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The map label for this gene is fadH [H]

Identifier: 119774859

GI number: 119774859

Start: 2109514

End: 2111529

Strand: Direct

Name: fadH [H]

Synonym: Sama_1724

Alternate gene names: 119774859

Gene position: 2109514-2111529 (Clockwise)

Preceding gene: 119774856

Following gene: 119774860

Centisome position: 48.99

GC content: 53.08

Gene sequence:

>2016_bases
ATGTCGTTTCCGCACTTGTTGAAGCCATTGGATTTAGGCTTTACCCAGCTTAAAAACCGCGTACTCATGGGCTCTATGCA
CACAGGGCTAGAAGAAGAAAAGGGCGGCTTTGAAAAGCTGGCTGCATTTTATCGGGAGCGTGCTGCCGGTGGCGTAGGTC
TGATAGTGACCGGGGGTATTTCCCCTAATTTACGTGGCAGATTAGCGCCCCATGCCTCTCAGCTGAGTTTTCCCTGGCAG
GTGAAACGCCACCGTATTGTCACTGACGCTGTGCATGGCGCAGGTGGCAAAATCTGTATGCAAATTTTGCATGCGGGCCG
CTACGGTTATCATCCGTTTTCCCTGGCACCCAGTGCGCTTAAAGCCCCCATTACGCCTTTTAAGCCCAGTGCCATGTCGG
CTCGGCAAATTCGCAGCACCATCAAGGATTACGCCACCAGTGCCAAACTGGCACGTAAGGCAGGCTACGATGGTGTGGAA
GTCATGGGCTCTGAAGGCTATCTCATCAATCAGTTTATCTGCTCACGCACCAATAAACGTCAGGATGAATGGGGCGGCAG
TTTTGAAAACCGCAGCCGTTTCCCGTTGGAGATAGTGCGTGCCATTCGCGCTGCGGTAGGATCTGATTTTATTATTATCT
TTCGCCTCTCGATGCTGGATTTGGTGGAAGAAGGCTCCAGCTGGGATGAAGTGGTGGCACTAGCCAAAGGGCTCGAAGAA
GCGGGCGTTACCATTATTAATACCGGCATTGGCTGGCATGAAGCCCGGATCCCAACCATTGCCACCAGTGTGCCCAGAGG
CGCCTTTGCCTGGGTGACTGAGCGTTTGAAGCAGGAAGTGCACATTCCACTCATTGCGACCAACAGGATTAATACGCCGG
AAATTGCTGAGCAAATTCTCGCATCCGGTCAGGCTGATATGGTGTCAATGGCAAGACCATTCCTGGCCGACCCTGACTTT
GTCAATAAAGCGGCCGCAGGGCAGAGTGAGCTGATTAATACCTGTATTGGCTGTAATCAGGCGTGTCTAGACCATACCTT
CAAGATGAAGCGCGCAACCTGTTTGGTTAACCCAAGGGCCTGTTACGAAACCGAGATTAACTTCCCCAAAACCTCGCAGC
CCAAAAAGATAGCCGTGATGGGGGCAGGGCCGGCGGGAATGGCGTTTTCCATATACGCAGCCAGCCGCGGCCATAATGTG
GTGTTGTTTGAAGCCAAAGGGGAAGTGGGGGGCCAATTCAACCTTGCCCGTAAAATTCCCGGTAAGGAAGAGTTTGACGA
AACCATCCGCTATTTCAATAACCAGATGCGGCAAACCGGGGTTGAGCTAAGGCTTAACACCCGTCTCGATGCCTCAGTGC
TTAATGATGAAGATTTTGATGAGGTAGTTATCGCCGCGGGTGTGGTTCCCCGTGCAGTAAAACTGCCGGGCTTCGATTCG
CCCCGGGTGGTCAATTATCAACAGGTGCTGAATGGTGAAGTAAGGGTAGGACAGAAAGTGGCCTTGATTGGGGCCGGAGG
TATTGGCTTTGATATGGCACATTACCTGGGTGAAAAAGACTCAACTACGCTCGATCCCAAACGTTGGCGTGACCAATGGG
GCATAGACGATGCCTACGAAGCCCGCGGCGGCCTCAAGGCGCCAATAAAAGAACCGGCCGAGCGCACCATTTACCTGCTT
CAGCGTAAAACCACGCCCATGGGCAAGGGACTTGGGAAGACCACGGGCTGGATCCACCGCACCGTGGCCAAGATGCATGG
GGTTGTTCAGATGAACGGCGTCAGTTATGAGTCCTTCGATGAGCAAGGGTTACATATTCGTGTGAATGAAGAGACCAAGG
TACTCGATGTGAATACAGTCATACTCTGCGCCGGTCAGGAATCCAATCGGTCTCTGGTGGCCGAAATGGAAGCCACAGGT
AAGCCTGTTCATTTGATTGGTGGTGTGGATGTAGCGGCAGAGCTCGATGCCAAACGGGCCATTCGCCAGGGCGCAGAGCT
CGCGATGCGCATCTAA

Upstream 100 bases:

>100_bases
CAATTGTAAAGGTTTTTAACATTCAGTGGGCTGGACGGTTGAGCTTATACTCGACACAGGATATGCTGACTTGGATCACA
TGTTTTAAAAGGGTGTTTGA

Downstream 100 bases:

>100_bases
ACCTAATCGACGTGGTAAATTGCCCCGACAGCTTTTGACGTGGGTTAATTGTTACTCACCGGTCATCAATATACATACAC
TTGATATTTAAACCTTGAAA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSFPHLLKPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYRERAAGGVGLIVTGGISPNLRGRLAPHASQLSFPWQ
VKRHRIVTDAVHGAGGKICMQILHAGRYGYHPFSLAPSALKAPITPFKPSAMSARQIRSTIKDYATSAKLARKAGYDGVE
VMGSEGYLINQFICSRTNKRQDEWGGSFENRSRFPLEIVRAIRAAVGSDFIIIFRLSMLDLVEEGSSWDEVVALAKGLEE
AGVTIINTGIGWHEARIPTIATSVPRGAFAWVTERLKQEVHIPLIATNRINTPEIAEQILASGQADMVSMARPFLADPDF
VNKAAAGQSELINTCIGCNQACLDHTFKMKRATCLVNPRACYETEINFPKTSQPKKIAVMGAGPAGMAFSIYAASRGHNV
VLFEAKGEVGGQFNLARKIPGKEEFDETIRYFNNQMRQTGVELRLNTRLDASVLNDEDFDEVVIAAGVVPRAVKLPGFDS
PRVVNYQQVLNGEVRVGQKVALIGAGGIGFDMAHYLGEKDSTTLDPKRWRDQWGIDDAYEARGGLKAPIKEPAERTIYLL
QRKTTPMGKGLGKTTGWIHRTVAKMHGVVQMNGVSYESFDEQGLHIRVNEETKVLDVNTVILCAGQESNRSLVAEMEATG
KPVHLIGGVDVAAELDAKRAIRQGAELAMRI

Sequences:

>Translated_671_residues
MSFPHLLKPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYRERAAGGVGLIVTGGISPNLRGRLAPHASQLSFPWQ
VKRHRIVTDAVHGAGGKICMQILHAGRYGYHPFSLAPSALKAPITPFKPSAMSARQIRSTIKDYATSAKLARKAGYDGVE
VMGSEGYLINQFICSRTNKRQDEWGGSFENRSRFPLEIVRAIRAAVGSDFIIIFRLSMLDLVEEGSSWDEVVALAKGLEE
AGVTIINTGIGWHEARIPTIATSVPRGAFAWVTERLKQEVHIPLIATNRINTPEIAEQILASGQADMVSMARPFLADPDF
VNKAAAGQSELINTCIGCNQACLDHTFKMKRATCLVNPRACYETEINFPKTSQPKKIAVMGAGPAGMAFSIYAASRGHNV
VLFEAKGEVGGQFNLARKIPGKEEFDETIRYFNNQMRQTGVELRLNTRLDASVLNDEDFDEVVIAAGVVPRAVKLPGFDS
PRVVNYQQVLNGEVRVGQKVALIGAGGIGFDMAHYLGEKDSTTLDPKRWRDQWGIDDAYEARGGLKAPIKEPAERTIYLL
QRKTTPMGKGLGKTTGWIHRTVAKMHGVVQMNGVSYESFDEQGLHIRVNEETKVLDVNTVILCAGQESNRSLVAEMEATG
KPVHLIGGVDVAAELDAKRAIRQGAELAMRI
>Mature_670_residues
SFPHLLKPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYRERAAGGVGLIVTGGISPNLRGRLAPHASQLSFPWQV
KRHRIVTDAVHGAGGKICMQILHAGRYGYHPFSLAPSALKAPITPFKPSAMSARQIRSTIKDYATSAKLARKAGYDGVEV
MGSEGYLINQFICSRTNKRQDEWGGSFENRSRFPLEIVRAIRAAVGSDFIIIFRLSMLDLVEEGSSWDEVVALAKGLEEA
GVTIINTGIGWHEARIPTIATSVPRGAFAWVTERLKQEVHIPLIATNRINTPEIAEQILASGQADMVSMARPFLADPDFV
NKAAAGQSELINTCIGCNQACLDHTFKMKRATCLVNPRACYETEINFPKTSQPKKIAVMGAGPAGMAFSIYAASRGHNVV
LFEAKGEVGGQFNLARKIPGKEEFDETIRYFNNQMRQTGVELRLNTRLDASVLNDEDFDEVVIAAGVVPRAVKLPGFDSP
RVVNYQQVLNGEVRVGQKVALIGAGGIGFDMAHYLGEKDSTTLDPKRWRDQWGIDDAYEARGGLKAPIKEPAERTIYLLQ
RKTTPMGKGLGKTTGWIHRTVAKMHGVVQMNGVSYESFDEQGLHIRVNEETKVLDVNTVILCAGQESNRSLVAEMEATGK
PVHLIGGVDVAAELDAKRAIRQGAELAMRI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=674, Percent_Identity=57.2700296735905, Blast_Score=785, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=346, Percent_Identity=28.9017341040462, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=253, Percent_Identity=27.6679841897233, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=326, Percent_Identity=24.5398773006135, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17559804, Length=250, Percent_Identity=27.2, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=251, Percent_Identity=27.0916334661355, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI72001454, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=314, Percent_Identity=25.4777070063694, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=224, Percent_Identity=27.6785714285714, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=227, Percent_Identity=30.8370044052863, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=233, Percent_Identity=28.3261802575107, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73421; Mature: 73290

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPHLLKPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYRERAAGGVGLIVTGGI
CCCCHHCCHHHCCHHHHHCCEEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPHASQLSFPWQVKRHRIVTDAVHGAGGKICMQILHAGRYGYHPFSLAPSAL
CCCCCCCCCCCHHHCCCCHHHHHHEEEHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCHHH
KAPITPFKPSAMSARQIRSTIKDYATSAKLARKAGYDGVEVMGSEGYLINQFICSRTNKR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCC
QDEWGGSFENRSRFPLEIVRAIRAAVGSDFIIIFRLSMLDLVEEGSSWDEVVALAKGLEE
CHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARIPTIATSVPRGAFAWVTERLKQEVHIPLIATNRINTPEIAEQIL
CCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
ASGQADMVSMARPFLADPDFVNKAAAGQSELINTCIGCNQACLDHTFKMKRATCLVNPRA
HCCCHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCH
CYETEINFPKTSQPKKIAVMGAGPAGMAFSIYAASRGHNVVLFEAKGEVGGQFNLARKIP
HEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEHCCCC
GKEEFDETIRYFNNQMRQTGVELRLNTRLDASVLNDEDFDEVVIAAGVVPRAVKLPGFDS
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHCCCCCEEECCCCCC
PRVVNYQQVLNGEVRVGQKVALIGAGGIGFDMAHYLGEKDSTTLDPKRWRDQWGIDDAYE
CCEECHHHHHCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHH
ARGGLKAPIKEPAERTIYLLQRKTTPMGKGLGKTTGWIHRTVAKMHGVVQMNGVSYESFD
HCCCCCCCCCCHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCC
EQGLHIRVNEETKVLDVNTVILCAGQESNRSLVAEMEATGKPVHLIGGVDVAAELDAKRA
CCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEHHCCCCCEEEEECCCHHHHHHHHHH
IRQGAELAMRI
HHCCHHHEECC
>Mature Secondary Structure 
SFPHLLKPLDLGFTQLKNRVLMGSMHTGLEEEKGGFEKLAAFYRERAAGGVGLIVTGGI
CCCHHCCHHHCCHHHHHCCEEECHHHCCCCHHCCCHHHHHHHHHHHCCCCEEEEEECCC
SPNLRGRLAPHASQLSFPWQVKRHRIVTDAVHGAGGKICMQILHAGRYGYHPFSLAPSAL
CCCCCCCCCCCHHHCCCCHHHHHHEEEHHHHCCCCHHHHHHHHHCCCCCCCCHHCCCHHH
KAPITPFKPSAMSARQIRSTIKDYATSAKLARKAGYDGVEVMGSEGYLINQFICSRTNKR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHCCCCCC
QDEWGGSFENRSRFPLEIVRAIRAAVGSDFIIIFRLSMLDLVEEGSSWDEVVALAKGLEE
CHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
AGVTIINTGIGWHEARIPTIATSVPRGAFAWVTERLKQEVHIPLIATNRINTPEIAEQIL
CCCEEEECCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHH
ASGQADMVSMARPFLADPDFVNKAAAGQSELINTCIGCNQACLDHTFKMKRATCLVNPRA
HCCCHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCH
CYETEINFPKTSQPKKIAVMGAGPAGMAFSIYAASRGHNVVLFEAKGEVGGQFNLARKIP
HEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEEHCCCC
GKEEFDETIRYFNNQMRQTGVELRLNTRLDASVLNDEDFDEVVIAAGVVPRAVKLPGFDS
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCHHHHHHHHCCCCCEEECCCCCC
PRVVNYQQVLNGEVRVGQKVALIGAGGIGFDMAHYLGEKDSTTLDPKRWRDQWGIDDAYE
CCEECHHHHHCCCEECCCEEEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHH
ARGGLKAPIKEPAERTIYLLQRKTTPMGKGLGKTTGWIHRTVAKMHGVVQMNGVSYESFD
HCCCCCCCCCCHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCC
EQGLHIRVNEETKVLDVNTVILCAGQESNRSLVAEMEATGKPVHLIGGVDVAAELDAKRA
CCCCEEEECCCCEEEEEEEEEEEECCCCCCCEEEEHHCCCCCEEEEECCCHHHHHHHHHH
IRQGAELAMRI
HHCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]