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The map label for this gene is nqrA

Identifier: 119775671

GI number: 119775671

Start: 3047647

End: 3048981

Strand: Reverse

Name: nqrA

Synonym: Sama_2539

Alternate gene names: 119775671

Gene position: 3048981-3047647 (Counterclockwise)

Preceding gene: 119775672

Following gene: 119775670

Centisome position: 70.81

GC content: 52.96

Gene sequence:

>1335_bases
ATGATTACAATTAAGAAAGGATTGGATTTGCCCATTGCGGGTGGTCCAGAGCAAGTTATCCATGATGGCCCAGCCATTAA
ACACGTAGCTACATTGGGTGAAGAGTATATTGGCATGCGTCCTACCATGAGAATCAAGGTAGGCGACAAGGTAGCCAAGG
GTCAGGTGATTTTTGAAGACAAAAAGAATCCTGGCGTTAAATATACGGCTTTGGCCAGTGGTACTGTTACTGAAATCAAC
CGGGGTGCCAAGCGTGTGCTTCAGTCTGTGGTGATCGAAATTGAAGGTAACGATGCCGTTGCTTTTGATAAGTTCGATGC
CAGCCAGCTGGACAGCTTGAGTGCCGAGCAAGTAAGAAACAACCTGATTGAATCAGGTATGTGGACCGCCCTGCGTACCC
GTCCTTTCAGCAAGGTGCCTGCAGTGGACGCGTCTCCTGCCGGTATCTTCGTTACCGCCATCGATACCAACCCCCATGCC
GCCAATCCCGCTCTGGTGATTGCCGGGCATAAAGACGATTTTGCCAATGGCCTTAAGGTGCTGGCGAAACTGACTGAGGG
CAAGGTTTATCTGTGTAAGGCGCCAGGTGCCGATATTCCAGCTGCTAATGCCGAAGTGCATGAGTTTGGTGGTGTACACC
CAGCTGGCCTGCCAGGTACCCATATCCACTTTATTCTGCCTGCGTCCGTAACGCGCACTGTGTGGCATGTTGGCTATCAG
GATGTGATCGCCATCGGCCAACTGTTTACCACGGGTGAACTGAACAACAACCGCGTTATCGCCATCGCCGGCCCGAAAGC
CGTTAAGCCTCGTCTGGTGCGTACTCTGCTGGGTGCCAGCATTGAGACCCTGACAACCGGTGAAGTGGCTGAAGGCAAAG
TGCGCAAGGTGTCTGGTTCTGTGCTGCATGGCCGCACTGCCACTGGTCCTCATGCCTACCTGGGTCGTTATCATCTGCAG
GTTAGCCTGTTGGAAGAAGATACTGAGAAAGAGTTCATTGGCTGGATTTTGCCTGGCTCAAACAAGTTCTCCATTACCCG
TGCCTTCCTGGGTCACCTGTCCCCAAGACGTCTGTTCAACATGACCACCAGTACTGGCGGTTCTGATCGTGCCATGGTGC
CAATTGGCAACTACGAGCGTGTGATGCCACTGGATATTCTGCCAACCATGCTGTTGCGCGACCTGGTATCCGGTGATGTT
GACGGCGCTGTTGCCCTGGGTGCACTGGAGCTGGATGAAGAAGATTTGGCACTGTGTACCTTTGTATGCCCAGGCAAGTA
TGACTACGGTTCCTATCTGCGCGGCTGCCTGGATACGGTTGAGAGGGAAGGCTGA

Upstream 100 bases:

>100_bases
ATAAATCTGCGCCAGCTCAACGCGAACGGTGTTGTTTAAAACCGGGTGCCCCGCAGGAACGCGGCGCTTTGTCTTTCCTT
CAAACGTAGTGCATGTGGAT

Downstream 100 bases:

>100_bases
TGAGCTTGAAAGATTTTCTTGAGCGTATTGAACCGCAATTTGAAAAAGGCGGTAAATACGAGAAGTGGTATGCCCTGTAT
GAAGCGGCCGCCACTATTTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFEDKKNPGVKYTALASGTVTEIN
RGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRNNLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHA
ANPALVIAGHKDDFANGLKVLAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQ
DVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGSVLHGRTATGPHAYLGRYHLQ
VSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDV
DGAVALGALELDEEDLALCTFVCPGKYDYGSYLRGCLDTVEREG

Sequences:

>Translated_444_residues
MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFEDKKNPGVKYTALASGTVTEIN
RGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRNNLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHA
ANPALVIAGHKDDFANGLKVLAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQ
DVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGSVLHGRTATGPHAYLGRYHLQ
VSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDV
DGAVALGALELDEEDLALCTFVCPGKYDYGSYLRGCLDTVEREG
>Mature_444_residues
MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFEDKKNPGVKYTALASGTVTEIN
RGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRNNLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHA
ANPALVIAGHKDDFANGLKVLAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQ
DVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGSVLHGRTATGPHAYLGRYHLQ
VSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFNMTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDV
DGAVALGALELDEEDLALCTFVCPGKYDYGSYLRGCLDTVEREG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_SHEAM (A1S8N5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928411.1
- STRING:   A1S8N5
- GeneID:   4604786
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2539
- NMPDR:   fig|326297.7.peg.2379
- eggNOG:   COG1726
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 47569; Mature: 47569

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEECCEEEEEC
KKNPGVKYTALASGTVTEINRGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRN
CCCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHCCCHHHHHH
NLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHAANPALVIAGHKDDFANGLKV
HHHHCCCHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHH
LAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHCCHH
DVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGS
HHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEECCC
VLHGRTATGPHAYLGRYHLQVSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFN
EEECCCCCCCHHHHEEEEEEEEEECCCCCCCEEEEEECCCCCEEHHHHHHHCCCHHHEEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDVDGAVALGALELDEEDLALCT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRGCLDTVEREG
EECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGGPEQVIHDGPAIKHVATLGEEYIGMRPTMRIKVGDKVAKGQVIFED
CEEECCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCEEECCEEEEEC
KKNPGVKYTALASGTVTEINRGAKRVLQSVVIEIEGNDAVAFDKFDASQLDSLSAEQVRN
CCCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHCCCHHHHHH
NLIESGMWTALRTRPFSKVPAVDASPAGIFVTAIDTNPHAANPALVIAGHKDDFANGLKV
HHHHCCCHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEECCCHHHHHHHH
LAKLTEGKVYLCKAPGADIPAANAEVHEFGGVHPAGLPGTHIHFILPASVTRTVWHVGYQ
HHHHCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEEECCHHHHHHHHCCHH
DVIAIGQLFTTGELNNNRVIAIAGPKAVKPRLVRTLLGASIETLTTGEVAEGKVRKVSGS
HHHHHHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEECCC
VLHGRTATGPHAYLGRYHLQVSLLEEDTEKEFIGWILPGSNKFSITRAFLGHLSPRRLFN
EEECCCCCCCHHHHEEEEEEEEEECCCCCCCEEEEEECCCCCEEHHHHHHHCCCHHHEEE
MTTSTGGSDRAMVPIGNYERVMPLDILPTMLLRDLVSGDVDGAVALGALELDEEDLALCT
EECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCEEEEE
FVCPGKYDYGSYLRGCLDTVEREG
EECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA