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The map label for this gene is malZ [C]

Identifier: 119774796

GI number: 119774796

Start: 2028170

End: 2030221

Strand: Reverse

Name: malZ [C]

Synonym: Sama_1660

Alternate gene names: 119774796

Gene position: 2030221-2028170 (Counterclockwise)

Preceding gene: 119774797

Following gene: 119774795

Centisome position: 47.15

GC content: 54.19

Gene sequence:

>2052_bases
ATGGAGCAACTCACATTAAGCGCGCAGGGCGCTGCCATCCACAGTCGCGTCGCCCGGCGCCTGTGCCTGACGGTGTTTAT
CGGCTTAAGTGCGGCCACATCCACTGCCGCCCTCTGTGTGCCCATGCAGGGGCACGAAAACGCCTTAAACAGCAATACAC
TCAATCCCCTCAGCCTCAGTCAGGCGCCGCATTCCGGCCATGGGGTTACGTCAAGCTCAGTGAAAGTCGAGCAAGTGAAG
GTCGAGCCCCTGAACTGGTGGGTTGGGATGGAAAACCCTCAGCTTGAATTGATGATCACAGGTGAAGGAGTCGCACACAG
TACCCTGAGGCTTGAAAATGCCCTTGGCGCAAAACTGCTGGAGATCATTCCCGGCGACAGCCCCAACTACCTGTTTGTGA
AGCTCGACCTCTCGACCGCCAGTACCGGCATCCTCACTCTGGTGCTAAGCCGCCCCGCAAGCACAATCAATCCGGCAACT
GACCTGACAATCCCATACGAGCTTAAAGCAAGAGCCCCCGGTAGCAAGGAACGTCAGGGGTACGGCAACAGGGACGTGAT
GTATCTCATCACCCCCGACCGTTTTGCCAATGGCGATAAAGCGAATGACAATCTGCCCGGTTTTGACGACAAGCCCAGTA
ACCCGGTCTACAGCGAACCTGGCAACAGTCGCGACAACGCCCGCCACGGTGGCGATCTGGCCGGTATTGAGCACAGGCTC
GATTATCTTAACGACCTTGGAGTGACCCAGCTTTGGCTAAATCCACTGCTGGAAAATCGTCAGCCGGCCTATTCCTATCA
TGGCTACGCCATCACAGATTTTTATCAAATCGATGCCCGCTTCGGCAGCAATGCGCAATATCAGGCATTGGTCAGAAAAG
CAGCCGATAGAGGCCTTGGCGTCATCATGGATGTAGTACTCAATCACATGGGTTCGGGACATCCCTGGATGCAGGATCTG
CCGTTTAATGACTGGGTCAATCCCCGGTCAATGCACACCAGCCACAGACGCACGGCGGTTCAGGACCCTTACGCCGCGCC
CAAAGATGCGGCCGCCTTTACCGACGGCTGGTTTGTGGACAGCATGCCGGACCTCAATCAGCGTAATCCCCACCTTGCCA
CTTACCTGATTCAAAATAACCTTTGGTGGATTGAATACGCGGGGCTGTCGGGTCTGAGAATCGACACCTGGTCTTACTCA
GATAAGCACTTCCTCAAGGCGTTTTCCGAGGCCATCATGGCGGAATATCCCCATTTCAACATGGTGGGGGAAGAATGGAG
CGGCAATCCTGCGGTAGTGTCGTATTGGCAGCGGGCAAAGCAAAATCCCGATGGATATCAAACGTCTCTGCCGGGACTGA
TGGACTTTCCCCTCTATGAAGTCTTATTGCAGGCAGTCAATGAGGAAGAGCGCTGGGGCACAGGCCTTATCCGCCTCTAT
GAGGCCCTTGCCAACGATATGCTCTATCCCCATGCCCAAAATCTGGTGCTGTTTGAAGGCAACCACGACACCAACCGCCT
CTACAGCCTGCTTGGGCGCGATATGAACAAGTTCAAGCTCGCGCTTGCCTACGTGCTCTTGTCAAACCGGGTGCCGCAGA
TTTTCTATGGCACTGAATTTGCCATGCAAAGTCCTGTTGAGGGGCGCAACGACGGCGCCGTGCGGGCGGATATGCCCGGC
TTCGGCAAGGCCGGATTCAGTAAGTCAGACATAGATGCCATGGCGGGCGACTCAAAAACGGCCTTTGAGTTTATCCGTGC
ATTGCTGCATTTTCGTAAAACCAGTGATGCGGTGCACAGGGGCAAACTGGTTCATTTTGTGCCACAAAGTGGCCTTTATG
TGCAGCTGAGACAAGCACCAGATGATAACCCTGACGCCAAAAATCTGATGGTTATCTTTAATAAAAACAAAGATTCTGTG
AGTCTGGATATGGGGCACTTCACCGATTTCCTGCCCCTGAACACGGACGTAAAGAGTGTGCTCGATAACAGGCATTTTTC
ATTACCGGCCACACTCACTGTGTCATCCCCCGTTACCCTGCTGGAGTTTTAA

Upstream 100 bases:

>100_bases
TGAGCTACTCAATGTAAGCAGCTTTTTGAAAGCGGCACCCTGAAAAGACCTGCCCCAGGGCAGGTCTTTTTATTTGTTTT
CCGGTCAACAGGAGGTTGCA

Downstream 100 bases:

>100_bases
TCCCCATGGCATTTGTTTCTTCTCGCCGCATTTCCCTGCTGGCCCTGACCAGCCTGACAGCCCTGCTCGGCTGCAACGTG
CCACACAATAGCAACACGGA

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Beta-amylase; Alpha-amylase [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MEQLTLSAQGAAIHSRVARRLCLTVFIGLSAATSTAALCVPMQGHENALNSNTLNPLSLSQAPHSGHGVTSSSVKVEQVK
VEPLNWWVGMENPQLELMITGEGVAHSTLRLENALGAKLLEIIPGDSPNYLFVKLDLSTASTGILTLVLSRPASTINPAT
DLTIPYELKARAPGSKERQGYGNRDVMYLITPDRFANGDKANDNLPGFDDKPSNPVYSEPGNSRDNARHGGDLAGIEHRL
DYLNDLGVTQLWLNPLLENRQPAYSYHGYAITDFYQIDARFGSNAQYQALVRKAADRGLGVIMDVVLNHMGSGHPWMQDL
PFNDWVNPRSMHTSHRRTAVQDPYAAPKDAAAFTDGWFVDSMPDLNQRNPHLATYLIQNNLWWIEYAGLSGLRIDTWSYS
DKHFLKAFSEAIMAEYPHFNMVGEEWSGNPAVVSYWQRAKQNPDGYQTSLPGLMDFPLYEVLLQAVNEEERWGTGLIRLY
EALANDMLYPHAQNLVLFEGNHDTNRLYSLLGRDMNKFKLALAYVLLSNRVPQIFYGTEFAMQSPVEGRNDGAVRADMPG
FGKAGFSKSDIDAMAGDSKTAFEFIRALLHFRKTSDAVHRGKLVHFVPQSGLYVQLRQAPDDNPDAKNLMVIFNKNKDSV
SLDMGHFTDFLPLNTDVKSVLDNRHFSLPATLTVSSPVTLLEF

Sequences:

>Translated_683_residues
MEQLTLSAQGAAIHSRVARRLCLTVFIGLSAATSTAALCVPMQGHENALNSNTLNPLSLSQAPHSGHGVTSSSVKVEQVK
VEPLNWWVGMENPQLELMITGEGVAHSTLRLENALGAKLLEIIPGDSPNYLFVKLDLSTASTGILTLVLSRPASTINPAT
DLTIPYELKARAPGSKERQGYGNRDVMYLITPDRFANGDKANDNLPGFDDKPSNPVYSEPGNSRDNARHGGDLAGIEHRL
DYLNDLGVTQLWLNPLLENRQPAYSYHGYAITDFYQIDARFGSNAQYQALVRKAADRGLGVIMDVVLNHMGSGHPWMQDL
PFNDWVNPRSMHTSHRRTAVQDPYAAPKDAAAFTDGWFVDSMPDLNQRNPHLATYLIQNNLWWIEYAGLSGLRIDTWSYS
DKHFLKAFSEAIMAEYPHFNMVGEEWSGNPAVVSYWQRAKQNPDGYQTSLPGLMDFPLYEVLLQAVNEEERWGTGLIRLY
EALANDMLYPHAQNLVLFEGNHDTNRLYSLLGRDMNKFKLALAYVLLSNRVPQIFYGTEFAMQSPVEGRNDGAVRADMPG
FGKAGFSKSDIDAMAGDSKTAFEFIRALLHFRKTSDAVHRGKLVHFVPQSGLYVQLRQAPDDNPDAKNLMVIFNKNKDSV
SLDMGHFTDFLPLNTDVKSVLDNRHFSLPATLTVSSPVTLLEF
>Mature_683_residues
MEQLTLSAQGAAIHSRVARRLCLTVFIGLSAATSTAALCVPMQGHENALNSNTLNPLSLSQAPHSGHGVTSSSVKVEQVK
VEPLNWWVGMENPQLELMITGEGVAHSTLRLENALGAKLLEIIPGDSPNYLFVKLDLSTASTGILTLVLSRPASTINPAT
DLTIPYELKARAPGSKERQGYGNRDVMYLITPDRFANGDKANDNLPGFDDKPSNPVYSEPGNSRDNARHGGDLAGIEHRL
DYLNDLGVTQLWLNPLLENRQPAYSYHGYAITDFYQIDARFGSNAQYQALVRKAADRGLGVIMDVVLNHMGSGHPWMQDL
PFNDWVNPRSMHTSHRRTAVQDPYAAPKDAAAFTDGWFVDSMPDLNQRNPHLATYLIQNNLWWIEYAGLSGLRIDTWSYS
DKHFLKAFSEAIMAEYPHFNMVGEEWSGNPAVVSYWQRAKQNPDGYQTSLPGLMDFPLYEVLLQAVNEEERWGTGLIRLY
EALANDMLYPHAQNLVLFEGNHDTNRLYSLLGRDMNKFKLALAYVLLSNRVPQIFYGTEFAMQSPVEGRNDGAVRADMPG
FGKAGFSKSDIDAMAGDSKTAFEFIRALLHFRKTSDAVHRGKLVHFVPQSGLYVQLRQAPDDNPDAKNLMVIFNKNKDSV
SLDMGHFTDFLPLNTDVKSVLDNRHFSLPATLTVSSPVTLLEF

Specific function: The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=473, Percent_Identity=24.7357293868922, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1789995, Length=137, Percent_Identity=35.7664233576642, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790687, Length=188, Percent_Identity=27.6595744680851, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322245, Length=101, Percent_Identity=34.6534653465347, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321726, Length=196, Percent_Identity=25, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322241, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322021, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324416, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319776, Length=196, Percent_Identity=25.5102040816327, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321731, Length=196, Percent_Identity=25.5102040816327, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583745, Length=194, Percent_Identity=30.4123711340206, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330053, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24586599, Length=193, Percent_Identity=27.979274611399, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45549022, Length=199, Percent_Identity=28.643216080402, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583749, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583747, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586597, Length=181, Percent_Identity=29.2817679558011, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24586587, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24586593, Length=191, Percent_Identity=29.3193717277487, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24586591, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006048
- InterPro:   IPR005085
- InterPro:   IPR008985
- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR001554
- InterPro:   IPR018238
- InterPro:   IPR000125
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF03423 CBM_25; PF01373 Glyco_hydro_14 [H]

EC number: =3.2.1.2; =3.2.1.1 [H]

Molecular weight: Translated: 75960; Mature: 75960

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLTLSAQGAAIHSRVARRLCLTVFIGLSAATSTAALCVPMQGHENALNSNTLNPLSLS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
QAPHSGHGVTSSSVKVEQVKVEPLNWWVGMENPQLELMITGEGVAHSTLRLENALGAKLL
CCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
EIIPGDSPNYLFVKLDLSTASTGILTLVLSRPASTINPATDLTIPYELKARAPGSKERQG
HHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEECEEEECCCCCCHHHCC
YGNRDVMYLITPDRFANGDKANDNLPGFDDKPSNPVYSEPGNSRDNARHGGDLAGIEHRL
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DYLNDLGVTQLWLNPLLENRQPAYSYHGYAITDFYQIDARFGSNAQYQALVRKAADRGLG
HHHHCCCHHHHHHHHHHHCCCCCCEECCEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHH
VIMDVVLNHMGSGHPWMQDLPFNDWVNPRSMHTSHRRTAVQDPYAAPKDAAAFTDGWFVD
HHHHHHHHHCCCCCCCHHCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEEC
SMPDLNQRNPHLATYLIQNNLWWIEYAGLSGLRIDTWSYSDKHFLKAFSEAIMAEYPHFN
CCCCCCCCCCCEEEEEEECCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCC
MVGEEWSGNPAVVSYWQRAKQNPDGYQTSLPGLMDFPLYEVLLQAVNEEERWGTGLIRLY
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
EALANDMLYPHAQNLVLFEGNHDTNRLYSLLGRDMNKFKLALAYVLLSNRVPQIFYGTEF
HHHHHCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHH
AMQSPVEGRNDGAVRADMPGFGKAGFSKSDIDAMAGDSKTAFEFIRALLHFRKTSDAVHR
HHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
GKLVHFVPQSGLYVQLRQAPDDNPDAKNLMVIFNKNKDSVSLDMGHFTDFLPLNTDVKSV
CCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCHHHHH
LDNRHFSLPATLTVSSPVTLLEF
HCCCCCCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MEQLTLSAQGAAIHSRVARRLCLTVFIGLSAATSTAALCVPMQGHENALNSNTLNPLSLS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
QAPHSGHGVTSSSVKVEQVKVEPLNWWVGMENPQLELMITGEGVAHSTLRLENALGAKLL
CCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
EIIPGDSPNYLFVKLDLSTASTGILTLVLSRPASTINPATDLTIPYELKARAPGSKERQG
HHCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEECEEEECCCCCCHHHCC
YGNRDVMYLITPDRFANGDKANDNLPGFDDKPSNPVYSEPGNSRDNARHGGDLAGIEHRL
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
DYLNDLGVTQLWLNPLLENRQPAYSYHGYAITDFYQIDARFGSNAQYQALVRKAADRGLG
HHHHCCCHHHHHHHHHHHCCCCCCEECCEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHH
VIMDVVLNHMGSGHPWMQDLPFNDWVNPRSMHTSHRRTAVQDPYAAPKDAAAFTDGWFVD
HHHHHHHHHCCCCCCCHHCCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCCCCCCCCEEC
SMPDLNQRNPHLATYLIQNNLWWIEYAGLSGLRIDTWSYSDKHFLKAFSEAIMAEYPHFN
CCCCCCCCCCCEEEEEEECCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCC
MVGEEWSGNPAVVSYWQRAKQNPDGYQTSLPGLMDFPLYEVLLQAVNEEERWGTGLIRLY
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHH
EALANDMLYPHAQNLVLFEGNHDTNRLYSLLGRDMNKFKLALAYVLLSNRVPQIFYGTEF
HHHHHCCCCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCHH
AMQSPVEGRNDGAVRADMPGFGKAGFSKSDIDAMAGDSKTAFEFIRALLHFRKTSDAVHR
HHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
GKLVHFVPQSGLYVQLRQAPDDNPDAKNLMVIFNKNKDSVSLDMGHFTDFLPLNTDVKSV
CCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCHHHHH
LDNRHFSLPATLTVSSPVTLLEF
HCCCCCCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2435707; 2464578; 2438660; 1827035 [H]