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The map label for this gene is aspC [H]

Identifier: 119774868

GI number: 119774868

Start: 2122290

End: 2123480

Strand: Reverse

Name: aspC [H]

Synonym: Sama_1733

Alternate gene names: 119774868

Gene position: 2123480-2122290 (Counterclockwise)

Preceding gene: 119774879

Following gene: 119774865

Centisome position: 49.31

GC content: 54.66

Gene sequence:

>1191_bases
ATGTTTGAGCATCTTTCGGCGTTGCCTGCCGATCCTATCCTGGGTCTTTTAACCAAATACCGTGAAGACAGCCACCCACA
CAAAGTCGACCTGGGCGTGGGTGTGTATAAAGATCCCGCCGGAAACACGCCTATTCTGAATTGTGTGAAGACCGCCGAGA
CGCTGCGCACTTCCACTGAAACCACCAAGGTCTATATCGGTCCTACCGGTTCAGCGCCCTTTAACGAATTGATGAACGAG
CTGGCTTTCGGTGCAGATCATGCCGTGGTTCAGGCACGCCGCATTCGCACAGTATCGACCCCTGGCGGAACCGGCGCCCT
GCGCGTAGCCGCTGAATTCATCGCCAAATGTAAACCCGGCGCCACCATTTGGGTGAGTGACCCCACCTGGGCAAACCACA
CAGGGCTGTTTCAGGCCGCAGGCTTAACGGTCAAAACCTATCCCTACTACGATTACGACAACAAGTGCCTGAAATTTAAT
GAAATGCTTGCGGCGCTTAAGCAAGTTGGCGCCGAAGACGCTGTACTGCTGCACGCCTGCTGCCATAACCCATCCGGTCA
GGACTTAAGTACCGCCCAGTGGGATGCCGTGGTCGAGGTTGCCAAAGACAAAGGCTTCCTGCCCTTTATCGACATGGCTT
ATCAGGGCTTTGGTGATGGCGTGGATGAAGATGCCTACGGGGTGCGCGCCATGGCAGCTGCTGTCGATAACATGGTGCTC
GCCTCTTCCTGCTCGAAGAACTTTGGTCTATACCGCGAGCGCATCGGTGCCTGCTCCATCATAGGTAAAGACAGTGCCCA
GGCAGATGTGTCGCTGTCGGTACTGCTGTATGTGGTGCGCTGCATCTACTCAATGCCACCGGCCCACGGCGCCGCCATTG
TGGAAACCATTCTGGGCTCAAACGAGCTCAAGGCCCAATGGCTGGATGAGCTTAAAGTGATGCGCGATCGCATCAACGGC
AACCGCGCCATGCTGGTAGATAAACTGCACGCACTTGGCACCAACCGCGACTTTTCCTTTATCGCCCGCCAAAAAGGCAT
GTTCTCCTTCCTTGGCATCAGTGAGGCTCAGGTAAACACCCTGATGAAGGACTACAGCATTTACATGGTGGGCTCTAGCC
GCATAAGCATTGCCGGTATAAGCGAAGAAAACGTGGATTATCTGGCCAAATCCATTATCGCCGTGCTTTAA

Upstream 100 bases:

>100_bases
GCATCCGGCTTGGCATCAACCAGGCTACAGCGATCCCGAGCAAGCTGTTACACCTTATCCCTGCGGCTTTACCAACAACG
ATTACAAGGTAGATGGAATT

Downstream 100 bases:

>100_bases
CCAACAAAGAGCTCGATAACAAAAAGGACTGCCGAGGCAGTCCTTTTTTATTCGCGATTAAAACTGATTAGCTGCTGTGC
TTGGCAGCAAATGAGCGCAT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFEHLSALPADPILGLLTKYREDSHPHKVDLGVGVYKDPAGNTPILNCVKTAETLRTSTETTKVYIGPTGSAPFNELMNE
LAFGADHAVVQARRIRTVSTPGGTGALRVAAEFIAKCKPGATIWVSDPTWANHTGLFQAAGLTVKTYPYYDYDNKCLKFN
EMLAALKQVGAEDAVLLHACCHNPSGQDLSTAQWDAVVEVAKDKGFLPFIDMAYQGFGDGVDEDAYGVRAMAAAVDNMVL
ASSCSKNFGLYRERIGACSIIGKDSAQADVSLSVLLYVVRCIYSMPPAHGAAIVETILGSNELKAQWLDELKVMRDRING
NRAMLVDKLHALGTNRDFSFIARQKGMFSFLGISEAQVNTLMKDYSIYMVGSSRISIAGISEENVDYLAKSIIAVL

Sequences:

>Translated_396_residues
MFEHLSALPADPILGLLTKYREDSHPHKVDLGVGVYKDPAGNTPILNCVKTAETLRTSTETTKVYIGPTGSAPFNELMNE
LAFGADHAVVQARRIRTVSTPGGTGALRVAAEFIAKCKPGATIWVSDPTWANHTGLFQAAGLTVKTYPYYDYDNKCLKFN
EMLAALKQVGAEDAVLLHACCHNPSGQDLSTAQWDAVVEVAKDKGFLPFIDMAYQGFGDGVDEDAYGVRAMAAAVDNMVL
ASSCSKNFGLYRERIGACSIIGKDSAQADVSLSVLLYVVRCIYSMPPAHGAAIVETILGSNELKAQWLDELKVMRDRING
NRAMLVDKLHALGTNRDFSFIARQKGMFSFLGISEAQVNTLMKDYSIYMVGSSRISIAGISEENVDYLAKSIIAVL
>Mature_396_residues
MFEHLSALPADPILGLLTKYREDSHPHKVDLGVGVYKDPAGNTPILNCVKTAETLRTSTETTKVYIGPTGSAPFNELMNE
LAFGADHAVVQARRIRTVSTPGGTGALRVAAEFIAKCKPGATIWVSDPTWANHTGLFQAAGLTVKTYPYYDYDNKCLKFN
EMLAALKQVGAEDAVLLHACCHNPSGQDLSTAQWDAVVEVAKDKGFLPFIDMAYQGFGDGVDEDAYGVRAMAAAVDNMVL
ASSCSKNFGLYRERIGACSIIGKDSAQADVSLSVLLYVVRCIYSMPPAHGAAIVETILGSNELKAQWLDELKVMRDRING
NRAMLVDKLHALGTNRDFSFIARQKGMFSFLGISEAQVNTLMKDYSIYMVGSSRISIAGISEENVDYLAKSIIAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=397, Percent_Identity=39.7984886649874, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=37.4045801526718, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI117414139, Length=385, Percent_Identity=25.7142857142857, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.7272727272727, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=42.0654911838791, Blast_Score=343, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI71981858, Length=392, Percent_Identity=40.3061224489796, Blast_Score=316, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40.7594936708861, Blast_Score=308, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17569539, Length=394, Percent_Identity=35.5329949238579, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=29.4573643410853, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=37.4407582938389, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=31.1787072243346, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.0493827160494, Blast_Score=265, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6322743, Length=427, Percent_Identity=33.0210772833724, Blast_Score=218, Evalue=9e-58,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.8989898989899, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=39.8989898989899, Blast_Score=301, Evalue=6e-82,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=40.3598971722365, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24654046, Length=391, Percent_Identity=37.8516624040921, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI19922362, Length=391, Percent_Identity=37.8516624040921, Blast_Score=276, Evalue=2e-74,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42923; Mature: 42923

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEHLSALPADPILGLLTKYREDSHPHKVDLGVGVYKDPAGNTPILNCVKTAETLRTSTE
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCC
TTKVYIGPTGSAPFNELMNELAFGADHAVVQARRIRTVSTPGGTGALRVAAEFIAKCKPG
CEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCC
ATIWVSDPTWANHTGLFQAAGLTVKTYPYYDYDNKCLKFNEMLAALKQVGAEDAVLLHAC
CEEEECCCCCCCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHH
CHNPSGQDLSTAQWDAVVEVAKDKGFLPFIDMAYQGFGDGVDEDAYGVRAMAAAVDNMVL
HCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ASSCSKNFGLYRERIGACSIIGKDSAQADVSLSVLLYVVRCIYSMPPAHGAAIVETILGS
HHHCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
NELKAQWLDELKVMRDRINGNRAMLVDKLHALGTNRDFSFIARQKGMFSFLGISEAQVNT
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHH
LMKDYSIYMVGSSRISIAGISEENVDYLAKSIIAVL
HHHCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MFEHLSALPADPILGLLTKYREDSHPHKVDLGVGVYKDPAGNTPILNCVKTAETLRTSTE
CCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCC
TTKVYIGPTGSAPFNELMNELAFGADHAVVQARRIRTVSTPGGTGALRVAAEFIAKCKPG
CEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCC
ATIWVSDPTWANHTGLFQAAGLTVKTYPYYDYDNKCLKFNEMLAALKQVGAEDAVLLHAC
CEEEECCCCCCCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHH
CHNPSGQDLSTAQWDAVVEVAKDKGFLPFIDMAYQGFGDGVDEDAYGVRAMAAAVDNMVL
HCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ASSCSKNFGLYRERIGACSIIGKDSAQADVSLSVLLYVVRCIYSMPPAHGAAIVETILGS
HHHCCCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
NELKAQWLDELKVMRDRINGNRAMLVDKLHALGTNRDFSFIARQKGMFSFLGISEAQVNT
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHH
LMKDYSIYMVGSSRISIAGISEENVDYLAKSIIAVL
HHHCCEEEEEECCEEEEEECCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]