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The map label for this gene is etfA [H]

Identifier: 119774307

GI number: 119774307

Start: 1427757

End: 1428680

Strand: Direct

Name: etfA [H]

Synonym: Sama_1170

Alternate gene names: 119774307

Gene position: 1427757-1428680 (Clockwise)

Preceding gene: 119774306

Following gene: 119774308

Centisome position: 33.16

GC content: 56.82

Gene sequence:

>924_bases
ATGAGCATTCTCGTCCTTGCAGAACATGATAACGCCAGCCTGAAACTGGATACCGCCAAGGTTGTGAGTGCCGCCAAGGC
CATCGGTGGTGAGGTTCACCTGCTGGTTGCTGGCCATAACTGTGGTGCTGTTGCTGACGCCGCTGCCGCCATCGACGGCG
TTGCCAAGGTGTTGGTTGCCGACAATGCTGCCTATGCTGCGCATCTGGGTGAAAACCTGGCCGCGCTGATGCTGGATTTG
GCTGGCAATTACAGTCACATTCTGGCTGCCGCCAGCTCCATGGGTAAAGATGCGCTGCCACGGGTTGCCGCACTGCTCGA
TGTAGCTCAACTTTCCGAAGTGGTTAAGGTAGTTGATGCCAATACTTTTGTGCGCCCTATCTATGCCGGCAACGCCATGG
CAACTGTGGAGAGCCTGGATGACAAGAAGGTCATGACGGTTCGTCCCAGTGCCTTCGATGCCGCTGCGAATGGTGGCAGC
GCTGCCATTGAAGCACTGGATAAGGTCTTTACCGCCAAGAGCGCCTTTGTATCCCAGGAGCTGACTGTTTCTGAGCGCCC
AGAGCTGGGTAATGCTGGCATTATCGTGTCCGGTGGCCGTGGTATGGGCAGTGGTGAAAACTTTACCCTGCTGGAAAAAC
TGGCCGACAAGCTCGGCGCCGCCGTGGGCGCTTCCCGCGCCGCCGTTGACGCAGGCTTTGTGCCCAACGATTTGCAGGTG
GGTCAAACCGGTAAGATTGTGGCGCCTCAGCTTTACATTGCCGTGGGTATCTCCGGCGCCATCCAGCATCTGGCGGGTAT
GAAAGACTCCAAGGTGATTGTGGCCATCAACAAAGACCCGGAAGCGCCTATCTTCCAGGTGGCGGATTATGCCTTGGAAG
CCGACCTGTTTGAGGCAGTCCCCAAGCTGATAGACTTGCTTTAA

Upstream 100 bases:

>100_bases
CTCAGTGTGGCTGCGCCTGCAACCCGTCAGGCTGGTATCAAGGTGTCTTCCGTTGAAGAGCTGGTGGAAAAACTGAAAAA
CGAAGCAAAGGTGATCTGAT

Downstream 100 bases:

>100_bases
TTTGTGATCTTGGTCACGATATGCGGCCTGGGGGTAGCTTCCCCCGGGCCGCTTGTGTTTTTATGTGCCGCACGCCTGCA
CACAGGCGTCCTGAGTAGAG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSILVLAEHDNASLKLDTAKVVSAAKAIGGEVHLLVAGHNCGAVADAAAAIDGVAKVLVADNAAYAAHLGENLAALMLDL
AGNYSHILAAASSMGKDALPRVAALLDVAQLSEVVKVVDANTFVRPIYAGNAMATVESLDDKKVMTVRPSAFDAAANGGS
AAIEALDKVFTAKSAFVSQELTVSERPELGNAGIIVSGGRGMGSGENFTLLEKLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYALEADLFEAVPKLIDLL

Sequences:

>Translated_307_residues
MSILVLAEHDNASLKLDTAKVVSAAKAIGGEVHLLVAGHNCGAVADAAAAIDGVAKVLVADNAAYAAHLGENLAALMLDL
AGNYSHILAAASSMGKDALPRVAALLDVAQLSEVVKVVDANTFVRPIYAGNAMATVESLDDKKVMTVRPSAFDAAANGGS
AAIEALDKVFTAKSAFVSQELTVSERPELGNAGIIVSGGRGMGSGENFTLLEKLADKLGAAVGASRAAVDAGFVPNDLQV
GQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYALEADLFEAVPKLIDLL
>Mature_306_residues
SILVLAEHDNASLKLDTAKVVSAAKAIGGEVHLLVAGHNCGAVADAAAAIDGVAKVLVADNAAYAAHLGENLAALMLDLA
GNYSHILAAASSMGKDALPRVAALLDVAQLSEVVKVVDANTFVRPIYAGNAMATVESLDDKKVMTVRPSAFDAAANGGSA
AIEALDKVFTAKSAFVSQELTVSERPELGNAGIIVSGGRGMGSGENFTLLEKLADKLGAAVGASRAAVDAGFVPNDLQVG
QTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYALEADLFEAVPKLIDLL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=58.8424437299035, Blast_Score=340, Evalue=6e-94,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=60.5947955390335, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1786226, Length=201, Percent_Identity=34.8258706467662, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787990, Length=248, Percent_Identity=30.6451612903226, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082157, Length=219, Percent_Identity=31.0502283105023, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=306, Percent_Identity=55.2287581699346, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6325261, Length=268, Percent_Identity=48.8805970149254, Blast_Score=250, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=62.5407166123778, Blast_Score=356, Evalue=9e-99,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=62.5407166123778, Blast_Score=356, Evalue=9e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31277; Mature: 31146

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVLAEHDNASLKLDTAKVVSAAKAIGGEVHLLVAGHNCGAVADAAAAIDGVAKVLVA
CEEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEE
DNAAYAAHLGENLAALMLDLAGNYSHILAAASSMGKDALPRVAALLDVAQLSEVVKVVDA
CCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
NTFVRPIYAGNAMATVESLDDKKVMTVRPSAFDAAANGGSAAIEALDKVFTAKSAFVSQE
CCEEEEEECCCHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
LTVSERPELGNAGIIVSGGRGMGSGENFTLLEKLADKLGAAVGASRAAVDAGFVPNDLQV
CCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYALEADLFEAV
CCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
PKLIDLL
HHHHHCC
>Mature Secondary Structure 
SILVLAEHDNASLKLDTAKVVSAAKAIGGEVHLLVAGHNCGAVADAAAAIDGVAKVLVA
EEEEEEECCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEE
DNAAYAAHLGENLAALMLDLAGNYSHILAAASSMGKDALPRVAALLDVAQLSEVVKVVDA
CCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
NTFVRPIYAGNAMATVESLDDKKVMTVRPSAFDAAANGGSAAIEALDKVFTAKSAFVSQE
CCEEEEEECCCHHHHHHHCCCCEEEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
LTVSERPELGNAGIIVSGGRGMGSGENFTLLEKLADKLGAAVGASRAAVDAGFVPNDLQV
CCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEE
GQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYALEADLFEAV
CCCCCEECCEEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
PKLIDLL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]