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The map label for this gene is rstB [H]

Identifier: 119775832

GI number: 119775832

Start: 3230957

End: 3232195

Strand: Direct

Name: rstB [H]

Synonym: Sama_2700

Alternate gene names: 119775832

Gene position: 3230957-3232195 (Clockwise)

Preceding gene: 119775831

Following gene: 119775833

Centisome position: 75.03

GC content: 50.36

Gene sequence:

>1239_bases
TTGCTGACCCGATTTCTGGGCTATTACGCCCTGGTTGTTTTGGTAACCTTTGCCGTTATTTTTATTGGTGACTACAGTTT
TCAGCGTTACCAGCAACGCGCAGAAGTACAGGTGGATTTGCATTATCTGTTTGAGCTGGCTGACGACTATTGCCGGTCTC
AGGTCTGCCAACCGCACACATCTCTGCCTTTTTCGCAGCTCTCCCTGATAGACACCCGCAGTATTCAAATGCCGGCGGAA
AGCTGGCAACGATTGGCGACAGGCGAAATACTGGCACTGTCGATGGGGGAAGATGAGATCTATTATCGCGCGATGACAAA
GGACATGTTATTGCAATTTGGCCCCATCCCGGCCAAACCTCACCCGGGTTGGTATGTCACCGCCTTTTACTTATTATTGG
CAACGCTAATCCTGATGGGGCTGTACCCGCTGTTTCGGGACATGTATCGCCTCAGGGAAGTCAGCCTTCGCTTCAGTAAA
AACCGTCAATTCGAGTCGCTGCAACTGCCAACATCACGCTATTTTCAGCCGGTTAACGATGCCATCTTTTGGATGGTGAA
TAAAATTGCGCGTTTGTTGGCCCTGCAAAAAGAACTCTCCCATACCCTGTCCCACGAGATGCGCACCAGCCTGAGCAGAC
TCAACTTCACCCTTGCCATATTGGACCGGGACAATCTGGAAGAGTGCCGTGACACCCTGCAAGAAGACATTGATGAGCTC
AATACGCTGGTGAAAGAATACCTGGATTTTTCCCGACTGGAGCATCTAACGCCAAAACTGGATCTGGGGCTGCTCAATTT
AACCGTCCCCATACGCCACTACATTGGGTTACTGGGTCAGTATTCTGACAAGCATATTGAGTTCCATGAACTCTGTACCA
CGCCAATCGCTGCCGATGAGCGCCTGATGGCAAGGGCTATCAAAAACCTGATAGACAATGCCATCAAGTACTCTGCTTCC
AAAGTCCTGATCCGCTGTTCCAGTACTGAGCAAGGGGTGTGCGTGTTGATAGAAGACGACGGAGAAGGACTTCTGACAGA
CAAAATTGACGAGCTTTTCATGCCTTACGTGCGCAGTGGTGCTGGAAGAAACCTACCTGGATATGGTCTCGGACTTGCCA
TCACCCGAAAAATTGTCGACTGGCACGGCGGTACAATTGAAGCCGGCAGGAGTGATTCTCTGGGCGGGGCCTGTTTCAAA
CTGGTACTGCCAGTGTCTGTACCCACACAGGTAAATTAA

Upstream 100 bases:

>100_bases
TCAGTCGTTTACGTAAGAAACTGGAAACCAACAAAAAGGTTCGTTGCCGTATCTATACGTCCTGGGGGCAGGGTTACATG
CTGTCGGAGAAAGACCTGAA

Downstream 100 bases:

>100_bases
GTCATACAACGCACCTCAGATTAGCAGGGGAAGGCCGAAGCACTGCCGGGATTAGTGTTTGAATTTCTCACCAATCTCTG
TAGCTTAGAACGCACTGTTC

Product: sensory histidine kinase in two-component regulatory system with RstA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MLTRFLGYYALVVLVTFAVIFIGDYSFQRYQQRAEVQVDLHYLFELADDYCRSQVCQPHTSLPFSQLSLIDTRSIQMPAE
SWQRLATGEILALSMGEDEIYYRAMTKDMLLQFGPIPAKPHPGWYVTAFYLLLATLILMGLYPLFRDMYRLREVSLRFSK
NRQFESLQLPTSRYFQPVNDAIFWMVNKIARLLALQKELSHTLSHEMRTSLSRLNFTLAILDRDNLEECRDTLQEDIDEL
NTLVKEYLDFSRLEHLTPKLDLGLLNLTVPIRHYIGLLGQYSDKHIEFHELCTTPIAADERLMARAIKNLIDNAIKYSAS
KVLIRCSSTEQGVCVLIEDDGEGLLTDKIDELFMPYVRSGAGRNLPGYGLGLAITRKIVDWHGGTIEAGRSDSLGGACFK
LVLPVSVPTQVN

Sequences:

>Translated_412_residues
MLTRFLGYYALVVLVTFAVIFIGDYSFQRYQQRAEVQVDLHYLFELADDYCRSQVCQPHTSLPFSQLSLIDTRSIQMPAE
SWQRLATGEILALSMGEDEIYYRAMTKDMLLQFGPIPAKPHPGWYVTAFYLLLATLILMGLYPLFRDMYRLREVSLRFSK
NRQFESLQLPTSRYFQPVNDAIFWMVNKIARLLALQKELSHTLSHEMRTSLSRLNFTLAILDRDNLEECRDTLQEDIDEL
NTLVKEYLDFSRLEHLTPKLDLGLLNLTVPIRHYIGLLGQYSDKHIEFHELCTTPIAADERLMARAIKNLIDNAIKYSAS
KVLIRCSSTEQGVCVLIEDDGEGLLTDKIDELFMPYVRSGAGRNLPGYGLGLAITRKIVDWHGGTIEAGRSDSLGGACFK
LVLPVSVPTQVN
>Mature_412_residues
MLTRFLGYYALVVLVTFAVIFIGDYSFQRYQQRAEVQVDLHYLFELADDYCRSQVCQPHTSLPFSQLSLIDTRSIQMPAE
SWQRLATGEILALSMGEDEIYYRAMTKDMLLQFGPIPAKPHPGWYVTAFYLLLATLILMGLYPLFRDMYRLREVSLRFSK
NRQFESLQLPTSRYFQPVNDAIFWMVNKIARLLALQKELSHTLSHEMRTSLSRLNFTLAILDRDNLEECRDTLQEDIDEL
NTLVKEYLDFSRLEHLTPKLDLGLLNLTVPIRHYIGLLGQYSDKHIEFHELCTTPIAADERLMARAIKNLIDNAIKYSAS
KVLIRCSSTEQGVCVLIEDDGEGLLTDKIDELFMPYVRSGAGRNLPGYGLGLAITRKIVDWHGGTIEAGRSDSLGGACFK
LVLPVSVPTQVN

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=344, Percent_Identity=29.9418604651163, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789808, Length=299, Percent_Identity=25.752508361204, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=29.8245614035088, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=33.0316742081448, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=25, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=235, Percent_Identity=26.8085106382979, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788279, Length=314, Percent_Identity=23.8853503184713, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47067; Mature: 47067

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRFLGYYALVVLVTFAVIFIGDYSFQRYQQRAEVQVDLHYLFELADDYCRSQVCQPHT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLPFSQLSLIDTRSIQMPAESWQRLATGEILALSMGEDEIYYRAMTKDMLLQFGPIPAKP
CCCHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
HPGWYVTAFYLLLATLILMGLYPLFRDMYRLREVSLRFSKNRQFESLQLPTSRYFQPVND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHH
AIFWMVNKIARLLALQKELSHTLSHEMRTSLSRLNFTLAILDRDNLEECRDTLQEDIDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHH
NTLVKEYLDFSRLEHLTPKLDLGLLNLTVPIRHYIGLLGQYSDKHIEFHELCTTPIAADE
HHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCCHH
RLMARAIKNLIDNAIKYSASKVLIRCSSTEQGVCVLIEDDGEGLLTDKIDELFMPYVRSG
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
AGRNLPGYGLGLAITRKIVDWHGGTIEAGRSDSLGGACFKLVLPVSVPTQVN
CCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHEECCCCCCCCC
>Mature Secondary Structure
MLTRFLGYYALVVLVTFAVIFIGDYSFQRYQQRAEVQVDLHYLFELADDYCRSQVCQPHT
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLPFSQLSLIDTRSIQMPAESWQRLATGEILALSMGEDEIYYRAMTKDMLLQFGPIPAKP
CCCHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCC
HPGWYVTAFYLLLATLILMGLYPLFRDMYRLREVSLRFSKNRQFESLQLPTSRYFQPVND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCHHH
AIFWMVNKIARLLALQKELSHTLSHEMRTSLSRLNFTLAILDRDNLEECRDTLQEDIDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHH
NTLVKEYLDFSRLEHLTPKLDLGLLNLTVPIRHYIGLLGQYSDKHIEFHELCTTPIAADE
HHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCCHH
RLMARAIKNLIDNAIKYSASKVLIRCSSTEQGVCVLIEDDGEGLLTDKIDELFMPYVRSG
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCC
AGRNLPGYGLGLAITRKIVDWHGGTIEAGRSDSLGGACFKLVLPVSVPTQVN
CCCCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]