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The map label for this gene is yafE [C]

Identifier: 119775169

GI number: 119775169

Start: 2471973

End: 2472581

Strand: Reverse

Name: yafE [C]

Synonym: Sama_2034

Alternate gene names: 119775169

Gene position: 2472581-2471973 (Counterclockwise)

Preceding gene: 119775173

Following gene: 119775167

Centisome position: 57.42

GC content: 51.72

Gene sequence:

>609_bases
ATGAAACTGAATCAAAATGAAAAGGCAGTTGTTACTTCCAAAGGCAGGGCTTGGATCCAATCCACATTGGAAGCCAGGCT
ACTACAAAGCCTCTTTCCCAAAGACCTGCCAGTGTTGGAACGGGCACTGGAAATTGGCTGTGGCAGTGGAAACGGCATGG
AATTTCTGAAACATCGCCTCAATGCCCGGCAAGTCATCGCCATGGATTTGGACGAAGAGATGTTGGCCCTCAGTGCAAAG
CGTTGGCAGGGAAACGATTGGGCCTTTTTCACCGAGGCGAATGCCTGTCAGATGCCCTTTGATGAAACGGCGTTTGATTT
GGTTGTTGAGTTTGCGGTGTTCCATCATGTGCCGGATTGGCAGGGGGCCCTGGCTGAGGTGGCCAGGGTGCTTAAACCCG
GCGGCTACTTTTTGTATTGGGATCTGTACCGGTTTGCCATCTGTAACCCAATCAGTCGCAGGTTATTTGAACATCCGATG
GAAAACCGGTTTTCTCACCGTGAGTTTACAGCAGAGCTTGAGCGTCTGGGATTGGAATGTCGCCAGAGTCGCGAGCTTCC
GGCAATGGCCGGTATGGGCTTGTTTCAAAAAGCGGCGGCCATCACTTAG

Upstream 100 bases:

>100_bases
CGACAAGGGGATCACTTGAGCGTAGCGACAAACCCGGTTTGCAGTGTCACCGGCGCTGCCAGTGAGGGCATTTATCAAAA
TCACATGACGAAGAGATGCT

Downstream 100 bases:

>100_bases
CCGAACCGTCAAGCCACACAAGGGTGTCAGGGTTGACGCCAAGAGCCCGGATTTTATCGGTAAAGTAAACCCGTTCTTCG
TCTGTGAGAGAGGGTTCCCT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MKLNQNEKAVVTSKGRAWIQSTLEARLLQSLFPKDLPVLERALEIGCGSGNGMEFLKHRLNARQVIAMDLDEEMLALSAK
RWQGNDWAFFTEANACQMPFDETAFDLVVEFAVFHHVPDWQGALAEVARVLKPGGYFLYWDLYRFAICNPISRRLFEHPM
ENRFSHREFTAELERLGLECRQSRELPAMAGMGLFQKAAAIT

Sequences:

>Translated_202_residues
MKLNQNEKAVVTSKGRAWIQSTLEARLLQSLFPKDLPVLERALEIGCGSGNGMEFLKHRLNARQVIAMDLDEEMLALSAK
RWQGNDWAFFTEANACQMPFDETAFDLVVEFAVFHHVPDWQGALAEVARVLKPGGYFLYWDLYRFAICNPISRRLFEHPM
ENRFSHREFTAELERLGLECRQSRELPAMAGMGLFQKAAAIT
>Mature_202_residues
MKLNQNEKAVVTSKGRAWIQSTLEARLLQSLFPKDLPVLERALEIGCGSGNGMEFLKHRLNARQVIAMDLDEEMLALSAK
RWQGNDWAFFTEANACQMPFDETAFDLVVEFAVFHHVPDWQGALAEVARVLKPGGYFLYWDLYRFAICNPISRRLFEHPM
ENRFSHREFTAELERLGLECRQSRELPAMAGMGLFQKAAAIT

Specific function: Catalyzes the methylation of the lipid moiety of the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycoserosates to form phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 23112; Mature: 23112

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNQNEKAVVTSKGRAWIQSTLEARLLQSLFPKDLPVLERALEIGCGSGNGMEFLKHRL
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
NARQVIAMDLDEEMLALSAKRWQGNDWAFFTEANACQMPFDETAFDLVVEFAVFHHVPDW
CCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
QGALAEVARVLKPGGYFLYWDLYRFAICNPISRRLFEHPMENRFSHREFTAELERLGLEC
HHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RQSRELPAMAGMGLFQKAAAIT
HHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLNQNEKAVVTSKGRAWIQSTLEARLLQSLFPKDLPVLERALEIGCGSGNGMEFLKHRL
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
NARQVIAMDLDEEMLALSAKRWQGNDWAFFTEANACQMPFDETAFDLVVEFAVFHHVPDW
CCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCC
QGALAEVARVLKPGGYFLYWDLYRFAICNPISRRLFEHPMENRFSHREFTAELERLGLEC
HHHHHHHHHHHCCCCEEEHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RQSRELPAMAGMGLFQKAAAIT
HHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]