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The map label for this gene is ycbL [H]

Identifier: 119775277

GI number: 119775277

Start: 2587229

End: 2587873

Strand: Reverse

Name: ycbL [H]

Synonym: Sama_2142

Alternate gene names: 119775277

Gene position: 2587873-2587229 (Counterclockwise)

Preceding gene: 119775280

Following gene: 119775276

Centisome position: 60.1

GC content: 56.43

Gene sequence:

>645_bases
ATGAAATACCAGATAATTCCCGTGACGCCTTTTCAGCAAAACTGCACTCTCATTTGGTGTGAAAACACCCGCAAGGCTGC
GGTGGTGGACCCGGGTGGAAACCTCGAGCGTATTTACGAGGCGCTGGAAAAACATGGACTGACATTGGATAAAATTCTGC
TGACCCATGGCCACATAGATCATGTGGGCGGCGCCGCCAAGCTCTCAACGGAAACCGGCGTTGCCATTGAAGGCCCCCAC
GTGGATGACGCCTTCTGGTTGGAAAACCTGCCCCGTCAGAGCCAAAACTTTGGGTTTGCCCATTGCGACGCCTTTGCCCC
TTCCCGCTACCTGGAGGAAGGCGAGAGTCTGCGTATTGGCGATGTATCGCTTGCTGTGATGCATTGCCCCGGGCATACGC
CCGGACACCTGGTGTTTTTCGAGCCTGTCACCAAGTTGGCCCTGGTGGGGGATGTGCTCTTTCGTGGCTCAATTGGCCGA
ACCGACTTCCCCGGCTCAGACCACAAAGCACTCATCAACTCCATCACTACCAAGCTCTGGCCTCTGGGTAAAGAGGTTGC
TTTTATCCCCGGGCACGGCCCCATGTCTACCTTTGCCGAAGAGCGGGCTCACAACCCCTTCGTGGCCGACCAGCTGCTGG
GTTAA

Upstream 100 bases:

>100_bases
TGCCAAAGCCCTATCAAGATCAATTTCTGCCCGGGAAAACTGGCACACAATGGCTAGAATCACTTAATCTAGCGCCCAAA
ATACAAAAGAGAATGCGACT

Downstream 100 bases:

>100_bases
CACCTGTTTCTGCTTATCCTGGCTCCGTGAGATTCTGTCATCGGAGCCATTCTATTCTTTGTCGCTGCTTCTTCCATCAG
TCTGTTCATTGCCTGCCGGC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKYQIIPVTPFQQNCTLIWCENTRKAAVVDPGGNLERIYEALEKHGLTLDKILLTHGHIDHVGGAAKLSTETGVAIEGPH
VDDAFWLENLPRQSQNFGFAHCDAFAPSRYLEEGESLRIGDVSLAVMHCPGHTPGHLVFFEPVTKLALVGDVLFRGSIGR
TDFPGSDHKALINSITTKLWPLGKEVAFIPGHGPMSTFAEERAHNPFVADQLLG

Sequences:

>Translated_214_residues
MKYQIIPVTPFQQNCTLIWCENTRKAAVVDPGGNLERIYEALEKHGLTLDKILLTHGHIDHVGGAAKLSTETGVAIEGPH
VDDAFWLENLPRQSQNFGFAHCDAFAPSRYLEEGESLRIGDVSLAVMHCPGHTPGHLVFFEPVTKLALVGDVLFRGSIGR
TDFPGSDHKALINSITTKLWPLGKEVAFIPGHGPMSTFAEERAHNPFVADQLLG
>Mature_214_residues
MKYQIIPVTPFQQNCTLIWCENTRKAAVVDPGGNLERIYEALEKHGLTLDKILLTHGHIDHVGGAAKLSTETGVAIEGPH
VDDAFWLENLPRQSQNFGFAHCDAFAPSRYLEEGESLRIGDVSLAVMHCPGHTPGHLVFFEPVTKLALVGDVLFRGSIGR
TDFPGSDHKALINSITTKLWPLGKEVAFIPGHGPMSTFAEERAHNPFVADQLLG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=201, Percent_Identity=27.8606965174129, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787158, Length=212, Percent_Identity=57.5471698113208, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23428; Mature: 23428

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQIIPVTPFQQNCTLIWCENTRKAAVVDPGGNLERIYEALEKHGLTLDKILLTHGHID
CCEEEEECCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHH
HVGGAAKLSTETGVAIEGPHVDDAFWLENLPRQSQNFGFAHCDAFAPSRYLEEGESLRIG
HCCCCEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCEEECCCCCCHHHHHCCCCEEEC
DVSLAVMHCPGHTPGHLVFFEPVTKLALVGDVLFRGSIGRTDFPGSDHKALINSITTKLW
CEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PLGKEVAFIPGHGPMSTFAEERAHNPFVADQLLG
CCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHCC
>Mature Secondary Structure
MKYQIIPVTPFQQNCTLIWCENTRKAAVVDPGGNLERIYEALEKHGLTLDKILLTHGHID
CCEEEEECCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCHH
HVGGAAKLSTETGVAIEGPHVDDAFWLENLPRQSQNFGFAHCDAFAPSRYLEEGESLRIG
HCCCCEEECCCCCEEEECCCCCHHHHHHHCCCCCCCCCEEECCCCCCHHHHHCCCCEEEC
DVSLAVMHCPGHTPGHLVFFEPVTKLALVGDVLFRGSIGRTDFPGSDHKALINSITTKLW
CEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
PLGKEVAFIPGHGPMSTFAEERAHNPFVADQLLG
CCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]