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The map label for this gene is pgl [H]

Identifier: 119774946

GI number: 119774946

Start: 2204856

End: 2205554

Strand: Reverse

Name: pgl [H]

Synonym: Sama_1811

Alternate gene names: 119774946

Gene position: 2205554-2204856 (Counterclockwise)

Preceding gene: 119774947

Following gene: 119774945

Centisome position: 51.22

GC content: 54.08

Gene sequence:

>699_bases
GTGCTGAAAGAAGCGGTATTCAAATCATTCGATAACACTGATTCGCTGGAAACCCAGTTGGCAGACCGTATCGCGCGCCA
ACTGCAGGATGCGGTGGATGCCCGCGGCAAGGCGAGCCTGGTGGTAAGTGGCGGCTCCACGCCGCTCAAACTGTTCAAGG
CCTTGTCCAATAAAGCCATCGACTGGAACGAGGTCTTTGTTACGCTCGCCGATGAGCGCTGGGTAGACAACGCCCATAAG
GACTCCAACGAGCGTCTGGTGCGTGAAAATTTGCTGCAAAACCGTGCCGCATCAGCCAAATTTCGCGGCCTTAAAAATAT
GTTTGCCAGTGCAGAAGAGGGCGCAGCCATGACTTCTGAACATCTGGCCAACGTGCCACGCCCGTTCGATGTGGTTGTAT
TGGGGATGGGCAACGATGGACACACCTGTTCCTGGTTCCCATGCTCTGACGACCTGATGCGGGCACTGGACAGTGACGCT
TTGTGTGAAGCCGTGACACCAAGAACGGCGCCACATGAGCGGATCACTCTGACCAAAAAAGCGATTCTCAACAGCCGCCA
AATCTATTTGCATCTGGTGGGCGAACAAAAGCTCAGCGTCTATCGTCAGGCGCTCGAAAGCGACGATATAAAAGCGATGC
CAATTCGAGTGGTATTGGGTCAACACAAAACCCCGGTCGACGTGTATTGGAGCGCTTAA

Upstream 100 bases:

>100_bases
GAAAGACCGAAAGCCTATCCTGCGGGCACCTGGGGGCCGGTGGCCTCGGTAGCGCTCATCACCAAAGATGGGCGTTCCTG
GGATGAATAAGGAGGCCAAG

Downstream 100 bases:

>100_bases
GGAGGCAAGTTATGCACCCCGTAGTCAAATCGGTGACCGACAGGATCATCGAACGCAGTAAAGAAAGTCGCAGTGCTTAT
CTGGCCGCGCTGCAGGAAGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLKEAVFKSFDNTDSLETQLADRIARQLQDAVDARGKASLVVSGGSTPLKLFKALSNKAIDWNEVFVTLADERWVDNAHK
DSNERLVRENLLQNRAASAKFRGLKNMFASAEEGAAMTSEHLANVPRPFDVVVLGMGNDGHTCSWFPCSDDLMRALDSDA
LCEAVTPRTAPHERITLTKKAILNSRQIYLHLVGEQKLSVYRQALESDDIKAMPIRVVLGQHKTPVDVYWSA

Sequences:

>Translated_232_residues
MLKEAVFKSFDNTDSLETQLADRIARQLQDAVDARGKASLVVSGGSTPLKLFKALSNKAIDWNEVFVTLADERWVDNAHK
DSNERLVRENLLQNRAASAKFRGLKNMFASAEEGAAMTSEHLANVPRPFDVVVLGMGNDGHTCSWFPCSDDLMRALDSDA
LCEAVTPRTAPHERITLTKKAILNSRQIYLHLVGEQKLSVYRQALESDDIKAMPIRVVLGQHKTPVDVYWSA
>Mature_232_residues
MLKEAVFKSFDNTDSLETQLADRIARQLQDAVDARGKASLVVSGGSTPLKLFKALSNKAIDWNEVFVTLADERWVDNAHK
DSNERLVRENLLQNRAASAKFRGLKNMFASAEEGAAMTSEHLANVPRPFDVVVLGMGNDGHTCSWFPCSDDLMRALDSDA
LCEAVTPRTAPHERITLTKKAILNSRQIYLHLVGEQKLSVYRQALESDDIKAMPIRVVLGQHKTPVDVYWSA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=198, Percent_Identity=28.7878787878788, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115533060, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115533058, Length=202, Percent_Identity=28.2178217821782, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321957, Length=226, Percent_Identity=24.7787610619469, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25810; Mature: 25810

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKEAVFKSFDNTDSLETQLADRIARQLQDAVDARGKASLVVSGGSTPLKLFKALSNKAI
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCC
DWNEVFVTLADERWVDNAHKDSNERLVRENLLQNRAASAKFRGLKNMFASAEEGAAMTSE
CHHHEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
HLANVPRPFDVVVLGMGNDGHTCSWFPCSDDLMRALDSDALCEAVTPRTAPHERITLTKK
HHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHH
AILNSRQIYLHLVGEQKLSVYRQALESDDIKAMPIRVVLGQHKTPVDVYWSA
HHHCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECC
>Mature Secondary Structure
MLKEAVFKSFDNTDSLETQLADRIARQLQDAVDARGKASLVVSGGSTPLKLFKALSNKAI
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCC
DWNEVFVTLADERWVDNAHKDSNERLVRENLLQNRAASAKFRGLKNMFASAEEGAAMTSE
CHHHEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
HLANVPRPFDVVVLGMGNDGHTCSWFPCSDDLMRALDSDALCEAVTPRTAPHERITLTKK
HHHCCCCCEEEEEEEECCCCCEEEEECCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHH
AILNSRQIYLHLVGEQKLSVYRQALESDDIKAMPIRVVLGQHKTPVDVYWSA
HHHCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]