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The map label for this gene is nreC [H]

Identifier: 119775008

GI number: 119775008

Start: 2286764

End: 2287411

Strand: Direct

Name: nreC [H]

Synonym: Sama_1873

Alternate gene names: 119775008

Gene position: 2286764-2287411 (Clockwise)

Preceding gene: 119775007

Following gene: 119775009

Centisome position: 53.1

GC content: 44.44

Gene sequence:

>648_bases
ATGAAAAGTAACAATAGCGTCGTATTGGTAGATGATCATGAACTGGTTCGCGCTGGAATACGCACCTTATTACATACCAT
TGACTCAATCGAAGTGATTGGTGAATGTGGGGATGGCCTCGAGGCAGTGGCATTGGTAAGGCGGCTTAAGCCCAAGCTGC
TGGTATTGGACATCTCGATTAAAAGCTTAAGTGGAATGGAAGTTGTCAAACTGATTTCAAACCAGGCAATACCGGTAAAG
ATCTTAATTCTTTCCATGCACAATAACGTCGAATATGTGGCCAAATGCTTAAAAAACGGGGCACATGGTTATCTCTTAAA
AGATGCTGCGGTCGATGAGCTTGAGCCGGCTATCACAAACGTCCTGCTGGGCCACAGCTACATCAGCAAAGAAATTGATA
TCAGCCTCCTGGAGCAATTACTGTCTACCAATCAATCGGCTCCATCCCTGCTTGAACTCTTAACCAACAGGCAAAAGCAA
ATCCTTCAGCTCATAGCTGAAGGTTATTCCACACGACAAATTGCCGAGTCTATCAGTGTCAGTATCAAGACGGTCGAGAC
ACACAGGGCCCACATAATGGCAAGATTACAAATTTTTGATATTGCGGGACTGGTACGATTTGCGTTACAAGAAAAACTTA
TCCCCTGA

Upstream 100 bases:

>100_bases
GGCCTATTGGGTATTGAGGAGCGGGTAAAGTCCCAAAACGGTAATTTGAATATCAAAGCCATTCCCCATGGCGGAGTCTC
CATTTCAGTTGAGTTTCCTT

Downstream 100 bases:

>100_bases
AACGACAACATGCTTAACATCAAGCGTGTTATGTAAATGAATAATAATACCTTTCGCTAACTCCCATTGCCGGTTGGGTG
TGTTGCAGTGAACCTCATGG

Product: response regulator receiver protein

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKSNNSVVLVDDHELVRAGIRTLLHTIDSIEVIGECGDGLEAVALVRRLKPKLLVLDISIKSLSGMEVVKLISNQAIPVK
ILILSMHNNVEYVAKCLKNGAHGYLLKDAAVDELEPAITNVLLGHSYISKEIDISLLEQLLSTNQSAPSLLELLTNRQKQ
ILQLIAEGYSTRQIAESISVSIKTVETHRAHIMARLQIFDIAGLVRFALQEKLIP

Sequences:

>Translated_215_residues
MKSNNSVVLVDDHELVRAGIRTLLHTIDSIEVIGECGDGLEAVALVRRLKPKLLVLDISIKSLSGMEVVKLISNQAIPVK
ILILSMHNNVEYVAKCLKNGAHGYLLKDAAVDELEPAITNVLLGHSYISKEIDISLLEQLLSTNQSAPSLLELLTNRQKQ
ILQLIAEGYSTRQIAESISVSIKTVETHRAHIMARLQIFDIAGLVRFALQEKLIP
>Mature_215_residues
MKSNNSVVLVDDHELVRAGIRTLLHTIDSIEVIGECGDGLEAVALVRRLKPKLLVLDISIKSLSGMEVVKLISNQAIPVK
ILILSMHNNVEYVAKCLKNGAHGYLLKDAAVDELEPAITNVLLGHSYISKEIDISLLEQLLSTNQSAPSLLELLTNRQKQ
ILQLIAEGYSTRQIAESISVSIKTVETHRAHIMARLQIFDIAGLVRFALQEKLIP

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=34.9282296650718, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1788521, Length=192, Percent_Identity=31.7708333333333, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790102, Length=201, Percent_Identity=32.3383084577114, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1788712, Length=208, Percent_Identity=27.8846153846154, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787473, Length=183, Percent_Identity=30.0546448087432, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1786747, Length=209, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788546, Length=208, Percent_Identity=25.9615384615385, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082052, Length=158, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23685; Mature: 23685

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNNSVVLVDDHELVRAGIRTLLHTIDSIEVIGECGDGLEAVALVRRLKPKLLVLDISI
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC
KSLSGMEVVKLISNQAIPVKILILSMHNNVEYVAKCLKNGAHGYLLKDAAVDELEPAITN
CCCCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VLLGHSYISKEIDISLLEQLLSTNQSAPSLLELLTNRQKQILQLIAEGYSTRQIAESISV
HHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SIKTVETHRAHIMARLQIFDIAGLVRFALQEKLIP
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSNNSVVLVDDHELVRAGIRTLLHTIDSIEVIGECGDGLEAVALVRRLKPKLLVLDISI
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEC
KSLSGMEVVKLISNQAIPVKILILSMHNNVEYVAKCLKNGAHGYLLKDAAVDELEPAITN
CCCCHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCHHHHHHHHHH
VLLGHSYISKEIDISLLEQLLSTNQSAPSLLELLTNRQKQILQLIAEGYSTRQIAESISV
HHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SIKTVETHRAHIMARLQIFDIAGLVRFALQEKLIP
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]