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The map label for this gene is 119774382

Identifier: 119774382

GI number: 119774382

Start: 1528416

End: 1529333

Strand: Reverse

Name: 119774382

Synonym: Sama_1245

Alternate gene names: NA

Gene position: 1529333-1528416 (Counterclockwise)

Preceding gene: 119774383

Following gene: 119774381

Centisome position: 35.52

GC content: 52.29

Gene sequence:

>918_bases
ATGATCCCTCTGGTCTATCACACCAGCTATTCCAAGCTGGTGTTGCCCCCAAAGCATCAGTTCCCCATCACCAAGTACGC
CCATCTCCGGCAGCATTTGCTGGAGTATGGGCATGCTTTGGAAGCGCAATTTGTCTCACCTGACCCGGTAGACGCGACCT
TTATTAAAGGCGTTCACGACTCAGATTACGTAGATGCCTTTCTCAATGGCACTCTGTCACCGCAAGCCATTCGCAGGTTG
GGATTTCCCTTGAGCCACGCTCTGGTCGAACGCACCCTGCATTCTTTGGGCGGGTCACTGCTCACGGCCAAGCTTGCCAT
GAGTCGGGGTATTGCGCTGCATCTTGCAGGTGGCTACCACCATGCTCACCGGGATTTTGGCAGCGGATATTGTGTGTTTA
ACGATCTGGTATTGGCGGCAAGGCACCTGATCGACGAGGGCCATGCAAGCCGTGTGATGATCCTTGACTGTGACGTACAT
CAGGGTGATGGCACCGCCACCCTGTGCGCAGACATGGACGATATCATCAGTGTATCTGTGCACTGCGATAGTAATTTTCC
CAGTCGCAAGCCCGCGTCCGACTATGATGTTCCGCTGCCAAAAGGGTTGGAGGACGACGACTATCTCGATGCATTGGAGC
AAGTATTCCAATACCTTCTGCATCTGGAAAAGCCGGATGTCATTCTCTATGATGCTGGAGTCGATGTTCATCATGATGAC
AGGCTGGGGCACCTTAATATCAGTACCCAAGGTCTGCTTCGCAGAGACAAATTGGTTATCACCATGGCGAGGAACGCCGG
GTTGCCATTGGCTGCTGTGATTGGCGGCGGATACTCTGCAAATCCACTACACTTGAGCGAAAGACACAGCCAATTATTTA
TTGCCGCCAATCAGGTATGGCAAGGGGATAATGAATAA

Upstream 100 bases:

>100_bases
GGTGGCGCCCATGCGCAGCAAATGCTGCAATACTGGTGGCTGCAAGCCGACGAGAAAACCCGCAAAGAGTTTATGAGCTG
GGCAATCAAACAGCTCTGAC

Downstream 100 bases:

>100_bases
CGCGGAGCATCTTATGCAACTCGAAATCCGAAACTACTATGAAGTGCTGCTCATGGAAATTTTGTCTGACGAAGGCTTGA
TGGATGAGCTTCCTGAAGAT

Product: histone deacetylase/AcuC/AphA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIPLVYHTSYSKLVLPPKHQFPITKYAHLRQHLLEYGHALEAQFVSPDPVDATFIKGVHDSDYVDAFLNGTLSPQAIRRL
GFPLSHALVERTLHSLGGSLLTAKLAMSRGIALHLAGGYHHAHRDFGSGYCVFNDLVLAARHLIDEGHASRVMILDCDVH
QGDGTATLCADMDDIISVSVHCDSNFPSRKPASDYDVPLPKGLEDDDYLDALEQVFQYLLHLEKPDVILYDAGVDVHHDD
RLGHLNISTQGLLRRDKLVITMARNAGLPLAAVIGGGYSANPLHLSERHSQLFIAANQVWQGDNE

Sequences:

>Translated_305_residues
MIPLVYHTSYSKLVLPPKHQFPITKYAHLRQHLLEYGHALEAQFVSPDPVDATFIKGVHDSDYVDAFLNGTLSPQAIRRL
GFPLSHALVERTLHSLGGSLLTAKLAMSRGIALHLAGGYHHAHRDFGSGYCVFNDLVLAARHLIDEGHASRVMILDCDVH
QGDGTATLCADMDDIISVSVHCDSNFPSRKPASDYDVPLPKGLEDDDYLDALEQVFQYLLHLEKPDVILYDAGVDVHHDD
RLGHLNISTQGLLRRDKLVITMARNAGLPLAAVIGGGYSANPLHLSERHSQLFIAANQVWQGDNE
>Mature_305_residues
MIPLVYHTSYSKLVLPPKHQFPITKYAHLRQHLLEYGHALEAQFVSPDPVDATFIKGVHDSDYVDAFLNGTLSPQAIRRL
GFPLSHALVERTLHSLGGSLLTAKLAMSRGIALHLAGGYHHAHRDFGSGYCVFNDLVLAARHLIDEGHASRVMILDCDVH
QGDGTATLCADMDDIISVSVHCDSNFPSRKPASDYDVPLPKGLEDDDYLDALEQVFQYLLHLEKPDVILYDAGVDVHHDD
RLGHLNISTQGLLRRDKLVITMARNAGLPLAAVIGGGYSANPLHLSERHSQLFIAANQVWQGDNE

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=289, Percent_Identity=31.1418685121107, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI209862883, Length=187, Percent_Identity=37.9679144385027, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI13128860, Length=270, Percent_Identity=28.1481481481481, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI293336691, Length=253, Percent_Identity=26.8774703557312, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI13128862, Length=249, Percent_Identity=28.1124497991968, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI8923769, Length=202, Percent_Identity=27.7227722772277, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI13128864, Length=178, Percent_Identity=29.7752808988764, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI262073092, Length=135, Percent_Identity=30.3703703703704, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193207430, Length=297, Percent_Identity=29.6296296296296, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17508561, Length=269, Percent_Identity=29.368029739777, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17561978, Length=271, Percent_Identity=28.0442804428044, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534739, Length=255, Percent_Identity=29.0196078431373, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI193206283, Length=176, Percent_Identity=28.9772727272727, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540332, Length=176, Percent_Identity=28.9772727272727, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540334, Length=176, Percent_Identity=28.9772727272727, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25154022, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25154020, Length=216, Percent_Identity=28.2407407407407, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323999, Length=211, Percent_Identity=30.8056872037915, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321244, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=185, Percent_Identity=28.6486486486486, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=185, Percent_Identity=25.4054054054054, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649807, Length=296, Percent_Identity=28.0405405405405, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24657891, Length=270, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644244, Length=181, Percent_Identity=29.2817679558011, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281360899, Length=180, Percent_Identity=27.2222222222222, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24642146, Length=180, Percent_Identity=27.2222222222222, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24642144, Length=180, Percent_Identity=27.2222222222222, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24642142, Length=180, Percent_Identity=27.2222222222222, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33627; Mature: 33627

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPLVYHTSYSKLVLPPKHQFPITKYAHLRQHLLEYGHALEAQFVSPDPVDATFIKGVHD
CCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCCCCC
SDYVDAFLNGTLSPQAIRRLGFPLSHALVERTLHSLGGSLLTAKLAMSRGIALHLAGGYH
CHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCEEEEEECCCH
HAHRDFGSGYCVFNDLVLAARHLIDEGHASRVMILDCDVHQGDGTATLCADMDDIISVSV
HHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCCCCCEEEEE
HCDSNFPSRKPASDYDVPLPKGLEDDDYLDALEQVFQYLLHLEKPDVILYDAGVDVHHDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
RLGHLNISTQGLLRRDKLVITMARNAGLPLAAVIGGGYSANPLHLSERHSQLFIAANQVW
CCEEEECCHHHHHCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCEEEEEEEEEC
QGDNE
CCCCC
>Mature Secondary Structure
MIPLVYHTSYSKLVLPPKHQFPITKYAHLRQHLLEYGHALEAQFVSPDPVDATFIKGVHD
CCEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHCCCCCC
SDYVDAFLNGTLSPQAIRRLGFPLSHALVERTLHSLGGSLLTAKLAMSRGIALHLAGGYH
CHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCEEEEEECCCH
HAHRDFGSGYCVFNDLVLAARHLIDEGHASRVMILDCDVHQGDGTATLCADMDDIISVSV
HHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEECCCCCCEEEEE
HCDSNFPSRKPASDYDVPLPKGLEDDDYLDALEQVFQYLLHLEKPDVILYDAGVDVHHDD
EECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCC
RLGHLNISTQGLLRRDKLVITMARNAGLPLAAVIGGGYSANPLHLSERHSQLFIAANQVW
CCEEEECCHHHHHCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCEEEEEEEEEC
QGDNE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]