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The map label for this gene is pfeR [H]

Identifier: 119774853

GI number: 119774853

Start: 2103739

End: 2104413

Strand: Direct

Name: pfeR [H]

Synonym: Sama_1718

Alternate gene names: 119774853

Gene position: 2103739-2104413 (Clockwise)

Preceding gene: 119774852

Following gene: 119774854

Centisome position: 48.85

GC content: 48.74

Gene sequence:

>675_bases
GTGAATAAAATACTCTTGGTCGAAGACGACAATGGATTTCGGGAGCTGCTAACCGAGGCTCTCGAGCGGGAAGGTTTGTG
TGTATCTGTTGCCACCGATGGCTTTGAAGCCCTTACTTTGATGGAAAAGGATACGCCAGAACTTATTCTTCTGGATCTGA
TGATGCCGGGAATGGACGGATTTTCCATGTTAATGCAACGGAGAAACCAGTTACCCGTGATTGTGATATCCGCACTCGAC
AGCGAAGAAGAGCGAATTCGTGGATATCAGTTGGGCGCCGATGATTTTTTGACCAAGCCATTCAGCATCAAAGAGTTAAT
CGTACGCATCCAGGCGCTGGCCCGAAGGCTGAAACGCCAGGATGTACCGACACACAAAGAAGCAGACACCCACATTCACT
TTGATGAAACACGCTACACAATCGGTATTGGCGACCGGCAAGTCATGCTTACCCAAACCGAGTTTAAATTGTTTCGCTAC
TTGTTTGAACGAAAGGGGCAGGTCGTGACCAAGGCCGAACTGCAACGTAGTGTGCTGCAGAAAGAGTTTGGCCGTTTTGA
CCGTAACCTTGATATGCATATCAGTAATACCCGCCGTAAGCTTGCACAAACCAAGTTGCCGCGCAGCATGATAAATACGG
TTCGTGGTCAGGGGTACAGCTTCGCCTGTTGTTAG

Upstream 100 bases:

>100_bases
ACATTCAGAACCAAGGTCACATAACAGTGGCAAATCTACTTGGCTGAGGCTTAATATCATGCTAATGTGAATAACAACCG
TTCGCATTTAGATTTGAATC

Downstream 100 bases:

>100_bases
TAAGAATTGGCCGCAACGCATTCAAGAACGGTTGCTTTTAGGGTATTCTAGGGCATCTTTCAGGCTCGGTATCGCCGGGC
ATGTATCCTACACACAGAGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNKILLVEDDNGFRELLTEALEREGLCVSVATDGFEALTLMEKDTPELILLDLMMPGMDGFSMLMQRRNQLPVIVISALD
SEEERIRGYQLGADDFLTKPFSIKELIVRIQALARRLKRQDVPTHKEADTHIHFDETRYTIGIGDRQVMLTQTEFKLFRY
LFERKGQVVTKAELQRSVLQKEFGRFDRNLDMHISNTRRKLAQTKLPRSMINTVRGQGYSFACC

Sequences:

>Translated_224_residues
MNKILLVEDDNGFRELLTEALEREGLCVSVATDGFEALTLMEKDTPELILLDLMMPGMDGFSMLMQRRNQLPVIVISALD
SEEERIRGYQLGADDFLTKPFSIKELIVRIQALARRLKRQDVPTHKEADTHIHFDETRYTIGIGDRQVMLTQTEFKLFRY
LFERKGQVVTKAELQRSVLQKEFGRFDRNLDMHISNTRRKLAQTKLPRSMINTVRGQGYSFACC
>Mature_224_residues
MNKILLVEDDNGFRELLTEALEREGLCVSVATDGFEALTLMEKDTPELILLDLMMPGMDGFSMLMQRRNQLPVIVISALD
SEEERIRGYQLGADDFLTKPFSIKELIVRIQALARRLKRQDVPTHKEADTHIHFDETRYTIGIGDRQVMLTQTEFKLFRY
LFERKGQVVTKAELQRSVLQKEFGRFDRNLDMHISNTRRKLAQTKLPRSMINTVRGQGYSFACC

Specific function: Member of the two-component regulatory system pfeR/pfeS. Activates expression of the ferric enterobactin receptor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=41.4529914529915, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=33.0357142857143, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=133, Evalue=7e-33,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=31.858407079646, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.070796460177, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=31.8777292576419, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.0810810810811, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=31.2217194570136, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.1310043668122, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.3478260869565, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=31.2775330396476, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=28.2511210762332, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=26.890756302521, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=26.8398268398268, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.9593495934959, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787487, Length=107, Percent_Identity=39.2523364485981, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=33.8842975206612, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=135, Percent_Identity=31.8518518518519, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25934; Mature: 25934

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKILLVEDDNGFRELLTEALEREGLCVSVATDGFEALTLMEKDTPELILLDLMMPGMDG
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEHHCCCCCH
FSMLMQRRNQLPVIVISALDSEEERIRGYQLGADDFLTKPFSIKELIVRIQALARRLKRQ
HHHHHHHCCCCCEEEEEECCCHHHHHCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHC
DVPTHKEADTHIHFDETRYTIGIGDRQVMLTQTEFKLFRYLFERKGQVVTKAELQRSVLQ
CCCCCCCCCCEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
KEFGRFDRNLDMHISNTRRKLAQTKLPRSMINTVRGQGYSFACC
HHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MNKILLVEDDNGFRELLTEALEREGLCVSVATDGFEALTLMEKDTPELILLDLMMPGMDG
CCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEEHHCCCCCH
FSMLMQRRNQLPVIVISALDSEEERIRGYQLGADDFLTKPFSIKELIVRIQALARRLKRQ
HHHHHHHCCCCCEEEEEECCCHHHHHCCEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHC
DVPTHKEADTHIHFDETRYTIGIGDRQVMLTQTEFKLFRYLFERKGQVVTKAELQRSVLQ
CCCCCCCCCCEEEECCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHH
KEFGRFDRNLDMHISNTRRKLAQTKLPRSMINTVRGQGYSFACC
HHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8361354; 10984043 [H]