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The map label for this gene is lpxD [H]

Identifier: 119775386

GI number: 119775386

Start: 2714532

End: 2715392

Strand: Reverse

Name: lpxD [H]

Synonym: Sama_2251

Alternate gene names: 119775386

Gene position: 2715392-2714532 (Counterclockwise)

Preceding gene: 119775387

Following gene: 119775385

Centisome position: 63.06

GC content: 37.17

Gene sequence:

>861_bases
ATGGGCTTTCAACTTAATCGTGGTATATATGCTCAAGATCTTTTCGAATTACTAAAAGTTAAATTTGACTTTCCTATTAA
CAGTTTGATTACAAATATATCACCGTATGTCAGTGCGAATCAGAATAGCCTAACGTTTCTTACGGCAGAAACTGATTATA
AGAAGATGTGCGGTATTTGTTTTTCAAAAGAGAATGATCCAGATAATGGCTTTGTTTTAGTCGATAATCCGAGAGATCTA
TTTGCTCAAGCTTTGCTTGTTTTAAAATCTGAGAATCTAATTTCGGATGTTCATCCCCACTTTATCAGTCCCAAAGCTAT
AATTTCTCCAACCGCCTCAATTGACTTCGGTGTACAGATCGCTGACGATGTCGTAATCGAAGACTTTGTTTCTGTAAAGT
CTGGAACCATCATAGGTGAAGGGACCTTGATTAGATCCTTTACTTGCGTAGGTAGTGAAGGATTTGGTATTGCGAAATCA
GCTGATGGAAATAATATAAGATTTCTTCACCTAGGAGGCGTTAAAATAGGTAAGTATTGCGAGATTGGGCTTTTTAATTC
TATTAACTGTGGTACTTTGTCGGATACAATCATTGGCGATTATGTGAAGACTGACGCACATGTACACATCGCTCATAATT
GTACAATAGGTAACAACTCAATATTAACAGCCGCAGCCGTGCTAAGTGGTGGTGTTTCTATAGGTGATAATGTTTGGCTT
GGACCAAACTCTTCCATAATTCAAAAAACCAGTATAGGAAGTGATAGCTTAATAGGAATAGGTGCTGTAGTGACTAAAAA
CATAGACTCCAATGTAATCGCGGCAGGGAATCCATCAAAGATTTTAAGGAGTAATAAATGA

Upstream 100 bases:

>100_bases
TTCTCAAGAGTTTTTGCAGTCGTTGGCTATAATACGCGGCGCTATTGTAGGAGTCGATTTGGCTGAAAAGTTTGAAGTTA
TAAGAATGGTGGTAAAGTAA

Downstream 100 bases:

>100_bases
ATACTAAAGCAGTCGTAGTTACAGGTGCCACAGGAGGAATTGGTTGGACTATTGCCGAATACCTAATGTCTCTTGAATAT
TTCGTTATCGGCACTACCCA

Product: UDP-3-O-(3-hydroxymyristoyl)-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGFQLNRGIYAQDLFELLKVKFDFPINSLITNISPYVSANQNSLTFLTAETDYKKMCGICFSKENDPDNGFVLVDNPRDL
FAQALLVLKSENLISDVHPHFISPKAIISPTASIDFGVQIADDVVIEDFVSVKSGTIIGEGTLIRSFTCVGSEGFGIAKS
ADGNNIRFLHLGGVKIGKYCEIGLFNSINCGTLSDTIIGDYVKTDAHVHIAHNCTIGNNSILTAAAVLSGGVSIGDNVWL
GPNSSIIQKTSIGSDSLIGIGAVVTKNIDSNVIAAGNPSKILRSNK

Sequences:

>Translated_286_residues
MGFQLNRGIYAQDLFELLKVKFDFPINSLITNISPYVSANQNSLTFLTAETDYKKMCGICFSKENDPDNGFVLVDNPRDL
FAQALLVLKSENLISDVHPHFISPKAIISPTASIDFGVQIADDVVIEDFVSVKSGTIIGEGTLIRSFTCVGSEGFGIAKS
ADGNNIRFLHLGGVKIGKYCEIGLFNSINCGTLSDTIIGDYVKTDAHVHIAHNCTIGNNSILTAAAVLSGGVSIGDNVWL
GPNSSIIQKTSIGSDSLIGIGAVVTKNIDSNVIAAGNPSKILRSNK
>Mature_285_residues
GFQLNRGIYAQDLFELLKVKFDFPINSLITNISPYVSANQNSLTFLTAETDYKKMCGICFSKENDPDNGFVLVDNPRDLF
AQALLVLKSENLISDVHPHFISPKAIISPTASIDFGVQIADDVVIEDFVSVKSGTIIGEGTLIRSFTCVGSEGFGIAKSA
DGNNIRFLHLGGVKIGKYCEIGLFNSINCGTLSDTIIGDYVKTDAHVHIAHNCTIGNNSILTAAAVLSGGVSIGDNVWLG
PNSSIIQKTSIGSDSLIGIGAVVTKNIDSNVIAAGNPSKILRSNK

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=317, Percent_Identity=27.1293375394322, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 30443; Mature: 30312

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFQLNRGIYAQDLFELLKVKFDFPINSLITNISPYVSANQNSLTFLTAETDYKKMCGIC
CCEECCCCCCHHHHHHHHHEEECCCHHHHHHCCCCCEECCCCEEEEEEECCCHHHHHCEE
FSKENDPDNGFVLVDNPRDLFAQALLVLKSENLISDVHPHFISPKAIISPTASIDFGVQI
ECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEECCCCCCEECEEE
ADDVVIEDFVSVKSGTIIGEGTLIRSFTCVGSEGFGIAKSADGNNIRFLHLGGVKIGKYC
HHHHHHHHHHHHCCCEEEECCEEEEEEEEECCCCCCEEECCCCCCEEEEEECCEEECCEE
EIGLFNSINCGTLSDTIIGDYVKTDAHVHIAHNCTIGNNSILTAAAVLSGGVSIGDNVWL
EECCCCCCCCCCCCHHHHHHHEECCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEE
GPNSSIIQKTSIGSDSLIGIGAVVTKNIDSNVIAAGNPSKILRSNK
CCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEECCCCHHHHCCCC
>Mature Secondary Structure 
GFQLNRGIYAQDLFELLKVKFDFPINSLITNISPYVSANQNSLTFLTAETDYKKMCGIC
CEECCCCCCHHHHHHHHHEEECCCHHHHHHCCCCCEECCCCEEEEEEECCCHHHHHCEE
FSKENDPDNGFVLVDNPRDLFAQALLVLKSENLISDVHPHFISPKAIISPTASIDFGVQI
ECCCCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEECCCCCCEECEEE
ADDVVIEDFVSVKSGTIIGEGTLIRSFTCVGSEGFGIAKSADGNNIRFLHLGGVKIGKYC
HHHHHHHHHHHHCCCEEEECCEEEEEEEEECCCCCCEEECCCCCCEEEEEECCEEECCEE
EIGLFNSINCGTLSDTIIGDYVKTDAHVHIAHNCTIGNNSILTAAAVLSGGVSIGDNVWL
EECCCCCCCCCCCCHHHHHHHEECCCEEEEEEEEEECCCCHHHHHHHHHCCCCCCCEEEE
GPNSSIIQKTSIGSDSLIGIGAVVTKNIDSNVIAAGNPSKILRSNK
CCCCCEEEEECCCCCCEEEEEEEEEECCCCCEEECCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]