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The map label for this gene is argD [H]

Identifier: 119774765

GI number: 119774765

Start: 1992953

End: 1994170

Strand: Reverse

Name: argD [H]

Synonym: Sama_1628

Alternate gene names: 119774765

Gene position: 1994170-1992953 (Counterclockwise)

Preceding gene: 119774767

Following gene: 229220633

Centisome position: 46.31

GC content: 57.22

Gene sequence:

>1218_bases
ATGCATATCAACAGAAGTTTATTCGATGAAGTGATGGTTCCCAACTACGCGCCATCCCCTATCATTCCGGTAAAGGGCCT
GGGGTCACGCCTGTGGGATCAGCAAGGCCGCGAGTTTATCGATTTCGCCGGTGGCATTGCCGTGAACTGTCTGGGCCATT
GTCACCCAGCCCTGGTGTCTGCCCTCACCGAGCAGGCACAAAAACTGTGGCACCTGTCCAACACCATGACCAACGAGCCA
GCGCTGATGCTGGCCAAACACTTGGTTGATAACACCTTTGCCGAGAAGGTCTACTTTGCCAACTCAGGCGCCGAAGCCAA
CGAGGCTGCCCTGAAGCTGGTTCGCCGCGTGGCATTGAACAAGTTTGGCGCTGATAAGTCACAGATCATCGCCTTCAAAC
AAGGCTTCCATGGCCGCACCCTGTTTACCGTATCCGTGGGTGGCCAGCCTGCCTACTCCGATGGTTTTGGCCCCAAGCCA
GCCGATATCGACCATGCCGAATACAACAATCTCGACAGCCTGAAGGCGCTGATTTCAGATCGTACCTGCGCCGTGGTACT
GGAGCCGCTGCAGGGCGAAGGCGGCATCATCAACCCAACCCCTGAGTTCATCAAGGGCGTACGTGAGCTGTGTGACCAGC
ACAATGCACTGCTGGTATTCGATGAAGTACAAACCGGCGTCGGCCGCACCGGCGAGCTTTATGCCTATATGGGCCTGGGC
GTTACCCCGGATGTACTGACCACAGCCAAGGCCCTTGGCGGTGGTTTCCCCATTGGCGCCATGTTGACCACCACTGAACT
GGCAAAGCATCTGGTTGTAGGCACCCACGGCAGCACCTACGGCGGTAACCCGCTGGCCTGTGCCGTTGGCCTTGCCGCAT
TCACCACAGTAAATACCCCGGAAGTACTGAATGGCGTGAAAGAGCGCGAACAGCTGTTCCGTGATGGCCTCAATGCCATC
AACGACAAGTATCAGGTATTCACCGAAGTGCGTGGTAAGGGTCTGCTGCTGGGCGCTGCGCTTAATGCGGATTACGCCGG
TAAAGCCCGTGACTTTATGCTGGCCGCCGCTGAAGAAGGCGTGCTCCTGCTGATGGCCGGTCAAAACGTGGTGCGTTTTG
CCCCTTCTCTTATCATTCCTGAGGCAGACGTTCGGGAAGGCCTGGCGCGTTTCGACGCCGCCATCGCCAAATTGGTTGCC
AGGCTTAACGCCGGTTAA

Upstream 100 bases:

>100_bases
CGCTGCTGCAAATTGCAACTTCTGCTCAATATAATACAGGGATAACTAAAGAAAGGGCCTTGAGCCCGACGATAAAACAA
TACAAAAACAGAGGCTTTGC

Downstream 100 bases:

>100_bases
ACCGCCTTAGGCATTTGTGCGAACAGGCGATGGGGCTTTGCCCTTTCGCCTTCCACACAGACCAAGAGAACCGAATTATG
TTACTTATCCGTCCTATACA

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MHINRSLFDEVMVPNYAPSPIIPVKGLGSRLWDQQGREFIDFAGGIAVNCLGHCHPALVSALTEQAQKLWHLSNTMTNEP
ALMLAKHLVDNTFAEKVYFANSGAEANEAALKLVRRVALNKFGADKSQIIAFKQGFHGRTLFTVSVGGQPAYSDGFGPKP
ADIDHAEYNNLDSLKALISDRTCAVVLEPLQGEGGIINPTPEFIKGVRELCDQHNALLVFDEVQTGVGRTGELYAYMGLG
VTPDVLTTAKALGGGFPIGAMLTTTELAKHLVVGTHGSTYGGNPLACAVGLAAFTTVNTPEVLNGVKEREQLFRDGLNAI
NDKYQVFTEVRGKGLLLGAALNADYAGKARDFMLAAAEEGVLLLMAGQNVVRFAPSLIIPEADVREGLARFDAAIAKLVA
RLNAG

Sequences:

>Translated_405_residues
MHINRSLFDEVMVPNYAPSPIIPVKGLGSRLWDQQGREFIDFAGGIAVNCLGHCHPALVSALTEQAQKLWHLSNTMTNEP
ALMLAKHLVDNTFAEKVYFANSGAEANEAALKLVRRVALNKFGADKSQIIAFKQGFHGRTLFTVSVGGQPAYSDGFGPKP
ADIDHAEYNNLDSLKALISDRTCAVVLEPLQGEGGIINPTPEFIKGVRELCDQHNALLVFDEVQTGVGRTGELYAYMGLG
VTPDVLTTAKALGGGFPIGAMLTTTELAKHLVVGTHGSTYGGNPLACAVGLAAFTTVNTPEVLNGVKEREQLFRDGLNAI
NDKYQVFTEVRGKGLLLGAALNADYAGKARDFMLAAAEEGVLLLMAGQNVVRFAPSLIIPEADVREGLARFDAAIAKLVA
RLNAG
>Mature_405_residues
MHINRSLFDEVMVPNYAPSPIIPVKGLGSRLWDQQGREFIDFAGGIAVNCLGHCHPALVSALTEQAQKLWHLSNTMTNEP
ALMLAKHLVDNTFAEKVYFANSGAEANEAALKLVRRVALNKFGADKSQIIAFKQGFHGRTLFTVSVGGQPAYSDGFGPKP
ADIDHAEYNNLDSLKALISDRTCAVVLEPLQGEGGIINPTPEFIKGVRELCDQHNALLVFDEVQTGVGRTGELYAYMGLG
VTPDVLTTAKALGGGFPIGAMLTTTELAKHLVVGTHGSTYGGNPLACAVGLAAFTTVNTPEVLNGVKEREQLFRDGLNAI
NDKYQVFTEVRGKGLLLGAALNADYAGKARDFMLAAAEEGVLLLMAGQNVVRFAPSLIIPEADVREGLARFDAAIAKLVA
RLNAG

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=35.8441558441558, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=36.7892976588629, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI13994255, Length=441, Percent_Identity=26.0770975056689, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=26.603325415677, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=25.462962962963, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442709, Length=386, Percent_Identity=26.9430051813472, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226442705, Length=421, Percent_Identity=25.41567695962, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=23.6144578313253, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=23.6144578313253, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=23.6144578313253, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=62.9722921914358, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1788044, Length=399, Percent_Identity=63.9097744360902, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=34.9009900990099, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI145693181, Length=319, Percent_Identity=37.6175548589342, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=33.2493702770781, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786991, Length=413, Percent_Identity=30.0242130750605, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786349, Length=317, Percent_Identity=32.1766561514196, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=34.4827586206897, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI32564660, Length=426, Percent_Identity=30.9859154929577, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=34.5724907063197, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=27.9445727482679, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71981843, Length=169, Percent_Identity=31.9526627218935, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=419, Percent_Identity=25.7756563245823, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=402, Percent_Identity=36.5671641791045, Blast_Score=249, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.9875930521092, Blast_Score=219, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=340, Percent_Identity=28.2352941176471, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=441, Percent_Identity=23.3560090702948, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=36.9393139841689, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=29.1284403669725, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=29.2056074766355, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21356575, Length=372, Percent_Identity=27.4193548387097, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281366494, Length=431, Percent_Identity=25.0580046403712, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667139, Length=431, Percent_Identity=25.0580046403712, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667143, Length=431, Percent_Identity=25.0580046403712, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43242; Mature: 43242

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHINRSLFDEVMVPNYAPSPIIPVKGLGSRLWDQQGREFIDFAGGIAVNCLGHCHPALVS
CCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
ALTEQAQKLWHLSNTMTNEPALMLAKHLVDNTFAEKVYFANSGAEANEAALKLVRRVALN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
KFGADKSQIIAFKQGFHGRTLFTVSVGGQPAYSDGFGPKPADIDHAEYNNLDSLKALISD
HCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHCC
RTCAVVLEPLQGEGGIINPTPEFIKGVRELCDQHNALLVFDEVQTGVGRTGELYAYMGLG
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEECCC
VTPDVLTTAKALGGGFPIGAMLTTTELAKHLVVGTHGSTYGGNPLACAVGLAAFTTVNTP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHCCCCH
EVLNGVKEREQLFRDGLNAINDKYQVFTEVRGKGLLLGAALNADYAGKARDFMLAAAEEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHEEEECCCC
VLLLMAGQNVVRFAPSLIIPEADVREGLARFDAAIAKLVARLNAG
EEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHINRSLFDEVMVPNYAPSPIIPVKGLGSRLWDQQGREFIDFAGGIAVNCLGHCHPALVS
CCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHH
ALTEQAQKLWHLSNTMTNEPALMLAKHLVDNTFAEKVYFANSGAEANEAALKLVRRVALN
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHH
KFGADKSQIIAFKQGFHGRTLFTVSVGGQPAYSDGFGPKPADIDHAEYNNLDSLKALISD
HCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHCC
RTCAVVLEPLQGEGGIINPTPEFIKGVRELCDQHNALLVFDEVQTGVGRTGELYAYMGLG
CCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEECCC
VTPDVLTTAKALGGGFPIGAMLTTTELAKHLVVGTHGSTYGGNPLACAVGLAAFTTVNTP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHCCCCH
EVLNGVKEREQLFRDGLNAINDKYQVFTEVRGKGLLLGAALNADYAGKARDFMLAAAEEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHEEEECCCC
VLLLMAGQNVVRFAPSLIIPEADVREGLARFDAAIAKLVARLNAG
EEEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]