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The map label for this gene is hlyB [H]

Identifier: 119774789

GI number: 119774789

Start: 2017088

End: 2018704

Strand: Reverse

Name: hlyB [H]

Synonym: Sama_1653

Alternate gene names: 119774789

Gene position: 2018704-2017088 (Counterclockwise)

Preceding gene: 119774792

Following gene: 119774788

Centisome position: 46.88

GC content: 54.92

Gene sequence:

>1617_bases
ATGATTGCCTTCCTCAGAAAATTCACCATCTTACAGCGTCTTATCATGATGCTGGCGCTGGCAGCCCTTGGCACCTTTTG
CTTTGCGGCCTTTAATATCCAGGAACAGTACAACAACCTTGAGCAGCAAAAATGGCTGCAAAATGATGGCCAGTTGGATA
CTGTGCTGTCGCTGGTAGAGGTGCACAGGCAACAGGTGCAGCAGGGTCAAATCAGCGAAGCAGATGCCAAGGCAGAAGTG
GCGAGTCTTATCAATGCAGCTCATTACGGCAATGGTGGCTACTTTATGGTGGTGGATGCTGAGGGTCAGATCCTCGCTGC
CGGTGGCCAGTCGCAGAAAATCGGTAGCCGTGTCAGCGACAAGTCTATCCTGAATCTGGTCAATGAAGCCCGCACCAAGG
GCAAAGCGGTTGCCACAGTAGAGACCCTTAACCCGGACACAGGCAAAACCGACACCCAGTTGGCTGAAGCACGTCAATTT
GCCCCCTGGCAGTGGATTGTCATCACCGGTGCCTTTGTGGCCGATGTCAATGCCGCCATGGAAACCGCCATCTGGAATAC
CCTCATCATTATGATGTTGATTTCCACACCACTGTTTGCCCTCTTTATGGCGCTCAATCATTCTATTACCTCGCCCCTTA
ACCGTGCCATTGAGGCGCTGGAAGACATCGCCGACGGCGAAGGGGATCTGGGAGCGAGACTGAGCACCGCAGGCAAAGAT
GAGGTAGCTCACCTTGCCAAGGCCTTTAATCGCTTCGCCGAAAAAATCGGTAAGTTAATTAAAGACATCAAACCCATGGG
CGATGAACTGACCGATGATGCCCAGGCCCTGAGTCAGGCGGTTGAAACCGCCAATCGCAGCAGTGAACAAATCCATCGGG
AGACTGAAAGCGTTGCCGCCGCCATTCATCAAATGCTGGCCACGAGCCAGGAAATGGCCCACAACACCCAGCAGGCTGCC
GATTCGGCTTCCAAGGTAAAGGGACAGGCTCAGGAGAGCCAGTCGCTGATGACCAGCACGCTGAAGCAAACTGAATCCCT
GGTAGACAAGCTGAAGGCGGCAGAGCTGACTACGGCCCGACTTGGCGCCGCCTCAGGTCAGATTGGCAGCATTCTCGATG
TTATCCGCGCCATTGCCGAACAGACCAACCTGCTCGCCCTCAATGCCGCTATTGAAGCGGCCCGTGCCGGCGCCCACGGT
CGCGGTTTTGCGGTTGTGGCCGATGAAGTGCGTGCCCTCGCCAACCGCACCCAGCAGTCCACCAATGAAATTCAAAAAAT
TATCAGCGAAATTCAGGCCGGTATCGGCGATGTAACCGCCTCCAACAGTGCCAATCAGACACTGTCTGAATCGCTGCAGA
GCCAGGCCCGTCAGGCAGGCGCCTCCATGGACGCCATCTTGTCGCTGGTCGCCCACATTAACGACATCAACACTCAGCTT
GCCAGTGCGACTGAAGAGCAGTCGCTGGTGACCGAAGAAATCAATCGCAACATCAGCAATATTTCAGAGCAAATGCAGCT
GGCGGTTGAGTCCAACGAAGGTAATCGACATGCCGCAGGCTCGCTGCAATCCATCAGCCGGGCACTGGCCAAGGCCCTTG
GGCATTTCAAGGTATAG

Upstream 100 bases:

>100_bases
CGGATTTACACTTTTACCCCGGGATTTACACCAAGGTCGCACAGATTGACCATAGCTATCTGATAGACTCTTGCCTGCCC
TACAGATTACGGAGACGGCC

Downstream 100 bases:

>100_bases
TGGCATTCAGTTAATGAAAACATAAAAAGGGGGACCACAGGGTCCCCCTTTTTATGCGGGCGAATTGTGCTAGGCTAGGC
CTTAACCCATGCACACAAGC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MIAFLRKFTILQRLIMMLALAALGTFCFAAFNIQEQYNNLEQQKWLQNDGQLDTVLSLVEVHRQQVQQGQISEADAKAEV
ASLINAAHYGNGGYFMVVDAEGQILAAGGQSQKIGSRVSDKSILNLVNEARTKGKAVATVETLNPDTGKTDTQLAEARQF
APWQWIVITGAFVADVNAAMETAIWNTLIIMMLISTPLFALFMALNHSITSPLNRAIEALEDIADGEGDLGARLSTAGKD
EVAHLAKAFNRFAEKIGKLIKDIKPMGDELTDDAQALSQAVETANRSSEQIHRETESVAAAIHQMLATSQEMAHNTQQAA
DSASKVKGQAQESQSLMTSTLKQTESLVDKLKAAELTTARLGAASGQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHG
RGFAVVADEVRALANRTQQSTNEIQKIISEIQAGIGDVTASNSANQTLSESLQSQARQAGASMDAILSLVAHINDINTQL
ASATEEQSLVTEEINRNISNISEQMQLAVESNEGNRHAAGSLQSISRALAKALGHFKV

Sequences:

>Translated_538_residues
MIAFLRKFTILQRLIMMLALAALGTFCFAAFNIQEQYNNLEQQKWLQNDGQLDTVLSLVEVHRQQVQQGQISEADAKAEV
ASLINAAHYGNGGYFMVVDAEGQILAAGGQSQKIGSRVSDKSILNLVNEARTKGKAVATVETLNPDTGKTDTQLAEARQF
APWQWIVITGAFVADVNAAMETAIWNTLIIMMLISTPLFALFMALNHSITSPLNRAIEALEDIADGEGDLGARLSTAGKD
EVAHLAKAFNRFAEKIGKLIKDIKPMGDELTDDAQALSQAVETANRSSEQIHRETESVAAAIHQMLATSQEMAHNTQQAA
DSASKVKGQAQESQSLMTSTLKQTESLVDKLKAAELTTARLGAASGQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHG
RGFAVVADEVRALANRTQQSTNEIQKIISEIQAGIGDVTASNSANQTLSESLQSQARQAGASMDAILSLVAHINDINTQL
ASATEEQSLVTEEINRNISNISEQMQLAVESNEGNRHAAGSLQSISRALAKALGHFKV
>Mature_538_residues
MIAFLRKFTILQRLIMMLALAALGTFCFAAFNIQEQYNNLEQQKWLQNDGQLDTVLSLVEVHRQQVQQGQISEADAKAEV
ASLINAAHYGNGGYFMVVDAEGQILAAGGQSQKIGSRVSDKSILNLVNEARTKGKAVATVETLNPDTGKTDTQLAEARQF
APWQWIVITGAFVADVNAAMETAIWNTLIIMMLISTPLFALFMALNHSITSPLNRAIEALEDIADGEGDLGARLSTAGKD
EVAHLAKAFNRFAEKIGKLIKDIKPMGDELTDDAQALSQAVETANRSSEQIHRETESVAAAIHQMLATSQEMAHNTQQAA
DSASKVKGQAQESQSLMTSTLKQTESLVDKLKAAELTTARLGAASGQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHG
RGFAVVADEVRALANRTQQSTNEIQKIISEIQAGIGDVTASNSANQTLSESLQSQARQAGASMDAILSLVAHINDINTQL
ASATEEQSLVTEEINRNISNISEQMQLAVESNEGNRHAAGSLQSISRALAKALGHFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=31.9620253164557, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787690, Length=391, Percent_Identity=32.2250639386189, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788195, Length=287, Percent_Identity=30.3135888501742, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=285, Percent_Identity=31.2280701754386, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789453, Length=273, Percent_Identity=29.6703296703297, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 57608; Mature: 57608

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFLRKFTILQRLIMMLALAALGTFCFAAFNIQEQYNNLEQQKWLQNDGQLDTVLSLVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHH
VHRQQVQQGQISEADAKAEVASLINAAHYGNGGYFMVVDAEGQILAAGGQSQKIGSRVSD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHHHH
KSILNLVNEARTKGKAVATVETLNPDTGKTDTQLAEARQFAPWQWIVITGAFVADVNAAM
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
ETAIWNTLIIMMLISTPLFALFMALNHSITSPLNRAIEALEDIADGEGDLGARLSTAGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHH
EVAHLAKAFNRFAEKIGKLIKDIKPMGDELTDDAQALSQAVETANRSSEQIHRETESVAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AIHQMLATSQEMAHNTQQAADSASKVKGQAQESQSLMTSTLKQTESLVDKLKAAELTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAASGQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHGRGFAVVADEVRALANRTQQS
HCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TNEIQKIISEIQAGIGDVTASNSANQTLSESLQSQARQAGASMDAILSLVAHINDINTQL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ASATEEQSLVTEEINRNISNISEQMQLAVESNEGNRHAAGSLQSISRALAKALGHFKV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIAFLRKFTILQRLIMMLALAALGTFCFAAFNIQEQYNNLEQQKWLQNDGQLDTVLSLVE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHH
VHRQQVQQGQISEADAKAEVASLINAAHYGNGGYFMVVDAEGQILAAGGQSQKIGSRVSD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCHHHHHHHHH
KSILNLVNEARTKGKAVATVETLNPDTGKTDTQLAEARQFAPWQWIVITGAFVADVNAAM
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEEHHHHHHHHHHH
ETAIWNTLIIMMLISTPLFALFMALNHSITSPLNRAIEALEDIADGEGDLGARLSTAGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHH
EVAHLAKAFNRFAEKIGKLIKDIKPMGDELTDDAQALSQAVETANRSSEQIHRETESVAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AIHQMLATSQEMAHNTQQAADSASKVKGQAQESQSLMTSTLKQTESLVDKLKAAELTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAASGQIGSILDVIRAIAEQTNLLALNAAIEAARAGAHGRGFAVVADEVRALANRTQQS
HCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TNEIQKIISEIQAGIGDVTASNSANQTLSESLQSQARQAGASMDAILSLVAHINDINTQL
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ASATEEQSLVTEEINRNISNISEQMQLAVESNEGNRHAAGSLQSISRALAKALGHFKV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]