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The map label for this gene is fadE [H]

Identifier: 119775005

GI number: 119775005

Start: 2278706

End: 2281153

Strand: Direct

Name: fadE [H]

Synonym: Sama_1870

Alternate gene names: 119775005

Gene position: 2278706-2281153 (Clockwise)

Preceding gene: 119775003

Following gene: 119775007

Centisome position: 52.92

GC content: 56.54

Gene sequence:

>2448_bases
GTGACTACCCTACTTTGGAGTATCGCGCTGCTTGTGGTGCTTGGTGCCTGCGCTTATTTGCGGGTGTCATTGCTGACCGC
CACGGCCGCAGCCGCCATTATGTTGACCGCAGGATGGACCTTGGATGTTGTTGGCCTTTGGGGCGGCATCATCTTTTTGA
TTATCGCCCTTCCTCTGAATATCAGCAGTATTCGTCAGAGCCTGATCACCCGCCCGCTGCTGAAAGTTTACCGAGGCATC
ATGCCCGAGATGTCTTCCACTGAAAAAGAAGCCATCGACGCCGGTACCACCTGGTGGGAAGCCGATCTGTTCGCCGGTAA
TCCTAACTGGAAGAAGCTGCACAATTACCCGACCGCCCGCCTTTCTGCCGAAGAACAGGCCTTTATCGACGGCCCGGTTA
ACGAAGTGTGCCGCATGGTGAACGAGCATCAGGTATCCCATCAGTTCGCTGACCTGCCTGCTGACGTGTGGCAGTACCTG
AAAGACAACGGCTTCTTCGCGATGATCATCAAGAAGAAGTACGGTGGTCTTGAGTTCTCCGCCTACGCCCAATCCCGCGT
ACTGCAAAAGCTGGCTGGTGTTTCCAGCGAGCTGGCATCCACCGTGGGCGTACCAAACTCCCTCGGCCCTGGTGAACTGT
TGCAGCACTACGGTACGGCCGAGCAGCAGGACCACTACCTGCCACGTCTGGCCAAGGGTCTTGAAGTACCTTGTTTTGCC
CTGACCAGCCCGGAAGCCGGTTCTGATGCAGGCTCAATTCCTGACTACGGTGTTGTCTGCAAAGGCATGTGGAAAGGTGA
AGAAGTGCTGGGTATGAAGCTCACCTGGAACAAGCGCTACATCACCCTGGCTCCTATCGCGACTGTGCTTGGTCTGGCGT
TCAAACTGCGTGACCCTGAGCGTCTGCTTGGCGGCGAAGAAGAGCTCGGCATCACCTGTGCCCTTATTCCTACCGATGTG
GAAGGCGTGGAAACCGGTCGTCGTCACTTCCCACTCAACTGTATGTTCCAAAACGGCCCAACCCGCGGTAAAGACGTGTT
TGTGCCCTTAAGCTTTATCATTGGCGGCCCGAAAATGGCCGGTCAGGGCTGGCGTATGCTGGTGGAATGTTTGTCGGTTG
GCCGCGGCATTACCCTGCCATCCAACTCTGCCGGTGGCGTGAAAACTGCTGCACTGGCAACCGGCGCCTATGCCCGCATC
CGCCGACAGTTCAAGCTGCCTATCGGTAAGCTGGAAGGTATTGAAGAGCCAATGGCGCGCATCGGCGGTAACGCCTATCT
GATGGACGCTGTGACCTCGCTGACCACCACAGGTATCGATCTGGGTGAAAAGCCATCGGTTATCTCGGCCATCGTGAAGT
ATCACCTCACCGATCGTATGCAGAAATGCGTAATCGACGCCATGGACATCCACGGCGGTAAAGGCGTGTGCCTTGGCCCC
AACAACTACCTGGGCCGTGGTTATCAGGCTGCGCCTATTGCCATTACCGTGGAAGGCGCCAACATCCTCACCCGCTCTAT
GATCATCTATGGTCAGGGCGCCATTCGCTGCCATCCATACGTACTGGCCGAAATGGACTCTGCCTTCGATAAAGACGTGC
GTCAGGGCCTGAATAAGTTCGATGCGGCTCTCTTTGGCCATATCGGCTTTACTATCAGCAATCTGATTCGCAGTGTGTGG
ATGGGCCTGACTGGCAGCCGCTTCTCTAACGCGCCATACGGCGACAAGACCAAGCGCTACTACCAGCACATGAACCGTTT
CAGTGCCAACCTGGCGTTGCTGTCTGATCTGGCCATGGCCACCCTGGGCGGAAACCTGAAGCGTAAAGAGCGTATCTCTG
CCCGTCTTGGCGATATGCTCAGTCAGCTGTATCTGGCCTCCGCCACCTTGAAACGTTATCAGGATGAAGGCCGTCAAACT
GAAGATCTGCCGCTGGTACAGTGGGCGGTTGAAGATGCCCTGTTCAAACTGCAAGCCTCTTTGGATGAGCTGCTGGACAA
CTTCCCTGCCGGTCTGGGCGGCGTGCTGCGCGTATTGCTGCTGCCTTTCGGTCGTCCACTGAAGCGTCCAAGCGATGTAC
TGGACCACAAGGTTGCCAAAATCATGCAAACCCCTTGTGCCAGCCGTGAGCGTCTGGGTCAGGGCCAGTTCTGGGAAGCC
TGCGACAACAACCCTGTGGGTGTTCAGGAACAGACTTTCAAGGACATCCTTGCCGCTGAGCCCCTGTACGACAAGGTATG
CAAAGCTGCCGGTAAGCGTCTGCCCTTCATGTGGCTGGATCAGGTGGCTGCCGAAGGTAAGGCACTGGGCATTCTGTCTG
ATGCCGAGATCGCCCTGCTGGAGAAAGCCGAGATTGGCCGTATGAAGTCTATCAACGTAGACGACTTCGACCCAGCCGAG
CTGGTGGCGCAAACCACCACTGGCAAGTCTCAGGAGCAAGCGGCGTAA

Upstream 100 bases:

>100_bases
ACTTTTTAATGCGACACAGGTCTGACCACACACTATACTTGTGATCAGGATCGCTTATATGACCCGCCTGGAGAAGGGTT
ATGAATAAAGGAGAACGAGA

Downstream 100 bases:

>100_bases
GTGCTGCGACTCCAGATAAAAAAGGCGCCTCTGGGCGCCTTTTCTGTTATTGCTGATTGCAACAGTGGATCAAGTGGTCG
TCGGACTCCTGCTTAGATAT

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTTLLWSIALLVVLGACAYLRVSLLTATAAAAIMLTAGWTLDVVGLWGGIIFLIIALPLNISSIRQSLITRPLLKVYRGI
MPEMSSTEKEAIDAGTTWWEADLFAGNPNWKKLHNYPTARLSAEEQAFIDGPVNEVCRMVNEHQVSHQFADLPADVWQYL
KDNGFFAMIIKKKYGGLEFSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTAEQQDHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDYGVVCKGMWKGEEVLGMKLTWNKRYITLAPIATVLGLAFKLRDPERLLGGEEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMDSAFDKDVRQGLNKFDAALFGHIGFTISNLIRSVW
MGLTGSRFSNAPYGDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDMLSQLYLASATLKRYQDEGRQT
EDLPLVQWAVEDALFKLQASLDELLDNFPAGLGGVLRVLLLPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGQGQFWEA
CDNNPVGVQEQTFKDILAAEPLYDKVCKAAGKRLPFMWLDQVAAEGKALGILSDAEIALLEKAEIGRMKSINVDDFDPAE
LVAQTTTGKSQEQAA

Sequences:

>Translated_815_residues
MTTLLWSIALLVVLGACAYLRVSLLTATAAAAIMLTAGWTLDVVGLWGGIIFLIIALPLNISSIRQSLITRPLLKVYRGI
MPEMSSTEKEAIDAGTTWWEADLFAGNPNWKKLHNYPTARLSAEEQAFIDGPVNEVCRMVNEHQVSHQFADLPADVWQYL
KDNGFFAMIIKKKYGGLEFSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTAEQQDHYLPRLAKGLEVPCFA
LTSPEAGSDAGSIPDYGVVCKGMWKGEEVLGMKLTWNKRYITLAPIATVLGLAFKLRDPERLLGGEEELGITCALIPTDV
EGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMDSAFDKDVRQGLNKFDAALFGHIGFTISNLIRSVW
MGLTGSRFSNAPYGDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDMLSQLYLASATLKRYQDEGRQT
EDLPLVQWAVEDALFKLQASLDELLDNFPAGLGGVLRVLLLPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGQGQFWEA
CDNNPVGVQEQTFKDILAAEPLYDKVCKAAGKRLPFMWLDQVAAEGKALGILSDAEIALLEKAEIGRMKSINVDDFDPAE
LVAQTTTGKSQEQAA
>Mature_814_residues
TTLLWSIALLVVLGACAYLRVSLLTATAAAAIMLTAGWTLDVVGLWGGIIFLIIALPLNISSIRQSLITRPLLKVYRGIM
PEMSSTEKEAIDAGTTWWEADLFAGNPNWKKLHNYPTARLSAEEQAFIDGPVNEVCRMVNEHQVSHQFADLPADVWQYLK
DNGFFAMIIKKKYGGLEFSAYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTAEQQDHYLPRLAKGLEVPCFAL
TSPEAGSDAGSIPDYGVVCKGMWKGEEVLGMKLTWNKRYITLAPIATVLGLAFKLRDPERLLGGEEELGITCALIPTDVE
GVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMAGQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIR
RQFKLPIGKLEGIEEPMARIGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGPN
NYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMDSAFDKDVRQGLNKFDAALFGHIGFTISNLIRSVWM
GLTGSRFSNAPYGDKTKRYYQHMNRFSANLALLSDLAMATLGGNLKRKERISARLGDMLSQLYLASATLKRYQDEGRQTE
DLPLVQWAVEDALFKLQASLDELLDNFPAGLGGVLRVLLLPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGQGQFWEAC
DNNPVGVQEQTFKDILAAEPLYDKVCKAAGKRLPFMWLDQVAAEGKALGILSDAEIALLEKAEIGRMKSINVDDFDPAEL
VAQTTTGKSQEQAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=550, Percent_Identity=25.6363636363636, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4557235, Length=407, Percent_Identity=24.5700245700246, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=24.8704663212435, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI87081702, Length=807, Percent_Identity=66.0470879801735, Blast_Score=1108, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=357, Percent_Identity=24.3697478991597, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=323, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=371, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=309, Percent_Identity=26.537216828479, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363737, Length=476, Percent_Identity=25.8403361344538, Blast_Score=83, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24646207, Length=328, Percent_Identity=25.3048780487805, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 88865; Mature: 88734

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLWSIALLVVLGACAYLRVSLLTATAAAAIMLTAGWTLDVVGLWGGIIFLIIALPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
ISSIRQSLITRPLLKVYRGIMPEMSSTEKEAIDAGTTWWEADLFAGNPNWKKLHNYPTAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECEEECCCCCHHHHHCCCCHH
LSAEEQAFIDGPVNEVCRMVNEHQVSHQFADLPADVWQYLKDNGFFAMIIKKKYGGLEFS
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCHH
AYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTAEQQDHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDYGVVCKGMWKGEEVLGMKLTWNKRYITLAPIATVLGLAFKLRDPE
ECCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCHH
RLLGGEEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMA
HHHCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
HCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMDSAFDKDVRQGLNKF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHH
DAALFGHIGFTISNLIRSVWMGLTGSRFSNAPYGDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDMLSQLYLASATLKRYQDEGRQTEDLPLVQWAVEDALFKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDELLDNFPAGLGGVLRVLLLPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGQGQFWEA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHH
CDNNPVGVQEQTFKDILAAEPLYDKVCKAAGKRLPFMWLDQVAAEGKALGILSDAEIALL
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCHHHHH
EKAEIGRMKSINVDDFDPAELVAQTTTGKSQEQAA
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHCCC
>Mature Secondary Structure 
TTLLWSIALLVVLGACAYLRVSLLTATAAAAIMLTAGWTLDVVGLWGGIIFLIIALPLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
ISSIRQSLITRPLLKVYRGIMPEMSSTEKEAIDAGTTWWEADLFAGNPNWKKLHNYPTAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECEEECCCCCHHHHHCCCCHH
LSAEEQAFIDGPVNEVCRMVNEHQVSHQFADLPADVWQYLKDNGFFAMIIKKKYGGLEFS
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCCHH
AYAQSRVLQKLAGVSSELASTVGVPNSLGPGELLQHYGTAEQQDHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEE
LTSPEAGSDAGSIPDYGVVCKGMWKGEEVLGMKLTWNKRYITLAPIATVLGLAFKLRDPE
ECCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCCEEEHHHHHHHHHHHHHCCCHH
RLLGGEEELGITCALIPTDVEGVETGRRHFPLNCMFQNGPTRGKDVFVPLSFIIGGPKMA
HHHCCCHHCCEEEEEECCCCCHHHCCCCCCCEEEEECCCCCCCCEEEEEHHHHCCCCCCC
GQGWRMLVECLSVGRGITLPSNSAGGVKTAALATGAYARIRRQFKLPIGKLEGIEEPMAR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTSLTTTGIDLGEKPSVISAIVKYHLTDRMQKCVIDAMDIHGGKGVCLGP
HCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMDSAFDKDVRQGLNKF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHH
DAALFGHIGFTISNLIRSVWMGLTGSRFSNAPYGDKTKRYYQHMNRFSANLALLSDLAMA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDMLSQLYLASATLKRYQDEGRQTEDLPLVQWAVEDALFKLQAS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDELLDNFPAGLGGVLRVLLLPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGQGQFWEA
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHH
CDNNPVGVQEQTFKDILAAEPLYDKVCKAAGKRLPFMWLDQVAAEGKALGILSDAEIALL
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCHHHHH
EKAEIGRMKSINVDDFDPAELVAQTTTGKSQEQAA
HHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]