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The map label for this gene is ychM [C]

Identifier: 119775149

GI number: 119775149

Start: 2447718

End: 2449496

Strand: Reverse

Name: ychM [C]

Synonym: Sama_2014

Alternate gene names: 119775149

Gene position: 2449496-2447718 (Counterclockwise)

Preceding gene: 119775150

Following gene: 119775145

Centisome position: 56.88

GC content: 54.86

Gene sequence:

>1779_bases
ATGGATGAATCGAAAGGAGTCTGTGTGTCTCGTTTGTTGTCCCTGATGCCGGGTCTGGCATCATTTAAAGACTACCGCAA
AGAATGGTTCAAAGATGATGTGCGTGCGGCATTCTCTGTGAGTGCCGTGGCGCTGCCGGTGGCCATTGCCTATGCGCAGC
TTACTGGGGTGAACGCCCTGGTGGGCCTGTATTCCTGTGTGCTGCCCATGATGGTTTACGCCCTGTTTGGTACCTCCCGT
CAGTTAATCGTGGGGCCCGATGCAGCCACCTGTGCCGTGGTGGCCGCTGTGGTGACACCGCTGGCAGCGGGCGACAGTAT
CAAACACTGGCAGCTGGCCATGACCATGACCGCCATGACGGGATTCTGGTGTCTTATCGCCAGTCGTTTCAAATTGGGGG
TACTGGCCGATTTTCTGTCAAAACCCATCTTAATGGGGCTGTTAAACGGTGTGGCCATCACCATTATTGTGGGTCAGGCC
TCAAAGATCCTCGGCTTCAGCTTTGACGAGCGCTATTTGCTTGACCGTATCGCTGCCGCGCCCGGATATCTGTCGCAAAT
TCACTGGGCCACCCTGGCGATGAGCCTGGGAGCCGTGCTGATCTTCCTTTTGGTTAAACGTTTCAGGCCCACTTGGCCAG
CCGCCATGTTGGTGATTGTGGTGTCTACTCTGGTGGCATGGGCGGCAAATCTGGAGCAGTTTGATGTGGCGCTGGTGGGG
GATGTAAGCATCAATATGCCGGCATTTCAGATGCCAGCCTTTGATATTGGTATTGCCCGGGAATTGGTCATGCCAGCCCT
TAACCTCGCCATGGTCAGCTTTGTAAGCATGATGCTCACGGCGAGAAGTTTTGCTGCAAAAAATGGCTATGATATTGACC
CTGATAAAGAATTCAGGGCCTTGGGTATTGCCAACATCGCCTCCGCATTGTCTCAGGGTTTTGCGGTGAGCGGCGCTGAT
TCCCGTACGGCGGTGAATGACGCCAGTGGTGGCAAGACGCAATTGGTGTCGCTGATTGCCGCGCTTATCATAGGCATAAT
TGCCTGGCTCTTTACCGCGCCTCTGGCCTTTATTCCCTCGGCGGCGCTGGGGGTTGTGCTGGTGGTGGCATCCTGGTCGT
TGCTGGATCTTAAAACCCTGTGGAAGCTCAGAAAGCGCGATCAAAGGGCGTTTTTACTGGCCATGACCACCTTTGTGGCC
GTGTTGCTGATTGGCGTTATTCCCGGTATTACTCTGGCGGTACTCTTGGGGCTGTTTCAGTTTTTGCAGGTGGTTATGCG
CCCGAGCGACCAGTGCCTTGGACTCGATGCCAAGGGCACGCTGCGAAGCCTCGACGGCAGCGACAAAGCCGTGGCCGTGC
CCGGGGTATTTATCTACCGTTTTAACTCGCCGTTGACCTACTTTAATGCCAGCTATTTCAAACGACGTCTTTTGGAGCGT
ATCGCCGCAGAGCCGGAAACTCCTGAATGCGTGATTATTGATGCGGTGCCGTGCTTTACTCACCCGGATATCAGTGTGAT
GGCCATGCTGTCTGACTTATATGCATTGCTGAAACGCAGACATATCCGGCTGATTTTGGCTGGCCGCAAGCGGCAGTTGT
TGTCCTGGTGTGAGGCGCAGGGCATACCGACGGGGGAAGGAGGGTTGCTTATCCGCTCTGACCTCTATCTTGCACTCAAG
ATGAATCAGGCATATAAGCAGGCTCTGGCGGATGGCCAGGCGCCGGTACTCAAGCGACCTGTGGATTTGGACCTGGTGCT
GGAACACAGCCATCTGTAA

Upstream 100 bases:

>100_bases
GCCTTGCTGCTGACGTTGCCAATGATACTGATGTAGTCAATGGATTTATTTTTACTGGCAGGGATAGACAAACTAAGCTA
ATTCAACGATAAGGCAGGGA

Downstream 100 bases:

>100_bases
CAAAAAAGCCCCGGAACCCGGGGCTTTTTTGTACAACAGGATTAATCTCTGCCAAGCATATCGCAGGGGATAAGCCCTTG
ATAAAAATAATAACCGGCAG

Product: sulfate permease family protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MDESKGVCVSRLLSLMPGLASFKDYRKEWFKDDVRAAFSVSAVALPVAIAYAQLTGVNALVGLYSCVLPMMVYALFGTSR
QLIVGPDAATCAVVAAVVTPLAAGDSIKHWQLAMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQA
SKILGFSFDERYLLDRIAAAPGYLSQIHWATLAMSLGAVLIFLLVKRFRPTWPAAMLVIVVSTLVAWAANLEQFDVALVG
DVSINMPAFQMPAFDIGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDPDKEFRALGIANIASALSQGFAVSGAD
SRTAVNDASGGKTQLVSLIAALIIGIIAWLFTAPLAFIPSAALGVVLVVASWSLLDLKTLWKLRKRDQRAFLLAMTTFVA
VLLIGVIPGITLAVLLGLFQFLQVVMRPSDQCLGLDAKGTLRSLDGSDKAVAVPGVFIYRFNSPLTYFNASYFKRRLLER
IAAEPETPECVIIDAVPCFTHPDISVMAMLSDLYALLKRRHIRLILAGRKRQLLSWCEAQGIPTGEGGLLIRSDLYLALK
MNQAYKQALADGQAPVLKRPVDLDLVLEHSHL

Sequences:

>Translated_592_residues
MDESKGVCVSRLLSLMPGLASFKDYRKEWFKDDVRAAFSVSAVALPVAIAYAQLTGVNALVGLYSCVLPMMVYALFGTSR
QLIVGPDAATCAVVAAVVTPLAAGDSIKHWQLAMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQA
SKILGFSFDERYLLDRIAAAPGYLSQIHWATLAMSLGAVLIFLLVKRFRPTWPAAMLVIVVSTLVAWAANLEQFDVALVG
DVSINMPAFQMPAFDIGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDPDKEFRALGIANIASALSQGFAVSGAD
SRTAVNDASGGKTQLVSLIAALIIGIIAWLFTAPLAFIPSAALGVVLVVASWSLLDLKTLWKLRKRDQRAFLLAMTTFVA
VLLIGVIPGITLAVLLGLFQFLQVVMRPSDQCLGLDAKGTLRSLDGSDKAVAVPGVFIYRFNSPLTYFNASYFKRRLLER
IAAEPETPECVIIDAVPCFTHPDISVMAMLSDLYALLKRRHIRLILAGRKRQLLSWCEAQGIPTGEGGLLIRSDLYLALK
MNQAYKQALADGQAPVLKRPVDLDLVLEHSHL
>Mature_592_residues
MDESKGVCVSRLLSLMPGLASFKDYRKEWFKDDVRAAFSVSAVALPVAIAYAQLTGVNALVGLYSCVLPMMVYALFGTSR
QLIVGPDAATCAVVAAVVTPLAAGDSIKHWQLAMTMTAMTGFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQA
SKILGFSFDERYLLDRIAAAPGYLSQIHWATLAMSLGAVLIFLLVKRFRPTWPAAMLVIVVSTLVAWAANLEQFDVALVG
DVSINMPAFQMPAFDIGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDPDKEFRALGIANIASALSQGFAVSGAD
SRTAVNDASGGKTQLVSLIAALIIGIIAWLFTAPLAFIPSAALGVVLVVASWSLLDLKTLWKLRKRDQRAFLLAMTTFVA
VLLIGVIPGITLAVLLGLFQFLQVVMRPSDQCLGLDAKGTLRSLDGSDKAVAVPGVFIYRFNSPLTYFNASYFKRRLLER
IAAEPETPECVIIDAVPCFTHPDISVMAMLSDLYALLKRRHIRLILAGRKRQLLSWCEAQGIPTGEGGLLIRSDLYLALK
MNQAYKQALADGQAPVLKRPVDLDLVLEHSHL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=500, Percent_Identity=25.6, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI39752683, Length=500, Percent_Identity=25.6, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557535, Length=521, Percent_Identity=26.8714011516315, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI94721259, Length=516, Percent_Identity=26.1627906976744, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721257, Length=516, Percent_Identity=26.1627906976744, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721253, Length=516, Percent_Identity=26.1627906976744, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI269784651, Length=494, Percent_Identity=24.4939271255061, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI94721255, Length=516, Percent_Identity=26.1627906976744, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI4505697, Length=511, Percent_Identity=27.2015655577299, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI262206105, Length=553, Percent_Identity=25.1356238698011, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI262206075, Length=553, Percent_Identity=25.1356238698011, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI262206069, Length=553, Percent_Identity=25.1356238698011, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI262206063, Length=553, Percent_Identity=25.1356238698011, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI45827802, Length=441, Percent_Identity=26.3038548752834, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI47131207, Length=527, Percent_Identity=24.8576850094877, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI20336272, Length=527, Percent_Identity=24.8576850094877, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI217272867, Length=527, Percent_Identity=22.5806451612903, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI16418413, Length=520, Percent_Identity=22.1153846153846, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI100913030, Length=520, Percent_Identity=22.8846153846154, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI16306483, Length=576, Percent_Identity=21.3541666666667, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI20336282, Length=576, Percent_Identity=21.3541666666667, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI16418457, Length=520, Percent_Identity=22.6923076923077, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI301601599, Length=520, Percent_Identity=22.6923076923077, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI301601602, Length=233, Percent_Identity=24.8927038626609, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI65506789, Length=409, Percent_Identity=26.6503667481663, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI45827804, Length=252, Percent_Identity=23.4126984126984, Blast_Score=67, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI86565215, Length=500, Percent_Identity=26.4, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551690, Length=535, Percent_Identity=24.2990654205607, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI86564196, Length=522, Percent_Identity=25.8620689655172, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17566848, Length=513, Percent_Identity=23.5867446393762, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193203292, Length=518, Percent_Identity=24.3243243243243, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17562578, Length=515, Percent_Identity=24.8543689320388, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI86564876, Length=386, Percent_Identity=23.0569948186528, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86565209, Length=233, Percent_Identity=29.1845493562232, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86565211, Length=233, Percent_Identity=29.1845493562232, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI86565213, Length=250, Percent_Identity=26, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=569, Percent_Identity=23.5500878734622, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323121, Length=476, Percent_Identity=23.5294117647059, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319771, Length=453, Percent_Identity=23.3995584988962, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666186, Length=527, Percent_Identity=22.7703984819734, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651449, Length=631, Percent_Identity=23.7717908082409, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24649801, Length=488, Percent_Identity=24.7950819672131, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI85815873, Length=593, Percent_Identity=24.4519392917369, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21358229, Length=465, Percent_Identity=26.0215053763441, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI19922482, Length=521, Percent_Identity=24.9520153550864, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24663084, Length=441, Percent_Identity=24.7165532879819, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357695, Length=441, Percent_Identity=24.7165532879819, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21358633, Length=436, Percent_Identity=24.3119266055046, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355087, Length=435, Percent_Identity=25.2873563218391, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24647160, Length=435, Percent_Identity=25.2873563218391, Blast_Score=108, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 64048; Mature: 64048

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESKGVCVSRLLSLMPGLASFKDYRKEWFKDDVRAAFSVSAVALPVAIAYAQLTGVNAL
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLYSCVLPMMVYALFGTSRQLIVGPDAATCAVVAAVVTPLAAGDSIKHWQLAMTMTAMT
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQASKILGFSFDERYLLDRIAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCC
PGYLSQIHWATLAMSLGAVLIFLLVKRFRPTWPAAMLVIVVSTLVAWAANLEQFDVALVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHCCEEEEE
DVSINMPAFQMPAFDIGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDPDKEFRA
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGIANIASALSQGFAVSGADSRTAVNDASGGKTQLVSLIAALIIGIIAWLFTAPLAFIPS
HHHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AALGVVLVVASWSLLDLKTLWKLRKRDQRAFLLAMTTFVAVLLIGVIPGITLAVLLGLFQ
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQVVMRPSDQCLGLDAKGTLRSLDGSDKAVAVPGVFIYRFNSPLTYFNASYFKRRLLER
HHHHHHCCCCHHCCCCCCCCHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHH
IAAEPETPECVIIDAVPCFTHPDISVMAMLSDLYALLKRRHIRLILAGRKRQLLSWCEAQ
HHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHC
GIPTGEGGLLIRSDLYLALKMNQAYKQALADGQAPVLKRPVDLDLVLEHSHL
CCCCCCCCEEEECCEEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MDESKGVCVSRLLSLMPGLASFKDYRKEWFKDDVRAAFSVSAVALPVAIAYAQLTGVNAL
CCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLYSCVLPMMVYALFGTSRQLIVGPDAATCAVVAAVVTPLAAGDSIKHWQLAMTMTAMT
HHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GFWCLIASRFKLGVLADFLSKPILMGLLNGVAITIIVGQASKILGFSFDERYLLDRIAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCHHHHHHHHHCC
PGYLSQIHWATLAMSLGAVLIFLLVKRFRPTWPAAMLVIVVSTLVAWAANLEQFDVALVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCHHHCCEEEEE
DVSINMPAFQMPAFDIGIARELVMPALNLAMVSFVSMMLTARSFAAKNGYDIDPDKEFRA
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LGIANIASALSQGFAVSGADSRTAVNDASGGKTQLVSLIAALIIGIIAWLFTAPLAFIPS
HHHHHHHHHHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AALGVVLVVASWSLLDLKTLWKLRKRDQRAFLLAMTTFVAVLLIGVIPGITLAVLLGLFQ
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQVVMRPSDQCLGLDAKGTLRSLDGSDKAVAVPGVFIYRFNSPLTYFNASYFKRRLLER
HHHHHHCCCCHHCCCCCCCCHHCCCCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHH
IAAEPETPECVIIDAVPCFTHPDISVMAMLSDLYALLKRRHIRLILAGRKRQLLSWCEAQ
HHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHC
GIPTGEGGLLIRSDLYLALKMNQAYKQALADGQAPVLKRPVDLDLVLEHSHL
CCCCCCCCEEEECCEEEEEEHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]