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The map label for this gene is ygjG [C]

Identifier: 119775781

GI number: 119775781

Start: 3174516

End: 3175856

Strand: Direct

Name: ygjG [C]

Synonym: Sama_2649

Alternate gene names: 119775781

Gene position: 3174516-3175856 (Clockwise)

Preceding gene: 119775779

Following gene: 119775782

Centisome position: 73.72

GC content: 55.93

Gene sequence:

>1341_bases
ATGGTCGACTTCAACGCAACTACAGGACAAGACACACCGTCCCTTGAGCACTACTGGATGCCGTTCACCGCGAACCGCCA
GTTCAAAGCCAGCCCACGATTGCTGGCCAGCGCAGAGGGTATGTTTTACAAAGATGTTGATGGCAATCCGGTACTCGATT
CCACCGCAGGCCTTTGGTGTTGTAACGCCGGCCACGGCAGAAAGAAAATCAGTGAAGCCGTCAGCCACCAAATTCGGGAA
CTGGATTACGCCCCATCATTTCAAATGGGTCATCCACTGGCATTCGAACTGGCCAGTCGCCTTGCCGACATAGCACCGGC
GGGACTGAATCGCATCTTCTTTACCAACTCAGGCAGTGAATCTGTCGACACGGCGCTGAAAATGGCGTTGGCCTACCACA
GGGCTAATGGTCAACCTACCCGAACCCGCTTTATTGGCCGTGAACTTGGCTATCACGGTGTCGGTTTCGGTGGCATCTCC
GTGGGCGGCATCGGTAACAACCGCCGCACTTTCAGCCAGCAACTGCTGCAGGGCGTCGACCACCTGCCCCACACGCTGGA
TATCGCCAACAACGCCTTTTCCCGCGGATTTCCCGCCCATGGCCTCGAAAAAGCCGAAGTGCTGGAGCAGCTCATTACCC
TCCACGGCGCTGAAAACATTGCCGCCGTTATCGTTGAGCCCATGTCCGGCTCCGCTGGCGTGATATTGCCGCCTCAGGGT
TACCTAAAACGTCTGCGCGACATTACCAAGAAACATGGCATCCTGCTGATTTTTGATGAAGTCATCACAGGTTTTGGCCG
TGTTGGTGACGCTTTTGCCAGTCAGCGCTGGGGCGTTGTGCCCGATTTGATGACCACCGCCAAGGCGCTGAACAACGGTG
CCATTCCCATGGGCGCAGTGTTTGTGAGCCAGGATGTACACGATGCCTGCATGACTGGCCCGGAAGAACTGATTGAATTT
TTCCACGGCTACACCTATTCCGGTCATCCGGTGGCTGCAGCCGCGGCATTGGCCACCCTGGATATTTACCAGGAAGAAAA
ACTGTTTGAGCGTACCAAAGAGCTTGAAGGCTACTGGGAAGATGCAGTGCACAGTCTAAGAGACCTGCCGAATGTGATTG
ATATCCGCAACACAGGTTTGGTCGCCGGGGTGCAACTGTCCCCCAATGATGAAGGCCCGGGACGCCGGGGTTACAAGGTG
TTCGAGCGCTGCTTCAGAAACGGCACCCTGGTGCGGGTGACAGGCGACATCATCGCCATGTCTCCACCACTCATCGTGGA
AAAGCAGCACATCGACCAGATAGTTAACACCCTCGGCGATGCCATTCGCGCCGTTGGATGA

Upstream 100 bases:

>100_bases
ATGCACAAAGGTATTCCATGTTCATTATTTCTGACATAGCATAGCGAATATTAACCACCTTAAAAACTCAAACAACCGAT
AGGATCAAGGTAAATAATGT

Downstream 100 bases:

>100_bases
CCCTTTGTCAGCACAGAATTAACAGGTAGCCAAAGATATCCATGCAAAGCATTACTCATTTTGTAAATGGCCAGCACACG
GCCCCCAGTGCCCGCACCCA

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MVDFNATTGQDTPSLEHYWMPFTANRQFKASPRLLASAEGMFYKDVDGNPVLDSTAGLWCCNAGHGRKKISEAVSHQIRE
LDYAPSFQMGHPLAFELASRLADIAPAGLNRIFFTNSGSESVDTALKMALAYHRANGQPTRTRFIGRELGYHGVGFGGIS
VGGIGNNRRTFSQQLLQGVDHLPHTLDIANNAFSRGFPAHGLEKAEVLEQLITLHGAENIAAVIVEPMSGSAGVILPPQG
YLKRLRDITKKHGILLIFDEVITGFGRVGDAFASQRWGVVPDLMTTAKALNNGAIPMGAVFVSQDVHDACMTGPEELIEF
FHGYTYSGHPVAAAAALATLDIYQEEKLFERTKELEGYWEDAVHSLRDLPNVIDIRNTGLVAGVQLSPNDEGPGRRGYKV
FERCFRNGTLVRVTGDIIAMSPPLIVEKQHIDQIVNTLGDAIRAVG

Sequences:

>Translated_446_residues
MVDFNATTGQDTPSLEHYWMPFTANRQFKASPRLLASAEGMFYKDVDGNPVLDSTAGLWCCNAGHGRKKISEAVSHQIRE
LDYAPSFQMGHPLAFELASRLADIAPAGLNRIFFTNSGSESVDTALKMALAYHRANGQPTRTRFIGRELGYHGVGFGGIS
VGGIGNNRRTFSQQLLQGVDHLPHTLDIANNAFSRGFPAHGLEKAEVLEQLITLHGAENIAAVIVEPMSGSAGVILPPQG
YLKRLRDITKKHGILLIFDEVITGFGRVGDAFASQRWGVVPDLMTTAKALNNGAIPMGAVFVSQDVHDACMTGPEELIEF
FHGYTYSGHPVAAAAALATLDIYQEEKLFERTKELEGYWEDAVHSLRDLPNVIDIRNTGLVAGVQLSPNDEGPGRRGYKV
FERCFRNGTLVRVTGDIIAMSPPLIVEKQHIDQIVNTLGDAIRAVG
>Mature_446_residues
MVDFNATTGQDTPSLEHYWMPFTANRQFKASPRLLASAEGMFYKDVDGNPVLDSTAGLWCCNAGHGRKKISEAVSHQIRE
LDYAPSFQMGHPLAFELASRLADIAPAGLNRIFFTNSGSESVDTALKMALAYHRANGQPTRTRFIGRELGYHGVGFGGIS
VGGIGNNRRTFSQQLLQGVDHLPHTLDIANNAFSRGFPAHGLEKAEVLEQLITLHGAENIAAVIVEPMSGSAGVILPPQG
YLKRLRDITKKHGILLIFDEVITGFGRVGDAFASQRWGVVPDLMTTAKALNNGAIPMGAVFVSQDVHDACMTGPEELIEF
FHGYTYSGHPVAAAAALATLDIYQEEKLFERTKELEGYWEDAVHSLRDLPNVIDIRNTGLVAGVQLSPNDEGPGRRGYKV
FERCFRNGTLVRVTGDIIAMSPPLIVEKQHIDQIVNTLGDAIRAVG

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=447, Percent_Identity=27.2930648769575, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4557809, Length=418, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=26.2557077625571, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI226442705, Length=438, Percent_Identity=26.4840182648402, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI284507298, Length=227, Percent_Identity=32.5991189427313, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI226442709, Length=402, Percent_Identity=26.865671641791, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI24119277, Length=445, Percent_Identity=26.0674157303371, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI145693181, Length=407, Percent_Identity=30.958230958231, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786991, Length=429, Percent_Identity=30.3030303030303, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=26.6009852216749, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789759, Length=403, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=28.0182232346241, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789016, Length=417, Percent_Identity=25.6594724220624, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786349, Length=350, Percent_Identity=29.7142857142857, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=28.0182232346241, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=428, Percent_Identity=28.5046728971963, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=35.6223175965665, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71992977, Length=441, Percent_Identity=26.3038548752834, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=441, Percent_Identity=23.1292517006803, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=25.635103926097, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324386, Length=407, Percent_Identity=28.2555282555283, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=26.5700483091787, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=27.7404921700224, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21357415, Length=427, Percent_Identity=27.4004683840749, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=27.5784753363229, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356575, Length=433, Percent_Identity=25.635103926097, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48565; Mature: 48565

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFNATTGQDTPSLEHYWMPFTANRQFKASPRLLASAEGMFYKDVDGNPVLDSTAGLWC
CCCCCCCCCCCCCCCCEEECCEECCCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCCEEE
CNAGHGRKKISEAVSHQIRELDYAPSFQMGHPLAFELASRLADIAPAGLNRIFFTNSGSE
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCH
SVDTALKMALAYHRANGQPTRTRFIGRELGYHGVGFGGISVGGIGNNRRTFSQQLLQGVD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
HLPHTLDIANNAFSRGFPAHGLEKAEVLEQLITLHGAENIAAVIVEPMSGSAGVILPPQG
HCCCHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHH
YLKRLRDITKKHGILLIFDEVITGFGRVGDAFASQRWGVVPDLMTTAKALNNGAIPMGAV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHE
FVSQDVHDACMTGPEELIEFFHGYTYSGHPVAAAAALATLDIYQEEKLFERTKELEGYWE
EECCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVHSLRDLPNVIDIRNTGLVAGVQLSPNDEGPGRRGYKVFERCFRNGTLVRVTGDIIAM
HHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCEEEE
SPPLIVEKQHIDQIVNTLGDAIRAVG
CCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVDFNATTGQDTPSLEHYWMPFTANRQFKASPRLLASAEGMFYKDVDGNPVLDSTAGLWC
CCCCCCCCCCCCCCCCEEECCEECCCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCCEEE
CNAGHGRKKISEAVSHQIRELDYAPSFQMGHPLAFELASRLADIAPAGLNRIFFTNSGSE
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCH
SVDTALKMALAYHRANGQPTRTRFIGRELGYHGVGFGGISVGGIGNNRRTFSQQLLQGVD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHH
HLPHTLDIANNAFSRGFPAHGLEKAEVLEQLITLHGAENIAAVIVEPMSGSAGVILPPQG
HCCCHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECCHH
YLKRLRDITKKHGILLIFDEVITGFGRVGDAFASQRWGVVPDLMTTAKALNNGAIPMGAV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHE
FVSQDVHDACMTGPEELIEFFHGYTYSGHPVAAAAALATLDIYQEEKLFERTKELEGYWE
EECCCHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAVHSLRDLPNVIDIRNTGLVAGVQLSPNDEGPGRRGYKVFERCFRNGTLVRVTGDIIAM
HHHHHHHCCCCCEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEEECCEEEE
SPPLIVEKQHIDQIVNTLGDAIRAVG
CCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]