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The map label for this gene is gph2 [H]

Identifier: 119775122

GI number: 119775122

Start: 2414311

End: 2414958

Strand: Reverse

Name: gph2 [H]

Synonym: Sama_1987

Alternate gene names: 119775122

Gene position: 2414958-2414311 (Counterclockwise)

Preceding gene: 119775123

Following gene: 119775120

Centisome position: 56.08

GC content: 53.24

Gene sequence:

>648_bases
ATGCAAAGATTCGACCTGATTATCTTCGATTGGGATGGCACCCTGATGGATTCCATCAGCAAGATAGTCGATTGCATGCA
GGCACTGGCTCAGGAACTTTCCATTGCCGTGCCAACCGAAAAGGCTGTCCGGGACGTGATTGGCCTTTCAATGCCTGAAG
CCATGCGCGCCCTGTTTCCCGCTGAAACTGAGGCAACAAGGGCAGGCTGGATAAACAGGTATAAGGCCCATTACCAGATT
TTTAATGCCACCCCGAGCCCGTTATTTGAGGGGGTGCCTGAGCTGTTGACATCATTGCACGGGGCATCGCGCAAACTGGC
TATTGCCACAGGTAAGGGCAGGGAAGGGTTAAACCGTATTCTGGATGAGACCCGTCTTGGGGACTGTTTCCACGCTTCCC
GCTGCGCCGATGAAACCCAAAGCAAACCCCACCCGCAGATGTTGCATGAATTACTGGCAGAACTTGATGTCAGTCCCGAA
CGTGCGGTGATGATTGGTGATTCGGCATTTGATTTACAGATGGCAAACAACGCGGGTGTTGCAGCCATCGGGGTGGATTA
CGGTACGCACGACAGAGAGACACTGCTGGGTGTTTCGCCCCTTGCAGTAGTGTCTCATCCTCTGGAGATATTGCACCACT
TGCGCTGA

Upstream 100 bases:

>100_bases
TCACCTTTACCCATCCGGAGTCTGAAACCCAGATGACGGTTCAGGCACCACTGGACGGCGATTTAACGGCCGTGCTGGAT
GCGCTGGAGCAAAAAGGCTG

Downstream 100 bases:

>100_bases
TTACGGCACGAGGTCACTCTCAGTTGTTGCACATACTCAACTCAGTAAGCACAGTCTCTGATTTAGCAAGCACAGCATTT
ATTATGTCTTCGATGACTGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP 2; PGPase2 [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MQRFDLIIFDWDGTLMDSISKIVDCMQALAQELSIAVPTEKAVRDVIGLSMPEAMRALFPAETEATRAGWINRYKAHYQI
FNATPSPLFEGVPELLTSLHGASRKLAIATGKGREGLNRILDETRLGDCFHASRCADETQSKPHPQMLHELLAELDVSPE
RAVMIGDSAFDLQMANNAGVAAIGVDYGTHDRETLLGVSPLAVVSHPLEILHHLR

Sequences:

>Translated_215_residues
MQRFDLIIFDWDGTLMDSISKIVDCMQALAQELSIAVPTEKAVRDVIGLSMPEAMRALFPAETEATRAGWINRYKAHYQI
FNATPSPLFEGVPELLTSLHGASRKLAIATGKGREGLNRILDETRLGDCFHASRCADETQSKPHPQMLHELLAELDVSPE
RAVMIGDSAFDLQMANNAGVAAIGVDYGTHDRETLLGVSPLAVVSHPLEILHHLR
>Mature_215_residues
MQRFDLIIFDWDGTLMDSISKIVDCMQALAQELSIAVPTEKAVRDVIGLSMPEAMRALFPAETEATRAGWINRYKAHYQI
FNATPSPLFEGVPELLTSLHGASRKLAIATGKGREGLNRILDETRLGDCFHASRCADETQSKPHPQMLHELLAELDVSPE
RAVMIGDSAFDLQMANNAGVAAIGVDYGTHDRETLLGVSPLAVVSHPLEILHHLR

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23625; Mature: 23625

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRFDLIIFDWDGTLMDSISKIVDCMQALAQELSIAVPTEKAVRDVIGLSMPEAMRALFP
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHCC
AETEATRAGWINRYKAHYQIFNATPSPLFEGVPELLTSLHGASRKLAIATGKGREGLNRI
CCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
LDETRLGDCFHASRCADETQSKPHPQMLHELLAELDVSPERAVMIGDSAFDLQMANNAGV
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCE
AAIGVDYGTHDRETLLGVSPLAVVSHPLEILHHLR
EEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRFDLIIFDWDGTLMDSISKIVDCMQALAQELSIAVPTEKAVRDVIGLSMPEAMRALFP
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHCC
AETEATRAGWINRYKAHYQIFNATPSPLFEGVPELLTSLHGASRKLAIATGKGREGLNRI
CCCHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHH
LDETRLGDCFHASRCADETQSKPHPQMLHELLAELDVSPERAVMIGDSAFDLQMANNAGV
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCEEEEECCCCCE
AAIGVDYGTHDRETLLGVSPLAVVSHPLEILHHLR
EEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]