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The map label for this gene is yfbK [C]

Identifier: 119775138

GI number: 119775138

Start: 2432403

End: 2434664

Strand: Reverse

Name: yfbK [C]

Synonym: Sama_2003

Alternate gene names: 119775138

Gene position: 2434664-2432403 (Counterclockwise)

Preceding gene: 119775139

Following gene: 119775137

Centisome position: 56.54

GC content: 57.82

Gene sequence:

>2262_bases
ATGAAGGATGATAAGAGTATGTATAGCCAAAGGAAGGTCGTGCCCAAGGTGGAGATGAAGCAAGGCCTGACTGCACTGGC
AATGATGGCGTTGCTGGCAGCGCCAACAGTCAGCGCGAGCTCAGCCAGCACAGTGCAGCCCGTAACCTTGCCACTCGATG
GTCCAATGGCTGGCCAGGGCAGTACTTCGCCAGGCGACATCATAGCACCGGGCCATGGCGGGGAGCTGATGTTTGAAGAC
GAGGGCACGGAGCAAGTCAGTCTTGCCCTCGATACCCGCTACACGGTTAAGGTCAGTGCCTTGGTCAGCCGGGTTACAGT
TTCTCAAACCTTTCAAAATCAGAGTAATAGAGTGATAAACGGCCACTACCGCTTTGCGCTGGCGCCCAATGCGGCGGTGA
GTGGCATGCGCCTTACAATCGGCGAACGCCTGATTGAAGGAGAGATCCAGGAAAAAGCTCACGCAGAGCGGGTATACGAG
CAAGCAAAACGGGATGGTAAACGGGCGAGCCTGGTCAGCCACAGCGAAAGCAATCTTTTTTCGACACGGATTGCCAATTT
CATGCCCGGCGAAACCCTTACCGTCAGTATCGATTATCAGGAGATTCTGCACCCACAAGCGGGCCGGGTTGAGCTCAGGA
TCCCCACTGCACAAACGCCAAGGTATGGCGCCTCAGCAATGCTGCCTTCGGCGCAGAACAGGATGCAGGATGAGCCTTGG
GTATCCGGGGTGCAGGGCGCGGCGCAGAACCATCTTCATGCCGCTGCGCCTTTTTGGCCCGCCACCCGGGCAGAGGCTCC
GGCAGACACGCCAACACCCTCGCTGTCACTCAGCGCCAGTATTTTTGGCTTTGCCGTGGCGGCGGTCGAAAGCCCATCCC
ATGGCTTGTGTGAGCAAGGCTATCGCGATGGTGGCTGGCAGTTATCGCTTTGCCCCGACACCGAGGCTGACAGGGATTTG
GTGCTGTCCTGGGTGATTAACGAAGGCAGTGAGCCGGTTGCAGACTTTTTGGTGCAGCCGGGCTACAGCTATCCCGCCGC
TGTGGAAAGCGCAAACACTCAGTATGGAACTGCTCAGGATAAAGCCAAACAGGATGAATACGTCCGGGTAGATTTTTCCC
AGGGGAATTACAGCCACGGTTTGCTGACCTTTATGCCACCTCAACCCAATTTGGCCAATCGCCTGGCGCGGGAGCTGGTA
TTGGTGATCGATACCTCAGGTTCCATGGCCGGAGACTCCATGGTGCAGGCAAGAAGTGCCCTTATCCACGCGCTCGGCGG
TTTGGGGCCACAGGACAGCTTCAATATTATTGCTTTTTCCAGTGATGCCAGGCCGTTGTGGCCGGACGCAAAACCGGCAA
CGGCATTTAATCTCGGGGCAGCCCAGCAATTTGTGCGCAGCCTTGAGGCCGATGGCGGCACTGAGATGGCATCTGCGTTG
GAGCTGGCCCTTAAAACGCCTTCAGTTGTAGATGAAGACACCAAACGGTTGCGACAGGTGCTTTTTATTACCGATGGCGC
CGTTAATGGCGAAGATGCGCTGTTTAATCTGATTGAGCGGCGTCTGGGCACATCGCGGCTTTTCCCCGTGGCTATCGGCG
CCGCGCCAAACGGGTATTTCATGAGCCGGGCGGCTGCAGCAGGTCGTGGCAGCTTTACCTTTATCGGTCATGGCGGCGAA
GTGGCAGAAAAAATGAATCAGCTCTTGAGTCGCATTGAGCACCCCGTGGTTAGCGATCTGTCCGTGACCTGGGCTGACGG
TAGCCCCGTTGATGCCATGCCTGGGGTATTGCCCGACTTGTATGCGGGCGAGGCGCTTAACCTGAGCCTCAGAACGGTCC
CCGATGCGCTGATGCCCATCATAGTCAAAGGTAATACGGACGGCCAAATCTGGGAGCGCAAGCTTACCCCACGTGCCGTG
CCGGGCGGCAGCGGCCTTGACCTGCAATATGGCAAAGCCCGGGTTGATGACCTTGTCCGACAAACATTAACACCTTCCCA
GCGGCGTGCAGCCACTGTGGCGTTGGGACTGGAATATCACCTTGTCACAGCCCACACCAGCCTGGTTGCCGTGGATAAAA
CCCGGGTCTCACACGGCCAGGGACTGGATGCCAGGTTGCCGGAGGCAACGCCCCATGGCTGGCAAGGCGGCAGATTGCCC
CAAACCGCGTCGGGTAGCCTGGGATTGATGTTGGCCGGCGCTTTGCTGGTGCTGTTTGCTATCGCAGCGGCAACGTGGAG
GCGGGAAGATGAAGCGGCTTAG

Upstream 100 bases:

>100_bases
TCGTGTGACTCTGGAGCTGGTTCCTGCGGATACCAGCATGGCGGCAACGCACTGATAAAAGTCCATTCATAACAACGGCA
AAGTACGGGTAATGAATAGC

Downstream 100 bases:

>100_bases
ATTTGGGCCCCGACACCGCAGACGCTGGCCCTTGTTGCTGTTGTTATCGGGAGTTGTTCTTATCAGTTTTGGAGGATATA
TGCAGGCAAAAGCATTACTT

Product: inter-alpha-trypsin inhibitor domain-containing protein

Products: NA

Alternate protein names: Vault Protein Inter-Alpha-Trypsin; Inter-Alpha-Trypsin Inhibitor Domain-Containing Protein; Von Willebrand Factor Type A Domain-Containing Protein; Von Willebrand Factor Type A; Vault Protein Inter-Alpha-Trypsin Domain Protein; Cell Wall Anchor Domain-Containing Protein; Vault Protein Inter-Alpha-Trypsin Domain-Containing Protein; Von Willebrand Factor Type A Domain Protein; LPXTG-Motif Cell Wall Anchor Domain-Containing Protein; Transmembrane Protein; LPXTG-Motif Cell Wall Anchor Domain Protein; Vault Protein Inter-Alpha-Trypsin Domain; Inter-Alpha-Trypsin Inhibitor Domain Protein; Von Willebrand Factor

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MKDDKSMYSQRKVVPKVEMKQGLTALAMMALLAAPTVSASSASTVQPVTLPLDGPMAGQGSTSPGDIIAPGHGGELMFED
EGTEQVSLALDTRYTVKVSALVSRVTVSQTFQNQSNRVINGHYRFALAPNAAVSGMRLTIGERLIEGEIQEKAHAERVYE
QAKRDGKRASLVSHSESNLFSTRIANFMPGETLTVSIDYQEILHPQAGRVELRIPTAQTPRYGASAMLPSAQNRMQDEPW
VSGVQGAAQNHLHAAAPFWPATRAEAPADTPTPSLSLSASIFGFAVAAVESPSHGLCEQGYRDGGWQLSLCPDTEADRDL
VLSWVINEGSEPVADFLVQPGYSYPAAVESANTQYGTAQDKAKQDEYVRVDFSQGNYSHGLLTFMPPQPNLANRLARELV
LVIDTSGSMAGDSMVQARSALIHALGGLGPQDSFNIIAFSSDARPLWPDAKPATAFNLGAAQQFVRSLEADGGTEMASAL
ELALKTPSVVDEDTKRLRQVLFITDGAVNGEDALFNLIERRLGTSRLFPVAIGAAPNGYFMSRAAAAGRGSFTFIGHGGE
VAEKMNQLLSRIEHPVVSDLSVTWADGSPVDAMPGVLPDLYAGEALNLSLRTVPDALMPIIVKGNTDGQIWERKLTPRAV
PGGSGLDLQYGKARVDDLVRQTLTPSQRRAATVALGLEYHLVTAHTSLVAVDKTRVSHGQGLDARLPEATPHGWQGGRLP
QTASGSLGLMLAGALLVLFAIAAATWRREDEAA

Sequences:

>Translated_753_residues
MKDDKSMYSQRKVVPKVEMKQGLTALAMMALLAAPTVSASSASTVQPVTLPLDGPMAGQGSTSPGDIIAPGHGGELMFED
EGTEQVSLALDTRYTVKVSALVSRVTVSQTFQNQSNRVINGHYRFALAPNAAVSGMRLTIGERLIEGEIQEKAHAERVYE
QAKRDGKRASLVSHSESNLFSTRIANFMPGETLTVSIDYQEILHPQAGRVELRIPTAQTPRYGASAMLPSAQNRMQDEPW
VSGVQGAAQNHLHAAAPFWPATRAEAPADTPTPSLSLSASIFGFAVAAVESPSHGLCEQGYRDGGWQLSLCPDTEADRDL
VLSWVINEGSEPVADFLVQPGYSYPAAVESANTQYGTAQDKAKQDEYVRVDFSQGNYSHGLLTFMPPQPNLANRLARELV
LVIDTSGSMAGDSMVQARSALIHALGGLGPQDSFNIIAFSSDARPLWPDAKPATAFNLGAAQQFVRSLEADGGTEMASAL
ELALKTPSVVDEDTKRLRQVLFITDGAVNGEDALFNLIERRLGTSRLFPVAIGAAPNGYFMSRAAAAGRGSFTFIGHGGE
VAEKMNQLLSRIEHPVVSDLSVTWADGSPVDAMPGVLPDLYAGEALNLSLRTVPDALMPIIVKGNTDGQIWERKLTPRAV
PGGSGLDLQYGKARVDDLVRQTLTPSQRRAATVALGLEYHLVTAHTSLVAVDKTRVSHGQGLDARLPEATPHGWQGGRLP
QTASGSLGLMLAGALLVLFAIAAATWRREDEAA
>Mature_753_residues
MKDDKSMYSQRKVVPKVEMKQGLTALAMMALLAAPTVSASSASTVQPVTLPLDGPMAGQGSTSPGDIIAPGHGGELMFED
EGTEQVSLALDTRYTVKVSALVSRVTVSQTFQNQSNRVINGHYRFALAPNAAVSGMRLTIGERLIEGEIQEKAHAERVYE
QAKRDGKRASLVSHSESNLFSTRIANFMPGETLTVSIDYQEILHPQAGRVELRIPTAQTPRYGASAMLPSAQNRMQDEPW
VSGVQGAAQNHLHAAAPFWPATRAEAPADTPTPSLSLSASIFGFAVAAVESPSHGLCEQGYRDGGWQLSLCPDTEADRDL
VLSWVINEGSEPVADFLVQPGYSYPAAVESANTQYGTAQDKAKQDEYVRVDFSQGNYSHGLLTFMPPQPNLANRLARELV
LVIDTSGSMAGDSMVQARSALIHALGGLGPQDSFNIIAFSSDARPLWPDAKPATAFNLGAAQQFVRSLEADGGTEMASAL
ELALKTPSVVDEDTKRLRQVLFITDGAVNGEDALFNLIERRLGTSRLFPVAIGAAPNGYFMSRAAAAGRGSFTFIGHGGE
VAEKMNQLLSRIEHPVVSDLSVTWADGSPVDAMPGVLPDLYAGEALNLSLRTVPDALMPIIVKGNTDGQIWERKLTPRAV
PGGSGLDLQYGKARVDDLVRQTLTPSQRRAATVALGLEYHLVTAHTSLVAVDKTRVSHGQGLDARLPEATPHGWQGGRLP
QTASGSLGLMLAGALLVLFAIAAATWRREDEAA

Specific function: Unknown

COG id: COG2304

COG function: function code R; Uncharacterized protein containing a von Willebrand factor type A (vWA) domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI38348336, Length=659, Percent_Identity=24.7344461305008, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI210147462, Length=576, Percent_Identity=23.2638888888889, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI112789550, Length=344, Percent_Identity=23.8372093023256, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI31542984, Length=323, Percent_Identity=22.9102167182663, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI262050538, Length=324, Percent_Identity=22.8395061728395, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI133925809, Length=351, Percent_Identity=23.3618233618234, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI156119625, Length=512, Percent_Identity=20.703125, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI222352129, Length=540, Percent_Identity=22.5925925925926, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI261878614, Length=251, Percent_Identity=23.9043824701195, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 80392; Mature: 80392

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50234 VWFA ; PS00697 DNA_LIGASE_A1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDKSMYSQRKVVPKVEMKQGLTALAMMALLAAPTVSASSASTVQPVTLPLDGPMAGQG
CCCHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
STSPGDIIAPGHGGELMFEDEGTEQVSLALDTRYTVKVSALVSRVTVSQTFQNQSNRVIN
CCCCCCEEECCCCCEEEECCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCEEE
GHYRFALAPNAAVSGMRLTIGERLIEGEIQEKAHAERVYEQAKRDGKRASLVSHSESNLF
CEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHH
STRIANFMPGETLTVSIDYQEILHPQAGRVELRIPTAQTPRYGASAMLPSAQNRMQDEPW
HHHHHHCCCCCEEEEEECHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCH
VSGVQGAAQNHLHAAAPFWPATRAEAPADTPTPSLSLSASIFGFAVAAVESPSHGLCEQG
HHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHEEEEEECCCCCCHHHCC
YRDGGWQLSLCPDTEADRDLVLSWVINEGSEPVADFLVQPGYSYPAAVESANTQYGTAQD
CCCCCEEEEECCCCCCCHHEEEEEEECCCCCHHHHHHHCCCCCCCCHHCCCCCCCCCCHH
KAKQDEYVRVDFSQGNYSHGLLTFMPPQPNLANRLARELVLVIDTSGSMAGDSMVQARSA
HCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHEEEEEEECCCCCCCHHHHHHHHH
LIHALGGLGPQDSFNIIAFSSDARPLWPDAKPATAFNLGAAQQFVRSLEADGGTEMASAL
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHH
ELALKTPSVVDEDTKRLRQVLFITDGAVNGEDALFNLIERRLGTSRLFPVAIGAAPNGYF
HHHHCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
MSRAAAAGRGSFTFIGHGGEVAEKMNQLLSRIEHPVVSDLSVTWADGSPVDAMPGVLPDL
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHH
YAGEALNLSLRTVPDALMPIIVKGNTDGQIWERKLTPRAVPGGSGLDLQYGKARVDDLVR
HCCCEEEEEHHHCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
QTLTPSQRRAATVALGLEYHLVTAHTSLVAVDKTRVSHGQGLDARLPEATPHGWQGGRLP
HHCCCCHHCEEEEEEEEEEEEEEECCEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCC
QTASGSLGLMLAGALLVLFAIAAATWRREDEAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKDDKSMYSQRKVVPKVEMKQGLTALAMMALLAAPTVSASSASTVQPVTLPLDGPMAGQG
CCCHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
STSPGDIIAPGHGGELMFEDEGTEQVSLALDTRYTVKVSALVSRVTVSQTFQNQSNRVIN
CCCCCCEEECCCCCEEEECCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCEEE
GHYRFALAPNAAVSGMRLTIGERLIEGEIQEKAHAERVYEQAKRDGKRASLVSHSESNLF
CEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHH
STRIANFMPGETLTVSIDYQEILHPQAGRVELRIPTAQTPRYGASAMLPSAQNRMQDEPW
HHHHHHCCCCCEEEEEECHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCH
VSGVQGAAQNHLHAAAPFWPATRAEAPADTPTPSLSLSASIFGFAVAAVESPSHGLCEQG
HHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCCCCEEHHHHHHEEEEEECCCCCCHHHCC
YRDGGWQLSLCPDTEADRDLVLSWVINEGSEPVADFLVQPGYSYPAAVESANTQYGTAQD
CCCCCEEEEECCCCCCCHHEEEEEEECCCCCHHHHHHHCCCCCCCCHHCCCCCCCCCCHH
KAKQDEYVRVDFSQGNYSHGLLTFMPPQPNLANRLARELVLVIDTSGSMAGDSMVQARSA
HCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHEEEEEEECCCCCCCHHHHHHHHH
LIHALGGLGPQDSFNIIAFSSDARPLWPDAKPATAFNLGAAQQFVRSLEADGGTEMASAL
HHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCHHHHHHH
ELALKTPSVVDEDTKRLRQVLFITDGAVNGEDALFNLIERRLGTSRLFPVAIGAAPNGYF
HHHHCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHH
MSRAAAAGRGSFTFIGHGGEVAEKMNQLLSRIEHPVVSDLSVTWADGSPVDAMPGVLPDL
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHH
YAGEALNLSLRTVPDALMPIIVKGNTDGQIWERKLTPRAVPGGSGLDLQYGKARVDDLVR
HCCCEEEEEHHHCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
QTLTPSQRRAATVALGLEYHLVTAHTSLVAVDKTRVSHGQGLDARLPEATPHGWQGGRLP
HHCCCCHHCEEEEEEEEEEEEEEECCEEEEEECHHHCCCCCCCCCCCCCCCCCCCCCCCC
QTASGSLGLMLAGALLVLFAIAAATWRREDEAA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA