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The map label for this gene is asnC

Identifier: 119774820

GI number: 119774820

Start: 2058084

End: 2059484

Strand: Reverse

Name: asnC

Synonym: Sama_1684

Alternate gene names: 119774820

Gene position: 2059484-2058084 (Counterclockwise)

Preceding gene: 119774822

Following gene: 119774815

Centisome position: 47.83

GC content: 55.32

Gene sequence:

>1401_bases
ATGAGCATTGCATCTATCGCATCCGTATTTAAGGGTGATTTCGCCCCCGGTACCGAGATCACGGTACGCGGTTGGGTTCG
TACCCGTCGGGATTCCAAGGCAGGGATCTCCTTCCTCGCCGTCTATGACGGCTCCTGTTTCGATGCCATTCAGGGCGTAG
TGCCCAATGCTCTGTCCAATTATAATGACGAAGTGCTGAAGCTGACCGCTGGCTGCTCTGTGGAAATGACCGGTAATCTG
GTGGAGTCTCCCGGCTCAGGCCAGGCATTCGAACTTCAGGCCACTGCCGTGAAAGTGACCGGCTGGGTAGACGATCCGGA
CACTTACCCCATGGCTGCCAAGCGCCACTCAATCGAGCACCTGCGCGACGTGGCTCACCTGCGTCCACGTACCAACATCA
TTGGTGCCGTGGCCCGTGTGCGTAACTGTCTGTCTCAGGCCATTCACCGCTTCTACCACGAGAATGGTTTTATTTGGGTA
TCCACTCCCATCATCACCGCCTCCGACTGTGAAGGCGCCGGTGAGATGTTCCGCGTCTCCACTCTGGACATGGAAAACCT
GCCACGTACCGACGCTGGCAAAGTAGATTACGACCAGGACTTTTTCGGTAAAGAAGCCTTCCTGACCGTATCGGGTCAGC
TGAACGGCGAAACTTACGCCTGTGCCCTGTCAAAAATCTACACCTTCGGCCCAACCTTCCGCGCCGAAAACTCCAACACC
AGCCGTCACCTGGCGGAATTCTGGATGGTGGAGCCGGAAGTGGCCTTTGCCGATCTGAACGATATCGCCGGTCTGGCGGA
ATCCATGCTCAAGTACTGCTTCAATGCCGTACTGCAAGAGCGCATGGACGATATGAAGTTCTTCGCCGAGCGTGTAGATG
GCAGTGTTATCGATCGTCTGCAAAGTTTTGTGAGCAGCGACTTTGCCCAGGTTGATTACACCGACGCCGTTGAAATCCTG
CAAAACTGCGGTAAGACCTTCGAATATCCCGTTGAGTGGGGTATCGATCTGCAGTCTGAGCACGAGCGTTATCTGGCCGA
AGAGCACTTCAAAGCCCCTGTGGTAGTGAAGAACTATCCAAAAGACATCAAAGCCTTCTACATGCGCCTCAACGAAGATG
GCAAGACAGTCGCGGCCATGGATGTACTGGCACCCGGCATCGGTGAAATCATCGGTGGCTCCCAGCGTGAAGAGCGACTG
GACGTACTGGATGCCCGCCTCGAAGAGATGAACCTGTCGAAAGAAGACTACTGGTGGTACCGTGATCTGCGCCGTTATGG
CACAGTGCCACATGCCGGTTTCGGTCTGGGCTTCGAGCGTCTGGTCTCTTACGTGACCGGTGTGGGTAACATCCGTGATG
TGATCCCATTCCCACGTGCACCACGCAGCGCTAACTTCTAA

Upstream 100 bases:

>100_bases
CGCAGCATACCTTTTTCAGCTTGAGAAAAGCCACCGGAAAGGTAATATAAACCTCCTTTTTGATTTTATATTACATGTTT
CGTTGGAGATAAGCGCAGCA

Downstream 100 bases:

>100_bases
TAGCGTACAAGCAATTAGCGAAAAAATGATAAAGCCGCCTTATGGGCGGCTTTTCTATTTATGTTTCCTGCTCCCCAACA
ATCACACTCAGCGCTGCACC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSIASIASVFKGDFAPGTEITVRGWVRTRRDSKAGISFLAVYDGSCFDAIQGVVPNALSNYNDEVLKLTAGCSVEMTGNL
VESPGSGQAFELQATAVKVTGWVDDPDTYPMAAKRHSIEHLRDVAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFIWV
STPIITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFADLNDIAGLAESMLKYCFNAVLQERMDDMKFFAERVDGSVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGKTFEYPVEWGIDLQSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARLEEMNLSKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVGNIRDVIPFPRAPRSANF

Sequences:

>Translated_466_residues
MSIASIASVFKGDFAPGTEITVRGWVRTRRDSKAGISFLAVYDGSCFDAIQGVVPNALSNYNDEVLKLTAGCSVEMTGNL
VESPGSGQAFELQATAVKVTGWVDDPDTYPMAAKRHSIEHLRDVAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFIWV
STPIITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFADLNDIAGLAESMLKYCFNAVLQERMDDMKFFAERVDGSVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGKTFEYPVEWGIDLQSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDARLEEMNLSKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVGNIRDVIPFPRAPRSANF
>Mature_465_residues
SIASIASVFKGDFAPGTEITVRGWVRTRRDSKAGISFLAVYDGSCFDAIQGVVPNALSNYNDEVLKLTAGCSVEMTGNLV
ESPGSGQAFELQATAVKVTGWVDDPDTYPMAAKRHSIEHLRDVAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFIWVS
TPIITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFADLNDIAGLAESMLKYCFNAVLQERMDDMKFFAERVDGSVIDRLQSFVSSDFAQVDYTDAVEILQ
NCGKTFEYPVEWGIDLQSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDARLEEMNLSKEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVGNIRDVIPFPRAPRSANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=454, Percent_Identity=44.0528634361233, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI4758762, Length=452, Percent_Identity=27.8761061946903, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI45439306, Length=351, Percent_Identity=27.9202279202279, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=79.8283261802575, Blast_Score=804, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17556372, Length=426, Percent_Identity=30.2816901408451, Blast_Score=191, Evalue=9e-49,
Organism=Caenorhabditis elegans, GI71984122, Length=453, Percent_Identity=29.1390728476821, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=481, Percent_Identity=25.1559251559252, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=470, Percent_Identity=37.6595744680851, Blast_Score=293, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=459, Percent_Identity=29.1938997821351, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6323011, Length=479, Percent_Identity=24.0083507306889, Blast_Score=109, Evalue=9e-25,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=35.9913793103448, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI19921528, Length=474, Percent_Identity=28.0590717299578, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=26.8221574344023, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_SHEAM (A1S684)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927560.1
- ProteinModelPortal:   A1S684
- SMR:   A1S684
- STRING:   A1S684
- GeneID:   4603935
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1684
- NMPDR:   fig|326297.7.peg.1592
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A1S684
- ProtClustDB:   PRK03932
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52100; Mature: 51969

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASIASVFKGDFAPGTEITVRGWVRTRRDSKAGISFLAVYDGSCFDAIQGVVPNALSN
CCHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHC
YNDEVLKLTAGCSVEMTGNLVESPGSGQAFELQATAVKVTGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCCEEECCCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRDVAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFIWVSTPIITASDCEGAGEMFRVS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFADLNDIAGLAESMLKYCFNAVLQERMDDMKFFAERVDGSVIDRL
HHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGKTFEYPVEWGIDLQSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLEEMNLSKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVGNIRDVIPFPRAPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIASIASVFKGDFAPGTEITVRGWVRTRRDSKAGISFLAVYDGSCFDAIQGVVPNALSN
CHHHHHHHHCCCCCCCCCEEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHCCHHHHC
YNDEVLKLTAGCSVEMTGNLVESPGSGQAFELQATAVKVTGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCCEEECCCEECCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHH
LRDVAHLRPRTNIIGAVARVRNCLSQAIHRFYHENGFIWVSTPIITASDCEGAGEMFRVS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDQDFFGKEAFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFADLNDIAGLAESMLKYCFNAVLQERMDDMKFFAERVDGSVIDRL
HHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGKTFEYPVEWGIDLQSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARLEEMNLSKEDYWWY
HHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVGNIRDVIPFPRAPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA