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The map label for this gene is fldA [H]

Identifier: 119774837

GI number: 119774837

Start: 2082200

End: 2082727

Strand: Reverse

Name: fldA [H]

Synonym: Sama_1701

Alternate gene names: 119774837

Gene position: 2082727-2082200 (Counterclockwise)

Preceding gene: 119774838

Following gene: 119774836

Centisome position: 48.37

GC content: 51.89

Gene sequence:

>528_bases
ATGGCTACTGTAGGTCTTTTTTTCGGCAGTGACACAGGCAACACCGAAGCTGTCGCCAAGATGATCCAGAAAAAACTGGG
TAAGCAGATGGTGGATGTCAAAGACATCGCCAAGAGCACCAAGGAGCAGATCGCCGACTTTGACCTGCTGCTGTTCGGGA
TCCCAACCTGGTACTACGGTGAAGCGCAGTGCGATTGGGACGACTTTTTCCCTGAGCTTGAGCAAATCGACTTTACCGAC
AAGCTGGTAGCCATTTTCGGTTGCGGCGATCAGGAAGATTATGCCGAATACTTCCTCGATGCCATGGGCATGGTACGTGA
CATCGTCGAAACCCGTGGTGGCATTATCGTTGGTCACTGGCCTACTGCCGGTTATAACTTCGAAGCCTCCAAAGCGCTGG
TCGATGACGACCACTTTGTGGGTCTGGGTATTGATGAAGACCGTCAGCCCGAACTCACCGAAGAGCGCGTTGATCAGTGG
GTAAAACAGATTTACGAAGAAATGTGTCTGGCCGAGTTGGCAGACTGA

Upstream 100 bases:

>100_bases
GCAGCCAATTAATCGAATGCATACTTAAGCAATCGTTTGACGATTGAGTCAAACTTTTGTGGATGCCGCGTAAACGCAAC
TGATATTTAAAGGAAAGACA

Downstream 100 bases:

>100_bases
TTTCTTGAAGTTTGAAAAGGCGGCGTTTACGCCGCTTTTTTCATTTCCGCGCCAACCGAATTCGGGTCTCAAGCGTCTAT
GACCAGTCCTAAATCCAGCC

Product: flavodoxin FldA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MATVGLFFGSDTGNTEAVAKMIQKKLGKQMVDVKDIAKSTKEQIADFDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTD
KLVAIFGCGDQEDYAEYFLDAMGMVRDIVETRGGIIVGHWPTAGYNFEASKALVDDDHFVGLGIDEDRQPELTEERVDQW
VKQIYEEMCLAELAD

Sequences:

>Translated_175_residues
MATVGLFFGSDTGNTEAVAKMIQKKLGKQMVDVKDIAKSTKEQIADFDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTD
KLVAIFGCGDQEDYAEYFLDAMGMVRDIVETRGGIIVGHWPTAGYNFEASKALVDDDHFVGLGIDEDRQPELTEERVDQW
VKQIYEEMCLAELAD
>Mature_174_residues
ATVGLFFGSDTGNTEAVAKMIQKKLGKQMVDVKDIAKSTKEQIADFDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTDK
LVAIFGCGDQEDYAEYFLDAMGMVRDIVETRGGIIVGHWPTAGYNFEASKALVDDDHFVGLGIDEDRQPELTEERVDQWV
KQIYEEMCLAELAD

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=173, Percent_Identity=75.1445086705202, Blast_Score=280, Evalue=3e-77,
Organism=Escherichia coli, GI1789262, Length=168, Percent_Identity=40.4761904761905, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 19818; Mature: 19687

Theoretical pI: Translated: 3.88; Mature: 3.88

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVGLFFGSDTGNTEAVAKMIQKKLGKQMVDVKDIAKSTKEQIADFDLLLFGIPTWYYG
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
EAQCDWDDFFPELEQIDFTDKLVAIFGCGDQEDYAEYFLDAMGMVRDIVETRGGIIVGHW
CCCCCHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
PTAGYNFEASKALVDDDHFVGLGIDEDRQPELTEERVDQWVKQIYEEMCLAELAD
CCCCCCCCCCCEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATVGLFFGSDTGNTEAVAKMIQKKLGKQMVDVKDIAKSTKEQIADFDLLLFGIPTWYYG
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
EAQCDWDDFFPELEQIDFTDKLVAIFGCGDQEDYAEYFLDAMGMVRDIVETRGGIIVGHW
CCCCCHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
PTAGYNFEASKALVDDDHFVGLGIDEDRQPELTEERVDQWVKQIYEEMCLAELAD
CCCCCCCCCCCEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]