Click here to switch to the map view.

The map label for this gene is aceB [H]

Identifier: 119775515

GI number: 119775515

Start: 2859826

End: 2861457

Strand: Reverse

Name: aceB [H]

Synonym: Sama_2381

Alternate gene names: 119775515

Gene position: 2861457-2859826 (Counterclockwise)

Preceding gene: 119775516

Following gene: 119775514

Centisome position: 66.45

GC content: 54.29

Gene sequence:

>1632_bases
ATGACAGAGCAAATGATGGAGCAGCCACAGACACTGACCGGGCTCAAGCTGGCGGGTCATCATATCCAGGGGCAGGAAGA
AGTCTTTACTGAAGGCGCAATGTCGCTGCTTGAGTCCCTGTGTGCCAGGTTTGCAGGCGACGTGGATGCCTTACTGGCTA
AACGTAAAGAACGCCAGGTTCGCATTGATAAAGGTGAGTTGCCGGATTTCCTGCCGGAGACACGCGCCATACGTGATGGT
AAGTGGACCATTCGTGGCATACCAACCGACTTGCAGGATCGCCGGGTGGAAATCACTGGTCCCGTGGACCGCAAGATGAT
CATCAATGCCCTGAATGCCGATGTGAAAGTCTTTATGGCTGACTTTGAGGATTCATTGGCACCCAGCTGGGAAAAGGTGA
TTCAGGGGCAAATCAACCTGCGTGATGCGGTGCGTGGCACCATTGAATATAAAGCGCCCGATACAGGTAAAGAGTACCGC
TTGAACGATAATCCAGCGGTGCTGATTGCCAGGGTGCGCGGCTTACACCTCAAAGAAAAACACGTGGAATTTAACGGCCA
ATCGATCCCGGGAGCCCTGTTTGATTTCTGTTTCTACTTTTATCACAACTACCGTCAGTTACTGAGTAAAGGCAGTGGGC
CGTACTTTTATATCCCCAAGCTCGAGAGCCATCTCGAGGCGCGTTGGTGGGCCAAGGTCTTTGCCTTTACCGAAGAGCGT
TTCTGCCTCGAGCCGGGCACAATCAAGTGTACCTGTTTGATAGAAACCCTGCCGGCCGTGTTTGAAATGGACGAAATCCT
CTATGAGCTGCGCTCCAATATCGTTGCGCTCAACTGTGGTCGATGGGATTACATCTTCAGCTATATCAAAACCTTGAAAC
ACCACAGTGATCGCGTACTGCCTGACAGGCAACAAGTCACCATGGATAAGCCGTTCCTCAGCGCCTATTCGCGTCTGCTG
ATCAAAACTTGTCACAAGCGGGGAGCCCTTGCGATGGGCGGTATGGCGGCTTTCATTCCAGCCAAAGATGCCGAAGCCAA
CCGCCTGGTGCTTGAACGGGTTTGCAAAGACAAGGAGCTGGAAGCCCGTAACGGCCATGACGGCACCTGGGTCGCCCATC
CCGGTCTGGCACAAACGGCGATGGCCGTGTTTAACCAGTTTATCGGTGATGACCACTGCAATCAGCTGCACATCACCCGT
GATGTGGATGCGCCGATTTTGGCCAGCGAGCTGCTGGCGCCCTGCGAGGGTGAGCGCACCGAGCACGGTATGCGACTGAA
TATTCGCATTGCGCTGCAGTACATCGAGGCCTGGATCAGTGGCAATGGTTGTGTGCCCATTTATGGTCTGATGGAAGATG
CCGCCACGGCGGAAATCTCCCGCGCCTCCATCTGGCAATGGATCCATCATCAGAAGCACCTATCCAACGGCAAACTTGTG
ACCAAGGCACTGCTGAAGGAAATGCTGGTGGAGGAGCTTGCCAACGTCAAAGAAGAAGTGGGCAGCGAGCGCTTTACCCA
CGGCAGATTTACCCAAGCGGCTGTGCTGCTGGAGGAGATCACGACCGCCGACGAGCTGGTCGACTTCCTGACACTGCCGG
GCTACGAGCTGCTGACCAAACAAGAACACTGA

Upstream 100 bases:

>100_bases
GAAACGAACATTTGACGGTTTTTGCTGGCTTGTAATGGCGTGGGAATACGCAATATACAATCCGCAAGCCGCGGGGAAAC
CGACAATCGGGGATAACACC

Downstream 100 bases:

>100_bases
TTAATCCCTGAAAACATAGAACATCTTACCCGTCACATGCGTGACGGGCAGACCCTAACACCCCAAAGGAGAGTCACCAT
GAGCAAGTACATCAGCCGCC

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTEQMMEQPQTLTGLKLAGHHIQGQEEVFTEGAMSLLESLCARFAGDVDALLAKRKERQVRIDKGELPDFLPETRAIRDG
KWTIRGIPTDLQDRRVEITGPVDRKMIINALNADVKVFMADFEDSLAPSWEKVIQGQINLRDAVRGTIEYKAPDTGKEYR
LNDNPAVLIARVRGLHLKEKHVEFNGQSIPGALFDFCFYFYHNYRQLLSKGSGPYFYIPKLESHLEARWWAKVFAFTEER
FCLEPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKHHSDRVLPDRQQVTMDKPFLSAYSRLL
IKTCHKRGALAMGGMAAFIPAKDAEANRLVLERVCKDKELEARNGHDGTWVAHPGLAQTAMAVFNQFIGDDHCNQLHITR
DVDAPILASELLAPCEGERTEHGMRLNIRIALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIHHQKHLSNGKLV
TKALLKEMLVEELANVKEEVGSERFTHGRFTQAAVLLEEITTADELVDFLTLPGYELLTKQEH

Sequences:

>Translated_543_residues
MTEQMMEQPQTLTGLKLAGHHIQGQEEVFTEGAMSLLESLCARFAGDVDALLAKRKERQVRIDKGELPDFLPETRAIRDG
KWTIRGIPTDLQDRRVEITGPVDRKMIINALNADVKVFMADFEDSLAPSWEKVIQGQINLRDAVRGTIEYKAPDTGKEYR
LNDNPAVLIARVRGLHLKEKHVEFNGQSIPGALFDFCFYFYHNYRQLLSKGSGPYFYIPKLESHLEARWWAKVFAFTEER
FCLEPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKHHSDRVLPDRQQVTMDKPFLSAYSRLL
IKTCHKRGALAMGGMAAFIPAKDAEANRLVLERVCKDKELEARNGHDGTWVAHPGLAQTAMAVFNQFIGDDHCNQLHITR
DVDAPILASELLAPCEGERTEHGMRLNIRIALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIHHQKHLSNGKLV
TKALLKEMLVEELANVKEEVGSERFTHGRFTQAAVLLEEITTADELVDFLTLPGYELLTKQEH
>Mature_542_residues
TEQMMEQPQTLTGLKLAGHHIQGQEEVFTEGAMSLLESLCARFAGDVDALLAKRKERQVRIDKGELPDFLPETRAIRDGK
WTIRGIPTDLQDRRVEITGPVDRKMIINALNADVKVFMADFEDSLAPSWEKVIQGQINLRDAVRGTIEYKAPDTGKEYRL
NDNPAVLIARVRGLHLKEKHVEFNGQSIPGALFDFCFYFYHNYRQLLSKGSGPYFYIPKLESHLEARWWAKVFAFTEERF
CLEPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKHHSDRVLPDRQQVTMDKPFLSAYSRLLI
KTCHKRGALAMGGMAAFIPAKDAEANRLVLERVCKDKELEARNGHDGTWVAHPGLAQTAMAVFNQFIGDDHCNQLHITRD
VDAPILASELLAPCEGERTEHGMRLNIRIALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIHHQKHLSNGKLVT
KALLKEMLVEELANVKEEVGSERFTHGRFTQAAVLLEEITTADELVDFLTLPGYELLTKQEH

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=534, Percent_Identity=67.9775280898876, Blast_Score=757, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=530, Percent_Identity=49.0566037735849, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71982926, Length=421, Percent_Identity=50.8313539192399, Blast_Score=405, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6322222, Length=523, Percent_Identity=44.7418738049713, Blast_Score=432, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6324212, Length=520, Percent_Identity=44.0384615384615, Blast_Score=416, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 61682; Mature: 61550

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQMMEQPQTLTGLKLAGHHIQGQEEVFTEGAMSLLESLCARFAGDVDALLAKRKERQV
CCHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
RIDKGELPDFLPETRAIRDGKWTIRGIPTDLQDRRVEITGPVDRKMIINALNADVKVFMA
ECCCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEE
DFEDSLAPSWEKVIQGQINLRDAVRGTIEYKAPDTGKEYRLNDNPAVLIARVRGLHLKEK
CHHHHCCCCHHHHHCCCCCHHHHHCCEEEECCCCCCCCEEECCCCEEEEEEHHCCCEEHH
HVEFNGQSIPGALFDFCFYFYHNYRQLLSKGSGPYFYIPKLESHLEARWWAKVFAFTEER
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
FCLEPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKHHSDRVL
EEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCC
PDRQQVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDAEANRLVLERVCKDKEL
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCHHHHHHHHHCCCCCC
EARNGHDGTWVAHPGLAQTAMAVFNQFIGDDHCNQLHITRDVDAPILASELLAPCEGERT
CCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCC
EHGMRLNIRIALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIHHQKHLSNGKLV
CCCCEEEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TKALLKEMLVEELANVKEEVGSERFTHGRFTQAAVLLEEITTADELVDFLTLPGYELLTK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
QEH
CCC
>Mature Secondary Structure 
TEQMMEQPQTLTGLKLAGHHIQGQEEVFTEGAMSLLESLCARFAGDVDALLAKRKERQV
CHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
RIDKGELPDFLPETRAIRDGKWTIRGIPTDLQDRRVEITGPVDRKMIINALNADVKVFMA
ECCCCCCCCCCCCHHCCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEE
DFEDSLAPSWEKVIQGQINLRDAVRGTIEYKAPDTGKEYRLNDNPAVLIARVRGLHLKEK
CHHHHCCCCHHHHHCCCCCHHHHHCCEEEECCCCCCCCEEECCCCEEEEEEHHCCCEEHH
HVEFNGQSIPGALFDFCFYFYHNYRQLLSKGSGPYFYIPKLESHLEARWWAKVFAFTEER
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
FCLEPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKHHSDRVL
EEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCC
PDRQQVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDAEANRLVLERVCKDKEL
CCCHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCHHHHHHHHHCCCCCC
EARNGHDGTWVAHPGLAQTAMAVFNQFIGDDHCNQLHITRDVDAPILASELLAPCEGERT
CCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCC
EHGMRLNIRIALQYIEAWISGNGCVPIYGLMEDAATAEISRASIWQWIHHQKHLSNGKLV
CCCCEEEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TKALLKEMLVEELANVKEEVGSERFTHGRFTQAAVLLEEITTADELVDFLTLPGYELLTK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
QEH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]