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The map label for this gene is suhB [H]

Identifier: 119774426

GI number: 119774426

Start: 1576636

End: 1577439

Strand: Reverse

Name: suhB [H]

Synonym: Sama_1289

Alternate gene names: 119774426

Gene position: 1577439-1576636 (Counterclockwise)

Preceding gene: 119774439

Following gene: 119774425

Centisome position: 36.63

GC content: 55.47

Gene sequence:

>804_bases
ATGCATCCGATGCTGACCATCGCTGTGCGCGCCGCTCGCGCCGCCGGCCAAACCATTATGCGTGCTTATACTGATCTCGA
CCGCGTCGAGGTGAGTACCAAAGGTATCAATGATTTTGTTACCAGCGTAGACAAGGAAGCCGAAGCAGCTATCGTTTACC
AGATCCGCAAATCTTATCCCGACCACACCATCGTTGGTGAAGAGCAGGGTGAAAACCGCGGTACGAACAAAGATTATATC
TGGATCGTTGACCCTCTGGATGGCACCACCAACTTTATGCGTGGTATCCCCCATTTCGCCGTTTCCATCGCCCTGCAATA
CAAAGGTAAAACTGAAGTTGCCGTAGTCTACGACCCGGTGCGTGACGAGCTGTTCAGCGCCGTCCGCGGTCAGGGCGCCA
AGGTAAACGACTTCCGCGTTCGCGTGAGCAACGTTCAGGACCTCAATGGCACCATCATCGCCACGGGTTTCCCATTCAAG
TCACGCCAACACACCCAGACCTACATGAACGTGCTCAACGAAGTGTTTGCCCAGTGCGCTGACCTTCGCCGCGCCGGAGC
AGCCTCTCTGGATCTGGCCTATGTCGCTGCCGGTCGCATGGATGGTTATTTCGAGCTTGGTCTCAAGCCGTGGGACATCG
CTGCCGGTGACCTGATTGTGCGTGAAGCCGGTGGTACTGTGACTGACTTTACCGGTGGTCACAACTATCTGATGTCCGGC
AACATAGTGGCTGGCTCACCCAAGGCGACTACCGCACTGGTGAAAACCATGCGTCCTCTTTTGAACGAAGCCCTCAAGCG
CTAA

Upstream 100 bases:

>100_bases
CGGTTAAATCCTTATATGAAAATCTGTAATTGATATACCCGGCAGATGCGGTATAATGCGCGCCGCTCATTTTTCGTTCT
TTAACATCCAGGGGATTGCA

Downstream 100 bases:

>100_bases
GATTCAGAAAAGATTCCTAATTCAAGAACCGCCTCACGGCGGTTTTTGTTTTTGTGCACCATATCAATTTACATGCATAT
TTTAAGCACCTTATAATAAC

Product: extragenic suppressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHPMLTIAVRAARAAGQTIMRAYTDLDRVEVSTKGINDFVTSVDKEAEAAIVYQIRKSYPDHTIVGEEQGENRGTNKDYI
WIVDPLDGTTNFMRGIPHFAVSIALQYKGKTEVAVVYDPVRDELFSAVRGQGAKVNDFRVRVSNVQDLNGTIIATGFPFK
SRQHTQTYMNVLNEVFAQCADLRRAGAASLDLAYVAAGRMDGYFELGLKPWDIAAGDLIVREAGGTVTDFTGGHNYLMSG
NIVAGSPKATTALVKTMRPLLNEALKR

Sequences:

>Translated_267_residues
MHPMLTIAVRAARAAGQTIMRAYTDLDRVEVSTKGINDFVTSVDKEAEAAIVYQIRKSYPDHTIVGEEQGENRGTNKDYI
WIVDPLDGTTNFMRGIPHFAVSIALQYKGKTEVAVVYDPVRDELFSAVRGQGAKVNDFRVRVSNVQDLNGTIIATGFPFK
SRQHTQTYMNVLNEVFAQCADLRRAGAASLDLAYVAAGRMDGYFELGLKPWDIAAGDLIVREAGGTVTDFTGGHNYLMSG
NIVAGSPKATTALVKTMRPLLNEALKR
>Mature_267_residues
MHPMLTIAVRAARAAGQTIMRAYTDLDRVEVSTKGINDFVTSVDKEAEAAIVYQIRKSYPDHTIVGEEQGENRGTNKDYI
WIVDPLDGTTNFMRGIPHFAVSIALQYKGKTEVAVVYDPVRDELFSAVRGQGAKVNDFRVRVSNVQDLNGTIIATGFPFK
SRQHTQTYMNVLNEVFAQCADLRRAGAASLDLAYVAAGRMDGYFELGLKPWDIAAGDLIVREAGGTVTDFTGGHNYLMSG
NIVAGSPKATTALVKTMRPLLNEALKR

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=260, Percent_Identity=33.4615384615385, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI5031789, Length=244, Percent_Identity=32.7868852459016, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=32.7868852459016, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI221625507, Length=140, Percent_Identity=35.7142857142857, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=63.6704119850187, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1790659, Length=207, Percent_Identity=29.951690821256, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=247, Percent_Identity=33.6032388663968, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193202572, Length=246, Percent_Identity=32.9268292682927, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320493, Length=202, Percent_Identity=37.6237623762376, Blast_Score=128, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321836, Length=206, Percent_Identity=32.0388349514563, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357329, Length=267, Percent_Identity=34.4569288389513, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24664926, Length=217, Percent_Identity=35.4838709677419, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24664922, Length=237, Percent_Identity=34.1772151898734, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21357957, Length=271, Percent_Identity=33.210332103321, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21357303, Length=249, Percent_Identity=29.718875502008, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24664918, Length=261, Percent_Identity=32.5670498084291, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29250; Mature: 29250

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLTIAVRAARAAGQTIMRAYTDLDRVEVSTKGINDFVTSVDKEAEAAIVYQIRKSYP
CCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEHHCCHHHHHHHCCCCHHHHHHHHHHHCCC
DHTIVGEEQGENRGTNKDYIWIVDPLDGTTNFMRGIPHFAVSIALQYKGKTEVAVVYDPV
CCEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEECCH
RDELFSAVRGQGAKVNDFRVRVSNVQDLNGTIIATGFPFKSRQHTQTYMNVLNEVFAQCA
HHHHHHHHCCCCCCEEHEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DLRRAGAASLDLAYVAAGRMDGYFELGLKPWDIAAGDLIVREAGGTVTDFTGGHNYLMSG
HHHHCCCCCCEEHEEECCCCCCEEEECCCCCCCCCCCEEEEECCCCEEECCCCCCEEEEC
NIVAGSPKATTALVKTMRPLLNEALKR
CEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPMLTIAVRAARAAGQTIMRAYTDLDRVEVSTKGINDFVTSVDKEAEAAIVYQIRKSYP
CCCCEEHHHHHHHHHHHHHHHHHHHHHHEEEHHCCHHHHHHHCCCCHHHHHHHHHHHCCC
DHTIVGEEQGENRGTNKDYIWIVDPLDGTTNFMRGIPHFAVSIALQYKGKTEVAVVYDPV
CCEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEECCCCEEEEEECCH
RDELFSAVRGQGAKVNDFRVRVSNVQDLNGTIIATGFPFKSRQHTQTYMNVLNEVFAQCA
HHHHHHHHCCCCCCEEHEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DLRRAGAASLDLAYVAAGRMDGYFELGLKPWDIAAGDLIVREAGGTVTDFTGGHNYLMSG
HHHHCCCCCCEEHEEECCCCCCEEEECCCCCCCCCCCEEEEECCCCEEECCCCCCEEEEC
NIVAGSPKATTALVKTMRPLLNEALKR
CEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]