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The map label for this gene is mdtA [H]

Identifier: 119774558

GI number: 119774558

Start: 1730065

End: 1731129

Strand: Reverse

Name: mdtA [H]

Synonym: Sama_1421

Alternate gene names: 119774558

Gene position: 1731129-1730065 (Counterclockwise)

Preceding gene: 119774559

Following gene: 119774557

Centisome position: 40.2

GC content: 53.99

Gene sequence:

>1065_bases
ATGGAAGCCCGCAAATCATTCAAACTCGCCCTCCCCTTACTGCTTGTTGGTGTACTCGCCGCCTGTGGACAGGAAGAAGC
CAAGAAGGAAGAAGAAAAATACGCCATACCTGTTGAAACCCAGTTAGTGGTTCAGGGCAATGTTTCCTCATTCTATTCCA
CCACCGCCACCCTCGAAGCACCGGTCGAGGCCCATGTTGTGACCCGTATCGCTGGCCTGATAGAAGCCCTGCACGTAGAA
GAAGGCGACAGAGTCAAACAAGGGCAATTGCTGGCCGTCATCGACGCCAAGCGTCAGCAGTATGAGCTAGACCGCTCCGA
AGCCGAAGTGCTCATCATCGAGCAAGAGCTAGCGCGGGTGAAAAAGATGAAGAGCAAAGACTATGTCAGCGCCGACTCCA
TCGCCAAACTCGAATACAACCTGCAGGCCGCCAAGGCGCGCCTGGACCTGGCGAAACTGCAGGTTAAAGAGAGCCAAATC
GTGTCCCCCGTGGATGGCATCATCGCCAAGCGCTTCGTTAAAGCCGGCAACATGGCCAAAGAATTCGAAGAGCTCTTCTA
TGTGGTCAATCAGGACGAGCTTCACGGGATAGTGCATCTGCCGGAGCAGCAGCTCTCCAGCCTGCGTCTTGGACAGCATG
CCGATATCTACGCCAGCGGTCAGAAAAACCAGGCCGTGAATGCCGAAGTACTGCGCATCAGCCCGGTCGTTGACGCCCAG
AGCGGCACCTTCAAGGTCACGCTCAAGGTGCCCAATCAAAATGGCATCCTTAAGTCGGGTATGTTTACCCGGGTGGAACT
TAAGTACGACACCCATGAAAACGTCATCACAGTGCCTTACAACGCCATCATCAACCAGGATAACAAGCAAACCCTGTATG
TTGTCCAGGACACCACGGCCGAGCGTCGCGAAGTAGAGCTGGGTTATCGTGAAGGCAACATGGTTGAAGTCGTTGCGGGT
ATTGCTCCCGGAGAGCATCTGGTGATCCGTGGGCAGCAAAACCTCAAAGACCAGTCGCTGGTTGAAATCATCACCCCACT
GGATGTGGCTTCGGTTAAAAAATAA

Upstream 100 bases:

>100_bases
AAGCTAATTTATCGCTATCTTATTGTAATAAATGAATTATCCAATTCTGGCACGGAAGCTGCTTTTAAAGCGCAACACAG
TTAACAGTACAGGTATAACA

Downstream 100 bases:

>100_bases
GGAGCACATCCCATGTCAATAATCACGACTTCCGTTCAACGGCCGGTCACCGTGTGGATGTTTATGCTCGCGGTGATCCT
CTTCGGTATGGTGGGCTTCT

Product: HlyD family secretion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEARKSFKLALPLLLVGVLAACGQEEAKKEEEKYAIPVETQLVVQGNVSSFYSTTATLEAPVEAHVVTRIAGLIEALHVE
EGDRVKQGQLLAVIDAKRQQYELDRSEAEVLIIEQELARVKKMKSKDYVSADSIAKLEYNLQAAKARLDLAKLQVKESQI
VSPVDGIIAKRFVKAGNMAKEFEELFYVVNQDELHGIVHLPEQQLSSLRLGQHADIYASGQKNQAVNAEVLRISPVVDAQ
SGTFKVTLKVPNQNGILKSGMFTRVELKYDTHENVITVPYNAIINQDNKQTLYVVQDTTAERREVELGYREGNMVEVVAG
IAPGEHLVIRGQQNLKDQSLVEIITPLDVASVKK

Sequences:

>Translated_354_residues
MEARKSFKLALPLLLVGVLAACGQEEAKKEEEKYAIPVETQLVVQGNVSSFYSTTATLEAPVEAHVVTRIAGLIEALHVE
EGDRVKQGQLLAVIDAKRQQYELDRSEAEVLIIEQELARVKKMKSKDYVSADSIAKLEYNLQAAKARLDLAKLQVKESQI
VSPVDGIIAKRFVKAGNMAKEFEELFYVVNQDELHGIVHLPEQQLSSLRLGQHADIYASGQKNQAVNAEVLRISPVVDAQ
SGTFKVTLKVPNQNGILKSGMFTRVELKYDTHENVITVPYNAIINQDNKQTLYVVQDTTAERREVELGYREGNMVEVVAG
IAPGEHLVIRGQQNLKDQSLVEIITPLDVASVKK
>Mature_354_residues
MEARKSFKLALPLLLVGVLAACGQEEAKKEEEKYAIPVETQLVVQGNVSSFYSTTATLEAPVEAHVVTRIAGLIEALHVE
EGDRVKQGQLLAVIDAKRQQYELDRSEAEVLIIEQELARVKKMKSKDYVSADSIAKLEYNLQAAKARLDLAKLQVKESQI
VSPVDGIIAKRFVKAGNMAKEFEELFYVVNQDELHGIVHLPEQQLSSLRLGQHADIYASGQKNQAVNAEVLRISPVVDAQ
SGTFKVTLKVPNQNGILKSGMFTRVELKYDTHENVITVPYNAIINQDNKQTLYVVQDTTAERREVELGYREGNMVEVVAG
IAPGEHLVIRGQQNLKDQSLVEIITPLDVASVKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=331, Percent_Identity=23.8670694864048, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081796, Length=369, Percent_Identity=23.8482384823848, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789929, Length=368, Percent_Identity=26.6304347826087, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39253; Mature: 39253

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEARKSFKLALPLLLVGVLAACGQEEAKKEEEKYAIPVETQLVVQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEECCCEEEEEEECCCHHHHCCCEEEEC
PVEAHVVTRIAGLIEALHVEEGDRVKQGQLLAVIDAKRQQYELDRSEAEVLIIEQELARV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHCCCCCCEEEEEHHHHHHH
KKMKSKDYVSADSIAKLEYNLQAAKARLDLAKLQVKESQIVSPVDGIIAKRFVKAGNMAK
HHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHCCCHHH
EFEELFYVVNQDELHGIVHLPEQQLSSLRLGQHADIYASGQKNQAVNAEVLRISPVVDAQ
HHHHHHEEECCCCCCEEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEEEECC
SGTFKVTLKVPNQNGILKSGMFTRVELKYDTHENVITVPYNAIINQDNKQTLYVVQDTTA
CCEEEEEEEECCCCCCEECCCEEEEEEEECCCCCEEEECHHHEECCCCCEEEEEEECCCC
ERREVELGYREGNMVEVVAGIAPGEHLVIRGQQNLKDQSLVEIITPLDVASVKK
CCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MEARKSFKLALPLLLVGVLAACGQEEAKKEEEKYAIPVETQLVVQGNVSSFYSTTATLEA
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEECCCEEEEEEECCCHHHHCCCEEEEC
PVEAHVVTRIAGLIEALHVEEGDRVKQGQLLAVIDAKRQQYELDRSEAEVLIIEQELARV
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHCCCCCCEEEEEHHHHHHH
KKMKSKDYVSADSIAKLEYNLQAAKARLDLAKLQVKESQIVSPVDGIIAKRFVKAGNMAK
HHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHHCCCHHH
EFEELFYVVNQDELHGIVHLPEQQLSSLRLGQHADIYASGQKNQAVNAEVLRISPVVDAQ
HHHHHHEEECCCCCCEEEECCHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEEEEEECC
SGTFKVTLKVPNQNGILKSGMFTRVELKYDTHENVITVPYNAIINQDNKQTLYVVQDTTA
CCEEEEEEEECCCCCCEECCCEEEEEEEECCCCCEEEECHHHEECCCCCEEEEEEECCCC
ERREVELGYREGNMVEVVAGIAPGEHLVIRGQQNLKDQSLVEIITPLDVASVKK
CCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]