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The map label for this gene is nqrA [H]

Identifier: 119776113

GI number: 119776113

Start: 3550584

End: 3551951

Strand: Reverse

Name: nqrA [H]

Synonym: Sama_2981

Alternate gene names: 119776113

Gene position: 3551951-3550584 (Counterclockwise)

Preceding gene: 119776119

Following gene: 119776112

Centisome position: 82.49

GC content: 58.04

Gene sequence:

>1368_bases
ATGGCAGATTATTCCGAAGCGATAATCACAGTGAAAAAGGGCCTGGATGTGCCCATTGCAGGTGCGCCAAGGCAAGAGAT
AGACATAGCCGCCAAACCTTCCCAATTGGCCTTGCTTGGCAAGGAGTATGTGGGGCTTAAGCCTTCCATGCTGGTGGAAG
AGGGCGAGCGGGTCATCAAGGGTCAGGCGCTGTTTGAAGACAAGAGCAACCCGGGTGTGCGCTTTACCGCGCCCTGCGCC
GGGATTGTGTCTGCTATCCACAGAGGCGACAAACGCTTGCTGCTGTCGGTGGTCATCGATTGTGATGGCTCTGATGAGAG
CATCGACTTTGGCGTTGAGGCAAACCTTGCCGCCCTGTCCCGAGAGCAGGTGCAGGACAAACTGCTGCAAAGTGGTTTGT
GGACCGCACTTCGCACCCGTCCATTCTCCCGCGCGCCCAAACCGGGCTCAGCGCCTGCCGGTCTGTTTGTTACGGCGGTT
GACACCAATCCGCTGGCCGCTGATCCGCGCATTATTATCAATACCGATGTGGATGCATTCGCCGCCGGTATGCAGGTACT
TACTCACCTCACCGACGGGCCTGTGTTTTTGTGTCAGGACGGTAATCATGAGCTGCTGCCGGGTGCCGAACTGCCGCGGG
TGCAAACCCACAGATTCCAGGGTGTGCACCCTGCTGGGTTAGTGGGCACTCACATTCATATGCTGATGCCCGTCAGCATG
GAGCGTCAGGTGTGGCACATAGGCTATCAGGACGTGATGGCCGTCGGTCGCCTCTTTACCACGGGACAGCTGGATAACCG
CCGCATCGTGTCCCTTGCCGGCCCCAATGTGCTTAAGCCAAGGCTGATTGCCACAGTGCTGGGTGCCAAGGTCAGCGATC
TGGTGAAGGGTGAGCTCAAAGACGAGGTACATTCCCGCGTGGTATCCGGCTCAGTGCTTTCTGGCCATACCGCCCGCGGC
GCCTTTGATTTTCTCGGTCGCTTCCATCCACAGATTTCGGTTGTTACCGAAGATGACAGCGAGCAATTCCTGCCCTGGGT
TCGCCTTGGCCGGGACAAGTTCTCCATCACCCGTACTGTGCTGTCGCGTTTTTTGCCCAAAAAGCTCTACGACATGACCA
CCCATACCGGCGGTGCCAAGCGTGCCATGATGGCCTTCGGTCAGCTGGACCGGGTGATGCCGCTGGATATTCTGCCCACT
CTGCTGGTGCGGGATCTGGTGGTACGTGACACCGACGAGGCGCAGCTTTTGGGCGCGCTGGAGCTGGATGAAGAAGATTT
GGCGCTGTGCACCTTCGTGTGCCCCAGTAAGTACGATTTTGGCCAGGAGCTTCGCGCCTGCCTGACGATTATCGAGAGGG
AAGGCTAA

Upstream 100 bases:

>100_bases
AATTTCATATTTAAGCCATTTGTGATGTGGCTGACGGAATTTTGTGTCTCAACTGGGTACGATCGCTCGCAGTGTATTTT
CCAAGAGAGCGACCGCAATC

Downstream 100 bases:

>100_bases
TGAGCAAGCCCACAAAGAAACCCAGTGCCCAGGACGCTTACTACGCTCCCGGACACACGATGAAAGACTTTTTCCGCTCG
CTGTTTATCGGCCATGGCGC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MADYSEAIITVKKGLDVPIAGAPRQEIDIAAKPSQLALLGKEYVGLKPSMLVEEGERVIKGQALFEDKSNPGVRFTAPCA
GIVSAIHRGDKRLLLSVVIDCDGSDESIDFGVEANLAALSREQVQDKLLQSGLWTALRTRPFSRAPKPGSAPAGLFVTAV
DTNPLAADPRIIINTDVDAFAAGMQVLTHLTDGPVFLCQDGNHELLPGAELPRVQTHRFQGVHPAGLVGTHIHMLMPVSM
ERQVWHIGYQDVMAVGRLFTTGQLDNRRIVSLAGPNVLKPRLIATVLGAKVSDLVKGELKDEVHSRVVSGSVLSGHTARG
AFDFLGRFHPQISVVTEDDSEQFLPWVRLGRDKFSITRTVLSRFLPKKLYDMTTHTGGAKRAMMAFGQLDRVMPLDILPT
LLVRDLVVRDTDEAQLLGALELDEEDLALCTFVCPSKYDFGQELRACLTIIEREG

Sequences:

>Translated_455_residues
MADYSEAIITVKKGLDVPIAGAPRQEIDIAAKPSQLALLGKEYVGLKPSMLVEEGERVIKGQALFEDKSNPGVRFTAPCA
GIVSAIHRGDKRLLLSVVIDCDGSDESIDFGVEANLAALSREQVQDKLLQSGLWTALRTRPFSRAPKPGSAPAGLFVTAV
DTNPLAADPRIIINTDVDAFAAGMQVLTHLTDGPVFLCQDGNHELLPGAELPRVQTHRFQGVHPAGLVGTHIHMLMPVSM
ERQVWHIGYQDVMAVGRLFTTGQLDNRRIVSLAGPNVLKPRLIATVLGAKVSDLVKGELKDEVHSRVVSGSVLSGHTARG
AFDFLGRFHPQISVVTEDDSEQFLPWVRLGRDKFSITRTVLSRFLPKKLYDMTTHTGGAKRAMMAFGQLDRVMPLDILPT
LLVRDLVVRDTDEAQLLGALELDEEDLALCTFVCPSKYDFGQELRACLTIIEREG
>Mature_454_residues
ADYSEAIITVKKGLDVPIAGAPRQEIDIAAKPSQLALLGKEYVGLKPSMLVEEGERVIKGQALFEDKSNPGVRFTAPCAG
IVSAIHRGDKRLLLSVVIDCDGSDESIDFGVEANLAALSREQVQDKLLQSGLWTALRTRPFSRAPKPGSAPAGLFVTAVD
TNPLAADPRIIINTDVDAFAAGMQVLTHLTDGPVFLCQDGNHELLPGAELPRVQTHRFQGVHPAGLVGTHIHMLMPVSME
RQVWHIGYQDVMAVGRLFTTGQLDNRRIVSLAGPNVLKPRLIATVLGAKVSDLVKGELKDEVHSRVVSGSVLSGHTARGA
FDFLGRFHPQISVVTEDDSEQFLPWVRLGRDKFSITRTVLSRFLPKKLYDMTTHTGGAKRAMMAFGQLDRVMPLDILPTL
LVRDLVVRDTDEAQLLGALELDEEDLALCTFVCPSKYDFGQELRACLTIIEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49636; Mature: 49505

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYSEAIITVKKGLDVPIAGAPRQEIDIAAKPSQLALLGKEYVGLKPSMLVEEGERVIK
CCCCHHHHEEEECCCCCCCCCCCHHCCEEECCCCHHEEECHHHCCCCHHHHHHHCHHHHC
GQALFEDKSNPGVRFTAPCAGIVSAIHRGDKRLLLSVVIDCDGSDESIDFGVEANLAALS
CCEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEECCCCCHHHHH
REQVQDKLLQSGLWTALRTRPFSRAPKPGSAPAGLFVTAVDTNPLAADPRIIINTDVDAF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCHHHH
AAGMQVLTHLTDGPVFLCQDGNHELLPGAELPRVQTHRFQGVHPAGLVGTHIHMLMPVSM
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHEEECCCC
ERQVWHIGYQDVMAVGRLFTTGQLDNRRIVSLAGPNVLKPRLIATVLGAKVSDLVKGELK
CCCEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DEVHSRVVSGSVLSGHTARGAFDFLGRFHPQISVVTEDDSEQFLPWVRLGRDKFSITRTV
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHCHHHHHCCCHHHHHHHH
LSRFLPKKLYDMTTHTGGAKRAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQLLGAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEE
ELDEEDLALCTFVCPSKYDFGQELRACLTIIEREG
ECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADYSEAIITVKKGLDVPIAGAPRQEIDIAAKPSQLALLGKEYVGLKPSMLVEEGERVIK
CCCHHHHEEEECCCCCCCCCCCHHCCEEECCCCHHEEECHHHCCCCHHHHHHHCHHHHC
GQALFEDKSNPGVRFTAPCAGIVSAIHRGDKRLLLSVVIDCDGSDESIDFGVEANLAALS
CCEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEECCCCCHHHHH
REQVQDKLLQSGLWTALRTRPFSRAPKPGSAPAGLFVTAVDTNPLAADPRIIINTDVDAF
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCHHHH
AAGMQVLTHLTDGPVFLCQDGNHELLPGAELPRVQTHRFQGVHPAGLVGTHIHMLMPVSM
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHEEECCCC
ERQVWHIGYQDVMAVGRLFTTGQLDNRRIVSLAGPNVLKPRLIATVLGAKVSDLVKGELK
CCCEEECCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
DEVHSRVVSGSVLSGHTARGAFDFLGRFHPQISVVTEDDSEQFLPWVRLGRDKFSITRTV
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHCHHHHHCCCHHHHHHHH
LSRFLPKKLYDMTTHTGGAKRAMMAFGQLDRVMPLDILPTLLVRDLVVRDTDEAQLLGAL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEE
ELDEEDLALCTFVCPSKYDFGQELRACLTIIEREG
ECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA