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The map label for this gene is hmrR2 [H]

Identifier: 119774920

GI number: 119774920

Start: 2177393

End: 2177797

Strand: Reverse

Name: hmrR2 [H]

Synonym: Sama_1785

Alternate gene names: 119774920

Gene position: 2177797-2177393 (Counterclockwise)

Preceding gene: 119774921

Following gene: 119774918

Centisome position: 50.57

GC content: 46.17

Gene sequence:

>405_bases
ATGAGTACCCTACTGACTATTGGAGAGGCTGCCAAAACGAGTGGACTCTCTACCAAGATGATACGTCACTATGAGCAAAC
AGGATTACTGAAGAAATCCCCCCGAACTGACTCGGGATATCGCCTGTATAACAACGAGCAAATCAATCAGCTCAGATTTA
TCAGGCAAGCCCGAAACCTGGGATTTTCATTGAATGACATCCAATCCCTCCTTGGCCTGTGGCAAGACCCAAACAGGGAA
AGCCGATTGGTCAAACAACTCGCAACCCAGCACCTGGACGACATAAAAATGAAAATCAGCGAGTTGCAACATATGCAGCT
CATACTCACAGAGCTGGCAGAAAGTTGCTGTGGGGATGAAAATCCACACTGTAGTATTTTGCAAAAGCTCGCAAAACCGG
ATTAA

Upstream 100 bases:

>100_bases
CTGAACCCGGTTATTGCTGGTGCAGCTATGGCATGTAGCAGTGTATTGGTAATCAGTAATGCTTTACGCCTGCAGCGTAA
AAGCTTCTAGGAGGTGTAAG

Downstream 100 bases:

>100_bases
CAGACCTTGCTAACCTAAACGTGGCAACCCGCCCAATCGACGTCCGGCATCAGTGTCGGTTTTCCGTTTAGCGCTCATTT
CCTAAGCTTCAGACACTTAT

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MSTLLTIGEAAKTSGLSTKMIRHYEQTGLLKKSPRTDSGYRLYNNEQINQLRFIRQARNLGFSLNDIQSLLGLWQDPNRE
SRLVKQLATQHLDDIKMKISELQHMQLILTELAESCCGDENPHCSILQKLAKPD

Sequences:

>Translated_134_residues
MSTLLTIGEAAKTSGLSTKMIRHYEQTGLLKKSPRTDSGYRLYNNEQINQLRFIRQARNLGFSLNDIQSLLGLWQDPNRE
SRLVKQLATQHLDDIKMKISELQHMQLILTELAESCCGDENPHCSILQKLAKPD
>Mature_133_residues
STLLTIGEAAKTSGLSTKMIRHYEQTGLLKKSPRTDSGYRLYNNEQINQLRFIRQARNLGFSLNDIQSLLGLWQDPNRES
RLVKQLATQHLDDIKMKISELQHMQLILTELAESCCGDENPHCSILQKLAKPD

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=38.5826771653543, Blast_Score=101, Evalue=1e-23,
Organism=Escherichia coli, GI1789687, Length=130, Percent_Identity=37.6923076923077, Blast_Score=95, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15296; Mature: 15165

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLLTIGEAAKTSGLSTKMIRHYEQTGLLKKSPRTDSGYRLYNNEQINQLRFIRQARNL
CCCHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHC
GFSLNDIQSLLGLWQDPNRESRLVKQLATQHLDDIKMKISELQHMQLILTELAESCCGDE
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPHCSILQKLAKPD
CCCHHHHHHHCCCC
>Mature Secondary Structure 
STLLTIGEAAKTSGLSTKMIRHYEQTGLLKKSPRTDSGYRLYNNEQINQLRFIRQARNL
CCHHHCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHC
GFSLNDIQSLLGLWQDPNRESRLVKQLATQHLDDIKMKISELQHMQLILTELAESCCGDE
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NPHCSILQKLAKPD
CCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]