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The map label for this gene is nhaC [H]

Identifier: 119775591

GI number: 119775591

Start: 2964863

End: 2966347

Strand: Direct

Name: nhaC [H]

Synonym: Sama_2457

Alternate gene names: 119775591

Gene position: 2964863-2966347 (Clockwise)

Preceding gene: 119775590

Following gene: 119775594

Centisome position: 68.85

GC content: 55.69

Gene sequence:

>1485_bases
ATGACCTCTCAGAAACAGCCCAGCCTGGTGGATGCGCTCATCCCCGTTGTGGCCTTGATTTCCATGCTCGCCGCCGCCGT
CTACTTTTTCTCCTCAGACAGCTCCTATGGCGCAAACCAGATCGCACTGATAATTGCTGCCTGTCTCGCCATGGTGGTGG
GCATTAAAAATGGCCATTGCTGGAAAGACATCGAAGCAGGCATGGTACACAGCATAGGTGTTGCCACACCGGCCTTGCTT
ATTCTGTTCAGCGTCGGCTCTCTCATCGGCGCCTGGATCCTCTCCGGTACTGTGCCCGCCATGATTTACTACGGTATGCA
GGTGCTGAGTCCCGATTACTTTTATGCCGCCAGCTGTCTGCTGTGTGCCCTTGTAGCCCTGTCCATCGGCAGCTCCTGGA
CGGTGGCCGGCACCCTGGGTATTGCCCTTATCGGGATTGCCCAGGCCGTGGGCCTCAGCCTCGAAATCACAGCCGGCGCC
ATCATCAGCGGTGCTTACTTCGGTGACAAGATGTCCCCCATGTCGGACACAACCAATCTCGCACCGGCTGTCGCCGGTAC
AGATATTTTCAGCCACATTCGCCATATGACCTGGACCACGATCCCAAGTATTCTGCTGGCGCTGCTGATTTTTCTGGTGA
TTGGTTTGTCGGGCGACACTGCCGGTGCAGACACCAATCTCGATGCAACCCTGACGCTATTGTCGGATGAGTTCCATATC
GGCCCACATTTGCTGCTGCCGTTGGCAGTGGTCATCTATCTTGCCTACCGCAAGATGCCCGCCTTTCCCACCGTGATTTT
GGGTACCCTTGCCGGTGTGTTCTGCGCTGCGGTGTTCCAGTTCGATGGCGTGGTGAAGCTGGCAAATGACACCAGTCTGA
GCAGTGCATTGGCATTGATCAAAGGCCTGTGGATTGCCATGTTTAATGGTTACAGCGCCAGCACCGGCAATGAAATGCTC
GACGGCCTGTTAAGCCGTGGAGGCATGTCGGGCATGGTCAACACCGTTTGGCTAATTCTCGCAGCCATGGCTTTTGGCGG
CGTAATGGAAGCAACCGGCTTATTGAACCGACTGCTGCAAAGTATGCTCAGAATGGTAAAAGGCTCATCCAGTTTGGTGA
TAACTACCCTGGGATGCGCCATCGGTGCCAACATCATCACCGGCGATCAGTTTATTGCCATCATTCTGCCCGGCCGTATG
CTGAAGCTGGAGTACACCCGCCACAAGCTGGCGCCTGTTAATCTGTCGAGGGCGCTGGAAGACTCAGCCACGGTCACCAG
TCCACTGGTTCCCTGGAACACCTGCGGCGCCTTTATGGCGAGCACTCTGGGTGTGGCGACCATCGCCTACCTGCCCTTCG
CCTTCTTCAATCTCATCTGCCCCGTGGTAAGCGCGGGTTATGCCTACTTCCAGATAAAACTGTTACCTCTGGAGGAATCC
GATATGTTGGAAAATAGCGACGAGCTTAAAGGCGCCGAAGCCTGA

Upstream 100 bases:

>100_bases
GGCAGGTCAAACACAAGCAAAAGTTAAGAAAAATAAAGCCCATCATGGGCATCCGGCCCACTGCCGGAAATAAGAATTAT
AAAGTTCAGGATGTAAAAAT

Downstream 100 bases:

>100_bases
TTATCGACAGGCTTATAAATCGACAGCAGCAAAAACGCCCTCTTAAGGGCGTTTTTTGTTTGTGCTTACCGGGAACAGGC
TCTGCTGCGGGTCAGCTCCA

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MTSQKQPSLVDALIPVVALISMLAAAVYFFSSDSSYGANQIALIIAACLAMVVGIKNGHCWKDIEAGMVHSIGVATPALL
ILFSVGSLIGAWILSGTVPAMIYYGMQVLSPDYFYAASCLLCALVALSIGSSWTVAGTLGIALIGIAQAVGLSLEITAGA
IISGAYFGDKMSPMSDTTNLAPAVAGTDIFSHIRHMTWTTIPSILLALLIFLVIGLSGDTAGADTNLDATLTLLSDEFHI
GPHLLLPLAVVIYLAYRKMPAFPTVILGTLAGVFCAAVFQFDGVVKLANDTSLSSALALIKGLWIAMFNGYSASTGNEML
DGLLSRGGMSGMVNTVWLILAAMAFGGVMEATGLLNRLLQSMLRMVKGSSSLVITTLGCAIGANIITGDQFIAIILPGRM
LKLEYTRHKLAPVNLSRALEDSATVTSPLVPWNTCGAFMASTLGVATIAYLPFAFFNLICPVVSAGYAYFQIKLLPLEES
DMLENSDELKGAEA

Sequences:

>Translated_494_residues
MTSQKQPSLVDALIPVVALISMLAAAVYFFSSDSSYGANQIALIIAACLAMVVGIKNGHCWKDIEAGMVHSIGVATPALL
ILFSVGSLIGAWILSGTVPAMIYYGMQVLSPDYFYAASCLLCALVALSIGSSWTVAGTLGIALIGIAQAVGLSLEITAGA
IISGAYFGDKMSPMSDTTNLAPAVAGTDIFSHIRHMTWTTIPSILLALLIFLVIGLSGDTAGADTNLDATLTLLSDEFHI
GPHLLLPLAVVIYLAYRKMPAFPTVILGTLAGVFCAAVFQFDGVVKLANDTSLSSALALIKGLWIAMFNGYSASTGNEML
DGLLSRGGMSGMVNTVWLILAAMAFGGVMEATGLLNRLLQSMLRMVKGSSSLVITTLGCAIGANIITGDQFIAIILPGRM
LKLEYTRHKLAPVNLSRALEDSATVTSPLVPWNTCGAFMASTLGVATIAYLPFAFFNLICPVVSAGYAYFQIKLLPLEES
DMLENSDELKGAEA
>Mature_493_residues
TSQKQPSLVDALIPVVALISMLAAAVYFFSSDSSYGANQIALIIAACLAMVVGIKNGHCWKDIEAGMVHSIGVATPALLI
LFSVGSLIGAWILSGTVPAMIYYGMQVLSPDYFYAASCLLCALVALSIGSSWTVAGTLGIALIGIAQAVGLSLEITAGAI
ISGAYFGDKMSPMSDTTNLAPAVAGTDIFSHIRHMTWTTIPSILLALLIFLVIGLSGDTAGADTNLDATLTLLSDEFHIG
PHLLLPLAVVIYLAYRKMPAFPTVILGTLAGVFCAAVFQFDGVVKLANDTSLSSALALIKGLWIAMFNGYSASTGNEMLD
GLLSRGGMSGMVNTVWLILAAMAFGGVMEATGLLNRLLQSMLRMVKGSSSLVITTLGCAIGANIITGDQFIAIILPGRML
KLEYTRHKLAPVNLSRALEDSATVTSPLVPWNTCGAFMASTLGVATIAYLPFAFFNLICPVVSAGYAYFQIKLLPLEESD
MLENSDELKGAEA

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 51806; Mature: 51674

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQKQPSLVDALIPVVALISMLAAAVYFFSSDSSYGANQIALIIAACLAMVVGIKNGHC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
WKDIEAGMVHSIGVATPALLILFSVGSLIGAWILSGTVPAMIYYGMQVLSPDYFYAASCL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHH
LCALVALSIGSSWTVAGTLGIALIGIAQAVGLSLEITAGAIISGAYFGDKMSPMSDTTNL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCHHHCCHHCCCCCCCCCCCCCC
APAVAGTDIFSHIRHMTWTTIPSILLALLIFLVIGLSGDTAGADTNLDATLTLLSDEFHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
GPHLLLPLAVVIYLAYRKMPAFPTVILGTLAGVFCAAVFQFDGVVKLANDTSLSSALALI
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHH
KGLWIAMFNGYSASTGNEMLDGLLSRGGMSGMVNTVWLILAAMAFGGVMEATGLLNRLLQ
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLRMVKGSSSLVITTLGCAIGANIITGDQFIAIILPGRMLKLEYTRHKLAPVNLSRALE
HHHHHHCCCCCEEEEEHHHHHCCCEEECCCEEEEEECCCEEEEEHHHHHCCCCCHHHHHH
DSATVTSPLVPWNTCGAFMASTLGVATIAYLPFAFFNLICPVVSAGYAYFQIKLLPLEES
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHH
DMLENSDELKGAEA
HHHCCCCCCCCCCC
>Mature Secondary Structure 
TSQKQPSLVDALIPVVALISMLAAAVYFFSSDSSYGANQIALIIAACLAMVVGIKNGHC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
WKDIEAGMVHSIGVATPALLILFSVGSLIGAWILSGTVPAMIYYGMQVLSPDYFYAASCL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHH
LCALVALSIGSSWTVAGTLGIALIGIAQAVGLSLEITAGAIISGAYFGDKMSPMSDTTNL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCHHHCCHHCCCCCCCCCCCCCC
APAVAGTDIFSHIRHMTWTTIPSILLALLIFLVIGLSGDTAGADTNLDATLTLLSDEFHI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
GPHLLLPLAVVIYLAYRKMPAFPTVILGTLAGVFCAAVFQFDGVVKLANDTSLSSALALI
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHH
KGLWIAMFNGYSASTGNEMLDGLLSRGGMSGMVNTVWLILAAMAFGGVMEATGLLNRLLQ
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLRMVKGSSSLVITTLGCAIGANIITGDQFIAIILPGRMLKLEYTRHKLAPVNLSRALE
HHHHHHCCCCCEEEEEHHHHHCCCEEECCCEEEEEECCCEEEEEHHHHHCCCCCHHHHHH
DSATVTSPLVPWNTCGAFMASTLGVATIAYLPFAFFNLICPVVSAGYAYFQIKLLPLEES
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHH
DMLENSDELKGAEA
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]