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The map label for this gene is ptsG [H]

Identifier: 119774270

GI number: 119774270

Start: 1381642

End: 1383099

Strand: Direct

Name: ptsG [H]

Synonym: Sama_1133

Alternate gene names: 119774270

Gene position: 1381642-1383099 (Clockwise)

Preceding gene: 119774269

Following gene: 119774271

Centisome position: 32.09

GC content: 53.98

Gene sequence:

>1458_bases
ATGGCACCAGCAAGTTCAGCACGGCCTGAACGACTAACCCGCCTGAACCGACACTGGTTCAGGTTTGCCCAGCGGCTGTC
GCAAACGCTGCTGATCCCCATTGCCATACTCCCGGCAGCGGGCGTCATGATAGGGATTGCTACTAATCCCTTGCCCTTTA
TTCCAGATGTGGCCAATGTGTTGATGTTGAGTGTGGGCAAGCTCATCTTCGACATTATGCCCATGCTGTTTGCCATCGCG
GTCGCTATTGGTTTCTGCCGCGATCAGGGAATTGCCGCCTTCTCTGCTGCCTTTGGCTACGGTGTGCTGCTGTCTACTCT
GGCAGCAGCGGCCAAGGTTTATCATTTGCCGTCTCACATAGTGTGGGGTACGCCCACCATAGATACCGGCATAGCCGGCG
GCATGTTAGTGGGGGGGATTACCTGCGTTGCGGTGCGGCTCAGTGAAAAGCTCAGGCTGCCTGCCGTGTTTTCGTTTTTT
GAAGGCAGACGCAGCGCCCCGCTGATAATGATCCCCCTGGTGATGTTGCTCGCTGTAATGCTGGCGTTTATCTGGCCGCC
ACTTGCCTTATCCATTGAGCGTTTATCTGACTGGGCCGTGTATCAGGAACCTGCGATTGCCTTCGGATTTTACGGTATGG
TCGAACGGTTGTTGTTGCCGCTTGGGCTGCACCACATCTGGAATGCGCCTTTTTATCTGGAAGTGGGTCAATATGCCCAC
GATGGCGAAATTGTACGGGGGGAGATGGCGAGATATTTTGCTGGCGATCCTTCTGCGGGGAACCTTGCCGGTGGTTACCT
GATTAAAATGTGGGGGCTGCCTGCGGCGGCACTGGCCATATGGCGCTGCGCGGATAGAAATCAACGTAACCGGGTTGCCG
GGGTCATGTTATCTGCCGCGACTGCCAGTTGGCTGACCGGTGTGACAGAGCCGATTGAGTTCGCTTTTTTGTTTGTGGCA
CCACTCTTGTACTTGTGTCATGCCCTGCTGACGGGTCTCGCTTACAGCATCGCCATTTTGCTTGATATGCACCACAGTGT
GGTGTTTTCCCACGGATTGGTGGATTTCGTGCTCCTGTTTCCGCAATCGAGTAATACCCATTGGATTTGGTTCCTGGGGC
CGCTGACATTTGTGATTTATTACATTCTTTTCCGGGCCAGTATTCTGGCGTTTAACCTGAAAACCCCCGGCCGCTTTGAA
GCCGATACAGGACAGAAACGTAATTTGATTGCCATCGTCTCTGCGCTGGGCGGCGGCGGAAACATTGCTGATTTATCAGC
TTGCCTGACCCGTCTGCGGATAAGTGTCGCCGATCCTTCCCAGGTAGACAGACAAAGGTTAATGTCATTGGGTGCCAAAG
GCGTGATAGTGGTGGGCAGTGGTGTTCAGCTGGTGTTTGGTACCAAGGCCGAGACCTTAAGAAAGCTGCTGCAGCGTTAC
CTGGATACACGTAGTTAA

Upstream 100 bases:

>100_bases
TCTTTACTGAGCTGGGGGCCAAACGGGTCTTGCCGCTGCTGCGCATTGATGCAATGGAAACCATGGAACCGGAATTAGAG
GCCAAAACGTGGCTGACGCA

Downstream 100 bases:

>100_bases
GCCGTCTGTTGTGGGATCTTGAAATTTACGGCCAATTTTTTACGTTTCTTCTTGTCTATCTCCCCATGTTTCTCTGATAT
CTGATAAAAATCAGGGTAAT

Product: PTS system, glucose-specific IIBC component

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MAPASSARPERLTRLNRHWFRFAQRLSQTLLIPIAILPAAGVMIGIATNPLPFIPDVANVLMLSVGKLIFDIMPMLFAIA
VAIGFCRDQGIAAFSAAFGYGVLLSTLAAAAKVYHLPSHIVWGTPTIDTGIAGGMLVGGITCVAVRLSEKLRLPAVFSFF
EGRRSAPLIMIPLVMLLAVMLAFIWPPLALSIERLSDWAVYQEPAIAFGFYGMVERLLLPLGLHHIWNAPFYLEVGQYAH
DGEIVRGEMARYFAGDPSAGNLAGGYLIKMWGLPAAALAIWRCADRNQRNRVAGVMLSAATASWLTGVTEPIEFAFLFVA
PLLYLCHALLTGLAYSIAILLDMHHSVVFSHGLVDFVLLFPQSSNTHWIWFLGPLTFVIYYILFRASILAFNLKTPGRFE
ADTGQKRNLIAIVSALGGGGNIADLSACLTRLRISVADPSQVDRQRLMSLGAKGVIVVGSGVQLVFGTKAETLRKLLQRY
LDTRS

Sequences:

>Translated_485_residues
MAPASSARPERLTRLNRHWFRFAQRLSQTLLIPIAILPAAGVMIGIATNPLPFIPDVANVLMLSVGKLIFDIMPMLFAIA
VAIGFCRDQGIAAFSAAFGYGVLLSTLAAAAKVYHLPSHIVWGTPTIDTGIAGGMLVGGITCVAVRLSEKLRLPAVFSFF
EGRRSAPLIMIPLVMLLAVMLAFIWPPLALSIERLSDWAVYQEPAIAFGFYGMVERLLLPLGLHHIWNAPFYLEVGQYAH
DGEIVRGEMARYFAGDPSAGNLAGGYLIKMWGLPAAALAIWRCADRNQRNRVAGVMLSAATASWLTGVTEPIEFAFLFVA
PLLYLCHALLTGLAYSIAILLDMHHSVVFSHGLVDFVLLFPQSSNTHWIWFLGPLTFVIYYILFRASILAFNLKTPGRFE
ADTGQKRNLIAIVSALGGGGNIADLSACLTRLRISVADPSQVDRQRLMSLGAKGVIVVGSGVQLVFGTKAETLRKLLQRY
LDTRS
>Mature_484_residues
APASSARPERLTRLNRHWFRFAQRLSQTLLIPIAILPAAGVMIGIATNPLPFIPDVANVLMLSVGKLIFDIMPMLFAIAV
AIGFCRDQGIAAFSAAFGYGVLLSTLAAAAKVYHLPSHIVWGTPTIDTGIAGGMLVGGITCVAVRLSEKLRLPAVFSFFE
GRRSAPLIMIPLVMLLAVMLAFIWPPLALSIERLSDWAVYQEPAIAFGFYGMVERLLLPLGLHHIWNAPFYLEVGQYAHD
GEIVRGEMARYFAGDPSAGNLAGGYLIKMWGLPAAALAIWRCADRNQRNRVAGVMLSAATASWLTGVTEPIEFAFLFVAP
LLYLCHALLTGLAYSIAILLDMHHSVVFSHGLVDFVLLFPQSSNTHWIWFLGPLTFVIYYILFRASILAFNLKTPGRFEA
DTGQKRNLIAIVSALGGGGNIADLSACLTRLRISVADPSQVDRQRLMSLGAKGVIVVGSGVQLVFGTKAETLRKLLQRYL
DTRS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=472, Percent_Identity=44.4915254237288, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1786894, Length=478, Percent_Identity=34.3096234309623, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI1787908, Length=523, Percent_Identity=32.887189292543, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 52823; Mature: 52692

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPASSARPERLTRLNRHWFRFAQRLSQTLLIPIAILPAAGVMIGIATNPLPFIPDVANV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
LMLSVGKLIFDIMPMLFAIAVAIGFCRDQGIAAFSAAFGYGVLLSTLAAAAKVYHLPSHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VWGTPTIDTGIAGGMLVGGITCVAVRLSEKLRLPAVFSFFEGRRSAPLIMIPLVMLLAVM
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
LAFIWPPLALSIERLSDWAVYQEPAIAFGFYGMVERLLLPLGLHHIWNAPFYLEVGQYAH
HHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
DGEIVRGEMARYFAGDPSAGNLAGGYLIKMWGLPAAALAIWRCADRNQRNRVAGVMLSAA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
TASWLTGVTEPIEFAFLFVAPLLYLCHALLTGLAYSIAILLDMHHSVVFSHGLVDFVLLF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
PQSSNTHWIWFLGPLTFVIYYILFRASILAFNLKTPGRFEADTGQKRNLIAIVSALGGGG
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHEEECCCCCC
NIADLSACLTRLRISVADPSQVDRQRLMSLGAKGVIVVGSGVQLVFGTKAETLRKLLQRY
CHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCEEEEECCEEEEECCCHHHHHHHHHHH
LDTRS
HCCCC
>Mature Secondary Structure 
APASSARPERLTRLNRHWFRFAQRLSQTLLIPIAILPAAGVMIGIATNPLPFIPDVANV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
LMLSVGKLIFDIMPMLFAIAVAIGFCRDQGIAAFSAAFGYGVLLSTLAAAAKVYHLPSHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VWGTPTIDTGIAGGMLVGGITCVAVRLSEKLRLPAVFSFFEGRRSAPLIMIPLVMLLAVM
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
LAFIWPPLALSIERLSDWAVYQEPAIAFGFYGMVERLLLPLGLHHIWNAPFYLEVGQYAH
HHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
DGEIVRGEMARYFAGDPSAGNLAGGYLIKMWGLPAAALAIWRCADRNQRNRVAGVMLSAA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
TASWLTGVTEPIEFAFLFVAPLLYLCHALLTGLAYSIAILLDMHHSVVFSHGLVDFVLLF
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
PQSSNTHWIWFLGPLTFVIYYILFRASILAFNLKTPGRFEADTGQKRNLIAIVSALGGGG
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHEEECCCCCC
NIADLSACLTRLRISVADPSQVDRQRLMSLGAKGVIVVGSGVQLVFGTKAETLRKLLQRY
CHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCCEEEEECCEEEEECCCHHHHHHHHHHH
LDTRS
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]