGGCAGCGCGGTATATGCCTTTGACATTGCCGCCGGCGAGCGCAAA
ACCATCTACATCAAAAATGTGACCTTTTCTCACCAGTGGTACAGCCTTGCGTTATACGACGAAGAGCATTCCAAACGAGC
CTTGGTAGGCAGCGGTAACTACATGGCACTGCTGGTTGGCATGATGTTGGCGCTGATGATTTACAACTTCTTTTTATATC
TGTCGGCCCGCAAAGTCGAAAATGTGGTGTATGCCCTTTACCTCATTTCGGGCACCATCTGGGTGGGTTTGTCTTATGGG
GTGGCGGCCAACTTTCTGGGCGTTTACAGCGCGGCCTTATTGCAGCTCAACTCAAACCTGCTCAGCATGCCCAGCTTTTT
GGTGCTGTTTATGATGCTGATTTTCGAGACCCGCCGCCGCTACCCCAGGGAGCATCTGGCGCTGAGCCTGATGCTGACAC
TCCTGGTTGCCGACTTTATTTACAGTTTGTTTGATGTGGTCGGAGCCCTCAAGCCCGCCAGCAGCCTGGCGGCCATGATG
ATGGTGGTCACCTTTGGTGTGTCATTGTCTTTGTGGCGTAAAGGTGAGCCCCTGGCCAAGTATTTCCTGCTGGGACATTC
GATGTTTATCATCTTCAATATGTCGGCCGTGTTTTATTACAAGGGCTTAAGTCAGGCCAATCAAATCAACAGTCATGGTG
TCGGCATCGGCATTCTGCTGGAAGCATTGATGATGGCCTTCATCCTGTCGTACCGGATTAAAACCCTTGAGCAACTCAAG
GCCAAACAGGGGGAGCTGAAGCGCCAGGCAAACACAGATCCCATGACGCACCTCTTTAACCGACGCTACTTTGATGTGAC
CAGCCCGCTCTTGCTGACCGAGGCCAAAGCGACAGGCGCCCACTGGACCCTGTTGATCATCGACATAGATAATTTCAAGT
CCATTAACGACACCTATGGTCACCATGTGGGGGATCTGGTGATAATCGAATTCGCCGCCGTACTCAAACAAAACCAGCGA
CCTCAGGATATCGCCTGTCGCTTCGGTGGTGATGAGTTTGTGTTGCTGCTCAACTGCAATTTGGACAACGCCACCCGCAT
TGCCGAGCGCATCCGTGCGAACACCGAAAGGCTGCCGATAACCACTCAGGAAGGTGAAAAGCTGCACTTCACCGTGAGTA
TTGGGGTGCATCCTGTATCATCCAGCGCTGACAACATGCAAGAAGCGCTGCAGGGCGCCGATGCCGCTTTGTATGAGTCC
AAGGGGCTTGGACGCAACAAGGTGGTCAGTCGCTTGAACGGCTCAGCGGCATAG

Upstream 100 bases:

>100_bases
CAGCCCGCTGTGCGTTGCCTCCCTGTTAACGGCTCGATAAAGCCATTGAGGTCCTTTATGATTGGCTATCTGTAGCCATT
TATTTAAATTGGATTTTTTG

Downstream 100 bases:

>100_bases
CCTGCTCCTGAACTTGTCACTGATGTATTAACAAGTCGGTGGCAACGTTTGCTCACAGAAGTTATCCAGTAAAAGACACC
TTGCCGCCCTATTGAAGTTG

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MLTRAVSLLTRIMLLLMCASASSLWASEPGQIADRTIEVGEGDVALTEFATGYFVDPSQQMSLAEVQLQDFIPGGSSITL
GTNAKTTWSRLEVHNTASHSRRLFIHHPHAYHLQSINFYETRQNELLSQADIHLDRDESHPMMFGGSAVYAFDIAAGERK
TIYIKNVTFSHQWYSLALYDEEHSKRALVGSGNYMALLVGMMLALMIYNFFLYLSARKVENVVYALYLISGTIWVGLSYG
VAANFLGVYSAALLQLNSNLLSMPSFLVLFMMLIFETRRRYPREHLALSLMLTLLVADFIYSLFDVVGALKPASSLAAMM
MVVTFGVSLSLWRKGEPLAKYFLLGHSMFIIFNMSAVFYYKGLSQANQINSHGVGIGILLEALMMAFILSYRIKTLEQLK
AKQGELKRQANTDPMTHLFNRRYFDVTSPLLLTEAKATGAHWTLLIIDIDNFKSINDTYGHHVGDLVIIEFAAVLKQNQR
PQDIACRFGGDEFVLLLNCNLDNATRIAERIRANTERLPITTQEGEKLHFTVSIGVHPVSSSADNMQEALQGADAALYES
KGLGRNKVVSRLNGSAA

Sequences:

>Translated_577_residues
MLTRAVSLLTRIMLLLMCASASSLWASEPGQIADRTIEVGEGDVALTEFATGYFVDPSQQMSLAEVQLQDFIPGGSSITL
GTNAKTTWSRLEVHNTASHSRRLFIHHPHAYHLQSINFYETRQNELLSQADIHLDRDESHPMMFGGSAVYAFDIAAGERK
TIYIKNVTFSHQWYSLALYDEEHSKRALVGSGNYMALLVGMMLALMIYNFFLYLSARKVENVVYALYLISGTIWVGLSYG
VAANFLGVYSAALLQLNSNLLSMPSFLVLFMMLIFETRRRYPREHLALSLMLTLLVADFIYSLFDVVGALKPASSLAAMM
MVVTFGVSLSLWRKGEPLAKYFLLGHSMFIIFNMSAVFYYKGLSQANQINSHGVGIGILLEALMMAFILSYRIKTLEQLK
AKQGELKRQANTDPMTHLFNRRYFDVTSPLLLTEAKATGAHWTLLIIDIDNFKSINDTYGHHVGDLVIIEFAAVLKQNQR
PQDIACRFGGDEFVLLLNCNLDNATRIAERIRANTERLPITTQEGEKLHFTVSIGVHPVSSSADNMQEALQGADAALYES
KGLGRNKVVSRLNGSAA
>Mature_577_residues
MLTRAVSLLTRIMLLLMCASASSLWASEPGQIADRTIEVGEGDVALTEFATGYFVDPSQQMSLAEVQLQDFIPGGSSITL
GTNAKTTWSRLEVHNTASHSRRLFIHHPHAYHLQSINFYETRQNELLSQADIHLDRDESHPMMFGGSAVYAFDIAAGERK
TIYIKNVTFSHQWYSLALYDEEHSKRALVGSGNYMALLVGMMLALMIYNFFLYLSARKVENVVYALYLISGTIWVGLSYG
VAANFLGVYSAALLQLNSNLLSMPSFLVLFMMLIFETRRRYPREHLALSLMLTLLVADFIYSLFDVVGALKPASSLAAMM
MVVTFGVSLSLWRKGEPLAKYFLLGHSMFIIFNMSAVFYYKGLSQANQINSHGVGIGILLEALMMAFILSYRIKTLEQLK
AKQGELKRQANTDPMTHLFNRRYFDVTSPLLLTEAKATGAHWTLLIIDIDNFKSINDTYGHHVGDLVIIEFAAVLKQNQR
PQDIACRFGGDEFVLLLNCNLDNATRIAERIRANTERLPITTQEGEKLHFTVSIGVHPVSSSADNMQEALQGADAALYES
KGLGRNKVVSRLNGSAA

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=43.1137724550898, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI145693134, Length=193, Percent_Identity=35.2331606217617, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786584, Length=195, Percent_Identity=34.8717948717949, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081881, Length=207, Percent_Identity=35.7487922705314, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=35.3932584269663, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788381, Length=165, Percent_Identity=35.1515151515151, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788085, Length=185, Percent_Identity=33.5135135135135, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787802, Length=191, Percent_Identity=35.0785340314136, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788956, Length=178, Percent_Identity=35.9550561797753, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=157, Percent_Identity=31.2101910828025, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=32.3699421965318, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64352; Mature: 64352

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRAVSLLTRIMLLLMCASASSLWASEPGQIADRTIEVGEGDVALTEFATGYFVDPSQQ
CCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHCCEEECCCCCEEEEECCCCEEECCHHC
MSLAEVQLQDFIPGGSSITLGTNAKTTWSRLEVHNTASHSRRLFIHHPHAYHLQSINFYE
CHHHHHHHHHCCCCCCEEEECCCCCCHHHHEEECCCCCCCCEEEEECCCCEEECCCCHHH
TRQNELLSQADIHLDRDESHPMMFGGSAVYAFDIAAGERKTIYIKNVTFSHQWYSLALYD
HHHHHHHHHHCCEECCCCCCCEEECCCEEEEEEECCCCCEEEEEEEEEECCCEEEEEEEC
EEHSKRALVGSGNYMALLVGMMLALMIYNFFLYLSARKVENVVYALYLISGTIWVGLSYG
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
VAANFLGVYSAALLQLNSNLLSMPSFLVLFMMLIFETRRRYPREHLALSLMLTLLVADFI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YSLFDVVGALKPASSLAAMMMVVTFGVSLSLWRKGEPLAKYFLLGHSMFIIFNMSAVFYY
HHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCEEEEEEHHHHHHH
KGLSQANQINSHGVGIGILLEALMMAFILSYRIKTLEQLKAKQGELKRQANTDPMTHLFN
HCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
RRYFDVTSPLLLTEAKATGAHWTLLIIDIDNFKSINDTYGHHVGDLVIIEFAAVLKQNQR
CCEECCCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHCCCC
PQDIACRFGGDEFVLLLNCNLDNATRIAERIRANTERLPITTQEGEKLHFTVSIGVHPVS
CCHHEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEECC
SSADNMQEALQGADAALYESKGLGRNKVVSRLNGSAA
CCHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MLTRAVSLLTRIMLLLMCASASSLWASEPGQIADRTIEVGEGDVALTEFATGYFVDPSQQ
CCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHCCEEECCCCCEEEEECCCCEEECCHHC
MSLAEVQLQDFIPGGSSITLGTNAKTTWSRLEVHNTASHSRRLFIHHPHAYHLQSINFYE
CHHHHHHHHHCCCCCCEEEECCCCCCHHHHEEECCCCCCCCEEEEECCCCEEECCCCHHH
TRQNELLSQADIHLDRDESHPMMFGGSAVYAFDIAAGERKTIYIKNVTFSHQWYSLALYD
HHHHHHHHHHCCEECCCCCCCEEECCCEEEEEEECCCCCEEEEEEEEEECCCEEEEEEEC
EEHSKRALVGSGNYMALLVGMMLALMIYNFFLYLSARKVENVVYALYLISGTIWVGLSYG
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHH
VAANFLGVYSAALLQLNSNLLSMPSFLVLFMMLIFETRRRYPREHLALSLMLTLLVADFI
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
YSLFDVVGALKPASSLAAMMMVVTFGVSLSLWRKGEPLAKYFLLGHSMFIIFNMSAVFYY
HHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCEEEEEEHHHHHHH
KGLSQANQINSHGVGIGILLEALMMAFILSYRIKTLEQLKAKQGELKRQANTDPMTHLFN
HCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHC
RRYFDVTSPLLLTEAKATGAHWTLLIIDIDNFKSINDTYGHHVGDLVIIEFAAVLKQNQR
CCEECCCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHCCCHHHHHHHHHHHHHHHCCCC
PQDIACRFGGDEFVLLLNCNLDNATRIAERIRANTERLPITTQEGEKLHFTVSIGVHPVS
CCHHEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCEECCCCCEEEEEEEEEEEECC
SSADNMQEALQGADAALYESKGLGRNKVVSRLNGSAA
CCHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]