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The map label for this gene is hlyB [H]

Identifier: 119775739

GI number: 119775739

Start: 3121171

End: 3122796

Strand: Direct

Name: hlyB [H]

Synonym: Sama_2607

Alternate gene names: 119775739

Gene position: 3121171-3122796 (Clockwise)

Preceding gene: 119775738

Following gene: 119775742

Centisome position: 72.48

GC content: 50.68

Gene sequence:

>1626_bases
ATGAATCAGTTGCAAATTAAACACAAGATGCTGCTGGGATTTTTTATTCCGGTATTGCTGCTCATCATCGTTTGCGGCGT
CTCCATGAGTATCATGTCGAAAATAGAAGATGGTGTGCTTCGCATCTATAACGACAGAGTCGTTCCTCTGGAAGATCTCA
AGCTTATTGGTGATGACTATGCCGTTTCTGTCATCGATGCCATCAATAAAGCCAATGCCGGAGGCTTTTCGGCGGAAGAG
GCCAGAAATGGTCTGATAGAAGCTAAAAAGAATATAGCCAGCCGCTGGGACAAGTATATGTCCACAGAACTCACCGCTGA
CGAGCAAAAACTGGCCAGCCAAACCCAGCAGTTATTTGCACCTGCCAATCAGCAGATCCAACTATTGATTGATAAACTCA
GTGGCAAGTCAGGCAGTGTGACCGGACAATTCAGTGCGGATATTATCCCGCTTTACCAGGTAATAGACCCCATCAGCGGC
AAAGTCGCCGAGCTCGTCACTCTGCAAATCCATATCGCTGATCTGGAGCGGGAACAGGTAGAAACATTACATTCGAGCTC
ACTCAAATGGTTTATCGGGCTGGCCGTCTTTGCCGTTCTCATCACCAGTTTTTTCGGTGTCTGGGTCAATCGAGGAGTAA
TGACACCCGTAACCGAAATTCGCCAAAAGCTTAGGCAGATTCGGGAAAAATCCGATATGACAGTCAGCTTTACCGTATTC
CGCGATGATGAGCTGGGCCATATCGCAAAAGATCTGAATGGCGTGGTGAACCACCTCAAAGGCATTTTAAAGAACATTGC
CGAGGCCGCATCGACATTGGGTGATTCTGCCGATGAGCTGAATGAGTTTACACGACAAGCCAATGACCGGATGTTCAAAC
AGCAATCCGAAACCGAACAGACTGCCACCGCCATGAATGAGATGACTGCCGCCGTTGCCGAGGTAGCCCAAAGCAGCAAC
TCAGCAGCAGAATCCGCCAGAAATGCCGATGAAAGTGCAGCCAGAGGCAACAGCATAGTACAGCAGTCCATCAGCAGCAT
GTCGGTGCTCGCGTCACAGATTCAAGGAACGGCCGCCGTGATAGGCGAACTCGCCACCGAGAGCCAAAACATAGGACGGG
TTCTGGATGTAATTAAGAGCATTGCCGAACAGACCAACCTGCTGGCCCTGAACGCCGCTATCGAGGCAGCCCGGGCGGGA
GAACAAGGACGAGGATTTGCCGTGGTGGCCGATGAAGTCAGAACCCTGGCGCAGCGTACCAGCGAATCGACCCGCGAAAT
CGAATCTATGATTGAATCGTTGCAGCAAGGGGTGAAAAGCGCTGTTAACTCCATGGAACAAGGTATTGCCCAGGTAGACA
ATGCCAACGAGAGTACCAACGCCGCCGGCAGCGCACTGCAGGACATAGTGGCGAGTGTCGATAGTATTACCCAACTAAAT
ACCCACATAGCCACAGCCGCCGACGAGCAAAGCTGCGTCGCAGAAAGCATCAATCAGAGCATCATCGCCATCAGTGACAT
AGCCCAGGAATCGACTCAGGCAGCAAACGATTTGAGTGAGGCTGTTCATCAACTTGCACAACTTGCAGGACACATGCGTA
CCCAGGTGGGGACTTTTATTCTTTAG

Upstream 100 bases:

>100_bases
CGAAAAATACCTCCGTTTGCTATACCTATAGCTATGGCTCAACCAAAGGCATGACAGAGTCAGGCAAAGGAGAGTCCATT
TTCCCTGTCGGGGGTCACCG

Downstream 100 bases:

>100_bases
TCACCGGGAGCTATCAGGCTAAAGTGGCTGGATCAGACGGTGTGCATAGAAAACACACTGTCTGATATTGCAACTCTCTA
AACCACATATTGCCCTCACC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MNQLQIKHKMLLGFFIPVLLLIIVCGVSMSIMSKIEDGVLRIYNDRVVPLEDLKLIGDDYAVSVIDAINKANAGGFSAEE
ARNGLIEAKKNIASRWDKYMSTELTADEQKLASQTQQLFAPANQQIQLLIDKLSGKSGSVTGQFSADIIPLYQVIDPISG
KVAELVTLQIHIADLEREQVETLHSSSLKWFIGLAVFAVLITSFFGVWVNRGVMTPVTEIRQKLRQIREKSDMTVSFTVF
RDDELGHIAKDLNGVVNHLKGILKNIAEAASTLGDSADELNEFTRQANDRMFKQQSETEQTATAMNEMTAAVAEVAQSSN
SAAESARNADESAARGNSIVQQSISSMSVLASQIQGTAAVIGELATESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTSESTREIESMIESLQQGVKSAVNSMEQGIAQVDNANESTNAAGSALQDIVASVDSITQLN
THIATAADEQSCVAESINQSIIAISDIAQESTQAANDLSEAVHQLAQLAGHMRTQVGTFIL

Sequences:

>Translated_541_residues
MNQLQIKHKMLLGFFIPVLLLIIVCGVSMSIMSKIEDGVLRIYNDRVVPLEDLKLIGDDYAVSVIDAINKANAGGFSAEE
ARNGLIEAKKNIASRWDKYMSTELTADEQKLASQTQQLFAPANQQIQLLIDKLSGKSGSVTGQFSADIIPLYQVIDPISG
KVAELVTLQIHIADLEREQVETLHSSSLKWFIGLAVFAVLITSFFGVWVNRGVMTPVTEIRQKLRQIREKSDMTVSFTVF
RDDELGHIAKDLNGVVNHLKGILKNIAEAASTLGDSADELNEFTRQANDRMFKQQSETEQTATAMNEMTAAVAEVAQSSN
SAAESARNADESAARGNSIVQQSISSMSVLASQIQGTAAVIGELATESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTSESTREIESMIESLQQGVKSAVNSMEQGIAQVDNANESTNAAGSALQDIVASVDSITQLN
THIATAADEQSCVAESINQSIIAISDIAQESTQAANDLSEAVHQLAQLAGHMRTQVGTFIL
>Mature_541_residues
MNQLQIKHKMLLGFFIPVLLLIIVCGVSMSIMSKIEDGVLRIYNDRVVPLEDLKLIGDDYAVSVIDAINKANAGGFSAEE
ARNGLIEAKKNIASRWDKYMSTELTADEQKLASQTQQLFAPANQQIQLLIDKLSGKSGSVTGQFSADIIPLYQVIDPISG
KVAELVTLQIHIADLEREQVETLHSSSLKWFIGLAVFAVLITSFFGVWVNRGVMTPVTEIRQKLRQIREKSDMTVSFTVF
RDDELGHIAKDLNGVVNHLKGILKNIAEAASTLGDSADELNEFTRQANDRMFKQQSETEQTATAMNEMTAAVAEVAQSSN
SAAESARNADESAARGNSIVQQSISSMSVLASQIQGTAAVIGELATESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAG
EQGRGFAVVADEVRTLAQRTSESTREIESMIESLQQGVKSAVNSMEQGIAQVDNANESTNAAGSALQDIVASVDSITQLN
THIATAADEQSCVAESINQSIIAISDIAQESTQAANDLSEAVHQLAQLAGHMRTQVGTFIL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=31.6715542521994, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1788194, Length=351, Percent_Identity=31.6239316239316, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1787690, Length=404, Percent_Identity=28.7128712871287, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=30.6709265175719, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1789453, Length=342, Percent_Identity=28.3625730994152, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58260; Mature: 58260

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLQIKHKMLLGFFIPVLLLIIVCGVSMSIMSKIEDGVLRIYNDRVVPLEDLKLIGDDY
CCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHH
AVSVIDAINKANAGGFSAEEARNGLIEAKKNIASRWDKYMSTELTADEQKLASQTQQLFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
PANQQIQLLIDKLSGKSGSVTGQFSADIIPLYQVIDPISGKVAELVTLQIHIADLEREQV
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHEEHHHHHHHHHH
ETLHSSSLKWFIGLAVFAVLITSFFGVWVNRGVMTPVTEIRQKLRQIREKSDMTVSFTVF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
RDDELGHIAKDLNGVVNHLKGILKNIAEAASTLGDSADELNEFTRQANDRMFKQQSETEQ
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTAAVAEVAQSSNSAAESARNADESAARGNSIVQQSISSMSVLASQIQGTAAV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IGELATESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
SESTREIESMIESLQQGVKSAVNSMEQGIAQVDNANESTNAAGSALQDIVASVDSITQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
THIATAADEQSCVAESINQSIIAISDIAQESTQAANDLSEAVHQLAQLAGHMRTQVGTFI
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure
MNQLQIKHKMLLGFFIPVLLLIIVCGVSMSIMSKIEDGVLRIYNDRVVPLEDLKLIGDDY
CCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHH
AVSVIDAINKANAGGFSAEEARNGLIEAKKNIASRWDKYMSTELTADEQKLASQTQQLFA
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
PANQQIQLLIDKLSGKSGSVTGQFSADIIPLYQVIDPISGKVAELVTLQIHIADLEREQV
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHEEHHHHHHHHHH
ETLHSSSLKWFIGLAVFAVLITSFFGVWVNRGVMTPVTEIRQKLRQIREKSDMTVSFTVF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEEE
RDDELGHIAKDLNGVVNHLKGILKNIAEAASTLGDSADELNEFTRQANDRMFKQQSETEQ
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TATAMNEMTAAVAEVAQSSNSAAESARNADESAARGNSIVQQSISSMSVLASQIQGTAAV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IGELATESQNIGRVLDVIKSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAQRT
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHH
SESTREIESMIESLQQGVKSAVNSMEQGIAQVDNANESTNAAGSALQDIVASVDSITQLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
THIATAADEQSCVAESINQSIIAISDIAQESTQAANDLSEAVHQLAQLAGHMRTQVGTFI
HHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]