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The map label for this gene is dapB

Identifier: 119775637

GI number: 119775637

Start: 3010504

End: 3011316

Strand: Reverse

Name: dapB

Synonym: Sama_2505

Alternate gene names: 119775637

Gene position: 3011316-3010504 (Counterclockwise)

Preceding gene: 119775638

Following gene: 119775636

Centisome position: 69.93

GC content: 55.1

Gene sequence:

>813_bases
ATGACAGGACAAGTAAGGGTAGCCGTGATTGGCGCCAGCGGTCGTATGGGCCGTGCACTGCTTGAAGCTTGTGACAATCA
TGACGGCATCGTCCTTGGCGCCGCCATTGAGCGTGCCGGTTCGACCCTGGTTGGCGTCGACGCCGGTGAAATGGCTGGTA
TTGGTCACCTTGGTCTGGCGTTGGTCGATAATCTGGATGCGGTTGCCGATAAGTTTGATGTTCTTATCGACTTCACTTCA
CCGGAAGGCACTTTGGCCAATCTTGAATGGTGTGCCCGGCAGGGTAAGGCGATAGTCATCGGTACCACCGGCTTTAACCA
TGCGCAAAAAGAGCAGGTAGTGGCTTTTGCCGAAGAAACGCCCGTTGTCATGGCGCCCAACATGTCTGTGGGTGTAAACC
TGATGTGGAAGCTGCTGGAACTGGCGGCCAAAGTCATGGGTGATTACACCGATATCGAAATCATCGAAGGGCACCACAGA
CACAAGAAGGATGCGCCGTCCGGTACCGCACTCAAGATGGGTGAAGTGATTGCCCAGGCTCTGGGGCGCGATCTGGAAAA
AGTGGCCGTCTATGGCCGCGAAGGCATCACAGGTGAACGCGATCGCGAGACCATTGGTTTCGCCACCATACGTGCCGGCG
ATCTGGTGGGTGAGCACACCGCCATGTTTGCCGATATCGGTGAACGACTGGAAATCACCCATAAAGCATCCAGCCGTATG
ACCTTTGCCAACGGCGCCATGCGTGCCGCCAAATGGCTTGCTGAACAAAAACCTGGTCTTTACGACATGCAACAGGTGTT
GGGACTTAATTGA

Upstream 100 bases:

>100_bases
CTTACTCAACCCTGATCTTTGAGGTTGAGCTGCTGGATATCGTTTGATCTGAAACGCCTGAGCAATGCTCGGGCGTTTTT
TTGCAATCAGGGAGCAAGAA

Downstream 100 bases:

>100_bases
TCGAAAAAACCGCCGTTAGGCGGTTTTTTTTAGGTTGGTTGCCCCGAATGTATAGACGAAATGCAGGTTTTCCTATAAAA
TCATCGGAATTTGTCAAAAT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTGQVRVAVIGASGRMGRALLEACDNHDGIVLGAAIERAGSTLVGVDAGEMAGIGHLGLALVDNLDAVADKFDVLIDFTS
PEGTLANLEWCARQGKAIVIGTTGFNHAQKEQVVAFAEETPVVMAPNMSVGVNLMWKLLELAAKVMGDYTDIEIIEGHHR
HKKDAPSGTALKMGEVIAQALGRDLEKVAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
TFANGAMRAAKWLAEQKPGLYDMQQVLGLN

Sequences:

>Translated_270_residues
MTGQVRVAVIGASGRMGRALLEACDNHDGIVLGAAIERAGSTLVGVDAGEMAGIGHLGLALVDNLDAVADKFDVLIDFTS
PEGTLANLEWCARQGKAIVIGTTGFNHAQKEQVVAFAEETPVVMAPNMSVGVNLMWKLLELAAKVMGDYTDIEIIEGHHR
HKKDAPSGTALKMGEVIAQALGRDLEKVAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
TFANGAMRAAKWLAEQKPGLYDMQQVLGLN
>Mature_269_residues
TGQVRVAVIGASGRMGRALLEACDNHDGIVLGAAIERAGSTLVGVDAGEMAGIGHLGLALVDNLDAVADKFDVLIDFTSP
EGTLANLEWCARQGKAIVIGTTGFNHAQKEQVVAFAEETPVVMAPNMSVGVNLMWKLLELAAKVMGDYTDIEIIEGHHRH
KKDAPSGTALKMGEVIAQALGRDLEKVAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRMT
FANGAMRAAKWLAEQKPGLYDMQQVLGLN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=65.5430711610487, Blast_Score=343, Evalue=6e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_SHEAM (A1S8K1)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928377.1
- ProteinModelPortal:   A1S8K1
- SMR:   A1S8K1
- STRING:   A1S8K1
- GeneID:   4604752
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2505
- NMPDR:   fig|326297.7.peg.2345
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   A1S8K1
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28764; Mature: 28633

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGQVRVAVIGASGRMGRALLEACDNHDGIVLGAAIERAGSTLVGVDAGEMAGIGHLGLA
CCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHCCCEEEECCCCHHCCCHHHHHH
LVDNLDAVADKFDVLIDFTSPEGTLANLEWCARQGKAIVIGTTGFNHAQKEQVVAFAEET
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHEEEECCC
PVVMAPNMSVGVNLMWKLLELAAKVMGDYTDIEIIEGHHRHKKDAPSGTALKMGEVIAQA
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LGRDLEKVAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
HCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEEEEECCCCCE
TFANGAMRAAKWLAEQKPGLYDMQQVLGLN
EEHHHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TGQVRVAVIGASGRMGRALLEACDNHDGIVLGAAIERAGSTLVGVDAGEMAGIGHLGLA
CCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEHHHHHCCCEEEECCCCHHCCCHHHHHH
LVDNLDAVADKFDVLIDFTSPEGTLANLEWCARQGKAIVIGTTGFNHAQKEQVVAFAEET
HHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCEEEEECCCCCCHHHHHHEEEECCC
PVVMAPNMSVGVNLMWKLLELAAKVMGDYTDIEIIEGHHRHKKDAPSGTALKMGEVIAQA
CEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHH
LGRDLEKVAVYGREGITGERDRETIGFATIRAGDLVGEHTAMFADIGERLEITHKASSRM
HCCCHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHEEEEECCCCCE
TFANGAMRAAKWLAEQKPGLYDMQQVLGLN
EEHHHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA