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The map label for this gene is fabD [H]

Identifier: 119775116

GI number: 119775116

Start: 2409347

End: 2410273

Strand: Reverse

Name: fabD [H]

Synonym: Sama_1981

Alternate gene names: 119775116

Gene position: 2410273-2409347 (Counterclockwise)

Preceding gene: 119775117

Following gene: 119775115

Centisome position: 55.97

GC content: 58.04

Gene sequence:

>927_bases
ATGGATAAATTTGCCTTTGTATTTCCAGGGCAGGGCTCGCAGGCCGTTGGCATGCTGACCGATCTCGCTGCCGAATTTCC
TGTGGTAACCGAAACATTTGCCGAGGCGAGTGCTGCTCTAGGCTACGATCTGTGGGCTCTGGTGCAGGATGGCCCCGCCG
AGCAGCTCAATCAAACTCAAAAGACTCAGCCTGCGCTGCTGACCGCCAGCGTCTCCATTTGGCGCGCCTATCAGGCAAGC
GGCAAGCCGCAGCCTGCAGTGCTTGCCGGTCACAGCCTGGGCGAATACTCTGCGCTGGTGTGCGCCGGTGTTATTCCTTT
TACCGATGCCGTCAAGCTGGTTGAATTGCGTGGTCAACTGATGCAGGCCGCTGTGCCGGAAGGCACGGGTGCCATGTACG
CCATTATCGGATTGGATAACGATGCTATCGCCAAGGCCTGTGAAGAATCAGCCGAAGGCGAAGTAGTGAGCCCGGTTAAC
TTCAACAGCCCCGGCCAGGTGGTGATTGCCGGTAATAAAGACGCCGTTGAGCGCGCCGCTGCCGCATGTAAAGCTGCCGG
TGCCAAGATGGCGGTAGCATTGCCAGTTAGTGTGCCTTCCCACTGCAGCCTGATGAAAGGCGCGGCCGATAAACTCGCCG
AGGCGCTTGCCGCGATCGAATTCAGTGCACCTGCCATTCCGGTTATCAATAACGTGGACGTGCAGGCGCCAACCGACGTA
GCGGCTATCCGTGATGCACTGGTGCGCCAGTTGTATTGCCCGGTTCGCTGGACCGAAACCGTGGAAGCCATGGCCGCCGA
TGGTATTACTCATCTGGTGGAGTGTGGCCCGGGCAAGGTGCTGACCGGCTTGGCCAAACGCATCAACAAATCTGTTTCTG
CACAAGCGGTCAATGACGTAGCAAGCTTTGCTGCGCTGACCGAATAA

Upstream 100 bases:

>100_bases
TGGCGCCGGTTTTGCCTGGGGTAGTGCGCTGGTGCGCTTCTAATTTCCCCGGGAATTCTGCTAGGCTTTTTACGCTTTTA
CTCAAAAAGGTTTAATAACA

Downstream 100 bases:

>100_bases
AGGAGTTTTCCATGTCTGTATCTTTGGATCTGACCGGCAAGGTAGCCCTGGTTACCGGTGCCAGCCGCGGTATCGGTAAA
GCCATCGCACTGACCCTGGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MDKFAFVFPGQGSQAVGMLTDLAAEFPVVTETFAEASAALGYDLWALVQDGPAEQLNQTQKTQPALLTASVSIWRAYQAS
GKPQPAVLAGHSLGEYSALVCAGVIPFTDAVKLVELRGQLMQAAVPEGTGAMYAIIGLDNDAIAKACEESAEGEVVSPVN
FNSPGQVVIAGNKDAVERAAAACKAAGAKMAVALPVSVPSHCSLMKGAADKLAEALAAIEFSAPAIPVINNVDVQAPTDV
AAIRDALVRQLYCPVRWTETVEAMAADGITHLVECGPGKVLTGLAKRINKSVSAQAVNDVASFAALTE

Sequences:

>Translated_308_residues
MDKFAFVFPGQGSQAVGMLTDLAAEFPVVTETFAEASAALGYDLWALVQDGPAEQLNQTQKTQPALLTASVSIWRAYQAS
GKPQPAVLAGHSLGEYSALVCAGVIPFTDAVKLVELRGQLMQAAVPEGTGAMYAIIGLDNDAIAKACEESAEGEVVSPVN
FNSPGQVVIAGNKDAVERAAAACKAAGAKMAVALPVSVPSHCSLMKGAADKLAEALAAIEFSAPAIPVINNVDVQAPTDV
AAIRDALVRQLYCPVRWTETVEAMAADGITHLVECGPGKVLTGLAKRINKSVSAQAVNDVASFAALTE
>Mature_308_residues
MDKFAFVFPGQGSQAVGMLTDLAAEFPVVTETFAEASAALGYDLWALVQDGPAEQLNQTQKTQPALLTASVSIWRAYQAS
GKPQPAVLAGHSLGEYSALVCAGVIPFTDAVKLVELRGQLMQAAVPEGTGAMYAIIGLDNDAIAKACEESAEGEVVSPVN
FNSPGQVVIAGNKDAVERAAAACKAAGAKMAVALPVSVPSHCSLMKGAADKLAEALAAIEFSAPAIPVINNVDVQAPTDV
AAIRDALVRQLYCPVRWTETVEAMAADGITHLVECGPGKVLTGLAKRINKSVSAQAVNDVASFAALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=311, Percent_Identity=33.1189710610932, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=42.7272727272727, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=71.7532467532468, Blast_Score=425, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71984332, Length=295, Percent_Identity=30.5084745762712, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=28.5234899328859, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24665753, Length=314, Percent_Identity=33.1210191082803, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31764; Mature: 31764

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFAFVFPGQGSQAVGMLTDLAAEFPVVTETFAEASAALGYDLWALVQDGPAEQLNQTQ
CCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHH
KTQPALLTASVSIWRAYQASGKPQPAVLAGHSLGEYSALVCAGVIPFTDAVKLVELRGQL
CCCCEEEEHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MQAAVPEGTGAMYAIIGLDNDAIAKACEESAEGEVVSPVNFNSPGQVVIAGNKDAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCSLMKGAADKLAEALAAIEFSAPAIPVINNVDVQAPTDV
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHH
AAIRDALVRQLYCPVRWTETVEAMAADGITHLVECGPGKVLTGLAKRINKSVSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASFAALTE
HHHHHHCC
>Mature Secondary Structure
MDKFAFVFPGQGSQAVGMLTDLAAEFPVVTETFAEASAALGYDLWALVQDGPAEQLNQTQ
CCCEEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHEEECCCCHHHHHHHH
KTQPALLTASVSIWRAYQASGKPQPAVLAGHSLGEYSALVCAGVIPFTDAVKLVELRGQL
CCCCEEEEHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHH
MQAAVPEGTGAMYAIIGLDNDAIAKACEESAEGEVVSPVNFNSPGQVVIAGNKDAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCSLMKGAADKLAEALAAIEFSAPAIPVINNVDVQAPTDV
HHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCHH
AAIRDALVRQLYCPVRWTETVEAMAADGITHLVECGPGKVLTGLAKRINKSVSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASFAALTE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]