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The map label for this gene is mltF [H]

Identifier: 119775486

GI number: 119775486

Start: 2824025

End: 2825533

Strand: Direct

Name: mltF [H]

Synonym: Sama_2351

Alternate gene names: 119775486

Gene position: 2824025-2825533 (Clockwise)

Preceding gene: 119775480

Following gene: 119775488

Centisome position: 65.58

GC content: 55.0

Gene sequence:

>1509_bases
ATGCATCGGGTAGAATTGCGCCGTTTTCGACCAGTCTTGACTGAATTTCCTGGGGTTAATTTATTGATTAGATTAAGACG
AGTCCTTTTTCTGCTGACGAGTGTACTGGTGCTGACAGCCTGTCAGCCACCAGGCCTTGTTGTGGACGCACCACAACCCA
AAGCAGAAGCCGAGACACTTCGCGTGGGCACCCTGTACGGTGCACAGATCTACATGAGTTCGGGCCAGGGCCTGTCCGGC
TTTGATTATGAGCTGGCCCAGAAGTTTGCCGACTATTTGGGTAAACCTTTGGAAATGCAGCCATACAGCAACAGAAGCGA
GCTTTATGATGCGTTGGCCAAAGGCGAAATTGACCTGATTGCCGCCGGTATCACCGAAAGCCCCAACCGCCGCAATCGTT
TTCGTATGGGACCGCCCCTTTACCGGGTGGACCAGGTAGTGGTGTACCGTCAGGGTAACAGGGCGCCGGAATCCATAGAA
CAGCTCAGCGGCAATCTCACTGTGGTGGCCGATTCGGCGTTTGTGGAAACCCTCACGAGGCTGCAGCAAACCCATACAAA
TCTGAGCTGGGAGCAAACCAGCGAAAAAGACAACGACGAGCTCATTGCCATGATTGCCAGTGGCGAGCTCAATTACACCC
TGGCGCAATCAACCAGTCTGGACATTAACCGCCGCTATATGCCGGAGCTCAGAAGCGGCCTGGTGCTGGAGGAAAAGGTA
CCTGTGGTCTGGCTGTTGCCTGCTCAAAATAGCGATGCCCTGATGAGCAAGCTGCTGGCCTTCTGGCACCAGGAAAAACG
TGCCGGCACCCTGGCCCATCTCAATGAAAAATACTTCGGCCACGTGAAGCGTTTCGATTATGTCGACACCCGCGCTTTTA
TCCGCGCCATCGATGCCAAACTGCCCCGTTACCGGCCTTTGTTTGAAGAATATGCCGGTGATTTGGACTGGCGAAAGCTG
GCCGCAGCCAGTTATCAGGAGTCACACTGGAACCCCAATGCCCGCTCTCCTACCGGGGTACGTGGCATGATGATGCTGAC
CAATGCCACCGCCAGCCAGTTGGGGGTGACCAATCGCCTCGACCCGCGCCAAAGCATCCGTGGTGGCGCCGATTATCTGC
GGGACTTGATAAATCGCCTGCCGGAATCCATCCCCGAAAATCAGCGGATGTGGTTTGCGCTGGCCGCCTACAACATAGGT
TTGGGTCATTTGGAGGATGCACGCAGGCTGGCTGAAGCGCAGGGGCTAAATCCCAGCGCCTGGCGGGATGTGAAACAGGT
ATTGCCATTGCTGCAAAAAAGGAAGTTTTACAGCCAAACCCGTTATGGTTATGCCAGAGGCGGTGAAGCTGTGCACTATG
TGGACTCCATCCGCCGCTATTACGACACTCTGGTTTGGGTCGACAATCAAAAACCCAAAGATGAGCCACAGCTTCCGGAT
GAAATTCAGGTAGAAGAAACCGCCGCCAGCAGTGGCGCAGAGCCACCAACCGCGGCTCCCCGCGAATAA

Upstream 100 bases:

>100_bases
CCCCGTAAATCACCTGCCATGCTTACTCAAAACAGTGTTTCCTGTAATATTGGGTTCCGGTTCTGGCACGGATTGCCGGA
CTGTTCAGCAAGGGCTCAGG

Downstream 100 bases:

>100_bases
CCCCTTTACTGATGAACAGAATTTCACCACCGCGACTGTGGCTGTGATCCCCTGCTCTTGCCAGTATCACAGACCACTGC
TAATGTGCGGTATAGAAAAA

Product: putative transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MHRVELRRFRPVLTEFPGVNLLIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETLRVGTLYGAQIYMSSGQGLSG
FDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLIAAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIE
QLSGNLTVVADSAFVETLTRLQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKV
PVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAKLPRYRPLFEEYAGDLDWRKL
AAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRLDPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIG
LGHLEDARRLAEAQGLNPSAWRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPD
EIQVEETAASSGAEPPTAAPRE

Sequences:

>Translated_502_residues
MHRVELRRFRPVLTEFPGVNLLIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETLRVGTLYGAQIYMSSGQGLSG
FDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLIAAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIE
QLSGNLTVVADSAFVETLTRLQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKV
PVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAKLPRYRPLFEEYAGDLDWRKL
AAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRLDPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIG
LGHLEDARRLAEAQGLNPSAWRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPD
EIQVEETAASSGAEPPTAAPRE
>Mature_502_residues
MHRVELRRFRPVLTEFPGVNLLIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETLRVGTLYGAQIYMSSGQGLSG
FDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLIAAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIE
QLSGNLTVVADSAFVETLTRLQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKV
PVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAKLPRYRPLFEEYAGDLDWRKL
AAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRLDPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIG
LGHLEDARRLAEAQGLNPSAWRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPD
EIQVEETAASSGAEPPTAAPRE

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=445, Percent_Identity=44.4943820224719, Blast_Score=378, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 56959; Mature: 56959

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRVELRRFRPVLTEFPGVNLLIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETL
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHE
RVGTLYGAQIYMSSGQGLSGFDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLI
EEEEEECEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCCEEEE
AAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIEQLSGNLTVVADSAFVETLTR
EECCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCHHHHHHHCCCEEEEECHHHHHHHHH
LQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKV
HHHHHCCCCHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCEEECCC
PVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAK
CEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LPRYRPLFEEYAGDLDWRKLAAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRL
CCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHCCCCCCC
DPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIGLGHLEDARRLAEAQGLNPSA
CHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCHHHHHHHHHHCCCCHHH
WRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCC
EIQVEETAASSGAEPPTAAPRE
CCCHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHRVELRRFRPVLTEFPGVNLLIRLRRVLFLLTSVLVLTACQPPGLVVDAPQPKAEAETL
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHE
RVGTLYGAQIYMSSGQGLSGFDYELAQKFADYLGKPLEMQPYSNRSELYDALAKGEIDLI
EEEEEECEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHCCCEEEE
AAGITESPNRRNRFRMGPPLYRVDQVVVYRQGNRAPESIEQLSGNLTVVADSAFVETLTR
EECCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCHHHHHHHCCCEEEEECHHHHHHHHH
LQQTHTNLSWEQTSEKDNDELIAMIASGELNYTLAQSTSLDINRRYMPELRSGLVLEEKV
HHHHHCCCCHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCEEECCC
PVVWLLPAQNSDALMSKLLAFWHQEKRAGTLAHLNEKYFGHVKRFDYVDTRAFIRAIDAK
CEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LPRYRPLFEEYAGDLDWRKLAAASYQESHWNPNARSPTGVRGMMMLTNATASQLGVTNRL
CCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHCCCCCCC
DPRQSIRGGADYLRDLINRLPESIPENQRMWFALAAYNIGLGHLEDARRLAEAQGLNPSA
CHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCHHHHHHHHHHCCCCHHH
WRDVKQVLPLLQKRKFYSQTRYGYARGGEAVHYVDSIRRYYDTLVWVDNQKPKDEPQLPD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCC
EIQVEETAASSGAEPPTAAPRE
CCCHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA