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The map label for this gene is dtpA [H]

Identifier: 119775545

GI number: 119775545

Start: 2897450

End: 2899003

Strand: Reverse

Name: dtpA [H]

Synonym: Sama_2411

Alternate gene names: 119775545

Gene position: 2899003-2897450 (Counterclockwise)

Preceding gene: 119775546

Following gene: 119775543

Centisome position: 67.32

GC content: 53.02

Gene sequence:

>1554_bases
ATGACAACTACAACAGGGCAATGGCCAAAACAAATCCCCTACATTATTGCCTCTGAAGCCTGTGAGCGGTTCAGCTTTTA
TGGCATGCGCAACATTCTCACGCCGTTTTTGATGACGGCACTGCTGCTGTCAGTGCCGGAACATCTCAGGGCCGGCGAAG
CCAAGGATGTGTTTCACTCCTTTGTGATTGGTGTGTACTTCTTTCCACTGTTGGGGGGCTGGATTGGGGACAGGCTCTTT
GGTAAGTACAACACCATCTTGTGGTTGTCGCTGCTTTACTGTGTTGGCCATGCTTTTCTGGCCATTTTTGAGGACAGTAA
AACCGGCTTTTATACCGGCCTGTTTTTGATTGCGCTGGGCTCGGGTGGGATAAAACCCCTGGTGTCCTCTTTTATGGGCG
ACCAATTTGATCAGAGTAACAAGTCATTGGCCCAAAAAGCGTTTGACATGTTTTACTTCACTATCAATTTTGGCTCTTTC
TTCGCCTCTTTGAGTATGCCCTTGCTGCTGAAACATTTCGGTGCTGCGGTTGCCTTTGGTATTCCCGGGGTGCTGATGTT
TATCGCTACCGTCTTTTTCTGGGCGGGGCGTCACCGCTATGTGCATATGCCCCCAGAGCCCAAAAATCCCAACGGTTTTT
TGCCTGTTATCAAAACGGCGTTACTCAGTCCGGGTGCAAATCGTTTTGGTCTGGCGCTGGCGCTGATGGGTACAGTGCTC
GCCGTGATTGCCCTTGGATTTATGCCCTCCCTCGGGCTGGTGACCTCACTGTGTCTGGCGTTGGTACTGCTGATGGGGTT
TGTAGGCAGCGGCGCCTCCATGCAGCTGGACAGAGCCAGGGCACGCCATGGTGATGAGGCTGTGGAGGGCGTCAGGGCGG
TGATGCGGATATTGGTACTCTTTGCCCTGGTTACGCCTTTCTGGTCGCTGTTCGACCAAAAGGCATCCACCTGGATTTTG
CAGGCCAATGAGATGACCAAACCGGAGTGGTTTGAACCGGCCATGATGCAGGCATTGAATCCACTCCTGGTAATGATCCT
TATCCCCTTCAATAACTTTGTGCTGTACCCCACGCTGGAGCGATGGGGATTCAGGTTAACGGCTCTGGGCAAAATGGCGT
CTGGCATCGCCTTTTCCGGCCTGTCCTGGGTGGTAATAGGCAGCATTCAATTGATGATGGATGGCGGCAGCGCCGTTTCG
ATTGTGTGGCAGGTTTTGCCCTATGCGTTGCTTACCTTTGGTGAGGTGTTGGTGTCGGCCACCGGGCTTGAGTTTGCCTA
CAGTCAGGCGCCAAAGACCATGAAGGGCACCATTATGAGTTTCTGGACCCTGTCGGTGACCGTGGGTAACCTCTGGGTGT
TGCTTGCCAATGCCAGTGTGAAGGGGCAGGGCATGACTGATTGGATTGCCGGTACAGGATTGTCGGTGACGGCGTTTCAA
ATGTTCTTTTTTGCGGGCTTCGCTTTGGTGGCCGCAGCCGTGTTTGCCCTGTACGCCAGAAATTATCGAATGCAGGACCA
TTACCGTGAGGCAGCACAAGTCTCAGCGGTCTGA

Upstream 100 bases:

>100_bases
TAGGGTTTTCTTAAGCAACACACACCGACCGGCAGCCCAGTGCATTCCATCTTCAAACCCTGTAGGATTGGGCAATTGGT
GACCAATTTTAAGGGAAGAG

Downstream 100 bases:

>100_bases
ACCTCGGTAAATGGATGAGGAATATCGCCTAACGCGGCATAGAAAACAAAAAACGCAGCCAGATGGCTGCGTTTTTGATA
TTCGGCATTTTACTCGATGA

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MTTTTGQWPKQIPYIIASEACERFSFYGMRNILTPFLMTALLLSVPEHLRAGEAKDVFHSFVIGVYFFPLLGGWIGDRLF
GKYNTILWLSLLYCVGHAFLAIFEDSKTGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSF
FASLSMPLLLKHFGAAVAFGIPGVLMFIATVFFWAGRHRYVHMPPEPKNPNGFLPVIKTALLSPGANRFGLALALMGTVL
AVIALGFMPSLGLVTSLCLALVLLMGFVGSGASMQLDRARARHGDEAVEGVRAVMRILVLFALVTPFWSLFDQKASTWIL
QANEMTKPEWFEPAMMQALNPLLVMILIPFNNFVLYPTLERWGFRLTALGKMASGIAFSGLSWVVIGSIQLMMDGGSAVS
IVWQVLPYALLTFGEVLVSATGLEFAYSQAPKTMKGTIMSFWTLSVTVGNLWVLLANASVKGQGMTDWIAGTGLSVTAFQ
MFFFAGFALVAAAVFALYARNYRMQDHYREAAQVSAV

Sequences:

>Translated_517_residues
MTTTTGQWPKQIPYIIASEACERFSFYGMRNILTPFLMTALLLSVPEHLRAGEAKDVFHSFVIGVYFFPLLGGWIGDRLF
GKYNTILWLSLLYCVGHAFLAIFEDSKTGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSF
FASLSMPLLLKHFGAAVAFGIPGVLMFIATVFFWAGRHRYVHMPPEPKNPNGFLPVIKTALLSPGANRFGLALALMGTVL
AVIALGFMPSLGLVTSLCLALVLLMGFVGSGASMQLDRARARHGDEAVEGVRAVMRILVLFALVTPFWSLFDQKASTWIL
QANEMTKPEWFEPAMMQALNPLLVMILIPFNNFVLYPTLERWGFRLTALGKMASGIAFSGLSWVVIGSIQLMMDGGSAVS
IVWQVLPYALLTFGEVLVSATGLEFAYSQAPKTMKGTIMSFWTLSVTVGNLWVLLANASVKGQGMTDWIAGTGLSVTAFQ
MFFFAGFALVAAAVFALYARNYRMQDHYREAAQVSAV
>Mature_516_residues
TTTTGQWPKQIPYIIASEACERFSFYGMRNILTPFLMTALLLSVPEHLRAGEAKDVFHSFVIGVYFFPLLGGWIGDRLFG
KYNTILWLSLLYCVGHAFLAIFEDSKTGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSFF
ASLSMPLLLKHFGAAVAFGIPGVLMFIATVFFWAGRHRYVHMPPEPKNPNGFLPVIKTALLSPGANRFGLALALMGTVLA
VIALGFMPSLGLVTSLCLALVLLMGFVGSGASMQLDRARARHGDEAVEGVRAVMRILVLFALVTPFWSLFDQKASTWILQ
ANEMTKPEWFEPAMMQALNPLLVMILIPFNNFVLYPTLERWGFRLTALGKMASGIAFSGLSWVVIGSIQLMMDGGSAVSI
VWQVLPYALLTFGEVLVSATGLEFAYSQAPKTMKGTIMSFWTLSVTVGNLWVLLANASVKGQGMTDWIAGTGLSVTAFQM
FFFAGFALVAAAVFALYARNYRMQDHYREAAQVSAV

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=392, Percent_Identity=33.1632653061224, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4827008, Length=420, Percent_Identity=28.5714285714286, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI226371748, Length=384, Percent_Identity=32.03125, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI21717816, Length=561, Percent_Identity=22.8163992869875, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI7706117, Length=422, Percent_Identity=22.9857819905213, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787922, Length=449, Percent_Identity=26.0579064587973, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790572, Length=351, Percent_Identity=28.2051282051282, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786927, Length=384, Percent_Identity=25.5208333333333, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789911, Length=455, Percent_Identity=24.3956043956044, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17569141, Length=411, Percent_Identity=32.360097323601, Blast_Score=188, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI71987453, Length=411, Percent_Identity=32.1167883211679, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17541704, Length=408, Percent_Identity=32.843137254902, Blast_Score=171, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6322946, Length=546, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28571102, Length=431, Percent_Identity=31.7865429234339, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571100, Length=431, Percent_Identity=31.7865429234339, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571098, Length=416, Percent_Identity=32.2115384615385, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24639585, Length=383, Percent_Identity=33.9425587467363, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24639583, Length=383, Percent_Identity=33.9425587467363, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24639581, Length=383, Percent_Identity=33.9425587467363, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24645459, Length=522, Percent_Identity=25.6704980842912, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56745; Mature: 56613

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS01022 PTR2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTGQWPKQIPYIIASEACERFSFYGMRNILTPFLMTALLLSVPEHLRAGEAKDVFHS
CCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHH
FVIGVYFFPLLGGWIGDRLFGKYNTILWLSLLYCVGHAFLAIFEDSKTGFYTGLFLIALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCC
SGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSFFASLSMPLLLKHFGAAVAFG
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHH
IPGVLMFIATVFFWAGRHRYVHMPPEPKNPNGFLPVIKTALLSPGANRFGLALALMGTVL
HHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHH
AVIALGFMPSLGLVTSLCLALVLLMGFVGSGASMQLDRARARHGDEAVEGVRAVMRILVL
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHH
FALVTPFWSLFDQKASTWILQANEMTKPEWFEPAMMQALNPLLVMILIPFNNFVLYPTLE
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHEECCCCEEEEEEHH
RWGFRLTALGKMASGIAFSGLSWVVIGSIQLMMDGGSAVSIVWQVLPYALLTFGEVLVSA
HHCCCHHHHHHHHCCCHHCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
TGLEFAYSQAPKTMKGTIMSFWTLSVTVGNLWVLLANASVKGQGMTDWIAGTGLSVTAFQ
CCCHHHHHHCCCHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCCHHHHHCCCCHHHHHH
MFFFAGFALVAAAVFALYARNYRMQDHYREAAQVSAV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTTGQWPKQIPYIIASEACERFSFYGMRNILTPFLMTALLLSVPEHLRAGEAKDVFHS
CCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHH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HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA