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The map label for this gene is lolA

Identifier: 119774908

GI number: 119774908

Start: 2168820

End: 2169431

Strand: Direct

Name: lolA

Synonym: Sama_1773

Alternate gene names: 119774908

Gene position: 2168820-2169431 (Clockwise)

Preceding gene: 119774907

Following gene: 119774909

Centisome position: 50.37

GC content: 49.02

Gene sequence:

>612_bases
TTGAAAAAGTCGATTGTAGTGCTCTTTTCTGCCGTGCTGCCTTTTGCGGTCTTCGCAGATGATGCCAAAGAACTGGTATC
CAAATTGGATGTGATGCAGGGCATTAAGGCCAACTTCAGCCAGAAAGTAACAGATCAGAATGGCAAACTCATCCAGGAAG
GCAGTGGTGTGATTGCCATGCATCAACCCGATGCATTTTACTGGCATCTCACAGCCCCCGACGAATCTCTGATAGTGGCC
AAAGACAATAGTGTCTGGGTGTATAACCCCTTTGCCGAAGAAGTCAGTATCCTGGATATGGAGGATATTCTTAAGGCTTC
ACCCATGGCGCTGTTGGTGCATCGTGATGAAAAACGCTGGAATGAATATCAGATTGATAGAAAAGGCAGTTGCTTTGATA
TCACGCCACGTCAGGGCGTTGAAAGTGCCGTCGATACTGTCTCTGTCTGTTTTGCAAATAATACGCTCTCTGACATTCGC
CTGACGGATGCCCAGGGCAGCACCAGCCACTTTTCGCTGTCTGAGCAAGCGGCAGTGACCGATGCCGACGAGAGCCTATT
TCAGTTTCAGATCCCCGATGGCGTCAGCATTGACGATCAGCGTCGTCAGTAA

Upstream 100 bases:

>100_bases
GGCACCACCACCGCCACGAAACTAAGCCAGCCCTGACCCGGTGTTGTTCTGAAGTGAATTTACCGGGTTTGAAATCGTTT
AACGTTGATGAGGTTAGTAT

Downstream 100 bases:

>100_bases
AAGGATGCGCTGTGTCGTTGAGTTTTGATTTCAGCCCCGACTTCAACCCACTGGCTGCCCGTATGCGTCCGGCCAGTGTT
GAGGAGTATATAGGTCAGTC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKKSIVVLFSAVLPFAVFADDAKELVSKLDVMQGIKANFSQKVTDQNGKLIQEGSGVIAMHQPDAFYWHLTAPDESLIVA
KDNSVWVYNPFAEEVSILDMEDILKASPMALLVHRDEKRWNEYQIDRKGSCFDITPRQGVESAVDTVSVCFANNTLSDIR
LTDAQGSTSHFSLSEQAAVTDADESLFQFQIPDGVSIDDQRRQ

Sequences:

>Translated_203_residues
MKKSIVVLFSAVLPFAVFADDAKELVSKLDVMQGIKANFSQKVTDQNGKLIQEGSGVIAMHQPDAFYWHLTAPDESLIVA
KDNSVWVYNPFAEEVSILDMEDILKASPMALLVHRDEKRWNEYQIDRKGSCFDITPRQGVESAVDTVSVCFANNTLSDIR
LTDAQGSTSHFSLSEQAAVTDADESLFQFQIPDGVSIDDQRRQ
>Mature_203_residues
MKKSIVVLFSAVLPFAVFADDAKELVSKLDVMQGIKANFSQKVTDQNGKLIQEGSGVIAMHQPDAFYWHLTAPDESLIVA
KDNSVWVYNPFAEEVSILDMEDILKASPMALLVHRDEKRWNEYQIDRKGSCFDITPRQGVESAVDTVSVCFANNTLSDIR
LTDAQGSTSHFSLSEQAAVTDADESLFQFQIPDGVSIDDQRRQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=205, Percent_Identity=32.6829268292683, Blast_Score=123, Evalue=9e-30,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_SHEAM (A1S6H2)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927648.1
- ProteinModelPortal:   A1S6H2
- SMR:   A1S6H2
- STRING:   A1S6H2
- GeneID:   4604023
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1773
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- PhylomeDB:   A1S6H2
- ProtClustDB:   CLSK906679
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22604; Mature: 22604

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSIVVLFSAVLPFAVFADDAKELVSKLDVMQGIKANFSQKVTDQNGKLIQEGSGVIAM
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEECCCCEEEE
HQPDAFYWHLTAPDESLIVAKDNSVWVYNPFAEEVSILDMEDILKASPMALLVHRDEKRW
ECCCEEEEEEECCCCEEEEEECCCEEEECCHHHCEEEECHHHHHCCCCEEEEEECCCCCC
NEYQIDRKGSCFDITPRQGVESAVDTVSVCFANNTLSDIRLTDAQGSTSHFSLSEQAAVT
CCEEECCCCCEEECCCHHHHHHHHHHEEEEEECCCCCCEEEECCCCCCCEEECCCCCCCC
DADESLFQFQIPDGVSIDDQRRQ
CCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKKSIVVLFSAVLPFAVFADDAKELVSKLDVMQGIKANFSQKVTDQNGKLIQEGSGVIAM
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEECCCCEEEE
HQPDAFYWHLTAPDESLIVAKDNSVWVYNPFAEEVSILDMEDILKASPMALLVHRDEKRW
ECCCEEEEEEECCCCEEEEEECCCEEEECCHHHCEEEECHHHHHCCCCEEEEEECCCCCC
NEYQIDRKGSCFDITPRQGVESAVDTVSVCFANNTLSDIRLTDAQGSTSHFSLSEQAAVT
CCEEECCCCCEEECCCHHHHHHHHHHEEEEEECCCCCCEEEECCCCCCCEEECCCCCCCC
DADESLFQFQIPDGVSIDDQRRQ
CCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA